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The map label for this gene is cobB [H]

Identifier: 17231426

GI number: 17231426

Start: 4750862

End: 4752406

Strand: Direct

Name: cobB [H]

Synonym: alr3934

Alternate gene names: 17231426

Gene position: 4750862-4752406 (Clockwise)

Preceding gene: 17231424

Following gene: 17231427

Centisome position: 74.07

GC content: 49.9

Gene sequence:

>1545_bases
ATGGCTTTAGTTATTGCTGGGGAACGTAGTGGGGTGGGCAAGACAACAGTCACGCTCACCCTTTTAGCATCTTTATGTCG
GCGTAGTGCCATAGTGCAATCCTTCAAAGTCGGGCCAGACTATATTGACCCGATGTTTCACACCTATGTTACTGGTCGTG
CTTGCCGCAATTTAGATCCAGTTTTAACTTCAGAAGCTTACGTTCAGCAATGTTTTGCTCGTCATTACCAAGAGAGTGAA
TATGCTCTGGTTGAAGGAGTGATGGGGTTGTTTGATGGAATTGGGAGGCAGGAAGCAGGGGGGCAGGGGGCAGGGGGCAG
GGAGAATAACTTTAGTACTTCCCATTCAGCACTCACTACTGACTTTGCTAGTACGGCTCATGTGGCGCGGCTTTTAGATT
TGCCGGTGGTTTTGGTGATTGATTGTAGTCGCTTGTCTGGTTCTGTGGCAGCGATCGCCCACGGTTACTGCTCTTTTGAT
CCGCGCATTAAAATGGCTGGGGTGGTGTTAAATCGCGTGGGCAGCGATCGCCATCTCTCTCTCCTCCAAGATGCCCTGAA
ACCTCTGCAATTACCTATACTCGGTGTACTACGTCGTCAAGATGACATTACCATTCCCGATCGCCATCTCGGTTTGATCC
CCACTGCCGAACTACCAGAGTTAAATGCCGTCATCAATCGTCTTGCTGATTTAGGTGATACTTGTTTCGATTGGCAAAAT
TTATTACCTCTGTTGCAGGCGAAAGAGGTAGGGGGCAGGGAGCAGGGAGCAGGGAGCAGGGGGCAGGGAGCAGGGGAGGC
AGGGGAGGCAGGGGGAGAACTGACTGCAAGATTTTCGCCCAATCCCCAATCCCCAATCCCCAATCCCCAATCCCCAGTCC
CCCATCCCCCTAAAATCGCCGTTGCCCGCGATCGCGCTTTTAACTTCTATTACCAAGACAATCTTGATTTGTTGCAGCAG
TTGGGGGCGGAACTGGTTTTCTGGAGTCCTTTAACAGATGGGGAACTACCATCTGGTGTACGGGGAATGTACTTTGGTGG
CGGTTTTCCAGAAGTGTTTGCCTCACAGCTAGCCGAAAATAGTAGCGCCCGTGATGCGGTGAAACAAGCTATTCTCGCAG
GAATGCCCACGATTGCTGAATGTGGGGGGTTGATGTATTTGTGTGAGCAAATTATCGATTTTGAGGGGCAATCCTGGCCG
ATGGTGGGAGTTTTACCAACATCTGCGGCAATGGGTGGACGTTTAACTTTGGGATATCGCCGTGCTGTAGCCTTGCAAGA
TAGCTTGTTAGTGAATGTAGGCACCCACATTTACGGACACGAGTTTCATCGCTCACGGCTGATTACAGCGCCCACTCAGC
CCTTATTTGAAACTTACCGCTATGATTGTCCAGAAAATATGGGTTGTGAAGGATGGGGTTTCCCGAAAAATATCCATGCC
TCTTACGTTCACCTTCACTGGGGAGAGAGTGGAGAAATTCCCCGGCAGTTTATTCAGCAGTGCGCTTATTTTGGCGAAAC
CATTGATTTAGTGCATATGTACTAA

Upstream 100 bases:

>100_bases
CAGAACTTTTCAAGAGAGAGGGGTTGGGGGAGAGGTCAAAAAAGGCTTGTCGAACTCACGTTCTTCTAAGATTTAAGCGA
ATCAAGACTTCTATCCTGTT

Downstream 100 bases:

>100_bases
ATATTAGGTGATGACAAGGCTTGGCGATCGCCAAATGACCCTGGTTAAACATGACAGAGATTAATTTTGTTAACACAATT
TAACATTCAGTAGTTGAGTA

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 513

Protein sequence:

>514_residues
MALVIAGERSGVGKTTVTLTLLASLCRRSAIVQSFKVGPDYIDPMFHTYVTGRACRNLDPVLTSEAYVQQCFARHYQESE
YALVEGVMGLFDGIGRQEAGGQGAGGRENNFSTSHSALTTDFASTAHVARLLDLPVVLVIDCSRLSGSVAAIAHGYCSFD
PRIKMAGVVLNRVGSDRHLSLLQDALKPLQLPILGVLRRQDDITIPDRHLGLIPTAELPELNAVINRLADLGDTCFDWQN
LLPLLQAKEVGGREQGAGSRGQGAGEAGEAGGELTARFSPNPQSPIPNPQSPVPHPPKIAVARDRAFNFYYQDNLDLLQQ
LGAELVFWSPLTDGELPSGVRGMYFGGGFPEVFASQLAENSSARDAVKQAILAGMPTIAECGGLMYLCEQIIDFEGQSWP
MVGVLPTSAAMGGRLTLGYRRAVALQDSLLVNVGTHIYGHEFHRSRLITAPTQPLFETYRYDCPENMGCEGWGFPKNIHA
SYVHLHWGESGEIPRQFIQQCAYFGETIDLVHMY

Sequences:

>Translated_514_residues
MALVIAGERSGVGKTTVTLTLLASLCRRSAIVQSFKVGPDYIDPMFHTYVTGRACRNLDPVLTSEAYVQQCFARHYQESE
YALVEGVMGLFDGIGRQEAGGQGAGGRENNFSTSHSALTTDFASTAHVARLLDLPVVLVIDCSRLSGSVAAIAHGYCSFD
PRIKMAGVVLNRVGSDRHLSLLQDALKPLQLPILGVLRRQDDITIPDRHLGLIPTAELPELNAVINRLADLGDTCFDWQN
LLPLLQAKEVGGREQGAGSRGQGAGEAGEAGGELTARFSPNPQSPIPNPQSPVPHPPKIAVARDRAFNFYYQDNLDLLQQ
LGAELVFWSPLTDGELPSGVRGMYFGGGFPEVFASQLAENSSARDAVKQAILAGMPTIAECGGLMYLCEQIIDFEGQSWP
MVGVLPTSAAMGGRLTLGYRRAVALQDSLLVNVGTHIYGHEFHRSRLITAPTQPLFETYRYDCPENMGCEGWGFPKNIHA
SYVHLHWGESGEIPRQFIQQCAYFGETIDLVHMY
>Mature_513_residues
ALVIAGERSGVGKTTVTLTLLASLCRRSAIVQSFKVGPDYIDPMFHTYVTGRACRNLDPVLTSEAYVQQCFARHYQESEY
ALVEGVMGLFDGIGRQEAGGQGAGGRENNFSTSHSALTTDFASTAHVARLLDLPVVLVIDCSRLSGSVAAIAHGYCSFDP
RIKMAGVVLNRVGSDRHLSLLQDALKPLQLPILGVLRRQDDITIPDRHLGLIPTAELPELNAVINRLADLGDTCFDWQNL
LPLLQAKEVGGREQGAGSRGQGAGEAGEAGGELTARFSPNPQSPIPNPQSPVPHPPKIAVARDRAFNFYYQDNLDLLQQL
GAELVFWSPLTDGELPSGVRGMYFGGGFPEVFASQLAENSSARDAVKQAILAGMPTIAECGGLMYLCEQIIDFEGQSWPM
VGVLPTSAAMGGRLTLGYRRAVALQDSLLVNVGTHIYGHEFHRSRLITAPTQPLFETYRYDCPENMGCEGWGFPKNIHAS
YVHLHWGESGEIPRQFIQQCAYFGETIDLVHMY

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 55890; Mature: 55759

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVIAGERSGVGKTTVTLTLLASLCRRSAIVQSFKVGPDYIDPMFHTYVTGRACRNLDP
CEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
VLTSEAYVQQCFARHYQESEYALVEGVMGLFDGIGRQEAGGQGAGGRENNFSTSHSALTT
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHH
DFASTAHVARLLDLPVVLVIDCSRLSGSVAAIAHGYCSFDPRIKMAGVVLNRVGSDRHLS
HHHHHHHHHHHHCCCEEEEEECCHHCCCHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHH
LLQDALKPLQLPILGVLRRQDDITIPDRHLGLIPTAELPELNAVINRLADLGDTCFDWQN
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHH
LLPLLQAKEVGGREQGAGSRGQGAGEAGEAGGELTARFSPNPQSPIPNPQSPVPHPPKIA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEE
VARDRAFNFYYQDNLDLLQQLGAELVFWSPLTDGELPSGVRGMYFGGGFPEVFASQLAEN
EECCCEEEEEECCCHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCC
SSARDAVKQAILAGMPTIAECGGLMYLCEQIIDFEGQSWPMVGVLPTSAAMGGRLTLGYR
CCHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEECHH
RAVALQDSLLVNVGTHIYGHEFHRSRLITAPTQPLFETYRYDCPENMGCEGWGFPKNIHA
HHHHHHHHHHEECCCHHHCCHHHHCCEECCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCE
SYVHLHWGESGEIPRQFIQQCAYFGETIDLVHMY
EEEEEEECCCCCHHHHHHHHHHHCCCCEEEEECC
>Mature Secondary Structure 
ALVIAGERSGVGKTTVTLTLLASLCRRSAIVQSFKVGPDYIDPMFHTYVTGRACRNLDP
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
VLTSEAYVQQCFARHYQESEYALVEGVMGLFDGIGRQEAGGQGAGGRENNFSTSHSALTT
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHH
DFASTAHVARLLDLPVVLVIDCSRLSGSVAAIAHGYCSFDPRIKMAGVVLNRVGSDRHLS
HHHHHHHHHHHHCCCEEEEEECCHHCCCHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHH
LLQDALKPLQLPILGVLRRQDDITIPDRHLGLIPTAELPELNAVINRLADLGDTCFDWQN
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHH
LLPLLQAKEVGGREQGAGSRGQGAGEAGEAGGELTARFSPNPQSPIPNPQSPVPHPPKIA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEE
VARDRAFNFYYQDNLDLLQQLGAELVFWSPLTDGELPSGVRGMYFGGGFPEVFASQLAEN
EECCCEEEEEECCCHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCC
SSARDAVKQAILAGMPTIAECGGLMYLCEQIIDFEGQSWPMVGVLPTSAAMGGRLTLGYR
CCHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEECHH
RAVALQDSLLVNVGTHIYGHEFHRSRLITAPTQPLFETYRYDCPENMGCEGWGFPKNIHA
HHHHHHHHHHEECCCHHHCCHHHHCCEECCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCE
SYVHLHWGESGEIPRQFIQQCAYFGETIDLVHMY
EEEEEEECCCCCHHHHHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA