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The map label for this gene is xerC

Identifier: 17544771

GI number: 17544771

Start: 57356

End: 58345

Strand: Reverse

Name: xerC

Synonym: RSc0052

Alternate gene names: 17544771

Gene position: 58345-57356 (Counterclockwise)

Preceding gene: 17544772

Following gene: 17544770

Centisome position: 1.57

GC content: 71.31

Gene sequence:

>990_bases
ATGCCGCCGTCTGCACCCGACGATGACCGCGACGCCCCGGCGCCGCCCCATCCGCAGATCGGGGCCTACCTCGACGCGCT
GAAGTTCGAGCGCAAGCTGTCGCAGCACACGCTGGCGAGCTACGCCCGCGAGCTGGCCGTGCTGCAGCAGCTCGGCGCGC
GGTTCGCGGCGGGCATCGACCTGATGCGGCTGCAGCCGCACCACATCCGCCGCATGATGGCGCAGCTGCACGGCGGCGGC
CTGTCGGGCCGCAGCATCGCGCGGGCACTGTCGGCGTGGCGCGGCTGGTACCAGTGGCTGGCGCTGCGTGATGCGGCCGT
CACCGCCAACCCGGTCGACGGCATCCGCGCGCCCAAGAGCCCGAAGCGGCTGCCCAAGGCGCTCTCGGTCGAACAGGCCG
TCGCACTGATGGAGCAGTTGCCCGGCGACGACCCCGAAGCCGTCCGCGACCGCGCCGTCAACGAGCTGTTCTATTCGTGC
GGGCTGCGGCTGTCGGAACTGGTCGGGCTCGACCTGCGCCACGCGCAGGCCGGCGACTACGCCTCGGCGAGCTGGCTCGA
CCTGGAGGCTCGCGAAGTGACGGTGCTCGGCAAGGGCAACAAGCGCCGGACCGTACCGGTGGGCAGCAAGGCTGCCGAGG
CCCTGGCCGCGTGGCTGGCGGTGCGCCCGCAGCTGGCGCAGCCTGACGCCGCCCCGGAAGACGCCCACGCGCTGTTCCTG
TCGGCGCGCGGCAAGCGGCTGGCGCAGCGGCAGATCCAGACCCGGATGAAGCGCAACGCCATCGCCGCGGGCGTGCCGGC
GGACGTGCATCCGCACGTGCTGCGGCATTCGTTCGCCACGCACATGCTGCAATCCTCCGGCGACCTGCGCGCGGTGCAGG
AACTGCTCGGGCACGCCAGCATCGCCAGCACGCAGGTTTATACTTCGCTCGATTTCCAGCACCTGGCCAAGATCTACGAT
CAGGCCCACCCGCGCGCAAAGAAGAAATGA

Upstream 100 bases:

>100_bases
CGTCGCTTCCACGATGGCATGGGCACCACGTATCTCGCGCAGATCGGCGAGCTGGCCGCCGCTGCGCTGAACCGCCTGCG
CGACTGATCGCGCCGCCGCC

Downstream 100 bases:

>100_bases
CGCGCCGCCCGGGCAACCGGGCATTCCCATCCCAGCCGTATGCAAACCCTGATTCTCAAGCCCGGCAAGGAGCGCTCGCT
GCTGCGCCGGCACCCGTGGA

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MPPSAPDDDRDAPAPPHPQIGAYLDALKFERKLSQHTLASYARELAVLQQLGARFAAGIDLMRLQPHHIRRMMAQLHGGG
LSGRSIARALSAWRGWYQWLALRDAAVTANPVDGIRAPKSPKRLPKALSVEQAVALMEQLPGDDPEAVRDRAVNELFYSC
GLRLSELVGLDLRHAQAGDYASASWLDLEAREVTVLGKGNKRRTVPVGSKAAEALAAWLAVRPQLAQPDAAPEDAHALFL
SARGKRLAQRQIQTRMKRNAIAAGVPADVHPHVLRHSFATHMLQSSGDLRAVQELLGHASIASTQVYTSLDFQHLAKIYD
QAHPRAKKK

Sequences:

>Translated_329_residues
MPPSAPDDDRDAPAPPHPQIGAYLDALKFERKLSQHTLASYARELAVLQQLGARFAAGIDLMRLQPHHIRRMMAQLHGGG
LSGRSIARALSAWRGWYQWLALRDAAVTANPVDGIRAPKSPKRLPKALSVEQAVALMEQLPGDDPEAVRDRAVNELFYSC
GLRLSELVGLDLRHAQAGDYASASWLDLEAREVTVLGKGNKRRTVPVGSKAAEALAAWLAVRPQLAQPDAAPEDAHALFL
SARGKRLAQRQIQTRMKRNAIAAGVPADVHPHVLRHSFATHMLQSSGDLRAVQELLGHASIASTQVYTSLDFQHLAKIYD
QAHPRAKKK
>Mature_328_residues
PPSAPDDDRDAPAPPHPQIGAYLDALKFERKLSQHTLASYARELAVLQQLGARFAAGIDLMRLQPHHIRRMMAQLHGGGL
SGRSIARALSAWRGWYQWLALRDAAVTANPVDGIRAPKSPKRLPKALSVEQAVALMEQLPGDDPEAVRDRAVNELFYSCG
LRLSELVGLDLRHAQAGDYASASWLDLEAREVTVLGKGNKRRTVPVGSKAAEALAAWLAVRPQLAQPDAAPEDAHALFLS
ARGKRLAQRQIQTRMKRNAIAAGVPADVHPHVLRHSFATHMLQSSGDLRAVQELLGHASIASTQVYTSLDFQHLAKIYDQ
AHPRAKKK

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1790244, Length=315, Percent_Identity=45.0793650793651, Blast_Score=245, Evalue=4e-66,
Organism=Escherichia coli, GI1789261, Length=311, Percent_Identity=37.2990353697749, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1790767, Length=185, Percent_Identity=30.2702702702703, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790768, Length=191, Percent_Identity=28.7958115183246, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC1_RALSO (Q8Y3C8)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_518173.1
- ProteinModelPortal:   Q8Y3C8
- SMR:   Q8Y3C8
- GeneID:   1218854
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc0052
- NMPDR:   fig|267608.1.peg.52
- HOGENOM:   HBG727654
- OMA:   TTEGIRD
- ProtClustDB:   PRK00236
- BioCyc:   RSOL267608:RSC0052-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10
- TIGRFAMs:   TIGR02224

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 36009; Mature: 35877

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: NA

Important sites: ACT_SITE 163-163 ACT_SITE 198-198 ACT_SITE 272-272 ACT_SITE 275-275 ACT_SITE 298-298 ACT_SITE 307-307

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPSAPDDDRDAPAPPHPQIGAYLDALKFERKLSQHTLASYARELAVLQQLGARFAAGID
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LMRLQPHHIRRMMAQLHGGGLSGRSIARALSAWRGWYQWLALRDAAVTANPVDGIRAPKS
HHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PKRLPKALSVEQAVALMEQLPGDDPEAVRDRAVNELFYSCGLRLSELVGLDLRHAQAGDY
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHCCCCCC
ASASWLDLEAREVTVLGKGNKRRTVPVGSKAAEALAAWLAVRPQLAQPDAAPEDAHALFL
CCCCEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
SARGKRLAQRQIQTRMKRNAIAAGVPADVHPHVLRHSFATHMLQSSGDLRAVQELLGHAS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
IASTQVYTSLDFQHLAKIYDQAHPRAKKK
HHHHHHHHHCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PPSAPDDDRDAPAPPHPQIGAYLDALKFERKLSQHTLASYARELAVLQQLGARFAAGID
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LMRLQPHHIRRMMAQLHGGGLSGRSIARALSAWRGWYQWLALRDAAVTANPVDGIRAPKS
HHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PKRLPKALSVEQAVALMEQLPGDDPEAVRDRAVNELFYSCGLRLSELVGLDLRHAQAGDY
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHCCCCCC
ASASWLDLEAREVTVLGKGNKRRTVPVGSKAAEALAAWLAVRPQLAQPDAAPEDAHALFL
CCCCEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
SARGKRLAQRQIQTRMKRNAIAAGVPADVHPHVLRHSFATHMLQSSGDLRAVQELLGHAS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
IASTQVYTSLDFQHLAKIYDQAHPRAKKK
HHHHHHHHHCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852