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The map label for this gene is yggV [C]

Identifier: 17232580

GI number: 17232580

Start: 6060003

End: 6060593

Strand: Reverse

Name: yggV [C]

Synonym: all5088

Alternate gene names: 17232580

Gene position: 6060593-6060003 (Counterclockwise)

Preceding gene: 17232581

Following gene: 17232577

Centisome position: 94.49

GC content: 46.02

Gene sequence:

>591_bases
ATGACTAAAATCCTCATAGTAGCTACAAGTAATGCAGGTAAGCTGCGGGAAATGCAGGCTTACCTCGCCAACACCGATTG
GGAATTAACTCTGAAGCCGACAGAATTAGAAGTGGAAGAGACAGGTGATACCTTTGCTTCTAATGCTTGTCTCAAAGCCT
CAGAGGTTGCTAAAGCTACAGGGAACTGGGCGATCGCTGATGACTCTGGTTTACAAGTGGATGCCCTCAATGGTCTTCCG
GGGGTGTATTCTGCTCGTTATGGTAAAACTGATGGGGAAAGAATTTCTCGGTTACTGAAGGAATTAGGTAGTGAAGTTAA
CCGACAAGCACAATTTGTCTGTGTAGTAGCGATCGCCTCTCCTGATGGAGCGATCGCCCTGCAAGCAGAAGGTATTTGTC
GTGGCGAAATTCTCCATGCACCCCTTGGTAGCGGTGGTTTCGGATATGACCCAATTTTTTACGTTCCCGAAAAGCAATTA
ACCTTTGCGGAGATGACACCAGAACTGAAAAAATCTGTCAGTCATCGCGGTAAAGCTTTTGCGGCTTTACTTCCTAAAAT
GGCAGCTATGCTGAGTTCAAGTGCTGAATAA

Upstream 100 bases:

>100_bases
TTGGGCAAAACACTGGGCAGAGTAAAATTTAGTTAATAGTCAATAGTTCAAAGGTGTTTTGACTGTTGACTGTTGACTGT
TAACTGTTGACCGTTGACTA

Downstream 100 bases:

>100_bases
AAATAGACTTACCATAGTGGGGTGGTAAGTCTAAAATCATCGAATAGGAAATGTTTGTGATTACTTTTTAGCAATGAATA
GACTATCAATCTAACGCCCA

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MTKILIVATSNAGKLREMQAYLANTDWELTLKPTELEVEETGDTFASNACLKASEVAKATGNWAIADDSGLQVDALNGLP
GVYSARYGKTDGERISRLLKELGSEVNRQAQFVCVVAIASPDGAIALQAEGICRGEILHAPLGSGGFGYDPIFYVPEKQL
TFAEMTPELKKSVSHRGKAFAALLPKMAAMLSSSAE

Sequences:

>Translated_196_residues
MTKILIVATSNAGKLREMQAYLANTDWELTLKPTELEVEETGDTFASNACLKASEVAKATGNWAIADDSGLQVDALNGLP
GVYSARYGKTDGERISRLLKELGSEVNRQAQFVCVVAIASPDGAIALQAEGICRGEILHAPLGSGGFGYDPIFYVPEKQL
TFAEMTPELKKSVSHRGKAFAALLPKMAAMLSSSAE
>Mature_195_residues
TKILIVATSNAGKLREMQAYLANTDWELTLKPTELEVEETGDTFASNACLKASEVAKATGNWAIADDSGLQVDALNGLPG
VYSARYGKTDGERISRLLKELGSEVNRQAQFVCVVAIASPDGAIALQAEGICRGEILHAPLGSGGFGYDPIFYVPEKQLT
FAEMTPELKKSVSHRGKAFAALLPKMAAMLSSSAE

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Escherichia coli, GI1789324, Length=193, Percent_Identity=45.0777202072539, Blast_Score=139, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17556833, Length=184, Percent_Identity=30.9782608695652, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322529, Length=187, Percent_Identity=33.1550802139037, Blast_Score=86, Evalue=5e-18,
Organism=Drosophila melanogaster, GI19920712, Length=184, Percent_Identity=32.0652173913043, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_NOSS1 (Q8YM52)

Other databases:

- EMBL:   BA000019
- PIR:   AH2441
- RefSeq:   NP_489128.1
- ProteinModelPortal:   Q8YM52
- SMR:   Q8YM52
- STRING:   Q8YM52
- GeneID:   1108692
- GenomeReviews:   BA000019_GR
- KEGG:   ana:all5088
- NMPDR:   fig|103690.1.peg.5395
- eggNOG:   COG0127
- HOGENOM:   HBG697237
- OMA:   TGVTFAE
- PhylomeDB:   Q8YM52
- ProtClustDB:   PRK00120
- BioCyc:   NSP103690:ALL5088-MONOMER
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 20883; Mature: 20752

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKILIVATSNAGKLREMQAYLANTDWELTLKPTELEVEETGDTFASNACLKASEVAKAT
CCEEEEEEECCCCHHHHHHHHHCCCCCEEEECCCEEEEECCCCCHHCCCCCCHHHHHHCC
GNWAIADDSGLQVDALNGLPGVYSARYGKTDGERISRLLKELGSEVNRQAQFVCVVAIAS
CCEEEECCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEC
PDGAIALQAEGICRGEILHAPLGSGGFGYDPIFYVPEKQLTFAEMTPELKKSVSHRGKAF
CCCEEEEEECCCCCCEEEECCCCCCCCCCCCEEEECCCCEEHHHCCHHHHHHHHHCCHHH
AALLPKMAAMLSSSAE
HHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKILIVATSNAGKLREMQAYLANTDWELTLKPTELEVEETGDTFASNACLKASEVAKAT
CEEEEEEECCCCHHHHHHHHHCCCCCEEEECCCEEEEECCCCCHHCCCCCCHHHHHHCC
GNWAIADDSGLQVDALNGLPGVYSARYGKTDGERISRLLKELGSEVNRQAQFVCVVAIAS
CCEEEECCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEC
PDGAIALQAEGICRGEILHAPLGSGGFGYDPIFYVPEKQLTFAEMTPELKKSVSHRGKAF
CCCEEEEEECCCCCCEEEECCCCCCCCCCCCEEEECCCCEEHHHCCHHHHHHHHHCCHHH
AALLPKMAAMLSSSAE
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840