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The map label for this gene is argB

Identifier: 17544752

GI number: 17544752

Start: 38758

End: 39690

Strand: Reverse

Name: argB

Synonym: RSc0033

Alternate gene names: 17544752

Gene position: 39690-38758 (Counterclockwise)

Preceding gene: 17544756

Following gene: 17544751

Centisome position: 1.07

GC content: 64.09

Gene sequence:

>933_bases
ATGACCGCTTCTGTTGCCGCCGCCCCCGACCCTGCTGGCCTCGATCCCGAACTCGCCCATATCGCGCCCGCGCTCAAGGC
CGAGATCCTCGCGCAGGCGCTGCCCTATATCCGCAAGTTCCACGGCAAGACCATCGTCATCAAGTACGGCGGCAACGCCA
TGACGGAAGAGAAGCTCAAGCACGGCTTCGCGCGCGACGTGATCCTGCTCAAGCTGGTCGGCATGAACCCGGTGGTGGTG
CACGGCGGCGGTCCGCAGATCGACGATGCGCTCAAGAAGGTCGGCAAGACCGGCACCTTCATCCAGGGCATGCGCGTGAC
CGATGAAGAGACCATGGAAGTGGTCGAGTGGGTGCTCGGCGGCGAAGTCCAGCAGGACATCGTCATGCTGATCAACCAGT
ACGGCGGCCAGGCGGTCGGCCTGACCGGCAAGGACGGCGGCCTGATCCGCGCCAAGAAGCTGAAGATGCCGGACCGCGAA
CAGCCCGGCCAGTTCATCGACATCGGCTTCGTGGGCGATATCGAGACCATCAACCCGGCTGTGGTCCGCGCGCTGCAGGA
CGACGCCTTCATTCCCGTCATCTCGCCGATCGGCTTCTCCGACGACGGCCAGGCCTACAACATCAACGCCGACGTGGTGG
CCGGCAAGATGGCCGAGATCCTCAAGGCCGAGAAGCTGGTGATGATGACCAACATCCCCGGCGTGATGGACAAGCAGGGC
AACCTGCTGACCGACCTGTCGGCGCGCGAGATCGACGAGCTGTTCGCCGACGGCACCATCTCGGGCGGCATGCTGCCGAA
GATTTCGTCGGCGCTGGATGCCGCCAAGAGCGGCGTGAACTCGGTGCACATCATCGATGGCCGCATCGAGCATTCGCTGC
TGCTGGAAATCCTGACCGAACAGGCGTTCGGCACGATGATCCGCTCGCACTGA

Upstream 100 bases:

>100_bases
TCTTGTAAAATCCCGCCTGCCGAAAAAAGGCGGCGCCGCTTTGTGCAGCGCGCGACATTCGGCGTTCCATCATACCCCGC
CCAATCCGGATGTCACCGTC

Downstream 100 bases:

>100_bases
TGCGCACGGCCCGGGCGCCCCGGGCGCGCCATGCCGGGCGCGCCTGGCCGCGAGAGGTTGCGGCGCCCGGCCTGCCGCGG
CGGCAGCCGGTCTGGCTGTT

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MTASVAAAPDPAGLDPELAHIAPALKAEILAQALPYIRKFHGKTIVIKYGGNAMTEEKLKHGFARDVILLKLVGMNPVVV
HGGGPQIDDALKKVGKTGTFIQGMRVTDEETMEVVEWVLGGEVQQDIVMLINQYGGQAVGLTGKDGGLIRAKKLKMPDRE
QPGQFIDIGFVGDIETINPAVVRALQDDAFIPVISPIGFSDDGQAYNINADVVAGKMAEILKAEKLVMMTNIPGVMDKQG
NLLTDLSAREIDELFADGTISGGMLPKISSALDAAKSGVNSVHIIDGRIEHSLLLEILTEQAFGTMIRSH

Sequences:

