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The map label for this gene is yccK [H]

Identifier: 17544936

GI number: 17544936

Start: 239883

End: 240911

Strand: Direct

Name: yccK [H]

Synonym: RSc0217

Alternate gene names: 17544936

Gene position: 239883-240911 (Clockwise)

Preceding gene: 17544935

Following gene: 17544937

Centisome position: 6.45

GC content: 67.83

Gene sequence:

>1029_bases
ATGATCGGCTCGATATTCGACCAGCTGTGGGGTGCACGCATGAAGAAACGCCAACTCGGCAGGAGCGGCCTGCAAGTCTC
CGCTCTGGGCTTCGGCTGCATGGGCATGAGCTTCGGCTACGGTCCGACCGCGCTGAGCCGCAATGAGCAGATCGCCGTGA
TTCGCGCGGCTTACGAGCGCGGCGTCACGCTGTTCGATACGGCCGAAGCCTACGGCCCCTGTGTCAATGAAGAACTGGTG
GGCGAGGCGGTGGCGCCATTCCGCAGCCGGATCGTGCTCGCCACGAAGTTCGGCTTCGACATCCGGGACGACCGGATCGT
CGGGCTGAACAGCCGACCCGAGCACATCAGGGCCGTCGCCGAGGCGTCGCTCAAGCGCCTGAGGACGGACGTCATCGACC
TGTTCTACCAGCACCGCGTGGATCCCAATGTGCCCATCGAAGAGGTTGCCGGGGCGCTGAAGGATCTGGTGGCCGAAGGC
AAGGTCAGGCATTTCGGCTTGTCGGAGGCGGGGCCGCGCACCATCCGCCGCGCCCACGCGGTGCATCCGGTGAGCGTGCT
GCAGACGGAGTATTCGCTGTGGACGCGCGATCCCGAGGGCGGCGTGCTGCAGACCTGCGAGGAGTTGGGCATCGGCTTCG
TGCCCTGGAGCCCGCTCGGCCAGGGCTATCTGACCGGCAAGGTGCGCGCGGACACGGCCTTCGACGCGACCGACCTGCGC
AGCACGTTTCCCCGGTTCACGCCCGAGGCCATGCAGGCCAACCAGGCGTTGCTCGCCGGGATCCGGACGATCGCTGACCG
CAAAGGCGCCACGCTCGCGCAGATCGCACTGGCCTGGCTGCTCGCGCAGAAGCCGTGGATCGTGCCGATTCCCGGCACGC
GCAGCGCGGCCCGCCTGGCGGAAAACCTCGGGGCGGCCGACGTGTGCCTGGATGCGGCCGACCTGAGCGAGATCGACGCC
GCGCTGGCCAACGCGCCGGTTGGGCAACCTCGCCTGTCCGACGCGCATCTGCGTTTCATCGACCCATGA

Upstream 100 bases:

>100_bases
GGAGCGGAGGTGCGCTGGCCGCCGTCCTGCTCGTGCCGGCGCGCCGGCCGATGCCCGTGGCCCCAGCGGCGGCGGGCTGA
TCCCTCTCATCCCGTTTCAC

Downstream 100 bases:

>100_bases
GCCCGGGCCGCCGGCCGCTGCCGGAAACAACGATGACCCGAGTCCTGAGACTGGGCGCCAATGGGCCGCTTGCCCGCAAT
ACCACCCGCGTGTTCCTTGC

Product: oxidoreductase transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MIGSIFDQLWGARMKKRQLGRSGLQVSALGFGCMGMSFGYGPTALSRNEQIAVIRAAYERGVTLFDTAEAYGPCVNEELV
GEAVAPFRSRIVLATKFGFDIRDDRIVGLNSRPEHIRAVAEASLKRLRTDVIDLFYQHRVDPNVPIEEVAGALKDLVAEG
KVRHFGLSEAGPRTIRRAHAVHPVSVLQTEYSLWTRDPEGGVLQTCEELGIGFVPWSPLGQGYLTGKVRADTAFDATDLR
STFPRFTPEAMQANQALLAGIRTIADRKGATLAQIALAWLLAQKPWIVPIPGTRSAARLAENLGAADVCLDAADLSEIDA
ALANAPVGQPRLSDAHLRFIDP

Sequences:

