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The map label for this gene is kshA [H]

Identifier: 17232050

GI number: 17232050

Start: 5452196

End: 5453287

Strand: Reverse

Name: kshA [H]

Synonym: all4558

Alternate gene names: 17232050

Gene position: 5453287-5452196 (Counterclockwise)

Preceding gene: 17232053

Following gene: 17232049

Centisome position: 85.02

GC content: 36.9

Gene sequence:

>1092_bases
GTGAAACCTCAAATGGATGCAAACTCTCCGCATATCAAGGCTACTCATAAACCGAAAATTTTTAATAATTCAGAACGTTT
TATTGAGGGATGGTATTGGGTAATACCATCTAATAATTTAGGAATAAATGAAGTTAAATCTATCACTCTCTTAGGTAGAA
AACTAGTAATTTATCGCGGTCAAGATCAACAAGTAGCTATTTGTGATGCCTACTGTCCACACATGGGCGCTCACTTGGGT
GAAGGTACTGTTGAAGGTAATGAATTACGCTGTGCTTTCCATCACTGGAAATTTAATACTGATGGAATATGTGTGGAGAT
TCCATGTTTAGATGAACCTCTTTCCCTCAAGTTAAAAACTTGGCCGACGGTGGAGAAGTACGGGATAATTTGGATTTGGA
CTGGAGAAATACCACGAGAATCTGTACCATTCGTTCCAGAGTTAGAGTTTCAGGACTATGAAGCTGTTCTCGGTTCTAGT
TTTGTGATAAATTGCCATCCTCATCTCATGATGTTGAATACTATTGATACTCAATATTTTCAAGGAGTCCAGGTTTTAGA
TATTGGCTTTGAAAAACAGGAATTAAATCAAAATGCCATTATTTTTAGTAAATATAAACGACAACACCATGATTTGCCCT
TTAAAAAAGTCTTTCGTCCTCTATACAAAAATCCTATTTATAGTATTTGCTATTGGTATGGCAGTACATTCACTTTAACC
GTAGGAACAGACTTACGTCGTTGCTATCTTATGTTGGCTTTGCGGTTAATCCCAGGGGAACAGGTAGAAGTACAAACTAT
ATTTTTTACCAAGCAACGTAAAGGTCTATTTGGTTGGTTGTTTAATCGTTTGATGTTATGGCTGAGTAATTCTCTGGTGC
AGGAATTAATCAGTGATGAGAGAAATATTTTGCAGACTATACAGTTTAATTTAAAAAATCCCATCAAAGTAGATCAATCG
ATTATGCAGTTAATCAATCATGTGGAACTGCAAAAACCTTTGATGTGGAAGACTTGGCTGTTGGCGCGATCGCCTGAGAC
AGAGGTGAAGGAAACTCAAACGAAATGGCGAGATGAATTGACTAACGATTAA

Upstream 100 bases:

>100_bases
TGATTTACTTAATCATGAATTTTGTTATTTAAGCCAGTACTCAAAATAACTGTTTTGGGAATATATCCATGCTATTTCTA
AGGTAAATGCTTCACTGTCA

Downstream 100 bases:

>100_bases
AAAAAGATAAAAAGTAAAAAGTTATCTATCATGACTTTTTACTTTTTTCAGTCAGGCAATTGCACTCATAAAAAGAAGTG
GCAAAGCCACTTCAGATTTC

Product: hypothetical protein

Products: NA

Alternate protein names: Rieske-type oxygenase; RO [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MKPQMDANSPHIKATHKPKIFNNSERFIEGWYWVIPSNNLGINEVKSITLLGRKLVIYRGQDQQVAICDAYCPHMGAHLG
EGTVEGNELRCAFHHWKFNTDGICVEIPCLDEPLSLKLKTWPTVEKYGIIWIWTGEIPRESVPFVPELEFQDYEAVLGSS
FVINCHPHLMMLNTIDTQYFQGVQVLDIGFEKQELNQNAIIFSKYKRQHHDLPFKKVFRPLYKNPIYSICYWYGSTFTLT
VGTDLRRCYLMLALRLIPGEQVEVQTIFFTKQRKGLFGWLFNRLMLWLSNSLVQELISDERNILQTIQFNLKNPIKVDQS
IMQLINHVELQKPLMWKTWLLARSPETEVKETQTKWRDELTND

Sequences:

>Translated_363_residues
MKPQMDANSPHIKATHKPKIFNNSERFIEGWYWVIPSNNLGINEVKSITLLGRKLVIYRGQDQQVAICDAYCPHMGAHLG
EGTVEGNELRCAFHHWKFNTDGICVEIPCLDEPLSLKLKTWPTVEKYGIIWIWTGEIPRESVPFVPELEFQDYEAVLGSS
FVINCHPHLMMLNTIDTQYFQGVQVLDIGFEKQELNQNAIIFSKYKRQHHDLPFKKVFRPLYKNPIYSICYWYGSTFTLT
VGTDLRRCYLMLALRLIPGEQVEVQTIFFTKQRKGLFGWLFNRLMLWLSNSLVQELISDERNILQTIQFNLKNPIKVDQS
IMQLINHVELQKPLMWKTWLLARSPETEVKETQTKWRDELTND
>Mature_363_residues
MKPQMDANSPHIKATHKPKIFNNSERFIEGWYWVIPSNNLGINEVKSITLLGRKLVIYRGQDQQVAICDAYCPHMGAHLG
EGTVEGNELRCAFHHWKFNTDGICVEIPCLDEPLSLKLKTWPTVEKYGIIWIWTGEIPRESVPFVPELEFQDYEAVLGSS
FVINCHPHLMMLNTIDTQYFQGVQVLDIGFEKQELNQNAIIFSKYKRQHHDLPFKKVFRPLYKNPIYSICYWYGSTFTLT
VGTDLRRCYLMLALRLIPGEQVEVQTIFFTKQRKGLFGWLFNRLMLWLSNSLVQELISDERNILQTIQFNLKNPIKVDQS
IMQLINHVELQKPLMWKTWLLARSPETEVKETQTKWRDELTND

Specific function: Catalyzes the opening of ring B of 1,4-androstadiene- 3,17,-dione (ADD) and 4-androstene-3,17-dione (ADD) with concomitant aromatization of ring A. The ring B is subsequently hydroxylated to yield a catechol and then subject to meta- cleavage [H]

COG id: COG4638

COG function: function code PR; Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Rieske domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI71983709, Length=163, Percent_Identity=33.1288343558282, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI161085896, Length=163, Percent_Identity=39.2638036809816, Blast_Score=101, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017941 [H]

Pfam domain/function: PF00355 Rieske [H]

EC number: 1.14.1.- [C]

Molecular weight: Translated: 42539; Mature: 42539

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPQMDANSPHIKATHKPKIFNNSERFIEGWYWVIPSNNLGINEVKSITLLGRKLVIYRG
CCCCCCCCCCCEEECCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHEEEECCEEEEEEC
QDQQVAICDAYCPHMGAHLGEGTVEGNELRCAFHHWKFNTDGICVEIPCLDEPLSLKLKT
CCCEEEEEEHHCCHHCCCCCCCCCCCCEEEEEEEEEEECCCCEEEECCCCCCCCCEEEEC
WPTVEKYGIIWIWTGEIPRESVPFVPELEFQDYEAVLGSSFVINCHPHLMMLNTIDTQYF
CCCHHHCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCEEEEECCCCEEEEEECCHHHH
QGVQVLDIGFEKQELNQNAIIFSKYKRQHHDLPFKKVFRPLYKNPIYSICYWYGSTFTLT
CCEEEEEECCCHHHCCCCCEEEEHHHHHHCCCCHHHHHHHHHCCCHHEEEEEECCEEEEE
VGTDLRRCYLMLALRLIPGEQVEVQTIFFTKQRKGLFGWLFNRLMLWLSNSLVQELISDE
ECCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RNILQTIQFNLKNPIKVDQSIMQLINHVELQKPLMWKTWLLARSPETEVKETQTKWRDEL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHEEECCCCHHHHHHHHHHHHHC
TND
CCC
>Mature Secondary Structure
MKPQMDANSPHIKATHKPKIFNNSERFIEGWYWVIPSNNLGINEVKSITLLGRKLVIYRG
CCCCCCCCCCCEEECCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHEEEECCEEEEEEC
QDQQVAICDAYCPHMGAHLGEGTVEGNELRCAFHHWKFNTDGICVEIPCLDEPLSLKLKT
CCCEEEEEEHHCCHHCCCCCCCCCCCCEEEEEEEEEEECCCCEEEECCCCCCCCCEEEEC
WPTVEKYGIIWIWTGEIPRESVPFVPELEFQDYEAVLGSSFVINCHPHLMMLNTIDTQYF
CCCHHHCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCEEEEECCCCEEEEEECCHHHH
QGVQVLDIGFEKQELNQNAIIFSKYKRQHHDLPFKKVFRPLYKNPIYSICYWYGSTFTLT
CCEEEEEECCCHHHCCCCCEEEEHHHHHHCCCCHHHHHHHHHCCCHHEEEEEECCEEEEE
VGTDLRRCYLMLALRLIPGEQVEVQTIFFTKQRKGLFGWLFNRLMLWLSNSLVQELISDE
ECCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RNILQTIQFNLKNPIKVDQSIMQLINHVELQKPLMWKTWLLARSPETEVKETQTKWRDEL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHEEECCCCHHHHHHHHHHHHHC
TND
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA