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The map label for this gene is speA [H]

Identifier: 17232379

GI number: 17232379

Start: 5823472

End: 5824938

Strand: Reverse

Name: speA [H]

Synonym: all4887

Alternate gene names: 17232379

Gene position: 5824938-5823472 (Counterclockwise)

Preceding gene: 17232381

Following gene: 17232378

Centisome position: 90.82

GC content: 44.51

Gene sequence:

>1467_bases
ATGCTTGATCAAAACCAAACACCACTAATAGAATCTATAAAAGCTTGTACTGCTCGACATCATGCAGCGTTTTATACTCC
TGGGCATAAGCAGGGGAGGGGGATTGCTCAACCTTTGGCTGATTTGTTGGGTAAAGCGGTATTTAGTGCTGATTTGACGG
AGTTGGCTGATTTAGATAATTTATCTGCGCCCCAAGGAGTGATTCAGGAAGCCCAACAATTAGCGGCGGCGGCGTTTGGT
GCCTCACAGACATGGTTTTTGGTCAATGGTTCTACTTGCGGTGTCGAGGCGGCAATTCTGGCTACTTGTAGACCGGGGGA
TAAAATTATTTTGCCTCGGAATGTACATTCATCGGCGATCGCTGGTTTAATTCTCTCTGGTGCTATCCCGATTTTTATTT
ATCCTGAATATGACCCAGTTTTAGATATCGCCCATAGCATCACGCCTGAGGCTGTAAAAGCAGCTTTGCAACAACATCCT
GATGCTAAAGCGGTGTTGACAGTTTACCCTACATATTACGGTGTATGTGGGGATTTAGAGGCGATCGCCCAAGTCACCCA
CCACTACAATATTCCTTTACTAGTAGATGAAGCCCACGGCGCACACTTCGCTTTTCACCCAGAATTACCCACCTCGGCCT
TAGCCGCAGGTGCAGATTTAACTGTACAGTCGATTCACAAGGTACTGGGTGCAATGACGCAAGCTTCAATGCTTCACATC
CAAGGTGACAGAATAAATGCGGTTCGAGTTAGTCAGGCTTTGCAGCTGCTACAGTCTACTAGCCCCAGTTATGTACTTCT
AGCTTCCCTGGATGCGGCTCGTCAACAAATGGCTTTGTCTGGTAAACAGTTAATGTCCCGTACCTTACAACTAGCGAATG
AAGCCAGAGAAAGAATTAGTCAAATTCCTGGCTTATCAGTTTTACAGCCTCCTACCAAGACACCATCACCAGGGTTTACA
ACTTTGGATAAAACACGCTTAACTGTGACTGTTTCCGGCTTGGGTTTAACGGGTTTTGCGGCGGAAGAAATTTTAGATGA
ACAACTGGGGGTAACGGCTGAATTTGCTACGTTGCAACATCTCACCTTTATTATTAGCTTGGGAAACACAGCTACTGATA
TTGAGCAGTTAGTCCAAGGTTTCACAACTTTAGCAGAAACAACACTGCCTACTAAGGCATTAGTCAACCCAAAAGTTAAT
AGTAATCTGGAATATTTTTCAGAAATTTCTCCCCGTGATGCCTTTTTTGCCGATAGTGAAACGTTATCCATCGAACAGGC
GTGCGATGGCATTTGTGCAGAAATTGTCTGTCCTTATCCCCCAGGAATCCCCGTCCTTATGCCAGGAGAAGTTATCACAA
AACCCGCCATTGAATATTTGCAACATATCCAAAGTTTAGGCGGATTCATTACTGGTTGTGCCGATACTAGTCTGAATACT
TTAAAAGTTTTAGTCAATAGTCATTAG

Upstream 100 bases:

>100_bases
TTCTCACTCTACCAAGATTGGTCATTGGTCAGTTGTCAGTTGTCAGTTGTTAGTAGTTTTCTAATTCCCCTGCTTCTTCC
TGCTCCCAACCTCCTTACCA

Downstream 100 bases:

>100_bases
TTTTACACCTCCATACACTCTTCCCAGTTGCTTGTATTGCTCGAAAGTCTTCATCTTAATTCACGTAATTTGCTATTAAT
TTTCTGTAAGTTAAATAGTC

Product: lysine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MLDQNQTPLIESIKACTARHHAAFYTPGHKQGRGIAQPLADLLGKAVFSADLTELADLDNLSAPQGVIQEAQQLAAAAFG
ASQTWFLVNGSTCGVEAAILATCRPGDKIILPRNVHSSAIAGLILSGAIPIFIYPEYDPVLDIAHSITPEAVKAALQQHP
DAKAVLTVYPTYYGVCGDLEAIAQVTHHYNIPLLVDEAHGAHFAFHPELPTSALAAGADLTVQSIHKVLGAMTQASMLHI
QGDRINAVRVSQALQLLQSTSPSYVLLASLDAARQQMALSGKQLMSRTLQLANEARERISQIPGLSVLQPPTKTPSPGFT
TLDKTRLTVTVSGLGLTGFAAEEILDEQLGVTAEFATLQHLTFIISLGNTATDIEQLVQGFTTLAETTLPTKALVNPKVN
SNLEYFSEISPRDAFFADSETLSIEQACDGICAEIVCPYPPGIPVLMPGEVITKPAIEYLQHIQSLGGFITGCADTSLNT
LKVLVNSH

Sequences:

>Translated_488_residues
MLDQNQTPLIESIKACTARHHAAFYTPGHKQGRGIAQPLADLLGKAVFSADLTELADLDNLSAPQGVIQEAQQLAAAAFG
ASQTWFLVNGSTCGVEAAILATCRPGDKIILPRNVHSSAIAGLILSGAIPIFIYPEYDPVLDIAHSITPEAVKAALQQHP
DAKAVLTVYPTYYGVCGDLEAIAQVTHHYNIPLLVDEAHGAHFAFHPELPTSALAAGADLTVQSIHKVLGAMTQASMLHI
QGDRINAVRVSQALQLLQSTSPSYVLLASLDAARQQMALSGKQLMSRTLQLANEARERISQIPGLSVLQPPTKTPSPGFT
TLDKTRLTVTVSGLGLTGFAAEEILDEQLGVTAEFATLQHLTFIISLGNTATDIEQLVQGFTTLAETTLPTKALVNPKVN
SNLEYFSEISPRDAFFADSETLSIEQACDGICAEIVCPYPPGIPVLMPGEVITKPAIEYLQHIQSLGGFITGCADTSLNT
LKVLVNSH
>Mature_488_residues
MLDQNQTPLIESIKACTARHHAAFYTPGHKQGRGIAQPLADLLGKAVFSADLTELADLDNLSAPQGVIQEAQQLAAAAFG
ASQTWFLVNGSTCGVEAAILATCRPGDKIILPRNVHSSAIAGLILSGAIPIFIYPEYDPVLDIAHSITPEAVKAALQQHP
DAKAVLTVYPTYYGVCGDLEAIAQVTHHYNIPLLVDEAHGAHFAFHPELPTSALAAGADLTVQSIHKVLGAMTQASMLHI
QGDRINAVRVSQALQLLQSTSPSYVLLASLDAARQQMALSGKQLMSRTLQLANEARERISQIPGLSVLQPPTKTPSPGFT
TLDKTRLTVTVSGLGLTGFAAEEILDEQLGVTAEFATLQHLTFIISLGNTATDIEQLVQGFTTLAETTLPTKALVNPKVN
SNLEYFSEISPRDAFFADSETLSIEQACDGICAEIVCPYPPGIPVLMPGEVITKPAIEYLQHIQSLGGFITGCADTSLNT
LKVLVNSH

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1786384, Length=568, Percent_Identity=23.943661971831, Blast_Score=135, Evalue=9e-33,
Organism=Escherichia coli, GI1790573, Length=567, Percent_Identity=23.2804232804233, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI221142684, Length=589, Percent_Identity=23.7691001697793, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI87082193, Length=317, Percent_Identity=27.7602523659306, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1786909, Length=332, Percent_Identity=26.5060240963855, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 51933; Mature: 51933

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDQNQTPLIESIKACTARHHAAFYTPGHKQGRGIAQPLADLLGKAVFSADLTELADLDN
CCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
LSAPQGVIQEAQQLAAAAFGASQTWFLVNGSTCGVEAAILATCRPGDKIILPRNVHSSAI
CCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEECCCCCHHHH
AGLILSGAIPIFIYPEYDPVLDIAHSITPEAVKAALQQHPDAKAVLTVYPTYYGVCGDLE
HHHHHHCCCEEEEECCCCHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCHHCCCCCHH
AIAQVTHHYNIPLLVDEAHGAHFAFHPELPTSALAAGADLTVQSIHKVLGAMTQASMLHI
HHHHHHHCCCCCEEEECCCCCEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHEEEE
QGDRINAVRVSQALQLLQSTSPSYVLLASLDAARQQMALSGKQLMSRTLQLANEARERIS
ECCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIPGLSVLQPPTKTPSPGFTTLDKTRLTVTVSGLGLTGFAAEEILDEQLGVTAEFATLQH
HCCCCCEECCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHH
LTFIISLGNTATDIEQLVQGFTTLAETTLPTKALVNPKVNSNLEYFSEISPRDAFFADSE
HHEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHCCCCCCCEECCCC
TLSIEQACDGICAEIVCPYPPGIPVLMPGEVITKPAIEYLQHIQSLGGFITGCADTSLNT
CEEHHHHHCHHHHHEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCE
LKVLVNSH
EEEEECCC
>Mature Secondary Structure
MLDQNQTPLIESIKACTARHHAAFYTPGHKQGRGIAQPLADLLGKAVFSADLTELADLDN
CCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
LSAPQGVIQEAQQLAAAAFGASQTWFLVNGSTCGVEAAILATCRPGDKIILPRNVHSSAI
CCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEECCCCCHHHH
AGLILSGAIPIFIYPEYDPVLDIAHSITPEAVKAALQQHPDAKAVLTVYPTYYGVCGDLE
HHHHHHCCCEEEEECCCCHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCHHCCCCCHH
AIAQVTHHYNIPLLVDEAHGAHFAFHPELPTSALAAGADLTVQSIHKVLGAMTQASMLHI
HHHHHHHCCCCCEEEECCCCCEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHEEEE
QGDRINAVRVSQALQLLQSTSPSYVLLASLDAARQQMALSGKQLMSRTLQLANEARERIS
ECCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIPGLSVLQPPTKTPSPGFTTLDKTRLTVTVSGLGLTGFAAEEILDEQLGVTAEFATLQH
HCCCCCEECCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHH
LTFIISLGNTATDIEQLVQGFTTLAETTLPTKALVNPKVNSNLEYFSEISPRDAFFADSE
HHEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHCCCCCCCEECCCC
TLSIEQACDGICAEIVCPYPPGIPVLMPGEVITKPAIEYLQHIQSLGGFITGCADTSLNT
CEEHHHHHCHHHHHEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCE
LKVLVNSH
EEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377; 1697575; 1936936 [H]