>Translated_342_residues
MIGSIFDQLWGARMKKRQLGRSGLQVSALGFGCMGMSFGYGPTALSRNEQIAVIRAAYERGVTLFDTAEAYGPCVNEELV
GEAVAPFRSRIVLATKFGFDIRDDRIVGLNSRPEHIRAVAEASLKRLRTDVIDLFYQHRVDPNVPIEEVAGALKDLVAEG
KVRHFGLSEAGPRTIRRAHAVHPVSVLQTEYSLWTRDPEGGVLQTCEELGIGFVPWSPLGQGYLTGKVRADTAFDATDLR
STFPRFTPEAMQANQALLAGIRTIADRKGATLAQIALAWLLAQKPWIVPIPGTRSAARLAENLGAADVCLDAADLSEIDA
ALANAPVGQPRLSDAHLRFIDP
>Mature_342_residues
MIGSIFDQLWGARMKKRQLGRSGLQVSALGFGCMGMSFGYGPTALSRNEQIAVIRAAYERGVTLFDTAEAYGPCVNEELV
GEAVAPFRSRIVLATKFGFDIRDDRIVGLNSRPEHIRAVAEASLKRLRTDVIDLFYQHRVDPNVPIEEVAGALKDLVAEG
KVRHFGLSEAGPRTIRRAHAVHPVSVLQTEYSLWTRDPEGGVLQTCEELGIGFVPWSPLGQGYLTGKVRADTAFDATDLR
STFPRFTPEAMQANQALLAGIRTIADRKGATLAQIALAWLLAQKPWIVPIPGTRSAARLAENLGAADVCLDAADLSEIDA
ALANAPVGQPRLSDAHLRFIDP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI4504825, Length=347, Percent_Identity=30.5475504322767, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI27436969, Length=332, Percent_Identity=31.3253012048193, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI27436964, Length=332, Percent_Identity=31.6265060240964, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI27436962, Length=332, Percent_Identity=31.3253012048193, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI27436966, Length=332, Percent_Identity=31.3253012048193, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI27436971, Length=332, Percent_Identity=31.3253012048193, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI223718702, Length=189, Percent_Identity=32.8042328042328, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI41152114, Length=186, Percent_Identity=31.1827956989247, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI41327764, Length=182, Percent_Identity=31.3186813186813, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI223718708, Length=121, Percent_Identity=36.3636363636364, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI87081735, Length=327, Percent_Identity=33.9449541284404, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1789375, Length=332, Percent_Identity=32.5301204819277, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1788070, Length=317, Percent_Identity=31.8611987381703, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787674, Length=305, Percent_Identity=29.5081967213115, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788081, Length=323, Percent_Identity=27.2445820433437, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1789199, Length=346, Percent_Identity=27.7456647398844, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI48994888, Length=190, Percent_Identity=33.1578947368421, Blast_Score=76, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6325169, Length=334, Percent_Identity=26.9461077844311, Blast_Score=112, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6323998, Length=328, Percent_Identity=26.5243902439024, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6325384, Length=328, Percent_Identity=27.1341463414634, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319958, Length=297, Percent_Identity=25.2525252525253, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322615, Length=250, Percent_Identity=26, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319951, Length=298, Percent_Identity=24.1610738255034, Blast_Score=82, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24640980, Length=359, Percent_Identity=24.7910863509749, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45549126, Length=359, Percent_Identity=24.7910863509749, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24646155, Length=182, Percent_Identity=31.3186813186813, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37140; Mature: 37140

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGSIFDQLWGARMKKRQLGRSGLQVSALGFGCMGMSFGYGPTALSRNEQIAVIRAAYER
CCHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHCCCCCCCCCCCCCCCEEEEEEHHHC
GVTLFDTAEAYGPCVNEELVGEAVAPFRSRIVLATKFGFDIRDDRIVGLNSRPEHIRAVA
CCEEEECHHHHCCCCCHHHHHHHHHHHHHCEEEEEECCCCCCCCEEEECCCCHHHHHHHH
EASLKRLRTDVIDLFYQHRVDPNVPIEEVAGALKDLVAEGKVRHFGLSEAGPRTIRRAHA
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHC
VHPVSVLQTEYSLWTRDPEGGVLQTCEELGIGFVPWSPLGQGYLTGKVRADTAFDATDLR
CCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCEEECEEECCCCCCHHHHH
STFPRFTPEAMQANQALLAGIRTIADRKGATLAQIALAWLLAQKPWIVPIPGTRSAARLA
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHH
ENLGAADVCLDAADLSEIDAALANAPVGQPRLSDAHLRFIDP
HHCCHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCC
>Mature Secondary Structure
MIGSIFDQLWGARMKKRQLGRSGLQVSALGFGCMGMSFGYGPTALSRNEQIAVIRAAYER
CCHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHCCCCCCCCCCCCCCCEEEEEEHHHC
GVTLFDTAEAYGPCVNEELVGEAVAPFRSRIVLATKFGFDIRDDRIVGLNSRPEHIRAVA
CCEEEECHHHHCCCCCHHHHHHHHHHHHHCEEEEEECCCCCCCCEEEECCCCHHHHHHHH
EASLKRLRTDVIDLFYQHRVDPNVPIEEVAGALKDLVAEGKVRHFGLSEAGPRTIRRAHA
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHC
VHPVSVLQTEYSLWTRDPEGGVLQTCEELGIGFVPWSPLGQGYLTGKVRADTAFDATDLR
CCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCEEECEEECCCCCCHHHHH
STFPRFTPEAMQANQALLAGIRTIADRKGATLAQIALAWLLAQKPWIVPIPGTRSAARLA
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHH
ENLGAADVCLDAADLSEIDAALANAPVGQPRLSDAHLRFIDP
HHCCHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]