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The map label for this gene is recG [H]

Identifier: 17232281

GI number: 17232281

Start: 5704840

End: 5707308

Strand: Reverse

Name: recG [H]

Synonym: all4789

Alternate gene names: 17232281

Gene position: 5707308-5704840 (Counterclockwise)

Preceding gene: 17232282

Following gene: 17232274

Centisome position: 88.99

GC content: 44.63

Gene sequence:

>2469_bases
ATGAGCAATGACCAACCAGATTGGATAAGATTGCATAAAGCCTTAGCGGTGGAAGCAGAACACGGCTTTACAGACTTGCT
AGGTAAGCAATACCGCTTTAGTGAATTTCTCAGCTTGACTTTTGGGAAATTCCCGACGGTCTTACCTGCTATTGAACGTC
GTCGTTGGCAGGAATTGGCAGAGAAGTTTGCTAACTATCCTCATTTGGTACAGAAAGAAAGACAACATCTCATAGCGGAA
ACTCGTAGGTATCTTTACCAACTGCAAAAAGAGCAAGAAGAACCTAAAGAGGCGCAAGCAACCAGTTATAAATCAAAACT
TCCTAATGCGACCCCAGTTGTAGCGGAGGTAAGTCGGAGGTTAGCACCGAAAATTGACCAGAAACTCAGTGATTTACCAG
AAATAGGTATTCGCAAAGCCGATAAATTAGCGGCTTTACGTTTGTATACAGTGCGCGACTTGCTTTTTTACTATCCCCGT
GACCATATAGACTATGCGCGTCAGGTAAATATCCGCGAGTTGGAAGCGGGTGAGACGGTGACCATAGTAGCCACAGTCAA
AAAGTGTAATTGTTTTACTAGCCCCAAGAATCAAAAATTATCGATTTTAGAGTTAATACTTAAAGATAATACAGGTCAAA
TTAAAATCAGTCGTTTCTCGGCGGGGGCGCGGTTTACCAGTCGCGCTTGGCAGGAAAGTTTAAAACGCCGTTATCCTGTG
GGTAGTGTGTTGGCGGCTTGTGGGTTAGTTAAAGGGACTAAATACGGCTTGACGCTCGATAACCCCGAATTGGAAGTTTT
AGCGAACCCTGGAGACACTATTGAGTCTTTGACAATGGGGCGGGTAGTGCCGATTTACAGCCTCACCGAGGGAGTAATGG
CTAGTATGGTCAGACAGGCGGTACTTGCGGCCTTACCTGCGGCGGTGCATTTAAAAGACCCATTACCTAAAGGTTTGCGG
GAAAAATATGGTTTGATGGAATTGAAGGATGCGATCGCTAACATCCATTTTCCTGATGAAAGTGCTACCTTGCAAGTTGC
CCGTCGTCGCCTCGTTTTCGATGAATTTTTCTACCTGCAACTCGGTTTATTGCAACGTCAGCAGCAAGCGAAAGCGATTC
AAACTAGTGCAATTCTGGCTCCCAAAGGTAAGTTAATCGAAAATTTCTACGAAATACTACCATTTCAACTCACAGGCGCA
CAACAGCGAGTCCTGAACGACATCCTCAACGACTTACAAAAATCCGCACCGATGAATCGTTTAGTACAGGGTGATGTGGG
TTCAGGTAAAACTGTAGTGGCGGTGGTAGCAATTTTAGCTGCCATTCAATCTGGCTACCAAGCCGCGTTAATGGCTCCTA
CAGAAGTATTAGCAGAGCAACATTACCGTAAGTTAGTTAGCTGGTTTAACCTGCTGCATTTGCCAGTGGAATTACTTACA
GGCTCTACCAAAACTGTCAAAAGAAGACAGATACATTCCCAATTAGAAACAGGTGAATTACCCTTATTGGTGGGAACTCA
CGCTTTGATTCAAGACCCGGTAAATTTCCAGCGATTGGGTTTAGTTGTCATTGATGAACAGCATCGCTTTGGGGTCAAAC
AAAGGGCGCTGTTGCAGCAAAAAGGCGAACAACCCCATGTATTAACTATGACGGCTACACCCATTCCTCGGACACTGGCA
TTAACTATACACGGGGATATGAACGTCAGTCAAATTGATGAGTTACCACCAGGACGGCAAAAGATTCAGACCACAATGTT
AAGTGGTCAGCAACGTCCCCAAGCTTACGACCTCATCCGCCGAGAAATTGCCCAAGGTAGGCAAACTTATGTAGTCTTGC
CATTGGTAGAAGAATCAGAGAAACTAGATTTGCGATCAGCAGTAGAAGAACACCAAAAGTTACAAGAGAGCGTTTTTCCA
GATTTTCAAGTCGGTTTGCTACACGGTCGCATGAGTTCGGCGGAAAAGGACGAAGCTATTACCAAATTCCGCGACAATGA
AACGCAGATTCTTGTATCTACAACCGTTGTTGAAGTTGGTGTGGATGTACCCAATGCAACAGTCATGCTCATAGAAAATG
CTGAAAGATTCGGCTTGTCACAACTACATCAATTGCGCGGGCGTGTGGGTCGAGGTGCAGCCCAGTCTTACTGTTTATTA
ATGAGTAGTTCTAGAAGCCCTGACGCTCAACAACGTCTGAAAGTATTAGAACAGTCTCAAGACGGCTTTTTCATCTCCGA
AATGGATATGCGTTTTCGTGGGCCGGGTGAAGTGTTAGGAACAAGGCAATCTGGTGTGCCTGATTTTACCTTAGCTAGTT
TAGTAGAAGATGAAGAAGTTTTATTATTAGCCAGACAAGCCGCCGAGAAAGTAATAGAAATAGATGCCAGTTTAGAGCGT
TGGGCTTTGATGAAAGCAGAGTTGAAATATCGCTATGAACGCTTGATGGGTGGGGCAATTTTAACTTGA

Upstream 100 bases:

>100_bases
TATGAGGATTAGTTAGTTGTCAGTTGTTATTAGCATTGGTCATAATACTGACTCTGATTGTATTGATTTTGAATTTTGAA
TTCCCCTTAGGGGTTGACTA

Downstream 100 bases:

>100_bases
TAAACTCAGCCCTCACAATAGTAATTGATCCTTACCAATTACCAATAACCAACCCCCACAGATATTATCTATAGGACTTA
CGCAAACACGTTATCTGTTG

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 822; Mature: 821

Protein sequence:

>822_residues
MSNDQPDWIRLHKALAVEAEHGFTDLLGKQYRFSEFLSLTFGKFPTVLPAIERRRWQELAEKFANYPHLVQKERQHLIAE
TRRYLYQLQKEQEEPKEAQATSYKSKLPNATPVVAEVSRRLAPKIDQKLSDLPEIGIRKADKLAALRLYTVRDLLFYYPR
DHIDYARQVNIRELEAGETVTIVATVKKCNCFTSPKNQKLSILELILKDNTGQIKISRFSAGARFTSRAWQESLKRRYPV
GSVLAACGLVKGTKYGLTLDNPELEVLANPGDTIESLTMGRVVPIYSLTEGVMASMVRQAVLAALPAAVHLKDPLPKGLR
EKYGLMELKDAIANIHFPDESATLQVARRRLVFDEFFYLQLGLLQRQQQAKAIQTSAILAPKGKLIENFYEILPFQLTGA
QQRVLNDILNDLQKSAPMNRLVQGDVGSGKTVVAVVAILAAIQSGYQAALMAPTEVLAEQHYRKLVSWFNLLHLPVELLT
GSTKTVKRRQIHSQLETGELPLLVGTHALIQDPVNFQRLGLVVIDEQHRFGVKQRALLQQKGEQPHVLTMTATPIPRTLA
LTIHGDMNVSQIDELPPGRQKIQTTMLSGQQRPQAYDLIRREIAQGRQTYVVLPLVEESEKLDLRSAVEEHQKLQESVFP
DFQVGLLHGRMSSAEKDEAITKFRDNETQILVSTTVVEVGVDVPNATVMLIENAERFGLSQLHQLRGRVGRGAAQSYCLL
MSSSRSPDAQQRLKVLEQSQDGFFISEMDMRFRGPGEVLGTRQSGVPDFTLASLVEDEEVLLLARQAAEKVIEIDASLER
WALMKAELKYRYERLMGGAILT

Sequences:

>Translated_822_residues
MSNDQPDWIRLHKALAVEAEHGFTDLLGKQYRFSEFLSLTFGKFPTVLPAIERRRWQELAEKFANYPHLVQKERQHLIAE
TRRYLYQLQKEQEEPKEAQATSYKSKLPNATPVVAEVSRRLAPKIDQKLSDLPEIGIRKADKLAALRLYTVRDLLFYYPR
DHIDYARQVNIRELEAGETVTIVATVKKCNCFTSPKNQKLSILELILKDNTGQIKISRFSAGARFTSRAWQESLKRRYPV
GSVLAACGLVKGTKYGLTLDNPELEVLANPGDTIESLTMGRVVPIYSLTEGVMASMVRQAVLAALPAAVHLKDPLPKGLR
EKYGLMELKDAIANIHFPDESATLQVARRRLVFDEFFYLQLGLLQRQQQAKAIQTSAILAPKGKLIENFYEILPFQLTGA
QQRVLNDILNDLQKSAPMNRLVQGDVGSGKTVVAVVAILAAIQSGYQAALMAPTEVLAEQHYRKLVSWFNLLHLPVELLT
GSTKTVKRRQIHSQLETGELPLLVGTHALIQDPVNFQRLGLVVIDEQHRFGVKQRALLQQKGEQPHVLTMTATPIPRTLA
LTIHGDMNVSQIDELPPGRQKIQTTMLSGQQRPQAYDLIRREIAQGRQTYVVLPLVEESEKLDLRSAVEEHQKLQESVFP
DFQVGLLHGRMSSAEKDEAITKFRDNETQILVSTTVVEVGVDVPNATVMLIENAERFGLSQLHQLRGRVGRGAAQSYCLL
MSSSRSPDAQQRLKVLEQSQDGFFISEMDMRFRGPGEVLGTRQSGVPDFTLASLVEDEEVLLLARQAAEKVIEIDASLER
WALMKAELKYRYERLMGGAILT
>Mature_821_residues
SNDQPDWIRLHKALAVEAEHGFTDLLGKQYRFSEFLSLTFGKFPTVLPAIERRRWQELAEKFANYPHLVQKERQHLIAET
RRYLYQLQKEQEEPKEAQATSYKSKLPNATPVVAEVSRRLAPKIDQKLSDLPEIGIRKADKLAALRLYTVRDLLFYYPRD
HIDYARQVNIRELEAGETVTIVATVKKCNCFTSPKNQKLSILELILKDNTGQIKISRFSAGARFTSRAWQESLKRRYPVG
SVLAACGLVKGTKYGLTLDNPELEVLANPGDTIESLTMGRVVPIYSLTEGVMASMVRQAVLAALPAAVHLKDPLPKGLRE
KYGLMELKDAIANIHFPDESATLQVARRRLVFDEFFYLQLGLLQRQQQAKAIQTSAILAPKGKLIENFYEILPFQLTGAQ
QRVLNDILNDLQKSAPMNRLVQGDVGSGKTVVAVVAILAAIQSGYQAALMAPTEVLAEQHYRKLVSWFNLLHLPVELLTG
STKTVKRRQIHSQLETGELPLLVGTHALIQDPVNFQRLGLVVIDEQHRFGVKQRALLQQKGEQPHVLTMTATPIPRTLAL
TIHGDMNVSQIDELPPGRQKIQTTMLSGQQRPQAYDLIRREIAQGRQTYVVLPLVEESEKLDLRSAVEEHQKLQESVFPD
FQVGLLHGRMSSAEKDEAITKFRDNETQILVSTTVVEVGVDVPNATVMLIENAERFGLSQLHQLRGRVGRGAAQSYCLLM
SSSRSPDAQQRLKVLEQSQDGFFISEMDMRFRGPGEVLGTRQSGVPDFTLASLVEDEEVLLLARQAAEKVIEIDASLERW
ALMKAELKYRYERLMGGAILT

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=698, Percent_Identity=40.974212034384, Blast_Score=435, Evalue=1e-123,
Organism=Escherichia coli, GI1787357, Length=383, Percent_Identity=36.0313315926893, Blast_Score=248, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 92498; Mature: 92367

