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The map label for this gene is blh [H]

Identifier: 17231396

GI number: 17231396

Start: 4707858

End: 4708559

Strand: Direct

Name: blh [H]

Synonym: alr3904

Alternate gene names: 17231396

Gene position: 4707858-4708559 (Clockwise)

Preceding gene: 17231393

Following gene: 17231397

Centisome position: 73.4

GC content: 45.44

Gene sequence:

>702_bases
ATGTTATTTCGGCAACTTTTTGACCCAGAGACCAGCACTTACACTTATTTGATTGCAGACTTGGAAACTAAAACTGCGGC
ATTGGTTGACCCAGTGCTGGAACAAGTAGAACGTGACCAGAAGTTATTGACAGAACTGGATTTGACACTAGGCTACTGTT
TGGAGACACATATCCACGCTGACCACATCACAGGTGCGGGGAAACTGCGAGAGAAAATAGGATGTGAAAACATTGTGCCT
TTTGGCGCAAATGCTGCCTGTGCTAACAAAAAAATGCAGCCTGGTGACGTGCTGCAATTTGGGTCAGTTGTCATTGAAGC
TATTGCTACACCAGGACACACGGATAGTCACTTGGCTTATTTGGTCAATAAAACCCACTTACTCACAGGAGATTCCCTGC
TGATTCGTGGCTGTGGACGCACGGATTTTCAAAGTGGTAGTGCAGCAGTACTTTACGACAGTATTACCAAAAATCTCTGG
ACACTACCTGAGACGACACTCGTTTATCCAGGTCACGATTATCACGGACAAACAGTGTCCACAATTGGCGAAGAGAAAAA
GTTTAATCTGCGATTGGTTGGGCGCAGTCGTTCAGAATTTATCGAGTTGATGGGCAATTTAAATCTGCCAAATCCGCAGA
AAATTATGGAAGCTGTGCCAGCAAACCAGCGCTGCGGCAATGTGGCGATGACTACTCTTTGA

Upstream 100 bases:

>100_bases
ATATTTTTGATTGACAATTTATATTAAAGCATTATAAAACATAAATATTATATTACTATATAGTAGTATAGTAGACACAA
GCCCCTATTTATCAAAAACT

Downstream 100 bases:

>100_bases
GTTTCAGGGTTTAGAGATTAGTATTTTTGACAAGGAATTAAAACAATGACAAACACTAAAAATTTGACGGAAATCGATGC
AATCACACTTAAGCAATGGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MLFRQLFDPETSTYTYLIADLETKTAALVDPVLEQVERDQKLLTELDLTLGYCLETHIHADHITGAGKLREKIGCENIVP
FGANAACANKKMQPGDVLQFGSVVIEAIATPGHTDSHLAYLVNKTHLLTGDSLLIRGCGRTDFQSGSAAVLYDSITKNLW
TLPETTLVYPGHDYHGQTVSTIGEEKKFNLRLVGRSRSEFIELMGNLNLPNPQKIMEAVPANQRCGNVAMTTL

Sequences:

>Translated_233_residues
MLFRQLFDPETSTYTYLIADLETKTAALVDPVLEQVERDQKLLTELDLTLGYCLETHIHADHITGAGKLREKIGCENIVP
FGANAACANKKMQPGDVLQFGSVVIEAIATPGHTDSHLAYLVNKTHLLTGDSLLIRGCGRTDFQSGSAAVLYDSITKNLW
TLPETTLVYPGHDYHGQTVSTIGEEKKFNLRLVGRSRSEFIELMGNLNLPNPQKIMEAVPANQRCGNVAMTTL
>Mature_233_residues
MLFRQLFDPETSTYTYLIADLETKTAALVDPVLEQVERDQKLLTELDLTLGYCLETHIHADHITGAGKLREKIGCENIVP
FGANAACANKKMQPGDVLQFGSVVIEAIATPGHTDSHLAYLVNKTHLLTGDSLLIRGCGRTDFQSGSAAVLYDSITKNLW
TLPETTLVYPGHDYHGQTVSTIGEEKKFNLRLVGRSRSEFIELMGNLNLPNPQKIMEAVPANQRCGNVAMTTL

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=228, Percent_Identity=50, Blast_Score=230, Evalue=8e-61,
Organism=Homo sapiens, GI94538322, Length=170, Percent_Identity=35.2941176470588, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI94538320, Length=170, Percent_Identity=35.2941176470588, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI21703352, Length=193, Percent_Identity=32.6424870466321, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI116642887, Length=193, Percent_Identity=32.6424870466321, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI46361987, Length=170, Percent_Identity=30.5882352941176, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI14150041, Length=170, Percent_Identity=30.5882352941176, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1787158, Length=194, Percent_Identity=30.9278350515464, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538952, Length=226, Percent_Identity=42.9203539823009, Blast_Score=189, Evalue=8e-49,
Organism=Caenorhabditis elegans, GI17536925, Length=185, Percent_Identity=27.5675675675676, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6320478, Length=193, Percent_Identity=27.979274611399, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324614, Length=201, Percent_Identity=25.8706467661692, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI221330176, Length=227, Percent_Identity=48.8986784140969, Blast_Score=239, Evalue=8e-64,
Organism=Drosophila melanogaster, GI24667703, Length=175, Percent_Identity=35.4285714285714, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21356335, Length=175, Percent_Identity=35.4285714285714, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24667711, Length=175, Percent_Identity=35.4285714285714, Blast_Score=93, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 25630; Mature: 25630

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFRQLFDPETSTYTYLIADLETKTAALVDPVLEQVERDQKLLTELDLTLGYCLETHIHA
CCCHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DHITGAGKLREKIGCENIVPFGANAACANKKMQPGDVLQFGSVVIEAIATPGHTDSHLAY
HHCCCHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEE
LVNKTHLLTGDSLLIRGCGRTDFQSGSAAVLYDSITKNLWTLPETTLVYPGHDYHGQTVS
EECCEEEEECCCEEEEECCCCCCCCCCEEEEEHHHHHHHCCCCCCEEEECCCCCCCCHHH
TIGEEKKFNLRLVGRSRSEFIELMGNLNLPNPQKIMEAVPANQRCGNVAMTTL
HCCCCCCEEEEEECCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCEEEECC
>Mature Secondary Structure
MLFRQLFDPETSTYTYLIADLETKTAALVDPVLEQVERDQKLLTELDLTLGYCLETHIHA
CCCHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DHITGAGKLREKIGCENIVPFGANAACANKKMQPGDVLQFGSVVIEAIATPGHTDSHLAY
HHCCCHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEE
LVNKTHLLTGDSLLIRGCGRTDFQSGSAAVLYDSITKNLWTLPETTLVYPGHDYHGQTVS
EECCEEEEECCCEEEEECCCCCCCCCCEEEEEHHHHHHHCCCCCCEEEECCCCCCCCHHH
TIGEEKKFNLRLVGRSRSEFIELMGNLNLPNPQKIMEAVPANQRCGNVAMTTL
HCCCCCCEEEEEECCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]