Click here to switch to the map view.

The map label for this gene is ppnK [H]

Identifier: 17232243

GI number: 17232243

Start: 5664299

End: 5665216

Strand: Reverse

Name: ppnK [H]

Synonym: all4751

Alternate gene names: 17232243

Gene position: 5665216-5664299 (Counterclockwise)

Preceding gene: 17232244

Following gene: 17232242

Centisome position: 88.33

GC content: 47.49

Gene sequence:

>918_bases
GTGCCGAAAGTAGGCATTATATACAACGACATTAAACCGGTAGCCGGTCGTGTTGCTATCGAGTTAAAAGATAAGCTAAC
CGCAGCCGGTTGGGATGTATCTATCACATCTAGTATCGGTGGCATATTGGGCTACTCTAATCCTGAAAGCCCTGTGTGCC
ACACGCCAATTGACGGTTTGACACCCCCTGGGTTTGATTCAGAAATGAAGTTTGCCATAGTGCTGGGGGGTGACGGTACC
GTTTTAGCCGCATCGCGTCAGGTAGCGCCTTGCGGTATTCCGATTTTGGCCATAAATACCGGACACATGGGGTTCTTAAC
GGAAACTTACCTGAATCAATTACCCCAAGCTATAGATCAGGCGATCGCAGGTGAGTATGAAATCGAAGAACGAGCCATGC
TCACGGTCAAAGTGCTGCGAGGAGAGTCAGTACTTTGGGAAGCTCTATGCTTGAACGAAATGGTTTTGCATCGTGAACCA
TTAACGTCAATGTGTCATTTTGAGATTGCTGTAGGTCGTCATGCGCCAGTTGATATTGCCGCAGATGGGGTAATTGTTTC
TACACCTACAGGCTCCACCGCTTACTCTTTAAGCGCAGGTGGGCCAGTTGTTGCCCCCGGTGTACCCGTATTGCAGCTCG
TTCCTATTTGTCCCCATTCTTTGGCTTCCAGGGCTTTAGTATTTCCCGATACTGAACCAGTCAATATTTACCCGGTGAAC
ATTCCCCGGTTGGTGATGGTAGTAGATGGCAATGGGGGATGCTATATTTTTCCAGAAGATAGAGTATATCTAGAGCGATC
GCCATACAGTGTCAAATTTATTCGCCTCCAACCACCAGAATTTTTCCGTATTTTGCGAGAAAAACTCGGTTGGGGTCTAC
CGCATATCGCTAAACCAACTTCGGTAGAATTACCTTAG

Upstream 100 bases:

>100_bases
CCATAGACTATAGACTTTTGATGCCAAACTAATGACTGGTGATCCAAAATGTGTAACGATTACAAAAGACAAAGCGTCGC
TTAAACCTGGATATTTGAGT

Downstream 100 bases:

>100_bases
TCAACAGTCAATAGTTATTCTCCTTTTCCCCACTCCCCATTTATTGCCTATACAATTAAACATCCAAATATCCCAAAATC
TTATGATAGCTACTCATAGC

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase 1 [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MPKVGIIYNDIKPVAGRVAIELKDKLTAAGWDVSITSSIGGILGYSNPESPVCHTPIDGLTPPGFDSEMKFAIVLGGDGT
VLAASRQVAPCGIPILAINTGHMGFLTETYLNQLPQAIDQAIAGEYEIEERAMLTVKVLRGESVLWEALCLNEMVLHREP
LTSMCHFEIAVGRHAPVDIAADGVIVSTPTGSTAYSLSAGGPVVAPGVPVLQLVPICPHSLASRALVFPDTEPVNIYPVN
IPRLVMVVDGNGGCYIFPEDRVYLERSPYSVKFIRLQPPEFFRILREKLGWGLPHIAKPTSVELP

Sequences:

>Translated_305_residues
MPKVGIIYNDIKPVAGRVAIELKDKLTAAGWDVSITSSIGGILGYSNPESPVCHTPIDGLTPPGFDSEMKFAIVLGGDGT
VLAASRQVAPCGIPILAINTGHMGFLTETYLNQLPQAIDQAIAGEYEIEERAMLTVKVLRGESVLWEALCLNEMVLHREP
LTSMCHFEIAVGRHAPVDIAADGVIVSTPTGSTAYSLSAGGPVVAPGVPVLQLVPICPHSLASRALVFPDTEPVNIYPVN
IPRLVMVVDGNGGCYIFPEDRVYLERSPYSVKFIRLQPPEFFRILREKLGWGLPHIAKPTSVELP
>Mature_304_residues
PKVGIIYNDIKPVAGRVAIELKDKLTAAGWDVSITSSIGGILGYSNPESPVCHTPIDGLTPPGFDSEMKFAIVLGGDGTV
LAASRQVAPCGIPILAINTGHMGFLTETYLNQLPQAIDQAIAGEYEIEERAMLTVKVLRGESVLWEALCLNEMVLHREPL
TSMCHFEIAVGRHAPVDIAADGVIVSTPTGSTAYSLSAGGPVVAPGVPVLQLVPICPHSLASRALVFPDTEPVNIYPVNI
PRLVMVVDGNGGCYIFPEDRVYLERSPYSVKFIRLQPPEFFRILREKLGWGLPHIAKPTSVELP

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=257, Percent_Identity=30.3501945525292, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1788968, Length=222, Percent_Identity=33.7837837837838, Blast_Score=135, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6320794, Length=257, Percent_Identity=32.295719844358, Blast_Score=123, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6322509, Length=244, Percent_Identity=31.5573770491803, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6325068, Length=168, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI28573828, Length=253, Percent_Identity=28.8537549407115, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28573832, Length=254, Percent_Identity=28.740157480315, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI28573830, Length=254, Percent_Identity=28.740157480315, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI28573826, Length=254, Percent_Identity=28.740157480315, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI161077047, Length=253, Percent_Identity=28.8537549407115, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI20129957, Length=278, Percent_Identity=27.3381294964029, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281363321, Length=279, Percent_Identity=27.2401433691756, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281363323, Length=278, Percent_Identity=27.3381294964029, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24653424, Length=279, Percent_Identity=27.2401433691756, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24653422, Length=278, Percent_Identity=27.3381294964029, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 32799; Mature: 32667

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKVGIIYNDIKPVAGRVAIELKDKLTAAGWDVSITSSIGGILGYSNPESPVCHTPIDGL
CCCCEEEEECCCCCCCEEEEEEECCEEECCCCEEECCCCCCEECCCCCCCCEEECCCCCC
TPPGFDSEMKFAIVLGGDGTVLAASRQVAPCGIPILAINTGHMGFLTETYLNQLPQAIDQ
CCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
AIAGEYEIEERAMLTVKVLRGESVLWEALCLNEMVLHREPLTSMCHFEIAVGRHAPVDIA
HHCCCCEECCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHEEEEEEECCCCCCEEE
ADGVIVSTPTGSTAYSLSAGGPVVAPGVPVLQLVPICPHSLASRALVFPDTEPVNIYPVN
ECCEEEECCCCCCEEEECCCCCEECCCCCCEEEECCCCHHHHCCEEECCCCCCCEEEEEC
IPRLVMVVDGNGGCYIFPEDRVYLERSPYSVKFIRLQPPEFFRILREKLGWGLPHIAKPT
CCEEEEEEECCCCEEEEECCEEEEECCCCEEEEEEECCHHHHHHHHHHHCCCCCCCCCCC
SVELP
CCCCC
>Mature Secondary Structure 
PKVGIIYNDIKPVAGRVAIELKDKLTAAGWDVSITSSIGGILGYSNPESPVCHTPIDGL
CCCEEEEECCCCCCCEEEEEEECCEEECCCCEEECCCCCCEECCCCCCCCEEECCCCCC
TPPGFDSEMKFAIVLGGDGTVLAASRQVAPCGIPILAINTGHMGFLTETYLNQLPQAIDQ
CCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
AIAGEYEIEERAMLTVKVLRGESVLWEALCLNEMVLHREPLTSMCHFEIAVGRHAPVDIA
HHCCCCEECCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHEEEEEEECCCCCCEEE
ADGVIVSTPTGSTAYSLSAGGPVVAPGVPVLQLVPICPHSLASRALVFPDTEPVNIYPVN
ECCEEEECCCCCCEEEECCCCCEECCCCCCEEEECCCCHHHHCCEEECCCCCCCEEEEEC
IPRLVMVVDGNGGCYIFPEDRVYLERSPYSVKFIRLQPPEFFRILREKLGWGLPHIAKPT
CCEEEEEEECCCCEEEEECCEEEEECCCCEEEEEEECCHHHHHHHHHHHCCCCCCCCCCC
SVELP
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA