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The map label for this gene is csd [H]

Identifier: 17231359

GI number: 17231359

Start: 4667104

End: 4668498

Strand: Direct

Name: csd [H]

Synonym: alr3867

Alternate gene names: 17231359

Gene position: 4667104-4668498 (Clockwise)

Preceding gene: 17231356

Following gene: 17231363

Centisome position: 72.77

GC content: 44.8

Gene sequence:

>1395_bases
ATGTCAACACCATCAACTAAGGAGTCTGACATGGAAGCTTTAGACTTGAAATGGATACGTGGGCAGTTTCCGGCACTTAC
ACAAAAAATTAACGGACAACCAGCTATATTTTTTGATGGCCCTGGTGGAACACAAGTACCTGGGTCTGTTTTAGATGCTA
TCAGTGACTATTTAGTTAGGTCAAATGCTAATGCTCACGGGGCTTTTGCTACGAGTGCGCGGACGGATGCTTTAATTATT
GCAGCTAGGACGGCGATCGCTGATTTTTTGGGTTGCCACAGTGATGAGGTGGTTTTCGGCGCTAATATGACGACGCTCAC
CTTTACTTTAAGTCGCGCTATTGGACGAACGCTGCAACCGGGTGATGAAATTATTGTGACACGCCTTGACCATTCGGCTA
ATGTTTCTTCTTGGGAAGCGTTGGCAGAACAAGGTGCAGTGATTCGTTATGTCGATGTCAAAGTTGATGATTGCACTTTA
GATATCAATGATTTGGAGCAACAAATCAATTCCCGTACCAAGTTAGTAGCCGTCTCTTATGCTTCCAACGCTGTGGGGAC
GATTAACGATATTGCCACTATCGTCAAACTAGCCCATTCTGTAGGTGCATTGGTGTTTGTCGATGCAGTCCATTATGCTC
CTCATGGGCCGATAAACGTTCATGCTTTGGGGTGTGATTTTCTCGCCTGTTCTGCATACAAATTCTTTGCCCCCCATGTT
GGGATTTTGTATGGTAAGCGGGAACATCTTGCAAATCTGCAACCTTATAAAGTCAAACCAGCACCCAATGAAGTCCCATC
TCGTTGGGAAACTGGAACCCTAAATTATGAAGGATTGGCGGGTGTAGTCGCGGCGGTTAACTATTTGGCAAAATTAGGTT
GTCATGTCTCCCCGACAGTTGACCAAGAGTTAGTTTCAGCATTGATTGAGGCTGATAAGGAAGGTTTGGAACACTTCCAC
TGTCCCCGATTTTTAACATCAGCAGAACAACCATCACATGAAATTGCCTCGGCTTATCACAGTCGTCGGGCGGCAATAGT
TGCAGCCATGTCAGCGATTCAGCAATACGAAAGAGAATTGAGCTATAAGCTAATTTCCGGCTTGCTAGAAATTCCTGGCT
TAACTTTATATGGCATTACAGATCCAGAACGCTTTGCTTGGCGGACACCAACAGTAGCAATTCGACTCCAGGGTAAAAGC
CCAGAAAGCATTGCGAGGACATTAGGCGATCGCGGTATTTTCTCCTGGCATGGTAACTTTTATGCCTTGAATCTGACTGA
GAAACTAGGTGTAGAAAGCAATGGCGGCTTATTGCGCCTGGGTTTAGTACACTACAATTCTGTGGAAGAGATTATACAAT
TACTCCAAGCTTTAAAAGAAATTGGGCTTGACTAA

Upstream 100 bases:

>100_bases
AGACATAAATTAATGAATCCTTTTTGTAAGTTGTCAGTTGTCATTTGTTACTTCCCCTACACCCTTACACCCTTACACCC
CTACAACTAAGCTAAGGTGT

Downstream 100 bases:

>100_bases
ATCAAGACAATAGAAATATTGGTAAGGATCAGGTGGTGGGGTATTGACACTAAATCCACGGGGCATTGTCTATCAAAGCA
TTTAACATCTGCTGGAATTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MSTPSTKESDMEALDLKWIRGQFPALTQKINGQPAIFFDGPGGTQVPGSVLDAISDYLVRSNANAHGAFATSARTDALII
AARTAIADFLGCHSDEVVFGANMTTLTFTLSRAIGRTLQPGDEIIVTRLDHSANVSSWEALAEQGAVIRYVDVKVDDCTL
DINDLEQQINSRTKLVAVSYASNAVGTINDIATIVKLAHSVGALVFVDAVHYAPHGPINVHALGCDFLACSAYKFFAPHV
GILYGKREHLANLQPYKVKPAPNEVPSRWETGTLNYEGLAGVVAAVNYLAKLGCHVSPTVDQELVSALIEADKEGLEHFH
CPRFLTSAEQPSHEIASAYHSRRAAIVAAMSAIQQYERELSYKLISGLLEIPGLTLYGITDPERFAWRTPTVAIRLQGKS
PESIARTLGDRGIFSWHGNFYALNLTEKLGVESNGGLLRLGLVHYNSVEEIIQLLQALKEIGLD

Sequences:

>Translated_464_residues
MSTPSTKESDMEALDLKWIRGQFPALTQKINGQPAIFFDGPGGTQVPGSVLDAISDYLVRSNANAHGAFATSARTDALII
AARTAIADFLGCHSDEVVFGANMTTLTFTLSRAIGRTLQPGDEIIVTRLDHSANVSSWEALAEQGAVIRYVDVKVDDCTL
DINDLEQQINSRTKLVAVSYASNAVGTINDIATIVKLAHSVGALVFVDAVHYAPHGPINVHALGCDFLACSAYKFFAPHV
GILYGKREHLANLQPYKVKPAPNEVPSRWETGTLNYEGLAGVVAAVNYLAKLGCHVSPTVDQELVSALIEADKEGLEHFH
CPRFLTSAEQPSHEIASAYHSRRAAIVAAMSAIQQYERELSYKLISGLLEIPGLTLYGITDPERFAWRTPTVAIRLQGKS
PESIARTLGDRGIFSWHGNFYALNLTEKLGVESNGGLLRLGLVHYNSVEEIIQLLQALKEIGLD
>Mature_463_residues
STPSTKESDMEALDLKWIRGQFPALTQKINGQPAIFFDGPGGTQVPGSVLDAISDYLVRSNANAHGAFATSARTDALIIA
ARTAIADFLGCHSDEVVFGANMTTLTFTLSRAIGRTLQPGDEIIVTRLDHSANVSSWEALAEQGAVIRYVDVKVDDCTLD
INDLEQQINSRTKLVAVSYASNAVGTINDIATIVKLAHSVGALVFVDAVHYAPHGPINVHALGCDFLACSAYKFFAPHVG
ILYGKREHLANLQPYKVKPAPNEVPSRWETGTLNYEGLAGVVAAVNYLAKLGCHVSPTVDQELVSALIEADKEGLEHFHC
PRFLTSAEQPSHEIASAYHSRRAAIVAAMSAIQQYERELSYKLISGLLEIPGLTLYGITDPERFAWRTPTVAIRLQGKSP
ESIARTLGDRGIFSWHGNFYALNLTEKLGVESNGGLLRLGLVHYNSVEEIIQLLQALKEIGLD

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=215, Percent_Identity=25.1162790697674, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI1787970, Length=460, Percent_Identity=26.7391304347826, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789175, Length=330, Percent_Identity=29.6969696969697, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI48994898, Length=169, Percent_Identity=27.2189349112426, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25143064, Length=219, Percent_Identity=23.7442922374429, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20129463, Length=239, Percent_Identity=25.9414225941423, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 50304; Mature: 50172

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPSTKESDMEALDLKWIRGQFPALTQKINGQPAIFFDGPGGTQVPGSVLDAISDYLVR
CCCCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHH
SNANAHGAFATSARTDALIIAARTAIADFLGCHSDEVVFGANMTTLTFTLSRAIGRTLQP
CCCCCCCCEEECCCCCEEEEEHHHHHHHHHCCCCCCEEECCCCHHHHEEHHHHHCCCCCC
GDEIIVTRLDHSANVSSWEALAEQGAVIRYVDVKVDDCTLDINDLEQQINSRTKLVAVSY
CCCEEEEEECCCCCCHHHHHHHHCCCEEEEEEEEECCEEECHHHHHHHHCCCCEEEEEEE
ASNAVGTINDIATIVKLAHSVGALVFVDAVHYAPHGPINVHALGCDFLACSAYKFFAPHV
CCCCCCCHHHHHHHHHHHHHHCHHHEEEHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCC
GILYGKREHLANLQPYKVKPAPNEVPSRWETGTLNYEGLAGVVAAVNYLAKLGCHVSPTV
EEEECCHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCH
DQELVSALIEADKEGLEHFHCPRFLTSAEQPSHEIASAYHSRRAAIVAAMSAIQQYEREL
HHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYKLISGLLEIPGLTLYGITDPERFAWRTPTVAIRLQGKSPESIARTLGDRGIFSWHGNF
HHHHHHHHHHCCCEEEEECCCCHHHEECCCEEEEEECCCCHHHHHHHHCCCCEEEECCCE
YALNLTEKLGVESNGGLLRLGLVHYNSVEEIIQLLQALKEIGLD
EEEEEHHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STPSTKESDMEALDLKWIRGQFPALTQKINGQPAIFFDGPGGTQVPGSVLDAISDYLVR
CCCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHH
SNANAHGAFATSARTDALIIAARTAIADFLGCHSDEVVFGANMTTLTFTLSRAIGRTLQP
CCCCCCCCEEECCCCCEEEEEHHHHHHHHHCCCCCCEEECCCCHHHHEEHHHHHCCCCCC
GDEIIVTRLDHSANVSSWEALAEQGAVIRYVDVKVDDCTLDINDLEQQINSRTKLVAVSY
CCCEEEEEECCCCCCHHHHHHHHCCCEEEEEEEEECCEEECHHHHHHHHCCCCEEEEEEE
ASNAVGTINDIATIVKLAHSVGALVFVDAVHYAPHGPINVHALGCDFLACSAYKFFAPHV
CCCCCCCHHHHHHHHHHHHHHCHHHEEEHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCC
GILYGKREHLANLQPYKVKPAPNEVPSRWETGTLNYEGLAGVVAAVNYLAKLGCHVSPTV
EEEECCHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCH
DQELVSALIEADKEGLEHFHCPRFLTSAEQPSHEIASAYHSRRAAIVAAMSAIQQYEREL
HHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYKLISGLLEIPGLTLYGITDPERFAWRTPTVAIRLQGKSPESIARTLGDRGIFSWHGNF
HHHHHHHHHHCCCEEEEECCCCHHHEECCCEEEEEECCCCHHHHHHHHCCCCEEEECCCE
YALNLTEKLGVESNGGLLRLGLVHYNSVEEIIQLLQALKEIGLD
EEEEEHHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]