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The map label for this gene is trxA [H]

Identifier: 17231447

GI number: 17231447

Start: 4773752

End: 4774138

Strand: Direct

Name: trxA [H]

Synonym: alr3955

Alternate gene names: 17231447

Gene position: 4773752-4774138 (Clockwise)

Preceding gene: 17231446

Following gene: 17231448

Centisome position: 74.43

GC content: 41.34

Gene sequence:

>387_bases
ATGGTGTTGTCGGTTAGTGAGCGGACATTTACTCAAGAAGTTTTAGAATCTCCGGTTCCGGTTTTAGTAAATTTTGAAGC
ACCCTGGTGTGGATTGTGTCGCATTATCCACCCTTTGTTATTACAATTTCAATCTCAATGCGGCGAACAAATTAAACTAG
TTGGGGTGAACGCTGACGAGAATTTCAAACTTTCTAACACTTATCGTTTAAAGTCTTTGCCCACGTTACTTTTGATTGAA
AATGGAATCGTTCGCCATCGTCTAGAAGGGTTTCGCGGCAGAGATGACCTACGGTTAGCTTTAGAAGAAATCAAACTCAA
TTATACCAACCGTCCTAAAGCATACACTAGCTCTAAAACGGCAGACTTAGAATGTCGGACAGCGTGA

Upstream 100 bases:

>100_bases
GCGGTACTGAAATATAGCTGCTATAAAACATTAACTAGCTTGCTAACTTCTTCTGCTGATAGCTAGTTTGATAGTAAAAC
CCTATAATTCTAGAGGCGTC

Downstream 100 bases:

>100_bases
TTGGGAATTGGGTATTAAGTTTCGGGTGTTGGGTCAAATCCTTCCCAATTCCCAGTCTCCAGTCCCCAAATCTAAAACCA
TGCTTAATACCCCACTCAAT

Product: thioredoxin

Products: NA

Alternate protein names: Trx-1; Thioredoxin-M [H]

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MVLSVSERTFTQEVLESPVPVLVNFEAPWCGLCRIIHPLLLQFQSQCGEQIKLVGVNADENFKLSNTYRLKSLPTLLLIE
NGIVRHRLEGFRGRDDLRLALEEIKLNYTNRPKAYTSSKTADLECRTA

Sequences:

>Translated_128_residues
MVLSVSERTFTQEVLESPVPVLVNFEAPWCGLCRIIHPLLLQFQSQCGEQIKLVGVNADENFKLSNTYRLKSLPTLLLIE
NGIVRHRLEGFRGRDDLRLALEEIKLNYTNRPKAYTSSKTADLECRTA
>Mature_128_residues
MVLSVSERTFTQEVLESPVPVLVNFEAPWCGLCRIIHPLLLQFQSQCGEQIKLVGVNADENFKLSNTYRLKSLPTLLLIE
NGIVRHRLEGFRGRDDLRLALEEIKLNYTNRPKAYTSSKTADLECRTA

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI87082331, Length=97, Percent_Identity=28.8659793814433, Blast_Score=63, Evalue=6e-12,
Organism=Escherichia coli, GI1788936, Length=79, Percent_Identity=31.6455696202532, Blast_Score=61, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28573567, Length=98, Percent_Identity=33.6734693877551, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24639068, Length=82, Percent_Identity=35.3658536585366, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 14590; Mature: 14590

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLSVSERTFTQEVLESPVPVLVNFEAPWCGLCRIIHPLLLQFQSQCGEQIKLVGVNADE
CEEECCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCC
NFKLSNTYRLKSLPTLLLIENGIVRHRLEGFRGRDDLRLALEEIKLNYTNRPKAYTSSKT
CEEECCEEECCCCCEEEEECCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
ADLECRTA
CCEEEECC
>Mature Secondary Structure
MVLSVSERTFTQEVLESPVPVLVNFEAPWCGLCRIIHPLLLQFQSQCGEQIKLVGVNADE
CEEECCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCC
NFKLSNTYRLKSLPTLLLIENGIVRHRLEGFRGRDDLRLALEEIKLNYTNRPKAYTSSKT
CEEECCEEECCCCCEEEEECCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
ADLECRTA
CCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2492995 [H]