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The map label for this gene is galE [H]

Identifier: 17232205

GI number: 17232205

Start: 5617552

End: 5618550

Strand: Reverse

Name: galE [H]

Synonym: all4713

Alternate gene names: 17232205

Gene position: 5618550-5617552 (Counterclockwise)

Preceding gene: 17232211

Following gene: 17232202

Centisome position: 87.6

GC content: 43.04

Gene sequence:

>999_bases
ATGTCGCCTGGAAAGCCCAGCATTTTGGTAACGGGGGGAGCAGGATATATTGGTTCGCACACTGTCCTGGCTCTCAAGCA
AGCAGGTTATGACGTGGTGATACTAGATAATTTGGTCTATGGACATCGTGATTTAGTAGAAAAAGTTTTACAAGTTGAAT
TGGTGGTGGGTGATACAGGCGATCGCCCTTTATTAGATGAGTTATTTAAATCACGCCATTTTGATGCAGTAATGCACTTT
TCCGCTTACGCTTATGTAGGCGAATCTGTGAGTGATCCTGCCAAATACTATCGCAATAATGTTTTAGGCACATTGACGTT
ATTAGAAGCGATGCTGGCTGCTTCAATTAATAAGTTTGTCTTTTCTTCCACTTGTGCCACTTATGGAGTGCCAAAAACTG
TTCCTATTCCCGAAGATCATCCCCAAAACCCCATTAATCCTTATGGTGCTACTAAGTTAATGGTGGAAAGGATACTGGCG
GATTTTGATGTGGCTTATGGTTTGAAATCAGTCCGTTTCCGTTACTTTAATGCGGCTGGTGCTAATCCTGATGGGTTGCT
AGGTGAGGATCACAACCCCGAAACTCATTTAATTCCTTTAGTACTACTAACAGCCTTAGGCAAACGTAAATTTATTTCCA
TTTTCGGAACTGATTACCCCACACCCGATGGCACTTGTATTCGGGATTATATTCACGTTAACGACTTAGCCGATGCCCAC
GTTTTGGGATTGAAATATTTATTAAAAGGTGGAGATAGCGAAGTTTTTAATTTGGGTAATGGCCAAGGTTTCTCAGTCAG
AGAAGTAATTGCGGCTGGTGAACAAGTCACAGGATTACCCATAACCGTTGAAGAATGCGATCGCCGTCCTGGAGATCCCC
CAAGTCTCATTGGTAGTGGTGAGAAAGCCAGAAAAATTCTTGGCTGGCAACCCCAATACTCATCAATCAAAGATATCGTT
TCCCATGCCTGGCAATGGCATCAGAAGCGCCATCAATAG

Upstream 100 bases:

>100_bases
GGGGTTGGGAATTGGGTACTCACCACTCATTACTCAGCACAGTACTTTCTACCTTTCTTGCTAAATTAATTGAGTAGTTG
TCAACTCAAAAGGAAAAACT

Downstream 100 bases:

>100_bases
CAATTCAAAATTCAAAATTCAAAATTACTAGATCCCCGACTTCTTCAAGAAGTCGGGGATCTAGGGCTTGTTTTTATTTC
GCCAAATAGCCAATACTATA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MSPGKPSILVTGGAGYIGSHTVLALKQAGYDVVILDNLVYGHRDLVEKVLQVELVVGDTGDRPLLDELFKSRHFDAVMHF
SAYAYVGESVSDPAKYYRNNVLGTLTLLEAMLAASINKFVFSSTCATYGVPKTVPIPEDHPQNPINPYGATKLMVERILA
DFDVAYGLKSVRFRYFNAAGANPDGLLGEDHNPETHLIPLVLLTALGKRKFISIFGTDYPTPDGTCIRDYIHVNDLADAH
VLGLKYLLKGGDSEVFNLGNGQGFSVREVIAAGEQVTGLPITVEECDRRPGDPPSLIGSGEKARKILGWQPQYSSIKDIV
SHAWQWHQKRHQ

Sequences:

>Translated_332_residues
MSPGKPSILVTGGAGYIGSHTVLALKQAGYDVVILDNLVYGHRDLVEKVLQVELVVGDTGDRPLLDELFKSRHFDAVMHF
SAYAYVGESVSDPAKYYRNNVLGTLTLLEAMLAASINKFVFSSTCATYGVPKTVPIPEDHPQNPINPYGATKLMVERILA
DFDVAYGLKSVRFRYFNAAGANPDGLLGEDHNPETHLIPLVLLTALGKRKFISIFGTDYPTPDGTCIRDYIHVNDLADAH
VLGLKYLLKGGDSEVFNLGNGQGFSVREVIAAGEQVTGLPITVEECDRRPGDPPSLIGSGEKARKILGWQPQYSSIKDIV
SHAWQWHQKRHQ
>Mature_331_residues
SPGKPSILVTGGAGYIGSHTVLALKQAGYDVVILDNLVYGHRDLVEKVLQVELVVGDTGDRPLLDELFKSRHFDAVMHFS
AYAYVGESVSDPAKYYRNNVLGTLTLLEAMLAASINKFVFSSTCATYGVPKTVPIPEDHPQNPINPYGATKLMVERILAD
FDVAYGLKSVRFRYFNAAGANPDGLLGEDHNPETHLIPLVLLTALGKRKFISIFGTDYPTPDGTCIRDYIHVNDLADAHV
LGLKYLLKGGDSEVFNLGNGQGFSVREVIAAGEQVTGLPITVEECDRRPGDPPSLIGSGEKARKILGWQPQYSSIKDIVS
HAWQWHQKRHQ

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=336, Percent_Identity=39.2857142857143, Blast_Score=230, Evalue=1e-60,
Organism=Homo sapiens, GI56118217, Length=336, Percent_Identity=39.2857142857143, Blast_Score=230, Evalue=1e-60,
Organism=Homo sapiens, GI189083684, Length=336, Percent_Identity=39.2857142857143, Blast_Score=230, Evalue=1e-60,
Organism=Homo sapiens, GI7657641, Length=317, Percent_Identity=26.4984227129338, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI42516563, Length=316, Percent_Identity=26.5822784810127, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1786974, Length=332, Percent_Identity=41.566265060241, Blast_Score=248, Evalue=3e-67,
Organism=Escherichia coli, GI1788353, Length=337, Percent_Identity=30.5637982195846, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI48994969, Length=340, Percent_Identity=29.7058823529412, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790049, Length=271, Percent_Identity=29.520295202952, Blast_Score=82, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71982035, Length=342, Percent_Identity=38.3040935672515, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI71982038, Length=344, Percent_Identity=38.3720930232558, Blast_Score=222, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17568069, Length=266, Percent_Identity=29.6992481203008, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17539532, Length=318, Percent_Identity=27.0440251572327, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI115532424, Length=353, Percent_Identity=24.6458923512748, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=336, Percent_Identity=41.6666666666667, Blast_Score=241, Evalue=2e-64,
Organism=Drosophila melanogaster, GI19923002, Length=347, Percent_Identity=40.3458213256484, Blast_Score=245, Evalue=3e-65,
Organism=Drosophila melanogaster, GI21356223, Length=318, Percent_Identity=26.7295597484277, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36374; Mature: 36243

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPGKPSILVTGGAGYIGSHTVLALKQAGYDVVILDNLVYGHRDLVEKVLQVELVVGDTG
CCCCCCCEEEECCCCCCCCHHEEEEHHCCCEEEEECCHHHCCHHHHHHHHEEEEEEECCC
DRPLLDELFKSRHFDAVMHFSAYAYVGESVSDPAKYYRNNVLGTLTLLEAMLAASINKFV
CCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHH
FSSTCATYGVPKTVPIPEDHPQNPINPYGATKLMVERILADFDVAYGLKSVRFRYFNAAG
HHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCC
ANPDGLLGEDHNPETHLIPLVLLTALGKRKFISIFGTDYPTPDGTCIRDYIHVNDLADAH
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHEEECCCCCHHH
VLGLKYLLKGGDSEVFNLGNGQGFSVREVIAAGEQVTGLPITVEECDRRPGDPPSLIGSG
HHHHHHHHCCCCCCEEECCCCCCCHHHHHHHCCCCCCCCEEEHHHHHCCCCCCHHHCCCC
EKARKILGWQPQYSSIKDIVSHAWQWHQKRHQ
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SPGKPSILVTGGAGYIGSHTVLALKQAGYDVVILDNLVYGHRDLVEKVLQVELVVGDTG
CCCCCCEEEECCCCCCCCHHEEEEHHCCCEEEEECCHHHCCHHHHHHHHEEEEEEECCC
DRPLLDELFKSRHFDAVMHFSAYAYVGESVSDPAKYYRNNVLGTLTLLEAMLAASINKFV
CCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHH
FSSTCATYGVPKTVPIPEDHPQNPINPYGATKLMVERILADFDVAYGLKSVRFRYFNAAG
HHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCC
ANPDGLLGEDHNPETHLIPLVLLTALGKRKFISIFGTDYPTPDGTCIRDYIHVNDLADAH
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHEEECCCCCHHH
VLGLKYLLKGGDSEVFNLGNGQGFSVREVIAAGEQVTGLPITVEECDRRPGDPPSLIGSG
HHHHHHHHCCCCCCEEECCCCCCCHHHHHHHCCCCCCCCEEEHHHHHCCCCCCHHHCCCC
EKARKILGWQPQYSSIKDIVSHAWQWHQKRHQ
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]