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The map label for this gene is yugS [H]

Identifier: 17232588

GI number: 17232588

Start: 6067654

End: 6068964

Strand: Reverse

Name: yugS [H]

Synonym: all5096

Alternate gene names: 17232588

Gene position: 6068964-6067654 (Counterclockwise)

Preceding gene: 17232589

Following gene: 17232586

Centisome position: 94.62

GC content: 44.55

Gene sequence:

>1311_bases
GTGGGGCTGCGGTTGCTATCAGTACTGCTGCTGATTGTGATTAATGCTTTTTTTGTCACAGCCGAGTTTTCCATCGTAAC
TGTTAGGCGATCGCGCATTCATCAGTTAGTTCAATCTGGGGATATTCAGGCGATCGCAGTTGAGTCACTACAGCGCAACA
TTGATCGAGTGTTATCAACAACCCAATTAGGTATCACCCTCTCTAGTTTAGCCGTGGGTTGGATTGGCGAAAGTTCCATT
GCTGTAGTCATGCGTTGGTGGATAAAATCCTGGCCATTACCCGCCAATGTGAATCATTTTGTTGCTCATTCTCTGTCAAT
TCCCATTGCCTTTTTCTTGATCGCCTATCTACAGATTGTGTTAGGTGAACTGTGTCCAAAATCAGTCGCCATGCTGTACT
CAGAACAGCTAGCGCGTTTTTTGGGGCCTGCTATAAAAGCGATCGTGCGTTTTTTCCGTCCCTTTATCTGGATTCTCAAC
CAATCCACTAGTTATCTGCTGCGGCTATTTGGCGTTGAATATACAGGTCAAAGCTGGCGACCACCAGTAACACCAGAAGA
ATTACAGTTAATTATCTCTACAGAGAGAGAATCTACTGGTTTGGAGATGGCAGAGAGGGAACTGCTTAATAACATCTTTG
AGTTTGGTGATGTCACAGCACAAGATGTGATGATTCCCCGCAATGGCATTATTGCTCTATCTAAAGATGCTAACTTCCAA
AACTTGCTCCAACAAATGACAGCCACCGGACATTCACGTTACCCCGTGATTGGCGAATCCTTAGATGACATTCGCGGTAT
TGTTTATTTTAGAGATTTAGCTAACCCCTTGGCGATCGGTAAGTTATCTCTAGAAACCCAAATTCAACCTTGGATGCGTC
CAGTGCGGTTTGTACCGGAACATACCCCCCTCAGCGAACTATTACCTATGATGCAGCAAGAAAAGCCTGCAATGGTCATA
GTAGTAGATGAATTTGGCGGTACTGTAGGACTAGTGACCATCCAAGATGTCATTGCGGAAATTATCGGCAACGCTGGCGA
AACCTCAAGCAGTGAAGACTTGCTGATTCAGATGTTAGACCAGGAAACATTTTTAGTGCAAGCCCAGGTTAACTTAGAAG
ACCTGAACGAAGTCTTGCACCTGAATTTACCCTTAACAAGACAATATCAGACCCTAGCTGGCTTCTTACTTTATCAATTG
CAAAAAATGCCCATAAAAGGCGAAATTTTCTGCTACGACAACATCGAATTTACAATAGTCTCCGTTGATGGGCCGAGGCT
GCATCAGATTCAACTGCGGCGCTTGGGTTAG

Upstream 100 bases:

>100_bases
CCAATACCCAATACCCAATCCCCAATAGCCAATCCCCAACATCATAAATTTTGCAAAAACTTTGGCGGTGAATGAATTTT
CTAATTTGAGTTTGACAGAT

Downstream 100 bases:

>100_bases
GGATCAGAGACTTTTATGAGACAGTCCCAATAAAACAAGTTTCACCGCCAAACCAGAAAAATATCTTTTCCCTACACCCT
TATACCCTTAAACCCCTACA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MGLRLLSVLLLIVINAFFVTAEFSIVTVRRSRIHQLVQSGDIQAIAVESLQRNIDRVLSTTQLGITLSSLAVGWIGESSI
AVVMRWWIKSWPLPANVNHFVAHSLSIPIAFFLIAYLQIVLGELCPKSVAMLYSEQLARFLGPAIKAIVRFFRPFIWILN
QSTSYLLRLFGVEYTGQSWRPPVTPEELQLIISTERESTGLEMAERELLNNIFEFGDVTAQDVMIPRNGIIALSKDANFQ
NLLQQMTATGHSRYPVIGESLDDIRGIVYFRDLANPLAIGKLSLETQIQPWMRPVRFVPEHTPLSELLPMMQQEKPAMVI
VVDEFGGTVGLVTIQDVIAEIIGNAGETSSSEDLLIQMLDQETFLVQAQVNLEDLNEVLHLNLPLTRQYQTLAGFLLYQL
QKMPIKGEIFCYDNIEFTIVSVDGPRLHQIQLRRLG

Sequences:

>Translated_436_residues
MGLRLLSVLLLIVINAFFVTAEFSIVTVRRSRIHQLVQSGDIQAIAVESLQRNIDRVLSTTQLGITLSSLAVGWIGESSI
AVVMRWWIKSWPLPANVNHFVAHSLSIPIAFFLIAYLQIVLGELCPKSVAMLYSEQLARFLGPAIKAIVRFFRPFIWILN
QSTSYLLRLFGVEYTGQSWRPPVTPEELQLIISTERESTGLEMAERELLNNIFEFGDVTAQDVMIPRNGIIALSKDANFQ
NLLQQMTATGHSRYPVIGESLDDIRGIVYFRDLANPLAIGKLSLETQIQPWMRPVRFVPEHTPLSELLPMMQQEKPAMVI
VVDEFGGTVGLVTIQDVIAEIIGNAGETSSSEDLLIQMLDQETFLVQAQVNLEDLNEVLHLNLPLTRQYQTLAGFLLYQL
QKMPIKGEIFCYDNIEFTIVSVDGPRLHQIQLRRLG
>Mature_435_residues
GLRLLSVLLLIVINAFFVTAEFSIVTVRRSRIHQLVQSGDIQAIAVESLQRNIDRVLSTTQLGITLSSLAVGWIGESSIA
VVMRWWIKSWPLPANVNHFVAHSLSIPIAFFLIAYLQIVLGELCPKSVAMLYSEQLARFLGPAIKAIVRFFRPFIWILNQ
STSYLLRLFGVEYTGQSWRPPVTPEELQLIISTERESTGLEMAERELLNNIFEFGDVTAQDVMIPRNGIIALSKDANFQN
LLQQMTATGHSRYPVIGESLDDIRGIVYFRDLANPLAIGKLSLETQIQPWMRPVRFVPEHTPLSELLPMMQQEKPAMVIV
VDEFGGTVGLVTIQDVIAEIIGNAGETSSSEDLLIQMLDQETFLVQAQVNLEDLNEVLHLNLPLTRQYQTLAGFLLYQLQ
KMPIKGEIFCYDNIEFTIVSVDGPRLHQIQLRRLG

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=393, Percent_Identity=29.7709923664122, Blast_Score=209, Evalue=3e-54,
Organism=Escherichia coli, GI1790664, Length=434, Percent_Identity=23.963133640553, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI145693175, Length=420, Percent_Identity=25.4761904761905, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1786879, Length=254, Percent_Identity=27.9527559055118, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI87082033, Length=241, Percent_Identity=28.6307053941909, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788119, Length=231, Percent_Identity=25.1082251082251, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 49128; Mature: 48997

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLRLLSVLLLIVINAFFVTAEFSIVTVRRSRIHQLVQSGDIQAIAVESLQRNIDRVLST
CCHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHH
TQLGITLSSLAVGWIGESSIAVVMRWWIKSWPLPANVNHFVAHSLSIPIAFFLIAYLQIV
HHHCEEHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LGELCPKSVAMLYSEQLARFLGPAIKAIVRFFRPFIWILNQSTSYLLRLFGVEYTGQSWR
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCC
PPVTPEELQLIISTERESTGLEMAERELLNNIFEFGDVTAQDVMIPRNGIIALSKDANFQ
CCCCHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHEEECCCCEEEEECCCCHH
NLLQQMTATGHSRYPVIGESLDDIRGIVYFRDLANPLAIGKLSLETQIQPWMRPVRFVPE
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHCCEEEHHHHHHHHHHHHHCCCC
HTPLSELLPMMQQEKPAMVIVVDEFGGTVGLVTIQDVIAEIIGNAGETSSSEDLLIQMLD
CCCHHHHHHHHHCCCCCEEEEEECCCCEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHC
QETFLVQAQVNLEDLNEVLHLNLPLTRQYQTLAGFLLYQLQKMPIKGEIFCYDNIEFTIV
CCEEEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEE
SVDGPRLHQIQLRRLG
ECCCCCEEHHHHCCCC
>Mature Secondary Structure 
GLRLLSVLLLIVINAFFVTAEFSIVTVRRSRIHQLVQSGDIQAIAVESLQRNIDRVLST
CHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHH
TQLGITLSSLAVGWIGESSIAVVMRWWIKSWPLPANVNHFVAHSLSIPIAFFLIAYLQIV
HHHCEEHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LGELCPKSVAMLYSEQLARFLGPAIKAIVRFFRPFIWILNQSTSYLLRLFGVEYTGQSWR
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCC
PPVTPEELQLIISTERESTGLEMAERELLNNIFEFGDVTAQDVMIPRNGIIALSKDANFQ
CCCCHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHEEECCCCEEEEECCCCHH
NLLQQMTATGHSRYPVIGESLDDIRGIVYFRDLANPLAIGKLSLETQIQPWMRPVRFVPE
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHCCEEEHHHHHHHHHHHHHCCCC
HTPLSELLPMMQQEKPAMVIVVDEFGGTVGLVTIQDVIAEIIGNAGETSSSEDLLIQMLD
CCCHHHHHHHHHCCCCCEEEEEECCCCEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHC
QETFLVQAQVNLEDLNEVLHLNLPLTRQYQTLAGFLLYQLQKMPIKGEIFCYDNIEFTIV
CCEEEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEE
SVDGPRLHQIQLRRLG
ECCCCCEEHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]