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The map label for this gene is fda [H]

Identifier: 17232055

GI number: 17232055

Start: 5457511

End: 5458590

Strand: Reverse

Name: fda [H]

Synonym: all4563

Alternate gene names: 17232055

Gene position: 5458590-5457511 (Counterclockwise)

Preceding gene: 17232057

Following gene: 17232054

Centisome position: 85.11

GC content: 47.69

Gene sequence:

>1080_bases
ATGGCGCTTGTACCATTGCGGCTGCTTTTGGATCACGCGGCTGAAAACGGTTACGGCATCCCAGCTTTCAACGTTAACAA
TTTGGAGCAGATTCAGGCAATCCTGAAGGCTGCTGCCGAGACAGATAGCCCCGTAATTTTGCAAGCTTCTCGTGGCGCTC
GTAATTATGCAGGTGAAAACTTCCTCCGCCACCTGATTTTGGCTGCGGTAGAAACCTATCCTGAGATTCCCATCGTCATG
CACCAGGATCATGGTAATGCTCCTTCTACCTGCTACTCAGCAATCAAGAACAACTTCACCAGCGTCATGATGGATGGTTC
TTTAGAAGCTGATGCTAAAACCCCTGCTAGCTTCGAGTACAACGTCAATGTTACCCGCGAAGTTGTAAATGTAGCTCATG
CTTTGGGCGTAAGTGTAGAAGGTGAACTCGGTTGTTTGGGTTCTCTGGAAACCGGTGCGGGTGAAGCTGAAGACGGACAC
GGTTTTGAAGGTACTCTTGACCATTCCCAACTGTTAACTGACCCCGATGAAGCTGTTAACTTCGTAGAAGCAACCCAAGT
AGATGCTTTGGCTGTAGCTATCGGTACCAGCCACGGTGCTTACAAGTTTACCCGCAAACCCACCGGCGAAATTTTGGCTA
TCAGCCGCATTGAAGAAATTCACCGCCGTCTACCTAACACCCACTTGGTAATGCACGGTTCTTCTTCCGTACCTGAAGAT
TTAATCGCTTTGATTAACGAGTACGGTGGTGCTATTCCTGAAACCTACGGTGTACCTGTAGAAGAAATCCAAAAAGGTAT
CAAGAGTGGTGTTCGCAAAGTGAACATCGACACCGACAACCGCCTGGCTATCACTGCGGCTGTGCGCGAAGCTTTAGCAA
AAAATCCCAAGGAGTTTGACCCCCGTCACTTCCTCAAGCCTTCTATTACATATATGCAGAAGGTTTGTGCAGAACGCTAT
GTACAATTCGGTACTGCTGGCAATGCTAGCAAGATTAAGCAAGTTTCTCTAGAAACTTTTGCTGCTAAGTATGCTAAAGG
CGAATTGAACGCTATCAGCAAGGCTGCTGCTAAGGTTTAA

Upstream 100 bases:

>100_bases
GTTATAATTTCCTATAAGTTGAAAAAACTATTAAGATTTAGCGTAATCACTACGCTGCTTTCACACCCACTAGCTGACAA
CCACATTAGGAGGACTATCT

Downstream 100 bases:

>100_bases
TTTTAGTCAAAGATAAATAGGGGCATGATTTTGCTCCTGCAAAATTTTTGATATTGATATAAATAAACCGGGATACCTAA
AAGTGTCCTGGTTTTTTGTT

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MALVPLRLLLDHAAENGYGIPAFNVNNLEQIQAILKAAAETDSPVILQASRGARNYAGENFLRHLILAAVETYPEIPIVM
HQDHGNAPSTCYSAIKNNFTSVMMDGSLEADAKTPASFEYNVNVTREVVNVAHALGVSVEGELGCLGSLETGAGEAEDGH
GFEGTLDHSQLLTDPDEAVNFVEATQVDALAVAIGTSHGAYKFTRKPTGEILAISRIEEIHRRLPNTHLVMHGSSSVPED
LIALINEYGGAIPETYGVPVEEIQKGIKSGVRKVNIDTDNRLAITAAVREALAKNPKEFDPRHFLKPSITYMQKVCAERY
VQFGTAGNASKIKQVSLETFAAKYAKGELNAISKAAAKV