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNDQPDWIRLHKALAVEAEHGFTDLLGKQYRFSEFLSLTFGKFPTVLPAIERRRWQELA
CCCCCCHHHHHHHHHHEECCCCHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EKFANYPHLVQKERQHLIAETRRYLYQLQKEQEEPKEAQATSYKSKLPNATPVVAEVSRR
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHH
LAPKIDQKLSDLPEIGIRKADKLAALRLYTVRDLLFYYPRDHIDYARQVNIRELEAGETV
HHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEECCCCEE
TIVATVKKCNCFTSPKNQKLSILELILKDNTGQIKISRFSAGARFTSRAWQESLKRRYPV
EEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCH
GSVLAACGLVKGTKYGLTLDNPELEVLANPGDTIESLTMGRVVPIYSLTEGVMASMVRQA
HHHHHHHHHHCCCCCCEEECCCCEEEEECCCCHHHHHHCCCEEHHHHHHHHHHHHHHHHH
VLAALPAAVHLKDPLPKGLREKYGLMELKDAIANIHFPDESATLQVARRRLVFDEFFYLQ
HHHHCCHHHCCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LGLLQRQQQAKAIQTSAILAPKGKLIENFYEILPFQLTGAQQRVLNDILNDLQKSAPMNR
HHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHH
LVQGDVGSGKTVVAVVAILAAIQSGYQAALMAPTEVLAEQHYRKLVSWFNLLHLPVELLT
HHCCCCCCCHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GSTKTVKRRQIHSQLETGELPLLVGTHALIQDPVNFQRLGLVVIDEQHRFGVKQRALLQQ
CCHHHHHHHHHHHHHCCCCCCEEECCHHHHHCCCCHHHEEEEEEECHHHCCHHHHHHHHH
KGEQPHVLTMTATPIPRTLALTIHGDMNVSQIDELPPGRQKIQTTMLSGQQRPQAYDLIR
CCCCCEEEEEECCCCCCEEEEEEECCCCHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHH
REIAQGRQTYVVLPLVEESEKLDLRSAVEEHQKLQESVFPDFQVGLLHGRMSSAEKDEAI
HHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHH
TKFRDNETQILVSTTVVEVGVDVPNATVMLIENAERFGLSQLHQLRGRVGRGAAQSYCLL
HHHCCCCCEEEEEEEEEEECCCCCCCEEEEEECCHHCCHHHHHHHHHHHCCCHHHHEEEE
MSSSRSPDAQQRLKVLEQSQDGFFISEMDMRFRGPGEVLGTRQSGVPDFTLASLVEDEEV
EECCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCHHCCCCCCCCCCHHHHHHHCCHHH
LLLARQAAEKVIEIDASLERWALMKAELKYRYERLMGGAILT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SNDQPDWIRLHKALAVEAEHGFTDLLGKQYRFSEFLSLTFGKFPTVLPAIERRRWQELA
CCCCCHHHHHHHHHHEECCCCHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EKFANYPHLVQKERQHLIAETRRYLYQLQKEQEEPKEAQATSYKSKLPNATPVVAEVSRR
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHH
LAPKIDQKLSDLPEIGIRKADKLAALRLYTVRDLLFYYPRDHIDYARQVNIRELEAGETV
HHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEECCCCEE
TIVATVKKCNCFTSPKNQKLSILELILKDNTGQIKISRFSAGARFTSRAWQESLKRRYPV
EEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCH
GSVLAACGLVKGTKYGLTLDNPELEVLANPGDTIESLTMGRVVPIYSLTEGVMASMVRQA
HHHHHHHHHHCCCCCCEEECCCCEEEEECCCCHHHHHHCCCEEHHHHHHHHHHHHHHHHH
VLAALPAAVHLKDPLPKGLREKYGLMELKDAIANIHFPDESATLQVARRRLVFDEFFYLQ
HHHHCCHHHCCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LGLLQRQQQAKAIQTSAILAPKGKLIENFYEILPFQLTGAQQRVLNDILNDLQKSAPMNR
HHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHH
LVQGDVGSGKTVVAVVAILAAIQSGYQAALMAPTEVLAEQHYRKLVSWFNLLHLPVELLT
HHCCCCCCCHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GSTKTVKRRQIHSQLETGELPLLVGTHALIQDPVNFQRLGLVVIDEQHRFGVKQRALLQQ
CCHHHHHHHHHHHHHCCCCCCEEECCHHHHHCCCCHHHEEEEEEECHHHCCHHHHHHHHH
KGEQPHVLTMTATPIPRTLALTIHGDMNVSQIDELPPGRQKIQTTMLSGQQRPQAYDLIR
CCCCCEEEEEECCCCCCEEEEEEECCCCHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHH
REIAQGRQTYVVLPLVEESEKLDLRSAVEEHQKLQESVFPDFQVGLLHGRMSSAEKDEAI
HHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHH
TKFRDNETQILVSTTVVEVGVDVPNATVMLIENAERFGLSQLHQLRGRVGRGAAQSYCLL
HHHCCCCCEEEEEEEEEEECCCCCCCEEEEEECCHHCCHHHHHHHHHHHCCCHHHHEEEE
MSSSRSPDAQQRLKVLEQSQDGFFISEMDMRFRGPGEVLGTRQSGVPDFTLASLVEDEEV
EECCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCHHCCCCCCCCCCHHHHHHHCCHHH
LLLARQAAEKVIEIDASLERWALMKAELKYRYERLMGGAILT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]