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The map label for this gene is ahpC [C]

Identifier: 17231896

GI number: 17231896

Start: 5280720

End: 5281358

Strand: Direct

Name: ahpC [C]

Synonym: alr4404

Alternate gene names: 17231896

Gene position: 5280720-5281358 (Clockwise)

Preceding gene: 17231890

Following gene: 17231897

Centisome position: 82.33

GC content: 45.85

Gene sequence:

>639_bases
ATGGCTCTCCGTCTTGGTGATACAGTACCCAACTTTACACAAGCGTCTACACATGGCGACATAGATTTTTACGCATGGGC
TGGTGATAGCTGGGTTGTGCTGTTTTCTCACCCTGCTGACTATACCCCAGTTTGTACAACTGAATTAGGAACAGTTGCCA
AACTGAAACCAGAATTTGACAAGCGCAATGTGAAAGCGATCGCTCTTAGCGTTGATGATGTAGAATCTCACAACGGTTGG
GTAGGCGACATTGAAGAAACTCAAAGCACCACACTCAACTACCCCATTTTGGCAGATGCAGATCGTAAAGTTTCTGACCT
TTACGACATGATTCATCCTAATGCGAATGCAGCTGTAACAGTGCGTTCAGTATTTGTGATTGATCCCAACAAAAAACTCC
GTCTCACCTTCACCTATCCCCCCAGCACCGGACGTAACTTTGATGAACTGTTGCGAGTCATCGATTCCTTGCAACTCACC
GACAACTACAGCGTCGCTACCCCAGCCGACTGGAAAGATGGCGATAAGGTTGTCATCGTTCCCTCCCTCAAAGACCCCGA
AGTCTTAAAAGAAAAATTCCCTAAAGGTTACGAAGTAGTCAAACCCTATTTGCGGTTAACTCCTCAACCTAACAAGTAA

Upstream 100 bases:

>100_bases
TTTGTTAAAAACCACTAAAAGCCGATGGGGAAACCGATGTTGTTTTGCCTTTATGGCAAGATAGAATACATAGGCCTTAC
TTAACTACAGGGAATCTCTT

Downstream 100 bases:

>100_bases
TGATTGCTGAGTGAGAATAACTACTCAATATTGAGTAGATAAATTTTTAAATCAATTCGTTTACAAGACGCAAAGCTTTA
TCTTTGCGTTTTTTTGTATT

Product: AhpC/TSA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MALRLGDTVPNFTQASTHGDIDFYAWAGDSWVVLFSHPADYTPVCTTELGTVAKLKPEFDKRNVKAIALSVDDVESHNGW
VGDIEETQSTTLNYPILADADRKVSDLYDMIHPNANAAVTVRSVFVIDPNKKLRLTFTYPPSTGRNFDELLRVIDSLQLT
DNYSVATPADWKDGDKVVIVPSLKDPEVLKEKFPKGYEVVKPYLRLTPQPNK

Sequences:

>Translated_212_residues
MALRLGDTVPNFTQASTHGDIDFYAWAGDSWVVLFSHPADYTPVCTTELGTVAKLKPEFDKRNVKAIALSVDDVESHNGW
VGDIEETQSTTLNYPILADADRKVSDLYDMIHPNANAAVTVRSVFVIDPNKKLRLTFTYPPSTGRNFDELLRVIDSLQLT
DNYSVATPADWKDGDKVVIVPSLKDPEVLKEKFPKGYEVVKPYLRLTPQPNK
>Mature_211_residues
ALRLGDTVPNFTQASTHGDIDFYAWAGDSWVVLFSHPADYTPVCTTELGTVAKLKPEFDKRNVKAIALSVDDVESHNGWV
GDIEETQSTTLNYPILADADRKVSDLYDMIHPNANAAVTVRSVFVIDPNKKLRLTFTYPPSTGRNFDELLRVIDSLQLTD
NYSVATPADWKDGDKVVIVPSLKDPEVLKEKFPKGYEVVKPYLRLTPQPNK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=222, Percent_Identity=51.8018018018018, Blast_Score=213, Evalue=7e-56,
Organism=Homo sapiens, GI4505591, Length=195, Percent_Identity=29.7435897435897, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI32455266, Length=195, Percent_Identity=29.7435897435897, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI32455264, Length=195, Percent_Identity=29.7435897435897, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI32189392, Length=197, Percent_Identity=30.4568527918782, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI5453549, Length=150, Percent_Identity=30, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI32483377, Length=166, Percent_Identity=30.1204819277108, Blast_Score=78, Evalue=5e-15,
Organism=Homo sapiens, GI5802974, Length=166, Percent_Identity=30.1204819277108, Blast_Score=78, Evalue=5e-15,
Organism=Escherichia coli, GI1786822, Length=154, Percent_Identity=31.1688311688312, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25153706, Length=199, Percent_Identity=41.7085427135678, Blast_Score=167, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI193204376, Length=188, Percent_Identity=30.8510638297872, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32565831, Length=188, Percent_Identity=30.8510638297872, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17554494, Length=144, Percent_Identity=31.25, Blast_Score=88, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6319407, Length=212, Percent_Identity=54.7169811320755, Blast_Score=223, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6323613, Length=156, Percent_Identity=28.8461538461538, Blast_Score=69, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6320661, Length=156, Percent_Identity=26.9230769230769, Blast_Score=62, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24581278, Length=219, Percent_Identity=54.7945205479452, Blast_Score=235, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24652436, Length=209, Percent_Identity=51.6746411483254, Blast_Score=197, Evalue=3e-51,
Organism=Drosophila melanogaster, GI24652434, Length=209, Percent_Identity=51.1961722488038, Blast_Score=197, Evalue=4e-51,
Organism=Drosophila melanogaster, GI17975518, Length=209, Percent_Identity=51.1961722488038, Blast_Score=196, Evalue=7e-51,
Organism=Drosophila melanogaster, GI17157991, Length=175, Percent_Identity=31.4285714285714, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24641739, Length=175, Percent_Identity=31.4285714285714, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17738015, Length=142, Percent_Identity=33.8028169014084, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI21357347, Length=193, Percent_Identity=26.9430051813472, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24656348, Length=150, Percent_Identity=30, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17864676, Length=150, Percent_Identity=30, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23698; Mature: 23567

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALRLGDTVPNFTQASTHGDIDFYAWAGDSWVVLFSHPADYTPVCTTELGTVAKLKPEFD
CEEECCCCCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCCCCEECCCCCCEEECCCCCC
KRNVKAIALSVDDVESHNGWVGDIEETQSTTLNYPILADADRKVSDLYDMIHPNANAAVT
CCCEEEEEEEECCCCCCCCEECCCCCCCCCEECCCEEECCCCHHHHHHHHHCCCCCCEEE
VRSVFVIDPNKKLRLTFTYPPSTGRNFDELLRVIDSLQLTDNYSVATPADWKDGDKVVIV
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHEEECCCCCCCCCCCCCCCCEEEEE
PSLKDPEVLKEKFPKGYEVVKPYLRLTPQPNK
ECCCCHHHHHHHCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ALRLGDTVPNFTQASTHGDIDFYAWAGDSWVVLFSHPADYTPVCTTELGTVAKLKPEFD
EEECCCCCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCCCCEECCCCCCEEECCCCCC
KRNVKAIALSVDDVESHNGWVGDIEETQSTTLNYPILADADRKVSDLYDMIHPNANAAVT
CCCEEEEEEEECCCCCCCCEECCCCCCCCCEECCCEEECCCCHHHHHHHHHCCCCCCEEE
VRSVFVIDPNKKLRLTFTYPPSTGRNFDELLRVIDSLQLTDNYSVATPADWKDGDKVVIV
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHEEECCCCCCCCCCCCCCCCEEEEE
PSLKDPEVLKEKFPKGYEVVKPYLRLTPQPNK
ECCCCHHHHHHHCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]