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The map label for this gene is mraY

Identifier: 17231808

GI number: 17231808

Start: 5169780

End: 5170889

Strand: Reverse

Name: mraY

Synonym: all4316

Alternate gene names: 17231808

Gene position: 5170889-5169780 (Counterclockwise)

Preceding gene: 17231809

Following gene: 17231807

Centisome position: 80.62

GC content: 46.76

Gene sequence:

>1110_bases
GTGGACGCTAAATTATCGCCTAATCAAGGATTAAATATTTCTGGTATTGGTCTAGCTTCTTCCTTAGCCGCCGGGCTAGG
CATAGCAGCTTTAACTTTGGATTGGATGGCAAACAGAAATCCCTGGCAAGGTACATCGCTGACCTTGCCCCTGTTGCTAT
GTACTATTGCTTCAGCTATTGCAGGTTACTTTGTAGTGCCTCTACTGCAAGCACTGAAAACTGGGCAAATCATCCGTGAA
GATGGCCCTCAAGCCCATTTGAAAAAAGCCGGCACACCCACAATGGGGGGGATATTTTTTATTCCTGTTGCCGTGGTAGG
TGCTTGTGTACTGTCTAACTTTGCCACAGAAGTACTTGCAGTCTCGGCTCTCACCCTCAGTTATGGGCTAATTGGTTGGA
TTGACGATTGGCAAATTTTGCGCCGCAAGTCCAATAAGGGTATATCCCCCCGGATGAAATTGGCTTTGCAAATCGGTTTT
GCAGCAGCCTTTTGTTTATGGTTAATGTTTAATCAACCTGCTAATATTACGAGTATTGCTTTACCCTGGGTAAGCTTTGC
CCTACCTTTGGGATTTTTATTCTGGCCTTTGGCTGGCTTTGTCCTCGTGGCAGAGAGTAATGCAACTAATTTAACTGATG
GTATTGATGGATTAGCCGGAGGAACTGTAGCGATCGCCTTACTCGCATTAGGTGCTATCGTTGCCCCAACATCCCCCGCA
TTAATGGTTTTCTGTGCAGCTTTAAGTGGTAGTTGCTTAGGTTTCTTAGCTCACAACCGCAACCCAGCCAGGGTATTTAT
GGGTGATACAGGTTCCCTAGCACTAGGAGGTGCTTTAGCGGCTGTGGCATTACTAACTAACAGTTTAGTAGCCCTGTTTA
TCCTCAGTGGCATCTTCTTCGTCGAAACCCTTTCTGTAATGGCACAAGTAAGCTATTACAAAGCCACCAAAGGCCCCGAT
GGGAAAGGCAAGCGCCTCTTGAAAATGGCTCCTCTGCACCACCATTTAGAATTATCAGGCTGGTCAGAATTACAGGTAGT
TAGCTCATTTTACGTGATAGCTGCCATCTTAGCCGCCATCTGTCTGGCGATCGCCTCCGGTGGAGCATAG

Upstream 100 bases:

>100_bases
TATCACCATAGACGAAGATTAGTCTTTTGAGACTGGGACTCTGTTATATATAGTCCCTATAATTCAGTTTTATTAAAGTG
TGGAGTGAAGGGAAACTTTT

Downstream 100 bases:

>100_bases
CTCATCGCCCCATTCTGAATATTTCACAAAATTAATCATCAACAAGAAATAACTCTCTGCATATACAGAGGGTTATTTTT
TGTTATTCGGGTATTTTGGG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MDAKLSPNQGLNISGIGLASSLAAGLGIAALTLDWMANRNPWQGTSLTLPLLLCTIASAIAGYFVVPLLQALKTGQIIRE
DGPQAHLKKAGTPTMGGIFFIPVAVVGACVLSNFATEVLAVSALTLSYGLIGWIDDWQILRRKSNKGISPRMKLALQIGF
AAAFCLWLMFNQPANITSIALPWVSFALPLGFLFWPLAGFVLVAESNATNLTDGIDGLAGGTVAIALLALGAIVAPTSPA
LMVFCAALSGSCLGFLAHNRNPARVFMGDTGSLALGGALAAVALLTNSLVALFILSGIFFVETLSVMAQVSYYKATKGPD
GKGKRLLKMAPLHHHLELSGWSELQVVSSFYVIAAILAAICLAIASGGA

Sequences:

>Translated_369_residues
MDAKLSPNQGLNISGIGLASSLAAGLGIAALTLDWMANRNPWQGTSLTLPLLLCTIASAIAGYFVVPLLQALKTGQIIRE
DGPQAHLKKAGTPTMGGIFFIPVAVVGACVLSNFATEVLAVSALTLSYGLIGWIDDWQILRRKSNKGISPRMKLALQIGF
AAAFCLWLMFNQPANITSIALPWVSFALPLGFLFWPLAGFVLVAESNATNLTDGIDGLAGGTVAIALLALGAIVAPTSPA
LMVFCAALSGSCLGFLAHNRNPARVFMGDTGSLALGGALAAVALLTNSLVALFILSGIFFVETLSVMAQVSYYKATKGPD
GKGKRLLKMAPLHHHLELSGWSELQVVSSFYVIAAILAAICLAIASGGA
>Mature_369_residues
MDAKLSPNQGLNISGIGLASSLAAGLGIAALTLDWMANRNPWQGTSLTLPLLLCTIASAIAGYFVVPLLQALKTGQIIRE
DGPQAHLKKAGTPTMGGIFFIPVAVVGACVLSNFATEVLAVSALTLSYGLIGWIDDWQILRRKSNKGISPRMKLALQIGF
AAAFCLWLMFNQPANITSIALPWVSFALPLGFLFWPLAGFVLVAESNATNLTDGIDGLAGGTVAIALLALGAIVAPTSPA
LMVFCAALSGSCLGFLAHNRNPARVFMGDTGSLALGGALAAVALLTNSLVALFILSGIFFVETLSVMAQVSYYKATKGPD
GKGKRLLKMAPLHHHLELSGWSELQVVSSFYVIAAILAAICLAIASGGA

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=317, Percent_Identity=40.6940063091483, Blast_Score=191, Evalue=5e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_NOSS1 (Q8YP83)

Other databases:

- EMBL:   BA000019
- PIR:   AE2345
- RefSeq:   NP_488356.1
- STRING:   Q8YP83
- GeneID:   1107918
- GenomeReviews:   BA000019_GR
- KEGG:   ana:all4316
- NMPDR:   fig|103690.1.peg.4623
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- BioCyc:   NSP103690:ALL4316-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 38336; Mature: 38336

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x13b92c88)-; HASH(0x1472d74c)-; HASH(0x144289dc)-; HASH(0x147575b0)-; HASH(0x1474ab60)-; HASH(0x13ffb98c)-; HASH(0x14072570)-; HASH(0x1472d584)-; HASH(0x14757640)-; HASH(0x1474a9b0)-;

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAKLSPNQGLNISGIGLASSLAAGLGIAALTLDWMANRNPWQGTSLTLPLLLCTIASAI
CCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
AGYFVVPLLQALKTGQIIREDGPQAHLKKAGTPTMGGIFFIPVAVVGACVLSNFATEVLA
HHHHHHHHHHHHHCCCHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VSALTLSYGLIGWIDDWQILRRKSNKGISPRMKLALQIGFAAAFCLWLMFNQPANITSIA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LPWVSFALPLGFLFWPLAGFVLVAESNATNLTDGIDGLAGGTVAIALLALGAIVAPTSPA
HHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHH
LMVFCAALSGSCLGFLAHNRNPARVFMGDTGSLALGGALAAVALLTNSLVALFILSGIFF
HHHHHHHHCCCHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VETLSVMAQVSYYKATKGPDGKGKRLLKMAPLHHHLELSGWSELQVVSSFYVIAAILAAI
HHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHEEECCCCHHHHHHHHHHHHHHHHHHH
CLAIASGGA
HHHHHCCCH
>Mature Secondary Structure
MDAKLSPNQGLNISGIGLASSLAAGLGIAALTLDWMANRNPWQGTSLTLPLLLCTIASAI
CCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
AGYFVVPLLQALKTGQIIREDGPQAHLKKAGTPTMGGIFFIPVAVVGACVLSNFATEVLA
HHHHHHHHHHHHHCCCHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VSALTLSYGLIGWIDDWQILRRKSNKGISPRMKLALQIGFAAAFCLWLMFNQPANITSIA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LPWVSFALPLGFLFWPLAGFVLVAESNATNLTDGIDGLAGGTVAIALLALGAIVAPTSPA
HHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHH
LMVFCAALSGSCLGFLAHNRNPARVFMGDTGSLALGGALAAVALLTNSLVALFILSGIFF
HHHHHHHHCCCHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VETLSVMAQVSYYKATKGPDGKGKRLLKMAPLHHHLELSGWSELQVVSSFYVIAAILAAI
HHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHEEECCCCHHHHHHHHHHHHHHHHHHH
CLAIASGGA
HHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11759840