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The map label for this gene is hrcA [H]

Identifier: 17231536

GI number: 17231536

Start: 4871168

End: 4872265

Strand: Direct

Name: hrcA [H]

Synonym: alr4044

Alternate gene names: 17231536

Gene position: 4871168-4872265 (Clockwise)

Preceding gene: 17231535

Following gene: 17231537

Centisome position: 75.95

GC content: 46.36

Gene sequence:

>1098_bases
ATGCAAGTCCAGTTGACTAATCGACAACAGCATATACTTTGGGCAACGGTACGTCATTATATAGCTACAGCAGAGCCTGT
TGGCTCAAAAGCTTTGGTCGAGGAATACGACTTGGGCGTTAGCTCTGCCACAATTCGCAATGTAATGGGCGTACTAGAGA
AATCTGGGTTATTGTACCAACCGCATACATCTGCTGGACGAGTACCTTCTGACTCAGGTTATCGCATTTATGTTGACCAG
TTAATTACCCCCTCTCTGCGAGACACTACACGAGCAGAAGTTTTAGCAAAAGAGGTAGAATCAGCCCTACAACAGCATCT
GCAATGGGAAGACTGGAGTCTGGAAATACTGTTGCAAGGAGCCGCCCAGATTTTAGCTAGCTTGAGTGGGTGTATTAGCT
TGATTACTATGCCCCAAACCAACACAGCATCCGTAAGACATTTGCAGTTAATGCAGATAGAAACGGGACGAATCATGCTG
ATATTGGTGACGGATAGTTATGAAACCCACTCAAAGCTGATGGATTTACCCCCAGCGAGGAGCGAAACAAAACCCGACCC
AGAAGTAATTGACAGGGAATTACAAATTGTTTCTAACTTCTTAAATAGTCACTTACGGGGGCGGAGTCTGTTAGAAATCA
GTACTCTGGATTGGAGTCAATTAGATCGAGAATTTCAAAGTTATGGAGAGTTTCTAAAAAATTCCGTAGCAGAATTAGCC
CACCGCAGTGCTGCGCCGGCTGCAACTCAAATCATGGTGCGGGGTTTGGCAGAAGTGTTGCGTCAACCGGAATTCTCCCA
GCTTCAGCAAGTGAAAACGATTATACAACTATTGGAAGAAGAACAAGAGCAACTGTGGCGGCTAATATTTGAGGAACCAG
AGTTAGAAGATACGCACAAATCCAAGGTAACAGTGCGTATCGGCGCAGAAAACCCGTTAGAACCGATACGCACCTGCTCC
TTAATTTCTTCTACCTATCGCCGGGGAGGAGTCCCGTTGGGTAGTGTGGGAGTTTTGGGGCCGACACGCCTAGATTACGA
AAGTGCGATCGCAGTTGTAGCGGCTGCTGCTGATTACCTCTCAGAAGCCTTCAGTTAA

Upstream 100 bases:

>100_bases
TATATTTTGCGTTTCTAATTAACTATTATGAATTTTTGCTTTAAAATTTCACAATTTTTCAAAATCTACTTAGCATTTGC
CTTCCGTCAAACATATCCCT

Downstream 100 bases:

>100_bases
ATTAGATGAAATCATGGTCAGAAAAATTGCCTTTGGGGTGCTGTGGTTAGGGTTTACGTTTTATGCTTTTGTCCTTGCTC
CTCCCGATCAACCCGATACA

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MQVQLTNRQQHILWATVRHYIATAEPVGSKALVEEYDLGVSSATIRNVMGVLEKSGLLYQPHTSAGRVPSDSGYRIYVDQ
LITPSLRDTTRAEVLAKEVESALQQHLQWEDWSLEILLQGAAQILASLSGCISLITMPQTNTASVRHLQLMQIETGRIML
ILVTDSYETHSKLMDLPPARSETKPDPEVIDRELQIVSNFLNSHLRGRSLLEISTLDWSQLDREFQSYGEFLKNSVAELA
HRSAAPAATQIMVRGLAEVLRQPEFSQLQQVKTIIQLLEEEQEQLWRLIFEEPELEDTHKSKVTVRIGAENPLEPIRTCS
LISSTYRRGGVPLGSVGVLGPTRLDYESAIAVVAAAADYLSEAFS

Sequences:

>Translated_365_residues
MQVQLTNRQQHILWATVRHYIATAEPVGSKALVEEYDLGVSSATIRNVMGVLEKSGLLYQPHTSAGRVPSDSGYRIYVDQ
LITPSLRDTTRAEVLAKEVESALQQHLQWEDWSLEILLQGAAQILASLSGCISLITMPQTNTASVRHLQLMQIETGRIML
ILVTDSYETHSKLMDLPPARSETKPDPEVIDRELQIVSNFLNSHLRGRSLLEISTLDWSQLDREFQSYGEFLKNSVAELA
HRSAAPAATQIMVRGLAEVLRQPEFSQLQQVKTIIQLLEEEQEQLWRLIFEEPELEDTHKSKVTVRIGAENPLEPIRTCS
LISSTYRRGGVPLGSVGVLGPTRLDYESAIAVVAAAADYLSEAFS
>Mature_365_residues
MQVQLTNRQQHILWATVRHYIATAEPVGSKALVEEYDLGVSSATIRNVMGVLEKSGLLYQPHTSAGRVPSDSGYRIYVDQ
LITPSLRDTTRAEVLAKEVESALQQHLQWEDWSLEILLQGAAQILASLSGCISLITMPQTNTASVRHLQLMQIETGRIML
ILVTDSYETHSKLMDLPPARSETKPDPEVIDRELQIVSNFLNSHLRGRSLLEISTLDWSQLDREFQSYGEFLKNSVAELA
HRSAAPAATQIMVRGLAEVLRQPEFSQLQQVKTIIQLLEEEQEQLWRLIFEEPELEDTHKSKVTVRIGAENPLEPIRTCS
LISSTYRRGGVPLGSVGVLGPTRLDYESAIAVVAAAADYLSEAFS

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 40741; Mature: 40741

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVQLTNRQQHILWATVRHYIATAEPVGSKALVEEYDLGVSSATIRNVMGVLEKSGLLYQ
CEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEC
PHTSAGRVPSDSGYRIYVDQLITPSLRDTTRAEVLAKEVESALQQHLQWEDWSLEILLQG
CCCCCCCCCCCCCCEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
AAQILASLSGCISLITMPQTNTASVRHLQLMQIETGRIMLILVTDSYETHSKLMDLPPAR
HHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEEECCCCEEEEEEECCCHHHHHHHCCCCCC
SETKPDPEVIDRELQIVSNFLNSHLRGRSLLEISTLDWSQLDREFQSYGEFLKNSVAELA
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
HRSAAPAATQIMVRGLAEVLRQPEFSQLQQVKTIIQLLEEEQEQLWRLIFEEPELEDTHK
HHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SKVTVRIGAENPLEPIRTCSLISSTYRRGGVPLGSVGVLGPTRLDYESAIAVVAAAADYL
CEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
SEAFS
HHHCC
>Mature Secondary Structure
MQVQLTNRQQHILWATVRHYIATAEPVGSKALVEEYDLGVSSATIRNVMGVLEKSGLLYQ
CEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEC
PHTSAGRVPSDSGYRIYVDQLITPSLRDTTRAEVLAKEVESALQQHLQWEDWSLEILLQG
CCCCCCCCCCCCCCEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
AAQILASLSGCISLITMPQTNTASVRHLQLMQIETGRIMLILVTDSYETHSKLMDLPPAR
HHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEEECCCCEEEEEEECCCHHHHHHHCCCCCC
SETKPDPEVIDRELQIVSNFLNSHLRGRSLLEISTLDWSQLDREFQSYGEFLKNSVAELA
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
HRSAAPAATQIMVRGLAEVLRQPEFSQLQQVKTIIQLLEEEQEQLWRLIFEEPELEDTHK
HHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SKVTVRIGAENPLEPIRTCSLISSTYRRGGVPLGSVGVLGPTRLDYESAIAVVAAAADYL
CEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
SEAFS
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA