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The map label for this gene is 17232462

Identifier: 17232462

GI number: 17232462

Start: 5933239

End: 5935335

Strand: Reverse

Name: 17232462

Synonym: all4970

Alternate gene names: NA

Gene position: 5935335-5933239 (Counterclockwise)

Preceding gene: 17232463

Following gene: 17232461

Centisome position: 92.54

GC content: 39.1

Gene sequence:

>2097_bases
ATGTTAAAAGTATTCGCTGACCGGGGTGGTACATTCACAGATATTGTTGCTGTTACCCATAATCAAGAGATCATAGAGAG
ATTATCAAAGTCAACCGAACGTTTTCTGATTGTTCCTCTGCCTAATCAAGAATGGATAATAGTATATAAATTACTCTCCG
AAAATCCTGAACAATATCAAGATGCAGTTATCCAAGGTATTCGAGATATCATTGGGCTGTCACGGAATGAACCCATTTCT
GATGAAGCAATAGAAGTAGTCAAAATGGGAACAACAGTAGCTACAAATGCTCTGTTGGAAAGAAAAGGAGATAGGGTTGT
CCTACTGATTACCACAGGATTTAAAGATGCGTTAAGAATTGGCTATCAAAATCGTCCGAACATTTTTGCACAGCGAATTG
TTTTACCGACAATGCTTTATGAACAGGTAATTGAAGTAGAAGAACGCTATGATGCCCAAGGAAATGAATTAACACCTGTC
AACATTGCCCAGGTCAAAGAAGATTTACAAGCAGTTTACCATACAGGCATTCGTAGCTGTGCCATTATTTTGATGCACAG
CGATCGCTACCCCATTCATGAACAACAAGTAGCCCAAATCGCCCAGGAAATTGGCTTTACTCAAATCTCCATTTCCCACC
AAGTTAGTCCCTTAATGAAGTTAGTAAGCCGAGGAGATACAACAGTAGTAGATGCTTATTTAACTCCGATTTTACGGCGC
TATGTCAACCAAGTATCTCATCAGTTGCCTAATATCAGATTAATGTTCATGAAATCTGATGGCGGTTTAACGGATGCTGA
TAAATTTCAGGGAAAAGATAGTATTTTAAGCGGCCCGGCTGGCGGTATAGTTGGCGCAGTTCAAACTAGTAAAAGAGCAG
GCTTTGAGTTAGTAATTACCTTTGATATGGGTGGTACAAGTACAGATGTTGCCCATTTTAAAGGTGAGTATGAACGTCAA
TTAGATTCGGAAATAGCTGGTGCGCGGATGCGAGTTCCCGTATTAGCAATTAACACTATTGCGGCTGGTGGCGGTTCAAT
TTTATTCTTTGATGGTTCTAGTTATCGTGTCGGCCCAGAATCGGCTGGTTCAAATCCTGGGCCTGCTTGTTATCGGCGTG
GTGGACTTTTGGCTGTCACAGATGCCAATGTGATGTTAGGTAAAATTCACCCCCAATATTTCCCTTCTGTGTTTGGGACT
GATGGCAATTTACCTTTAGATAAAGATATTGTCATTCAGAAATTTACTCAACTAGCCCAACATATTGCAGATGTCACAGG
AAATTATCGTACACCCGAACAAGTAGCGGCTGGATTTATTGCCATCGCAGTAGAAAATATGGCAAATGCGATTAAGAAAA
TCAGTCTCCAACGCGGTTATGATGTCAGCGATTATGTACTTTGTTGTTTCGGTGGCGCAGGCGCACAAGTTGCTTGTTTA
ATTGCCGATACATTAGGCATGAAAAAGATATTTCTTCATCCTTATGCTGGGGTTCTTTCTGCTTATGGTATGGGATTAGC
TGATGTCCGTGCTACTAGAGTCGCCGGAGTAGAACAATTTCTAACTGAAGCATTAATTCCTCAATTATTACAGTTAATGG
AGTTTTTAAAAACCCAAGCCAGAAGTGAATTTAGTAATATTGAAACAATTAATAATGAGATAGTAGTAAGAAAAGTAAAT
TTAAAATATGCAGGAACTAACTCTACTTTAACAGTTGACTTTTCCTCAGATGTGACAACGATGAAACAAGAATTTGAAAT
AGAACATAAATCTCGTTATGGTTTCATCCAGTCAGCGAAAAATTTAATTGTTGAATCTATCTCAGTAGAAGTGATTCAAC
AAATGAATACTCCCGAAGAACCGTTAATTATCCGTAACCCTTCCATAGAGGAAATACCCAAATCTGTTGAAATAGTACAA
ATGTTTACAGCAGATAAATGGCATAATACACCCGTTTACCGTCGAGAAGACTTACAACCGGAAGATAGTATTAACGGCCC
TGCCATCATCATTGAAAAAATCAGTACGATTGTAGTTGAGCCTAATTGGCAGGCAAGATTAACTGAACGCAATCATTTGA
TTTTACAACGGGTTTAA

Upstream 100 bases:

>100_bases
CTAATTTAGGGTTATGTACTATAAACCATCAAAAACAGCATAAAGACTTCTCTTTTACACACCTCATGGTTATCATACAC
ATATCCGTATAAATAGGGAA

Downstream 100 bases:

>100_bases
ACAAGAGATTAGAGTCTAGAAACTGATATTTTTGACTCAGCATTCGTTACTTTCTTGGAAACTGCTAGTTTTAAAAACTA
AAATTTGACAATATTTTTGG

Product: hypothetical protein

Products: ADP; phosphate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 698; Mature: 698

Protein sequence:

>698_residues
MLKVFADRGGTFTDIVAVTHNQEIIERLSKSTERFLIVPLPNQEWIIVYKLLSENPEQYQDAVIQGIRDIIGLSRNEPIS
DEAIEVVKMGTTVATNALLERKGDRVVLLITTGFKDALRIGYQNRPNIFAQRIVLPTMLYEQVIEVEERYDAQGNELTPV
NIAQVKEDLQAVYHTGIRSCAIILMHSDRYPIHEQQVAQIAQEIGFTQISISHQVSPLMKLVSRGDTTVVDAYLTPILRR
YVNQVSHQLPNIRLMFMKSDGGLTDADKFQGKDSILSGPAGGIVGAVQTSKRAGFELVITFDMGGTSTDVAHFKGEYERQ
LDSEIAGARMRVPVLAINTIAAGGGSILFFDGSSYRVGPESAGSNPGPACYRRGGLLAVTDANVMLGKIHPQYFPSVFGT
DGNLPLDKDIVIQKFTQLAQHIADVTGNYRTPEQVAAGFIAIAVENMANAIKKISLQRGYDVSDYVLCCFGGAGAQVACL
IADTLGMKKIFLHPYAGVLSAYGMGLADVRATRVAGVEQFLTEALIPQLLQLMEFLKTQARSEFSNIETINNEIVVRKVN
LKYAGTNSTLTVDFSSDVTTMKQEFEIEHKSRYGFIQSAKNLIVESISVEVIQQMNTPEEPLIIRNPSIEEIPKSVEIVQ
MFTADKWHNTPVYRREDLQPEDSINGPAIIIEKISTIVVEPNWQARLTERNHLILQRV

Sequences:

>Translated_698_residues
MLKVFADRGGTFTDIVAVTHNQEIIERLSKSTERFLIVPLPNQEWIIVYKLLSENPEQYQDAVIQGIRDIIGLSRNEPIS
DEAIEVVKMGTTVATNALLERKGDRVVLLITTGFKDALRIGYQNRPNIFAQRIVLPTMLYEQVIEVEERYDAQGNELTPV
NIAQVKEDLQAVYHTGIRSCAIILMHSDRYPIHEQQVAQIAQEIGFTQISISHQVSPLMKLVSRGDTTVVDAYLTPILRR
YVNQVSHQLPNIRLMFMKSDGGLTDADKFQGKDSILSGPAGGIVGAVQTSKRAGFELVITFDMGGTSTDVAHFKGEYERQ
LDSEIAGARMRVPVLAINTIAAGGGSILFFDGSSYRVGPESAGSNPGPACYRRGGLLAVTDANVMLGKIHPQYFPSVFGT
DGNLPLDKDIVIQKFTQLAQHIADVTGNYRTPEQVAAGFIAIAVENMANAIKKISLQRGYDVSDYVLCCFGGAGAQVACL
IADTLGMKKIFLHPYAGVLSAYGMGLADVRATRVAGVEQFLTEALIPQLLQLMEFLKTQARSEFSNIETINNEIVVRKVN
LKYAGTNSTLTVDFSSDVTTMKQEFEIEHKSRYGFIQSAKNLIVESISVEVIQQMNTPEEPLIIRNPSIEEIPKSVEIVQ
MFTADKWHNTPVYRREDLQPEDSINGPAIIIEKISTIVVEPNWQARLTERNHLILQRV
>Mature_698_residues
MLKVFADRGGTFTDIVAVTHNQEIIERLSKSTERFLIVPLPNQEWIIVYKLLSENPEQYQDAVIQGIRDIIGLSRNEPIS
DEAIEVVKMGTTVATNALLERKGDRVVLLITTGFKDALRIGYQNRPNIFAQRIVLPTMLYEQVIEVEERYDAQGNELTPV
NIAQVKEDLQAVYHTGIRSCAIILMHSDRYPIHEQQVAQIAQEIGFTQISISHQVSPLMKLVSRGDTTVVDAYLTPILRR
YVNQVSHQLPNIRLMFMKSDGGLTDADKFQGKDSILSGPAGGIVGAVQTSKRAGFELVITFDMGGTSTDVAHFKGEYERQ
LDSEIAGARMRVPVLAINTIAAGGGSILFFDGSSYRVGPESAGSNPGPACYRRGGLLAVTDANVMLGKIHPQYFPSVFGT
DGNLPLDKDIVIQKFTQLAQHIADVTGNYRTPEQVAAGFIAIAVENMANAIKKISLQRGYDVSDYVLCCFGGAGAQVACL
IADTLGMKKIFLHPYAGVLSAYGMGLADVRATRVAGVEQFLTEALIPQLLQLMEFLKTQARSEFSNIETINNEIVVRKVN
LKYAGTNSTLTVDFSSDVTTMKQEFEIEHKSRYGFIQSAKNLIVESISVEVIQQMNTPEEPLIIRNPSIEEIPKSVEIVQ
MFTADKWHNTPVYRREDLQPEDSINGPAIIIEKISTIVVEPNWQARLTERNHLILQRV

Specific function: Unknown

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=734, Percent_Identity=37.3297002724796, Blast_Score=441, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI133901900, Length=406, Percent_Identity=42.3645320197044, Blast_Score=286, Evalue=3e-77,
Organism=Saccharomyces cerevisiae, GI6322634, Length=743, Percent_Identity=34.7240915208614, Blast_Score=416, Evalue=1e-117,
Organism=Drosophila melanogaster, GI45550492, Length=746, Percent_Identity=38.6058981233244, Blast_Score=473, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: 3.5.2.9

Molecular weight: Translated: 77302; Mature: 77302

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKVFADRGGTFTDIVAVTHNQEIIERLSKSTERFLIVPLPNQEWIIVYKLLSENPEQYQ
CEEEEECCCCCEEEEEEEECCHHHHHHHHCCCCCEEEEECCCCCEEEEEEECCCCHHHHH
DAVIQGIRDIIGLSRNEPISDEAIEVVKMGTTVATNALLERKGDRVVLLITTGFKDALRI
HHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHC
GYQNRPNIFAQRIVLPTMLYEQVIEVEERYDAQGNELTPVNIAQVKEDLQAVYHTGIRSC
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCE
AIILMHSDRYPIHEQQVAQIAQEIGFTQISISHQVSPLMKLVSRGDTTVVDAYLTPILRR
EEEEEECCCCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHCCCCEEHHHHHHHHHHH
YVNQVSHQLPNIRLMFMKSDGGLTDADKFQGKDSILSGPAGGIVGAVQTSKRAGFELVIT
HHHHHHHHCCCEEEEEEECCCCCCCHHHHCCCCCCCCCCCCCEEEEEECCCCCCEEEEEE
FDMGGTSTDVAHFKGEYERQLDSEIAGARMRVPVLAINTIAAGGGSILFFDGSSYRVGPE
EECCCCCCCHHHHCCHHHHHHHHHHCCCEEEEEEEEEEEEECCCCEEEEECCCCEEECCC
SAGSNPGPACYRRGGLLAVTDANVMLGKIHPQYFPSVFGTDGNLPLDKDIVIQKFTQLAQ
CCCCCCCCHHHHCCCEEEEECCCEEEECCCHHHCCHHCCCCCCCCCCHHHHHHHHHHHHH
HIADVTGNYRTPEQVAAGFIAIAVENMANAIKKISLQRGYDVSDYVLCCFGGAGAQVACL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEE
IADTLGMKKIFLHPYAGVLSAYGMGLADVRATRVAGVEQFLTEALIPQLLQLMEFLKTQA
EHHHCCCHHEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSEFSNIETINNEIVVRKVNLKYAGTNSTLTVDFSSDVTTMKQEFEIEHKSRYGFIQSAK
HHHHHHHHHCCCEEEEEEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHH
NLIVESISVEVIQQMNTPEEPLIIRNPSIEEIPKSVEIVQMFTADKWHNTPVYRREDLQP
HHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCC
EDSINGPAIIIEKISTIVVEPNWQARLTERNHLILQRV
CCCCCCCEEEEEECEEEEECCCCCEEECCCCCEEEECC
>Mature Secondary Structure
MLKVFADRGGTFTDIVAVTHNQEIIERLSKSTERFLIVPLPNQEWIIVYKLLSENPEQYQ
CEEEEECCCCCEEEEEEEECCHHHHHHHHCCCCCEEEEECCCCCEEEEEEECCCCHHHHH
DAVIQGIRDIIGLSRNEPISDEAIEVVKMGTTVATNALLERKGDRVVLLITTGFKDALRI
HHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHC
GYQNRPNIFAQRIVLPTMLYEQVIEVEERYDAQGNELTPVNIAQVKEDLQAVYHTGIRSC
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCE
AIILMHSDRYPIHEQQVAQIAQEIGFTQISISHQVSPLMKLVSRGDTTVVDAYLTPILRR
EEEEEECCCCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHCCCCEEHHHHHHHHHHH
YVNQVSHQLPNIRLMFMKSDGGLTDADKFQGKDSILSGPAGGIVGAVQTSKRAGFELVIT
HHHHHHHHCCCEEEEEEECCCCCCCHHHHCCCCCCCCCCCCCEEEEEECCCCCCEEEEEE
FDMGGTSTDVAHFKGEYERQLDSEIAGARMRVPVLAINTIAAGGGSILFFDGSSYRVGPE
EECCCCCCCHHHHCCHHHHHHHHHHCCCEEEEEEEEEEEEECCCCEEEEECCCCEEECCC
SAGSNPGPACYRRGGLLAVTDANVMLGKIHPQYFPSVFGTDGNLPLDKDIVIQKFTQLAQ
CCCCCCCCHHHHCCCEEEEECCCEEEECCCHHHCCHHCCCCCCCCCCHHHHHHHHHHHHH
HIADVTGNYRTPEQVAAGFIAIAVENMANAIKKISLQRGYDVSDYVLCCFGGAGAQVACL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEE
IADTLGMKKIFLHPYAGVLSAYGMGLADVRATRVAGVEQFLTEALIPQLLQLMEFLKTQA
EHHHCCCHHEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSEFSNIETINNEIVVRKVNLKYAGTNSTLTVDFSSDVTTMKQEFEIEHKSRYGFIQSAK
HHHHHHHHHCCCEEEEEEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHH
NLIVESISVEVIQQMNTPEEPLIIRNPSIEEIPKSVEIVQMFTADKWHNTPVYRREDLQP
HHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCC
EDSINGPAIIIEKISTIVVEPNWQARLTERNHLILQRV
CCCCCCCEEEEEECEEEEECCCCCEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 5-oxo-L-proline; H2O

Specific reaction: ATP + 5-oxo-L-proline + 2 H2O = ADP + phosphate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]