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The map label for this gene is glyS

Identifier: 17231603

GI number: 17231603

Start: 4952980

End: 4955130

Strand: Direct

Name: glyS

Synonym: alr4111

Alternate gene names: 17231603

Gene position: 4952980-4955130 (Clockwise)

Preceding gene: 17231600

Following gene: 17231604

Centisome position: 77.22

GC content: 44.96

Gene sequence:

>2151_bases
ATGCCTGGGTTTTTATTGGAAGTTGGAACAGAAGAATTACCTGCAAGCTTTCTCGGTGGTGCGATCGCTCAGTGGCGATC
GCGGATTCCCCAGAGTTTAGCAGCTAATAGCCTCACCAGTGAATCTGTAGAGGTCTACGGGACTCCCCGGCGTTTGGCAG
TACTCATCACAGGTTTACCATCCCAACAGCCAGATCGGGAAGAGGAAATCAAAGGCCCACCCGCCCAAGCAGCTTTTAAA
GATGGTCAACCAACTCCAGCCGCCGTAGGTTTTGCTAAAAAGCAAGGGGTAGAACTAGAGGCGTTAGAGGTACGCCCCAC
GGATAAGGGGGAATTTGTCTTTATTCAGAAAAAAACACCCGGTCGTCCTGTGGCAGACATTCTAACCGAACTTGTCCCTC
AATGGATTTATAGCCTAGAAGGTAAGCGGTTGATGCGTTGGGGTGATGGGGATGTGAGATTTTCCCGTCCCATTCGCTGG
TTAGTTGCTTTATTAGATGAGGCGATTTTGCCCCTGGAATTGGTGAATGGTTCCTTGACGGTGAAGAGCGATCGCATTTC
TTACGGTCATCGGGTTTTACATCCCGCACCAATTACAATTCAGAAAGCGGGTGATTACGTCAATACGCTGCGTGATGGTT
ATGTGACTGTAAATGCTAAGGAACGGACGACGACAATTAAAGAGCAAGTAGCCGCTACGGTGCAAAAATTAGGCGGTTAT
ACAGAAATTTACCCAGATTTATTAGAGGAAGTTACTAACTTAGTAGAATGGCCTTCCCCAGTGGTTGGTAAATTTGAAGA
AGAATTTTTAAACTTACCGACGGAAGTGACGACAACAGTCATGGTGAGTCACCAACGTTATTTTCCTGTATTCAAGACTG
GGGATCATAAAGAACTTTTACCTTATTTCATCACCGTTTCTAACGGCGACCCCACTAAATCAGAAGTGATTGCGGTTGGT
AATGAAAGAGTGATTCGGGCAAGATTAGCAGATGGTCAGTTTTTCTATAAAACAGATTTATCCAAGAGTTTAGAAAGTTA
TTTACCCCAATTAGAAACAGTCACTTTTCAAGAAGACCTTGGTTCTTTACGTGGCAAGGTAGAGAGAATTGTTAAGGTTG
CTGCACAGATTAGTAGCCAACTGCAATTAGGGGAAGGCGATCGCCAAAACAACCAAAGAGCCGCTTTATTATGTAAAGCT
GATTTAGTCACCCAAATGGTGTTTGAATTCCCAGAACTACAGGGAATTATGGGACAAAAGTATGCTGTAGCTAGTGGAGA
AAGTCCAGAAGTATCCACGGCAATTGTTGAACATTATTTACCACGGGGAGCCGATGACATCTTACCCCAAACCCTCACAG
GTCAAGTTGTGGGTTTGGCAGATAGACTCGATACCTTAGTGAGTATCTTTGGCTTGGGGTTAATTCCCACAGGTTCATCT
GACCCCTTTGCTTTGCGCCGCGCCGCTAACGCTGTAGTTAACATTACTTGGGCTGCTAATTTACAAATCAACTTAGCTAG
TTTACTGGCACAAACAGTAGCCGAATTTGCTGCCCAATACAATAAAGACCAAGCGCCATTAATTACAGCCTTAAATGAAT
TCTTTTTGCAACGTATTCGCACCTTATTACAAGAAGAGAAACAAATTGACTACGACTTAGTAAATGCAGTATTGGGAGAG
AATGACCCAGAATATACAGAACGGGCATTACAGGATTTACTAGATGTGCGCGATCGCGCCCTCTATCTACAACAAATCCG
CCGCGACGGTACACTAGATAAAATCTACGAAACCGTGAACCGTTCCACACGCCTAGCAGCCCAAGGTGATTTAGATACCC
AACAGCTAGACCCCACATCTGTAGTGCGTCCTGAATTGTTCCAAAAGCCTTCCGAATCAGATTTTTATGATGCTTTGGTT
AAACTAGTACCCCAAACGCAAGCAGCACAAGAGTCACGCAACTATCAATTGTTAGTAGCGGGGTTGGTGGAGATTGCGCC
TACGGTGAGTAACTTCTTTGATGGAGCAGATAGCGTTTTAGTGATTGACCCCGACCCAGAAATCAAGCGCAATCGCCTAA
ATATCCTGGGATTATTGCGGAATCATGCCCGTGTGTTAGCTGACTTTGGGGCGATCGTGAAAAATCTGTAG

Upstream 100 bases:

>100_bases
ACACCCCTAAACCCCCACACCCTTACACCCTAAGCCTGACGGCAAGGTAAACTGTTGGAATTGATAAAGTTAAGCTACGC
AAAGTTAGAAACAGAATCCT

Downstream 100 bases:

>100_bases
TATAAAGCAATAAAAAGTGGTGTAATTTTTGCCCATTAAGCGCTACCATTATGAGTGCTTAACCAGGGAACTCTGCCACA
GTCTATGTCCAAAGCCCATG

Product: glycyl-tRNA synthetase subunit beta

Products: NA

Alternate protein names: Glycine--tRNA ligase beta subunit; GlyRS

Number of amino acids: Translated: 716; Mature: 715

Protein sequence:

>716_residues
MPGFLLEVGTEELPASFLGGAIAQWRSRIPQSLAANSLTSESVEVYGTPRRLAVLITGLPSQQPDREEEIKGPPAQAAFK
DGQPTPAAVGFAKKQGVELEALEVRPTDKGEFVFIQKKTPGRPVADILTELVPQWIYSLEGKRLMRWGDGDVRFSRPIRW
LVALLDEAILPLELVNGSLTVKSDRISYGHRVLHPAPITIQKAGDYVNTLRDGYVTVNAKERTTTIKEQVAATVQKLGGY
TEIYPDLLEEVTNLVEWPSPVVGKFEEEFLNLPTEVTTTVMVSHQRYFPVFKTGDHKELLPYFITVSNGDPTKSEVIAVG
NERVIRARLADGQFFYKTDLSKSLESYLPQLETVTFQEDLGSLRGKVERIVKVAAQISSQLQLGEGDRQNNQRAALLCKA
DLVTQMVFEFPELQGIMGQKYAVASGESPEVSTAIVEHYLPRGADDILPQTLTGQVVGLADRLDTLVSIFGLGLIPTGSS
DPFALRRAANAVVNITWAANLQINLASLLAQTVAEFAAQYNKDQAPLITALNEFFLQRIRTLLQEEKQIDYDLVNAVLGE
NDPEYTERALQDLLDVRDRALYLQQIRRDGTLDKIYETVNRSTRLAAQGDLDTQQLDPTSVVRPELFQKPSESDFYDALV
KLVPQTQAAQESRNYQLLVAGLVEIAPTVSNFFDGADSVLVIDPDPEIKRNRLNILGLLRNHARVLADFGAIVKNL

Sequences:

>Translated_716_residues
MPGFLLEVGTEELPASFLGGAIAQWRSRIPQSLAANSLTSESVEVYGTPRRLAVLITGLPSQQPDREEEIKGPPAQAAFK
DGQPTPAAVGFAKKQGVELEALEVRPTDKGEFVFIQKKTPGRPVADILTELVPQWIYSLEGKRLMRWGDGDVRFSRPIRW
LVALLDEAILPLELVNGSLTVKSDRISYGHRVLHPAPITIQKAGDYVNTLRDGYVTVNAKERTTTIKEQVAATVQKLGGY
TEIYPDLLEEVTNLVEWPSPVVGKFEEEFLNLPTEVTTTVMVSHQRYFPVFKTGDHKELLPYFITVSNGDPTKSEVIAVG
NERVIRARLADGQFFYKTDLSKSLESYLPQLETVTFQEDLGSLRGKVERIVKVAAQISSQLQLGEGDRQNNQRAALLCKA
DLVTQMVFEFPELQGIMGQKYAVASGESPEVSTAIVEHYLPRGADDILPQTLTGQVVGLADRLDTLVSIFGLGLIPTGSS
DPFALRRAANAVVNITWAANLQINLASLLAQTVAEFAAQYNKDQAPLITALNEFFLQRIRTLLQEEKQIDYDLVNAVLGE
NDPEYTERALQDLLDVRDRALYLQQIRRDGTLDKIYETVNRSTRLAAQGDLDTQQLDPTSVVRPELFQKPSESDFYDALV
KLVPQTQAAQESRNYQLLVAGLVEIAPTVSNFFDGADSVLVIDPDPEIKRNRLNILGLLRNHARVLADFGAIVKNL
>Mature_715_residues
PGFLLEVGTEELPASFLGGAIAQWRSRIPQSLAANSLTSESVEVYGTPRRLAVLITGLPSQQPDREEEIKGPPAQAAFKD
GQPTPAAVGFAKKQGVELEALEVRPTDKGEFVFIQKKTPGRPVADILTELVPQWIYSLEGKRLMRWGDGDVRFSRPIRWL
VALLDEAILPLELVNGSLTVKSDRISYGHRVLHPAPITIQKAGDYVNTLRDGYVTVNAKERTTTIKEQVAATVQKLGGYT
EIYPDLLEEVTNLVEWPSPVVGKFEEEFLNLPTEVTTTVMVSHQRYFPVFKTGDHKELLPYFITVSNGDPTKSEVIAVGN
ERVIRARLADGQFFYKTDLSKSLESYLPQLETVTFQEDLGSLRGKVERIVKVAAQISSQLQLGEGDRQNNQRAALLCKAD
LVTQMVFEFPELQGIMGQKYAVASGESPEVSTAIVEHYLPRGADDILPQTLTGQVVGLADRLDTLVSIFGLGLIPTGSSD
PFALRRAANAVVNITWAANLQINLASLLAQTVAEFAAQYNKDQAPLITALNEFFLQRIRTLLQEEKQIDYDLVNAVLGEN
DPEYTERALQDLLDVRDRALYLQQIRRDGTLDKIYETVNRSTRLAAQGDLDTQQLDPTSVVRPELFQKPSESDFYDALVK
LVPQTQAAQESRNYQLLVAGLVEIAPTVSNFFDGADSVLVIDPDPEIKRNRLNILGLLRNHARVLADFGAIVKNL

Specific function: Unknown

COG id: COG0751

COG function: function code J; Glycyl-tRNA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1789982, Length=703, Percent_Identity=35.5618776671408, Blast_Score=383, Evalue=1e-107,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 400 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYGB_NOSS1 (Q8YPT0)

Other databases:

- EMBL:   BA000019
- PIR:   AH2319
- RefSeq:   NP_488151.1
- ProteinModelPortal:   Q8YPT0
- STRING:   Q8YPT0
- GeneID:   1107713
- GenomeReviews:   BA000019_GR
- KEGG:   ana:alr4111
- NMPDR:   fig|103690.1.peg.4418
- eggNOG:   COG0751
- HOGENOM:   HBG586599
- OMA:   SNITYGH
- PhylomeDB:   Q8YPT0
- ProtClustDB:   PRK01233
- BioCyc:   NSP103690:ALR4111-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00255
- InterPro:   IPR006194
- InterPro:   IPR015944
- InterPro:   IPR002311
- PRINTS:   PR01045
- TIGRFAMs:   TIGR00211

Pfam domain/function: PF02092 tRNA_synt_2f

EC number: =6.1.1.14

Molecular weight: Translated: 79347; Mature: 79216

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50861 AA_TRNA_LIGASE_II_GLYAB; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGFLLEVGTEELPASFLGGAIAQWRSRIPQSLAANSLTSESVEVYGTPRRLAVLITGLP
CCCCEEECCCHHCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCEEEECCCCEEEEEEECCC
SQQPDREEEIKGPPAQAAFKDGQPTPAAVGFAKKQGVELEALEVRPTDKGEFVFIQKKTP
CCCCCCHHHCCCCCCCCCCCCCCCCCHHHCHHHHCCCCEEEEEECCCCCCCEEEEECCCC
GRPVADILTELVPQWIYSLEGKRLMRWGDGDVRFSRPIRWLVALLDEAILPLELVNGSLT
CCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHEECCEEE
VKSDRISYGHRVLHPAPITIQKAGDYVNTLRDGYVTVNAKERTTTIKEQVAATVQKLGGY
EECCCCCCCCEEECCCCEEEECCCCHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHCCH
TEIYPDLLEEVTNLVEWPSPVVGKFEEEFLNLPTEVTTTVMVSHQRYFPVFKTGDHKELL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHEEEECCCCCCCEECCCCCCCC
PYFITVSNGDPTKSEVIAVGNERVIRARLADGQFFYKTDLSKSLESYLPQLETVTFQEDL
EEEEEECCCCCCCCCEEEECCCEEEEEEECCCCEEEHHHHHHHHHHHCCHHHEEHHHHHH
GSLRGKVERIVKVAAQISSQLQLGEGDRQNNQRAALLCKADLVTQMVFEFPELQGIMGQK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHCHHHHHHCCCC
YAVASGESPEVSTAIVEHYLPRGADDILPQTLTGQVVGLADRLDTLVSIFGLGLIPTGSS
EEECCCCCCCHHHHHHHHHCCCCCHHHCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCCCC
DPFALRRAANAVVNITWAANLQINLASLLAQTVAEFAAQYNKDQAPLITALNEFFLQRIR
CCHHHHHHCCEEEEEEEEECCEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
TLLQEEKQIDYDLVNAVLGENDPEYTERALQDLLDVRDRALYLQQIRRDGTLDKIYETVN
HHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
RSTRLAAQGDLDTQQLDPTSVVRPELFQKPSESDFYDALVKLVPQTQAAQESRNYQLLVA
HHHEEEECCCCCCCCCCCHHCCCHHHHCCCCCCHHHHHHHHHHCCHHHHHHCCCCEEEHH
GLVEIAPTVSNFFDGADSVLVIDPDPEIKRNRLNILGLLRNHARVLADFGAIVKNL
HHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PGFLLEVGTEELPASFLGGAIAQWRSRIPQSLAANSLTSESVEVYGTPRRLAVLITGLP
CCCEEECCCHHCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCEEEECCCCEEEEEEECCC
SQQPDREEEIKGPPAQAAFKDGQPTPAAVGFAKKQGVELEALEVRPTDKGEFVFIQKKTP
CCCCCCHHHCCCCCCCCCCCCCCCCCHHHCHHHHCCCCEEEEEECCCCCCCEEEEECCCC
GRPVADILTELVPQWIYSLEGKRLMRWGDGDVRFSRPIRWLVALLDEAILPLELVNGSLT
CCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHEECCEEE
VKSDRISYGHRVLHPAPITIQKAGDYVNTLRDGYVTVNAKERTTTIKEQVAATVQKLGGY
EECCCCCCCCEEECCCCEEEECCCCHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHCCH
TEIYPDLLEEVTNLVEWPSPVVGKFEEEFLNLPTEVTTTVMVSHQRYFPVFKTGDHKELL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHEEEECCCCCCCEECCCCCCCC
PYFITVSNGDPTKSEVIAVGNERVIRARLADGQFFYKTDLSKSLESYLPQLETVTFQEDL
EEEEEECCCCCCCCCEEEECCCEEEEEEECCCCEEEHHHHHHHHHHHCCHHHEEHHHHHH
GSLRGKVERIVKVAAQISSQLQLGEGDRQNNQRAALLCKADLVTQMVFEFPELQGIMGQK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHCHHHHHHCCCC
YAVASGESPEVSTAIVEHYLPRGADDILPQTLTGQVVGLADRLDTLVSIFGLGLIPTGSS
EEECCCCCCCHHHHHHHHHCCCCCHHHCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCCCC
DPFALRRAANAVVNITWAANLQINLASLLAQTVAEFAAQYNKDQAPLITALNEFFLQRIR
CCHHHHHHCCEEEEEEEEECCEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
TLLQEEKQIDYDLVNAVLGENDPEYTERALQDLLDVRDRALYLQQIRRDGTLDKIYETVN
HHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
RSTRLAAQGDLDTQQLDPTSVVRPELFQKPSESDFYDALVKLVPQTQAAQESRNYQLLVA
HHHEEEECCCCCCCCCCCHHCCCHHHHCCCCCCHHHHHHHHHHCCHHHHHHCCCCEEEHH
GLVEIAPTVSNFFDGADSVLVIDPDPEIKRNRLNILGLLRNHARVLADFGAIVKNL
HHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840