Sequences:

>Translated_359_residues
MALVPLRLLLDHAAENGYGIPAFNVNNLEQIQAILKAAAETDSPVILQASRGARNYAGENFLRHLILAAVETYPEIPIVM
HQDHGNAPSTCYSAIKNNFTSVMMDGSLEADAKTPASFEYNVNVTREVVNVAHALGVSVEGELGCLGSLETGAGEAEDGH
GFEGTLDHSQLLTDPDEAVNFVEATQVDALAVAIGTSHGAYKFTRKPTGEILAISRIEEIHRRLPNTHLVMHGSSSVPED
LIALINEYGGAIPETYGVPVEEIQKGIKSGVRKVNIDTDNRLAITAAVREALAKNPKEFDPRHFLKPSITYMQKVCAERY
VQFGTAGNASKIKQVSLETFAAKYAKGELNAISKAAAKV
>Mature_358_residues
ALVPLRLLLDHAAENGYGIPAFNVNNLEQIQAILKAAAETDSPVILQASRGARNYAGENFLRHLILAAVETYPEIPIVMH
QDHGNAPSTCYSAIKNNFTSVMMDGSLEADAKTPASFEYNVNVTREVVNVAHALGVSVEGELGCLGSLETGAGEAEDGHG
FEGTLDHSQLLTDPDEAVNFVEATQVDALAVAIGTSHGAYKFTRKPTGEILAISRIEEIHRRLPNTHLVMHGSSSVPEDL
IALINEYGGAIPETYGVPVEEIQKGIKSGVRKVNIDTDNRLAITAAVREALAKNPKEFDPRHFLKPSITYMQKVCAERYV
QFGTAGNASKIKQVSLETFAAKYAKGELNAISKAAAKV

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=331, Percent_Identity=34.1389728096677, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI87082041, Length=329, Percent_Identity=32.5227963525836, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1788072, Length=289, Percent_Identity=31.8339100346021, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1789293, Length=351, Percent_Identity=25.6410256410256, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006412
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 38617; Mature: 38486

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVPLRLLLDHAAENGYGIPAFNVNNLEQIQAILKAAAETDSPVILQASRGARNYAGEN
CCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHH
FLRHLILAAVETYPEIPIVMHQDHGNAPSTCYSAIKNNFTSVMMDGSLEADAKTPASFEY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEE
NVNVTREVVNVAHALGVSVEGELGCLGSLETGAGEAEDGHGFEGTLDHSQLLTDPDEAVN
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHH
FVEATQVDALAVAIGTSHGAYKFTRKPTGEILAISRIEEIHRRLPNTHLVMHGSSSVPED
HHHHHHHHEEEEEEECCCCCEEECCCCCCCEEHHHHHHHHHHHCCCCEEEEECCCCCHHH
LIALINEYGGAIPETYGVPVEEIQKGIKSGVRKVNIDTDNRLAITAAVREALAKNPKEFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCEEHHHHHHHHHHCCCCCCC
PRHFLKPSITYMQKVCAERYVQFGTAGNASKIKQVSLETFAAKYAKGELNAISKAAAKV
CHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure 
ALVPLRLLLDHAAENGYGIPAFNVNNLEQIQAILKAAAETDSPVILQASRGARNYAGEN
CCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHH
FLRHLILAAVETYPEIPIVMHQDHGNAPSTCYSAIKNNFTSVMMDGSLEADAKTPASFEY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEE
NVNVTREVVNVAHALGVSVEGELGCLGSLETGAGEAEDGHGFEGTLDHSQLLTDPDEAVN
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHH
FVEATQVDALAVAIGTSHGAYKFTRKPTGEILAISRIEEIHRRLPNTHLVMHGSSSVPED
HHHHHHHHEEEEEEECCCCCEEECCCCCCCEEHHHHHHHHHHHCCCCEEEEECCCCCHHH
LIALINEYGGAIPETYGVPVEEIQKGIKSGVRKVNIDTDNRLAITAAVREALAKNPKEFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCEEHHHHHHHHHHCCCCCCC
PRHFLKPSITYMQKVCAERYVQFGTAGNASKIKQVSLETFAAKYAKGELNAISKAAAKV
CHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA