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The map label for this gene is kdpE [H]

Identifier: 17231804

GI number: 17231804

Start: 5166997

End: 5167767

Strand: Reverse

Name: kdpE [H]

Synonym: all4312

Alternate gene names: 17231804

Gene position: 5167767-5166997 (Counterclockwise)

Preceding gene: 17231807

Following gene: 17231799

Centisome position: 80.57

GC content: 47.21

Gene sequence:

>771_bases
GTGGGTTCGGTTTGTATTGAAATCGTTGAGGGGAATCCCCATCTGAGGTCGTTGCTGGGTTGGCACTTGCAACAATTGGA
ATACCGTGTGCATCAAGCCGCCAGCATATATCAAGCAAGGGAAGCCTTTTTGAGCCATCAGCCAACTCTAGTGATTCTGG
ATGCTGATTTGCCAGATGGTGACGGTATTGAATTTTGCCGTTGGCTGCATCGTCAGCAACAGCCGCTAATTCTCATGTTA
TCTGCTCGGACTAATGAGGCTGATATCGTTGCCGGGTTGAAGGCGGGAGCTGATGATTACTTGAGCAAACCATTTGGGAT
GCAGGAGTTTTTGGCTAGGGTAGAGGCATTAATCCGCCGCAAGCGCACACCTACTGCTCCTGCTTATTTGGATTATGGTA
CTTTGCAAATCGATTTAGTCCAACGCCGTGTACGATTCCAAGGGGAGTTTATCGACCTGACTCCACAGGAATTTAGTTTG
TTGTACGTTTTGGCGCAAGCTGGTGGAGTACCTTTGAGCCGATCAGAGTTGCTACGTCGTGCGTGGCCTGACGCTATCGA
CAATCCGCGTACCATTGACACTCATGTTCTATCGTTACGTAAAAAAGTAGAACTTGATCCCCGCCAACCTAGCCTCATTC
AGACTATCCGCAATGTTGGATACCGATTTAACATGGAAATTTTGAATGCTAATCCTCCACAAACACAAGCAAAGTTAACA
AAAGAAAGATTTAGCAACCAACGCTCAACTCTAAGTGGGCAGAGGGTGTAG

Upstream 100 bases:

>100_bases
AAAACGTAGAGGTAATTGTGGCTAGAGTAACAAAGACTACAAAACCTTGGGCATGGGCTTGTTACTTTGAAATTCATCGA
CGCTAAGGGGTCTTGCCGCC

Downstream 100 bases:

>100_bases
AGGAGGCAGAGGGAGGAAAAATAATGATTTTTACTCCTAACTCAGCACTAATGACTATTGATTATTAACTTAGTTCCATT
CTTCATCGGCTTGGTTTTCG

Product: two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MGSVCIEIVEGNPHLRSLLGWHLQQLEYRVHQAASIYQAREAFLSHQPTLVILDADLPDGDGIEFCRWLHRQQQPLILML
SARTNEADIVAGLKAGADDYLSKPFGMQEFLARVEALIRRKRTPTAPAYLDYGTLQIDLVQRRVRFQGEFIDLTPQEFSL
LYVLAQAGGVPLSRSELLRRAWPDAIDNPRTIDTHVLSLRKKVELDPRQPSLIQTIRNVGYRFNMEILNANPPQTQAKLT
KERFSNQRSTLSGQRV

Sequences:

>Translated_256_residues
MGSVCIEIVEGNPHLRSLLGWHLQQLEYRVHQAASIYQAREAFLSHQPTLVILDADLPDGDGIEFCRWLHRQQQPLILML
SARTNEADIVAGLKAGADDYLSKPFGMQEFLARVEALIRRKRTPTAPAYLDYGTLQIDLVQRRVRFQGEFIDLTPQEFSL
LYVLAQAGGVPLSRSELLRRAWPDAIDNPRTIDTHVLSLRKKVELDPRQPSLIQTIRNVGYRFNMEILNANPPQTQAKLT
KERFSNQRSTLSGQRV
>Mature_255_residues
GSVCIEIVEGNPHLRSLLGWHLQQLEYRVHQAASIYQAREAFLSHQPTLVILDADLPDGDGIEFCRWLHRQQQPLILMLS
ARTNEADIVAGLKAGADDYLSKPFGMQEFLARVEALIRRKRTPTAPAYLDYGTLQIDLVQRRVRFQGEFIDLTPQEFSLL
YVLAQAGGVPLSRSELLRRAWPDAIDNPRTIDTHVLSLRKKVELDPRQPSLIQTIRNVGYRFNMEILNANPPQTQAKLTK
ERFSNQRSTLSGQRV

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=39.0909090909091, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=35.3982300884956, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=34.6320346320346, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=34.5454545454545, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=32.7354260089686, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786784, Length=216, Percent_Identity=35.6481481481481, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=33.9449541284404, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790860, Length=219, Percent_Identity=33.7899543378995, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789402, Length=202, Percent_Identity=35.1485148514851, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082012, Length=207, Percent_Identity=34.2995169082126, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI2367329, Length=173, Percent_Identity=35.2601156069364, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=29.3859649122807, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787229, Length=209, Percent_Identity=30.1435406698565, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=30.3418803418803, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 29180; Mature: 29049

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSVCIEIVEGNPHLRSLLGWHLQQLEYRVHQAASIYQAREAFLSHQPTLVILDADLPDG
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
DGIEFCRWLHRQQQPLILMLSARTNEADIVAGLKAGADDYLSKPFGMQEFLARVEALIRR
CCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHH
KRTPTAPAYLDYGTLQIDLVQRRVRFQGEFIDLTPQEFSLLYVLAQAGGVPLSRSELLRR
CCCCCCCCEECCCCEEHHHHHHHHHHCCCEEECCHHHHHHHHHEECCCCCCCCHHHHHHH
AWPDAIDNPRTIDTHVLSLRKKVELDPRQPSLIQTIRNVGYRFNMEILNANPPQTQAKLT
HCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEEEEEEECCCCCHHHHHHH
KERFSNQRSTLSGQRV
HHHHCCHHHCCCCCCC
>Mature Secondary Structure 
GSVCIEIVEGNPHLRSLLGWHLQQLEYRVHQAASIYQAREAFLSHQPTLVILDADLPDG
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
DGIEFCRWLHRQQQPLILMLSARTNEADIVAGLKAGADDYLSKPFGMQEFLARVEALIRR
CCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHH
KRTPTAPAYLDYGTLQIDLVQRRVRFQGEFIDLTPQEFSLLYVLAQAGGVPLSRSELLRR
CCCCCCCCEECCCCEEHHHHHHHHHHCCCEEECCHHHHHHHHHEECCCCCCCCHHHHHHH
AWPDAIDNPRTIDTHVLSLRKKVELDPRQPSLIQTIRNVGYRFNMEILNANPPQTQAKLT
HCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEEEEEEECCCCCHHHHHHH
KERFSNQRSTLSGQRV
HHHHCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]