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The map label for this gene is opdE [H]

Identifier: 17544926

GI number: 17544926

Start: 230100

End: 231326

Strand: Direct

Name: opdE [H]

Synonym: RSc0207

Alternate gene names: 17544926

Gene position: 230100-231326 (Clockwise)

Preceding gene: 17544925

Following gene: 17544927

Centisome position: 6.19

GC content: 64.47

Gene sequence:

>1227_bases
GTGGAAGGACACACGCACGCTGATCCGCATCACGCGGAGGTCTCCGGCGGGCGACCGGCATGGGGCGCGGTGTTCGCGCT
GTCGCTCGCCGCATTCATACTGGTTGCATCGGAATTCATGCCGGTGAGTCTGCTGACACCCATCGCGGGGAGCCTTCATC
TCACTGAAGGTCAAGCGGGGCAGGCCATCTCCGTTTCTGGGGCGTTTGCCTTGCTGACCAGCCTGTTCATCCCGGCGATG
GCAGCCCGGCTCGATCGCAAAGTGCTCCTTCTGCTGTTGACGCTGTTGACGGTCGTCTCCGGTGTAGTGGTCACGCTGGC
GCCCGACTACTCGACATTCATCATCGGTCGGGCACTGATCGGTGTGGCCATTGGCGGTTTCTGGTCGATGTCGGCAGCGA
CGGCCATGCGGCTCGTGCCGCATCATGACGTGCCGCACGCTTTGGCGATCGTCAACGGTGGTAACGCTCTCGCAACGGTG
TTGGCCGCGCCGCTTGGCAGCTTGCTTGGCGCCGTCGTTGGCTGGCGCGGTGCGTTTTTCTGCATCGTGCCTGTGGCGAC
GATCGCGCTGGTCTGGCAATGGATGACCCTGCCCGCGCTGAAAGCTGACAGCAGCCCTGGCGCCGCCGGTGATGTCTTCA
CGCTGTTGAGGCGGCCTGCGGTGGCGTTGGGCATGGCGGCGGTTGGCCTCTTCTTCATGGGCCAGTTCATGCTGTTCACC
TACCTGCGGCCCTTTCTTGAAACGGTGACCAACACCAGGGCTTCCACACTCTCGTTCGTGTTGCTTGTCATCGGCGTGGC
GGGTTTCGTGGGGACCGCCGTGATTGGCACGTTTCTAAAAGATGGCCTCTACCGGACGCTGATCGTCATTCCTGTGTTGA
TGGCAGGGATTGCACTGGCGCTTGCGTCGTTCGGTGGCTCACTGGCCGCCTCCACGATCCTTCTCGCCATTTGGGGGCTG
GTCGCGACCGCTGCTCCGGTCGGCTGGTGGACATGGCTGGCTAGAACACTGCCGCAAGACGCGGAGACCGGCGGCGGACT
CATGGTGGCGATCATCCAGCTGGCGATCACGTTGGGCGCAGCCGGCGGCGGCGCAATGTTCGACGCGGGCGGCTACCGCG
CGACCTTTGGCATGAGTGCGGCTGTGCTGGTCGCGGCAGCGGTGCTTGCCATACTGGCCGCACGTGCGGGCACGCGAACG
GTTCGGGCCGGCGCAGCCGTCGCTTGA

Upstream 100 bases:

>100_bases
GACAAGCTGACCGCGTTCTTTCGGGCCAACCTGAGATAACGGGTAAGCATCCCGGTTCCATTCAAGTCATTCTTGACGTT
CAAAGAGGTCGATCCAGAAA

Downstream 100 bases:

>100_bases
CGTGCTGCTCAAGTGCCGTAGATTCGCTCGTCAAACCTGGAGTTTGCCCCGAGCGCGCAACAGGTTGGATGTTGAGTGTC
ACCTGCTAGCGGCTGTTGTA

Product: transporter transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MEGHTHADPHHAEVSGGRPAWGAVFALSLAAFILVASEFMPVSLLTPIAGSLHLTEGQAGQAISVSGAFALLTSLFIPAM
AARLDRKVLLLLLTLLTVVSGVVVTLAPDYSTFIIGRALIGVAIGGFWSMSAATAMRLVPHHDVPHALAIVNGGNALATV
LAAPLGSLLGAVVGWRGAFFCIVPVATIALVWQWMTLPALKADSSPGAAGDVFTLLRRPAVALGMAAVGLFFMGQFMLFT
YLRPFLETVTNTRASTLSFVLLVIGVAGFVGTAVIGTFLKDGLYRTLIVIPVLMAGIALALASFGGSLAASTILLAIWGL
VATAAPVGWWTWLARTLPQDAETGGGLMVAIIQLAITLGAAGGGAMFDAGGYRATFGMSAAVLVAAAVLAILAARAGTRT
VRAGAAVA

Sequences:

>Translated_408_residues
MEGHTHADPHHAEVSGGRPAWGAVFALSLAAFILVASEFMPVSLLTPIAGSLHLTEGQAGQAISVSGAFALLTSLFIPAM
AARLDRKVLLLLLTLLTVVSGVVVTLAPDYSTFIIGRALIGVAIGGFWSMSAATAMRLVPHHDVPHALAIVNGGNALATV
LAAPLGSLLGAVVGWRGAFFCIVPVATIALVWQWMTLPALKADSSPGAAGDVFTLLRRPAVALGMAAVGLFFMGQFMLFT
YLRPFLETVTNTRASTLSFVLLVIGVAGFVGTAVIGTFLKDGLYRTLIVIPVLMAGIALALASFGGSLAASTILLAIWGL
VATAAPVGWWTWLARTLPQDAETGGGLMVAIIQLAITLGAAGGGAMFDAGGYRATFGMSAAVLVAAAVLAILAARAGTRT
VRAGAAVA
>Mature_408_residues
MEGHTHADPHHAEVSGGRPAWGAVFALSLAAFILVASEFMPVSLLTPIAGSLHLTEGQAGQAISVSGAFALLTSLFIPAM
AARLDRKVLLLLLTLLTVVSGVVVTLAPDYSTFIIGRALIGVAIGGFWSMSAATAMRLVPHHDVPHALAIVNGGNALATV
LAAPLGSLLGAVVGWRGAFFCIVPVATIALVWQWMTLPALKADSSPGAAGDVFTLLRRPAVALGMAAVGLFFMGQFMLFT
YLRPFLETVTNTRASTLSFVLLVIGVAGFVGTAVIGTFLKDGLYRTLIVIPVLMAGIALALASFGGSLAASTILLAIWGL
VATAAPVGWWTWLARTLPQDAETGGGLMVAIIQLAITLGAAGGGAMFDAGGYRATFGMSAAVLVAAAVLAILAARAGTRT
VRAGAAVA

Specific function: Regulates the expression of oprD which encodes the imipenem-specific porin [H]

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis ywfA [H]

Homologues:

Organism=Escherichia coli, GI145693198, Length=372, Percent_Identity=39.7849462365591, Blast_Score=257, Evalue=9e-70,
Organism=Escherichia coli, GI1787808, Length=232, Percent_Identity=32.3275862068966, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1786595, Length=380, Percent_Identity=27.6315789473684, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787947, Length=300, Percent_Identity=27.6666666666667, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41635; Mature: 41635

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGHTHADPHHAEVSGGRPAWGAVFALSLAAFILVASEFMPVSLLTPIAGSLHLTEGQAG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEECCCCCC
QAISVSGAFALLTSLFIPAMAARLDRKVLLLLLTLLTVVSGVVVTLAPDYSTFIIGRALI
CEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHH
GVAIGGFWSMSAATAMRLVPHHDVPHALAIVNGGNALATVLAAPLGSLLGAVVGWRGAFF
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
CIVPVATIALVWQWMTLPALKADSSPGAAGDVFTLLRRPAVALGMAAVGLFFMGQFMLFT
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
YLRPFLETVTNTRASTLSFVLLVIGVAGFVGTAVIGTFLKDGLYRTLIVIPVLMAGIALA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LASFGGSLAASTILLAIWGLVATAAPVGWWTWLARTLPQDAETGGGLMVAIIQLAITLGA
HHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCC
AGGGAMFDAGGYRATFGMSAAVLVAAAVLAILAARAGTRTVRAGAAVA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCC
>Mature Secondary Structure
MEGHTHADPHHAEVSGGRPAWGAVFALSLAAFILVASEFMPVSLLTPIAGSLHLTEGQAG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEECCCCCC
QAISVSGAFALLTSLFIPAMAARLDRKVLLLLLTLLTVVSGVVVTLAPDYSTFIIGRALI
CEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHH
GVAIGGFWSMSAATAMRLVPHHDVPHALAIVNGGNALATVLAAPLGSLLGAVVGWRGAFF
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
CIVPVATIALVWQWMTLPALKADSSPGAAGDVFTLLRRPAVALGMAAVGLFFMGQFMLFT
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
YLRPFLETVTNTRASTLSFVLLVIGVAGFVGTAVIGTFLKDGLYRTLIVIPVLMAGIALA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LASFGGSLAASTILLAIWGLVATAAPVGWWTWLARTLPQDAETGGGLMVAIIQLAITLGA
HHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCC
AGGGAMFDAGGYRATFGMSAAVLVAAAVLAILAARAGTRTVRAGAAVA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1427017; 10984043 [H]