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The map label for this gene is ampG [H]

Identifier: 17544873

GI number: 17544873

Start: 173974

End: 175254

Strand: Direct

Name: ampG [H]

Synonym: RSc0154

Alternate gene names: 17544873

Gene position: 173974-175254 (Clockwise)

Preceding gene: 17544870

Following gene: 17544875

Centisome position: 4.68

GC content: 70.65

Gene sequence:

>1281_bases
ATGACCTTCCACGATTACCTCGACGTGTTCCGCAACCGCCGCATCGGCGCGATGCTGCTGCTGGGCTTCGCCTCCGGCCT
GCCGCTGGCGCTGACCTCCGGCACGCTGCAGGCATGGATGACGGTGGAGGGACTGGACATCCGCACCATCGGGCTGTTCT
CGCTGGTGGGGCAGGCGTACATCTTCAAGTTCCTGTGGGCGCCGCTGATGGATCGCTTCACGCCGCCGCTGATCGGCCGG
CGGCGCGGCTGGCTGGTGCTGACGCAGGCCGGGCTGGCGGCGTCGATCGCGGCCATGGCGTTCTGTCCGCCGCATGCCGC
GCTGTGGGCGCTGGCGGGCCTGGCGGTGCTGGTGGCCTTCCTCTCGGCCTCGCAGGACATCGTCTTCGATGCCTACAGCA
CCGACGTGCTGCATGCCAGCGAGCGCGGCGTGGGCGCGGCGGTCAAGGTGCTCGGCTACCGGCTGGCGATGCTGGTCTCC
GGCGGCCTGGCGCTGTGGCTGGCCGATCGCGTGATGGGCTGGAGCAGCATGTACCTGCTGATGGCCGGGCTGATGGCGCT
ATTTGTCCTGGCGACGCTGTGGTCGCCCGAGCCGGAGGCGGCGGCGCGGCCGCCCCGCAGCCTGCAGGAGGCGGTGGTCG
GGCCGCTGCGGGATTTCTTCGCGCGCCGCGGCGCCTGGGCGCTGCTGGCGCTGATCGTGCTCTACAAGCTGGGCGATGCG
TTCGCCGGCAGCCTGTCGACCACGTTCCTGATCCGCGGCGTCGGCTTCTCGGCGGGCGAGGTGGGCATCGTCAACAAGAC
GCTGGGCCTGGTCGCCACCATCATCGGCGCGCTCTACGGCGGCACGCTGATGGTGCGGCTGGGGCTGGTGCGCGCGCTGC
TGCTGTTCGGCGTGCTGCAGGCGGTGTCCAACCTGGGCTACTGGGTGCTGGCCGTCACGCCGCAGCACTTGTGGACCATG
GCGCTGGCCATCGGCATCGAGAACCTCTGCGGCGGCATGGGCACGGCCGCCTTCGTGGCGCTGCTGATGGCGCTGTGCAA
CCGCTCGTTCTCGGCGACGCAGTATGCGCTGCTGTCGGCGCTGGCCTCCATCGGCCGCGTCTATGTCGGGCCGACTTCCG
GCTACCTGGTGGAGGCCTACGGCTGGCCCGCGTTTTACCTGATGACGGTGGCGTTCGCCTTCCCCGGGCTGGCGCTGCTG
TGGTGCATGCGCGGCACCATCGGCCGCTACGAGGCCGAGCAGGCGGAGCGTGCCCTGGCCGCGAAGCCGACGTCAGCCTA
G

Upstream 100 bases:

>100_bases
GGCATGCGGAGGGAGGCTGGGTCGACTGGGTAATAATATCGGTCAATGCGTCCTGCCGCGCTTCGCGGCAACCCCTATCG
TCCGCCAGCCCTCCCGCCGC

Downstream 100 bases:

>100_bases
CCGGTCCGAGCGGTCCGCATCGGCAAAGCCCGCCAGCGGCAGCGCCGCGTCGAGGCCCCGGCCGAGCGCGATGGCCTTGA
ACAGCTCGCCCATCTCCGCT

Product: muropeptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MTFHDYLDVFRNRRIGAMLLLGFASGLPLALTSGTLQAWMTVEGLDIRTIGLFSLVGQAYIFKFLWAPLMDRFTPPLIGR
RRGWLVLTQAGLAASIAAMAFCPPHAALWALAGLAVLVAFLSASQDIVFDAYSTDVLHASERGVGAAVKVLGYRLAMLVS
GGLALWLADRVMGWSSMYLLMAGLMALFVLATLWSPEPEAAARPPRSLQEAVVGPLRDFFARRGAWALLALIVLYKLGDA
FAGSLSTTFLIRGVGFSAGEVGIVNKTLGLVATIIGALYGGTLMVRLGLVRALLLFGVLQAVSNLGYWVLAVTPQHLWTM
ALAIGIENLCGGMGTAAFVALLMALCNRSFSATQYALLSALASIGRVYVGPTSGYLVEAYGWPAFYLMTVAFAFPGLALL
WCMRGTIGRYEAEQAERALAAKPTSA

Sequences:

>Translated_426_residues
MTFHDYLDVFRNRRIGAMLLLGFASGLPLALTSGTLQAWMTVEGLDIRTIGLFSLVGQAYIFKFLWAPLMDRFTPPLIGR
RRGWLVLTQAGLAASIAAMAFCPPHAALWALAGLAVLVAFLSASQDIVFDAYSTDVLHASERGVGAAVKVLGYRLAMLVS
GGLALWLADRVMGWSSMYLLMAGLMALFVLATLWSPEPEAAARPPRSLQEAVVGPLRDFFARRGAWALLALIVLYKLGDA
FAGSLSTTFLIRGVGFSAGEVGIVNKTLGLVATIIGALYGGTLMVRLGLVRALLLFGVLQAVSNLGYWVLAVTPQHLWTM
ALAIGIENLCGGMGTAAFVALLMALCNRSFSATQYALLSALASIGRVYVGPTSGYLVEAYGWPAFYLMTVAFAFPGLALL
WCMRGTIGRYEAEQAERALAAKPTSA
>Mature_425_residues
TFHDYLDVFRNRRIGAMLLLGFASGLPLALTSGTLQAWMTVEGLDIRTIGLFSLVGQAYIFKFLWAPLMDRFTPPLIGRR
RGWLVLTQAGLAASIAAMAFCPPHAALWALAGLAVLVAFLSASQDIVFDAYSTDVLHASERGVGAAVKVLGYRLAMLVSG
GLALWLADRVMGWSSMYLLMAGLMALFVLATLWSPEPEAAARPPRSLQEAVVGPLRDFFARRGAWALLALIVLYKLGDAF
AGSLSTTFLIRGVGFSAGEVGIVNKTLGLVATIIGALYGGTLMVRLGLVRALLLFGVLQAVSNLGYWVLAVTPQHLWTMA
LAIGIENLCGGMGTAAFVALLMALCNRSFSATQYALLSALASIGRVYVGPTSGYLVEAYGWPAFYLMTVAFAFPGLALLW
CMRGTIGRYEAEQAERALAAKPTSA

Specific function: Probably acts as a permease in the beta-lactamase induction system and in peptidoglycan recycling [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Homo sapiens, GI19923957, Length=407, Percent_Identity=29.4840294840295, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1786636, Length=419, Percent_Identity=65.1551312649165, Blast_Score=539, Evalue=1e-154,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004752
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45520; Mature: 45388

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFHDYLDVFRNRRIGAMLLLGFASGLPLALTSGTLQAWMTVEGLDIRTIGLFSLVGQAY
CCHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCHHHHEEECCCCCHHHHHHHHHHHHH
IFKFLWAPLMDRFTPPLIGRRRGWLVLTQAGLAASIAAMAFCPPHAALWALAGLAVLVAF
HHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LSASQDIVFDAYSTDVLHASERGVGAAVKVLGYRLAMLVSGGLALWLADRVMGWSSMYLL
HHCCCCEEEECCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHH
MAGLMALFVLATLWSPEPEAAARPPRSLQEAVVGPLRDFFARRGAWALLALIVLYKLGDA
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
FAGSLSTTFLIRGVGFSAGEVGIVNKTLGLVATIIGALYGGTLMVRLGLVRALLLFGVLQ
HHCHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVSNLGYWVLAVTPQHLWTMALAIGIENLCGGMGTAAFVALLMALCNRSFSATQYALLSA
HHHCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
LASIGRVYVGPTSGYLVEAYGWPAFYLMTVAFAFPGLALLWCMRGTIGRYEAEQAERALA
HHHHCEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
AKPTSA
CCCCCC
>Mature Secondary Structure 
TFHDYLDVFRNRRIGAMLLLGFASGLPLALTSGTLQAWMTVEGLDIRTIGLFSLVGQAY
CHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCHHHHEEECCCCCHHHHHHHHHHHHH
IFKFLWAPLMDRFTPPLIGRRRGWLVLTQAGLAASIAAMAFCPPHAALWALAGLAVLVAF
HHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LSASQDIVFDAYSTDVLHASERGVGAAVKVLGYRLAMLVSGGLALWLADRVMGWSSMYLL
HHCCCCEEEECCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHH
MAGLMALFVLATLWSPEPEAAARPPRSLQEAVVGPLRDFFARRGAWALLALIVLYKLGDA
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
FAGSLSTTFLIRGVGFSAGEVGIVNKTLGLVATIIGALYGGTLMVRLGLVRALLLFGVLQ
HHCHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVSNLGYWVLAVTPQHLWTMALAIGIENLCGGMGTAAFVALLMALCNRSFSATQYALLSA
HHHCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
LASIGRVYVGPTSGYLVEAYGWPAFYLMTVAFAFPGLALLWCMRGTIGRYEAEQAERALA
HHHHCEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
AKPTSA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]