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The map label for this gene is pkn1 [H]

Identifier: 17232508

GI number: 17232508

Start: 5988219

End: 5989040

Strand: Reverse

Name: pkn1 [H]

Synonym: all5016

Alternate gene names: 17232508

Gene position: 5989040-5988219 (Counterclockwise)

Preceding gene: 17232509

Following gene: 17232507

Centisome position: 93.38

GC content: 46.72

Gene sequence:

>822_bases
GTGAATGTGGACGCTCAAGGAAAAATTATTGAGCGCAGTCAGGGAAGTGCAGAATTTTTTGCAGAAGACTTGGGTAATGG
TGTAACGCTAGAGATGGTGTCCATTCCCGGCGGTAAATTCCTCATGGGTTCGCCAGACAATGAAGAAGGACGAGATGATT
CTGAAAGTCCACAGCACAACGTCACCATTCAACCCTTTTTCATGGGGAAATTTCCCGTAACCCAAGCTCAATGGGCAGCC
GTTGCCGCTTTTGATAAAGTAAATATTGATTTAAAATCTGACCCATCTCGCTTTAAAGGTGCTAATCGTCCCGTTGAGCG
TATTTCCTGGGATGATGCGGTTGAATTTTGCACCAGACTATCTAAAAAGACTGGTCAGATATATCGCTTACCCAGTGAAG
CCGAATGGGAATATGCTTGTCGCGGGGGAACGACTACACCGTTTTATTGTGGCGCAACGATTACAACTGAGTTGGCGAAT
TATGACGGAAATCACACCTATGGTTCTTCTCCCAGGGGTGAATATCGAGGACAAACAACCAATGTGGGAGAATTTCCTGC
TAACCCCTTTGGTTTATTTGATATGTGTGGTAATATATGGGAATGGTGTCAGGATGAGTGGCAGGAAAATTATAATAATG
CACCAACTGATGGTAGTGCATGGCTAATTAATAATGATAATCAGCGACGTCTGCTGCGTGGTGGTTCGTGGAACTACTAT
CCCAGGGGTTGCCGTTCGTTGAGTCGCCTCAGTAACACGCGCGACGACAGGAACGAGCGCGTGGGTTGTCGGGTTGTGGT
TGTGCGGGGCAGGCTTTCTTAG

Upstream 100 bases:

>100_bases
AGATGAAGATGTTGCACCTATAGAAGAACGGATTCTTGGTAAACAGAAACCGCCTGTATCTGAAGAACCCCTTAAAGCCA
AGAAATTTGAGTTTGAAACT

Downstream 100 bases:

>100_bases
CACTTTACTCTCTTGCCCTTTAGCACTCTGCACTTTTTTCTTTACCATTCTTAAGGTTTCGCGCTCTGCGCGCTCAAATT
TTTTGAGATTTCTTGGATGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MNVDAQGKIIERSQGSAEFFAEDLGNGVTLEMVSIPGGKFLMGSPDNEEGRDDSESPQHNVTIQPFFMGKFPVTQAQWAA
VAAFDKVNIDLKSDPSRFKGANRPVERISWDDAVEFCTRLSKKTGQIYRLPSEAEWEYACRGGTTTPFYCGATITTELAN
YDGNHTYGSSPRGEYRGQTTNVGEFPANPFGLFDMCGNIWEWCQDEWQENYNNAPTDGSAWLINNDNQRRLLRGGSWNYY
PRGCRSLSRLSNTRDDRNERVGCRVVVVRGRLS

Sequences:

>Translated_273_residues
MNVDAQGKIIERSQGSAEFFAEDLGNGVTLEMVSIPGGKFLMGSPDNEEGRDDSESPQHNVTIQPFFMGKFPVTQAQWAA
VAAFDKVNIDLKSDPSRFKGANRPVERISWDDAVEFCTRLSKKTGQIYRLPSEAEWEYACRGGTTTPFYCGATITTELAN
YDGNHTYGSSPRGEYRGQTTNVGEFPANPFGLFDMCGNIWEWCQDEWQENYNNAPTDGSAWLINNDNQRRLLRGGSWNYY
PRGCRSLSRLSNTRDDRNERVGCRVVVVRGRLS
>Mature_273_residues
MNVDAQGKIIERSQGSAEFFAEDLGNGVTLEMVSIPGGKFLMGSPDNEEGRDDSESPQHNVTIQPFFMGKFPVTQAQWAA
VAAFDKVNIDLKSDPSRFKGANRPVERISWDDAVEFCTRLSKKTGQIYRLPSEAEWEYACRGGTTTPFYCGATITTELAN
YDGNHTYGSSPRGEYRGQTTNVGEFPANPFGLFDMCGNIWEWCQDEWQENYNNAPTDGSAWLINNDNQRRLLRGGSWNYY
PRGCRSLSRLSNTRDDRNERVGCRVVVVRGRLS

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=265, Percent_Identity=30.188679245283, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI194248087, Length=286, Percent_Identity=30.4195804195804, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI194248088, Length=301, Percent_Identity=28.9036544850498, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI38202250, Length=290, Percent_Identity=28.2758620689655, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI257470977, Length=230, Percent_Identity=29.5652173913043, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI226437577, Length=177, Percent_Identity=31.0734463276836, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI20130397, Length=307, Percent_Identity=26.7100977198697, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 30688; Mature: 30688

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVDAQGKIIERSQGSAEFFAEDLGNGVTLEMVSIPGGKFLMGSPDNEEGRDDSESPQHN
CCCCCCCCEEECCCCCHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCCCCCCCCCCCCC
VTIQPFFMGKFPVTQAQWAAVAAFDKVNIDLKSDPSRFKGANRPVERISWDDAVEFCTRL
EEEEEEECCCCCCCHHHHHHHEEHEEEEEEECCCHHHHCCCCCCHHHCCHHHHHHHHHHH
SKKTGQIYRLPSEAEWEYACRGGTTTPFYCGATITTELANYDGNHTYGSSPRGEYRGQTT
HHHCCCEEECCCCCCCEEEECCCCCCCEEECCCCEEHHHCCCCCCCCCCCCCCCCCCCCC
NVGEFPANPFGLFDMCGNIWEWCQDEWQENYNNAPTDGSAWLINNDNQRRLLRGGSWNYY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEHEECCCCCCC
PRGCRSLSRLSNTRDDRNERVGCRVVVVRGRLS
CHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MNVDAQGKIIERSQGSAEFFAEDLGNGVTLEMVSIPGGKFLMGSPDNEEGRDDSESPQHN
CCCCCCCCEEECCCCCHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCCCCCCCCCCCCC
VTIQPFFMGKFPVTQAQWAAVAAFDKVNIDLKSDPSRFKGANRPVERISWDDAVEFCTRL
EEEEEEECCCCCCCHHHHHHHEEHEEEEEEECCCHHHHCCCCCCHHHCCHHHHHHHHHHH
SKKTGQIYRLPSEAEWEYACRGGTTTPFYCGATITTELANYDGNHTYGSSPRGEYRGQTT
HHHCCCEEECCCCCCCEEEECCCCCCCEEECCCCEEHHHCCCCCCCCCCCCCCCCCCCCC
NVGEFPANPFGLFDMCGNIWEWCQDEWQENYNNAPTDGSAWLINNDNQRRLLRGGSWNYY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEHEECCCCCCC
PRGCRSLSRLSNTRDDRNERVGCRVVVVRGRLS
CHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]