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The map label for this gene is ywkD [H]

Identifier: 17231961

GI number: 17231961

Start: 5355345

End: 5355731

Strand: Direct

Name: ywkD [H]

Synonym: alr4469

Alternate gene names: 17231961

Gene position: 5355345-5355731 (Clockwise)

Preceding gene: 17231960

Following gene: 17231962

Centisome position: 83.5

GC content: 34.63

Gene sequence:

>387_bases
ATGAAAACCATTGGTATTCATCACGTAGCTATTATTTGTTCTGACTATGAGCGCTCAAAAAAGTTTTATGTGGAAGTTTT
AGGTTTAGGAATTATTCAAGAAACTTTTCGCGCTGCCAGAAATTCCTATAAATTAGATTTACGGATTAACGAAAATACTC
AAATTGAATTGTTTTCTTTTCCTAACCCACCCCAAAGGCCAAGCACTCCAGAAGCTTGCGGTTTAAGACATTTATCCTTT
GCGGTTGAGAGTATAGAAGAGACTGTTGCTTATTTACAATCTCATGATGTAGAGGTAGAAAATATTAGAATTGATGAGAT
TACCGGGAAGAAATTTACTTTCTTTAAAGACCCGGATGATCTGCCGTTAGAAATATATGAACATTAA

Upstream 100 bases:

>100_bases
TATACCCTTGTCCAAACCCTTTATCTTTCGTTTTCATGCGTAAGTCTGATCTAAGTTACATGAGTATGGCATTTTCTCGT
AAATCATTTAGGATTACTAT

Downstream 100 bases:

>100_bases
TAGAAAATTTTCAAACATCCTCTAAGTATAAGGGCTAAATTAAACCTAACTGCAAATTGCCTGGTTTCTTTACTCCCCTC
TCCGCGTCGGAGAGGGGCTG

Product: hypothetical protein

Products: glutathione; methylglyoxal

Alternate protein names: NA

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MKTIGIHHVAIICSDYERSKKFYVEVLGLGIIQETFRAARNSYKLDLRINENTQIELFSFPNPPQRPSTPEACGLRHLSF
AVESIEETVAYLQSHDVEVENIRIDEITGKKFTFFKDPDDLPLEIYEH

Sequences:

>Translated_128_residues
MKTIGIHHVAIICSDYERSKKFYVEVLGLGIIQETFRAARNSYKLDLRINENTQIELFSFPNPPQRPSTPEACGLRHLSF
AVESIEETVAYLQSHDVEVENIRIDEITGKKFTFFKDPDDLPLEIYEH
>Mature_128_residues
MKTIGIHHVAIICSDYERSKKFYVEVLGLGIIQETFRAARNSYKLDLRINENTQIELFSFPNPPQRPSTPEACGLRHLSF
AVESIEETVAYLQSHDVEVENIRIDEITGKKFTFFKDPDDLPLEIYEH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87081697, Length=123, Percent_Identity=57.7235772357724, Blast_Score=158, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 14814; Mature: 14814

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIGIHHVAIICSDYERSKKFYVEVLGLGIIQETFRAARNSYKLDLRINENTQIELFSF
CCCCCEEEEEEEECCCHHHHHEEHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEC
PNPPQRPSTPEACGLRHLSFAVESIEETVAYLQSHDVEVENIRIDEITGKKFTFFKDPDD
CCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCEEEEECCCCC
LPLEIYEH
CCEEEECC
>Mature Secondary Structure
MKTIGIHHVAIICSDYERSKKFYVEVLGLGIIQETFRAARNSYKLDLRINENTQIELFSF
CCCCCEEEEEEEECCCHHHHHEEHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEC
PNPPQRPSTPEACGLRHLSFAVESIEETVAYLQSHDVEVENIRIDEITGKKFTFFKDPDD
CCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCEEEEECCCCC
LPLEIYEH
CCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]