>Translated_310_residues
MTASVAAAPDPAGLDPELAHIAPALKAEILAQALPYIRKFHGKTIVIKYGGNAMTEEKLKHGFARDVILLKLVGMNPVVV
HGGGPQIDDALKKVGKTGTFIQGMRVTDEETMEVVEWVLGGEVQQDIVMLINQYGGQAVGLTGKDGGLIRAKKLKMPDRE
QPGQFIDIGFVGDIETINPAVVRALQDDAFIPVISPIGFSDDGQAYNINADVVAGKMAEILKAEKLVMMTNIPGVMDKQG
NLLTDLSAREIDELFADGTISGGMLPKISSALDAAKSGVNSVHIIDGRIEHSLLLEILTEQAFGTMIRSH
>Mature_309_residues
TASVAAAPDPAGLDPELAHIAPALKAEILAQALPYIRKFHGKTIVIKYGGNAMTEEKLKHGFARDVILLKLVGMNPVVVH
GGGPQIDDALKKVGKTGTFIQGMRVTDEETMEVVEWVLGGEVQQDIVMLINQYGGQAVGLTGKDGGLIRAKKLKMPDREQ
PGQFIDIGFVGDIETINPAVVRALQDDAFIPVISPIGFSDDGQAYNINADVVAGKMAEILKAEKLVMMTNIPGVMDKQGN
LLTDLSAREIDELFADGTISGGMLPKISSALDAAKSGVNSVHIIDGRIEHSLLLEILTEQAFGTMIRSH

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=288, Percent_Identity=28.4722222222222, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI145693208, Length=245, Percent_Identity=29.3877551020408, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320913, Length=268, Percent_Identity=29.4776119402985, Blast_Score=86, Evalue=7e-18,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_RALSO (Q8Y3E7)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_518154.1
- ProteinModelPortal:   Q8Y3E7
- SMR:   Q8Y3E7
- GeneID:   1218835
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc0033
- NMPDR:   fig|267608.1.peg.33
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- ProtClustDB:   PRK00942
- BioCyc:   RSOL267608:RSC0033-MONOMER
- BRENDA:   2.7.2.8
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 33099; Mature: 32968

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: BINDING 105-105 BINDING 207-207

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASVAAAPDPAGLDPELAHIAPALKAEILAQALPYIRKFHGKTIVIKYGGNAMTEEKLK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHH
HGFARDVILLKLVGMNPVVVHGGGPQIDDALKKVGKTGTFIQGMRVTDEETMEVVEWVLG
CCHHHHEEEEEEECCCEEEEECCCCCHHHHHHHHCCCCCEEECEECCCHHHHHHHHHHHC
GEVQQDIVMLINQYGGQAVGLTGKDGGLIRAKKLKMPDREQPGQFIDIGFVGDIETINPA
CCHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCHH
VVRALQDDAFIPVISPIGFSDDGQAYNINADVVAGKMAEILKAEKLVMMTNIPGVMDKQG
HHHHHCCCCCEEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCC
NLLTDLSAREIDELFADGTISGGMLPKISSALDAAKSGVNSVHIIDGRIEHSLLLEILTE
CEEECCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHH
QAFGTMIRSH
HHHHHHHHCC
>Mature Secondary Structure 
TASVAAAPDPAGLDPELAHIAPALKAEILAQALPYIRKFHGKTIVIKYGGNAMTEEKLK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHH
HGFARDVILLKLVGMNPVVVHGGGPQIDDALKKVGKTGTFIQGMRVTDEETMEVVEWVLG
CCHHHHEEEEEEECCCEEEEECCCCCHHHHHHHHCCCCCEEECEECCCHHHHHHHHHHHC
GEVQQDIVMLINQYGGQAVGLTGKDGGLIRAKKLKMPDREQPGQFIDIGFVGDIETINPA
CCHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCHH
VVRALQDDAFIPVISPIGFSDDGQAYNINADVVAGKMAEILKAEKLVMMTNIPGVMDKQG
HHHHHCCCCCEEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCC
NLLTDLSAREIDELFADGTISGGMLPKISSALDAAKSGVNSVHIIDGRIEHSLLLEILTE
CEEECCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHH
QAFGTMIRSH
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852