Click here to switch to the map view.

The map label for this gene is mutT [C]

Identifier: 17231304

GI number: 17231304

Start: 4609557

End: 4609889

Strand: Direct

Name: mutT [C]

Synonym: alr3812

Alternate gene names: 17231304

Gene position: 4609557-4609889 (Clockwise)

Preceding gene: 17231303

Following gene: 17231305

Centisome position: 71.87

GC content: 44.44

Gene sequence:

>333_bases
GTGATGGGGGGTTTGTGGGAATTTCCTGGCGGGAAAATCGAACCAGGGGAGACCGTGGAAGAGTGTATTCAACGAGAGAT
TTATGAAGAGCTAGGGATATTTATTGAAGTGGGTGAATGTCTCATAACTATTGATCACACTTATACTCACTTGCGTGTTA
CTTTGACAGTGCATCATTGTCGCTTACTGAAAGGTATTCCTCAGCCTCTAGAATGTGACGAAGTTCGCTGGGTAACTGTA
GATGAGCTAGAAGACTTTACATTTCCTGAGGCGAATAGTGAAATTATTGCTGCATTGAAGGGAGTGGGGGAGATGAGGAC
TGTTGACGGTTGA

Upstream 100 bases:

>100_bases
TATGAACACAACCACTACTCCACCACACAAAATTATCGGTGTTGCTGTCATTTGGAACGACCAGCAGCAAATATTAATTG
ACCGCCGTCGTCCAGGGGGG

Downstream 100 bases:

>100_bases
CAGTCATCAGTCAACCGTCAACCGTCAACCGTCAACTGTTAACTGTTAACTGTCCAATACCGTAACAATCTATTAACCAA
ATTCAGTAGAGTACCTGAAT

Product: mutator MutT protein

Products: NA

Alternate protein names: NUDIX Hydrolase; A/G-Specific Adenine Glycosylase; Mutator Protein MutT; Nucleoside Triphosphate Pyrophosphohydrolase; NTP Pyrophosphohydrolase; Hydrolase NUDIX Family; Mutator MutT; 7 8-Dihydro-8-Oxoguanine-Triphosphatase; Adenine Glycosylase; A/G-Specific DNA Glycosylase; A/G-Specific DNA-Adenine Glycosylase; Mutator Protein; NUDIX Family Hydrolase; MutT/Nudix Family Protein; 7 8-Dihydro-8-Oxoguanine Triphosphatase; CTP Pyrophosphohydrolase; Hydrolase Nudix Family; Nudix Family Protein MutT Subfamily; MutT-Like Protein; ADP-Ribose Pyrophosphatase; (Di)Nucleoside Polyphosphate Hydrolase; Nudix Hydrolase Protein; NTP Pyrophosphohydrolase MutT Family; Acetyltransferase; Pyrophosphohydrolase; NUDIX Domain-Containing Protein; Mutator Mutt Protein; A/G Specific Adenine Glycosylase; MutT Pyrophosphohydrolase; NTP Pyrophosphohydrolase Including Oxidative Damage Repair; Thiamine Monophosphate Synthase; Radical SAM Domain-Containing Protein; MutT Protein; 78-Dihydro-8-Oxoguanine-Triphosphatase Prefers DGTP; 8-Oxo-DGTPase; Nudix Family Protein Mutt Subfamily; NTP Pyrophosphohydrolase Protein; A/G-Specific DNA Glycosylase MutY; Nudix/MutT Family Protein

Number of amino acids: Translated: 110; Mature: 110

Protein sequence:

>110_residues
MMGGLWEFPGGKIEPGETVEECIQREIYEELGIFIEVGECLITIDHTYTHLRVTLTVHHCRLLKGIPQPLECDEVRWVTV
DELEDFTFPEANSEIIAALKGVGEMRTVDG

Sequences:

>Translated_110_residues
MMGGLWEFPGGKIEPGETVEECIQREIYEELGIFIEVGECLITIDHTYTHLRVTLTVHHCRLLKGIPQPLECDEVRWVTV
DELEDFTFPEANSEIIAALKGVGEMRTVDG
>Mature_110_residues
MMGGLWEFPGGKIEPGETVEECIQREIYEELGIFIEVGECLITIDHTYTHLRVTLTVHHCRLLKGIPQPLECDEVRWVTV
DELEDFTFPEANSEIIAALKGVGEMRTVDG

Specific function: Involved In The Go System Responsible For Removing An Oxidatively Damaged Form Of Guanine (7,8-Dihydro-8-Oxoguanine) From DNA And The Nucleotide Pool. 8-Oxo-Dgtp Is Inserted Opposite Da And Dc Residues Of Template DNA With Almost Equal Efficiency Thus Le

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.2.-

Molecular weight: Translated: 12445; Mature: 12445

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGGLWEFPGGKIEPGETVEECIQREIYEELGIFIEVGECLITIDHTYTHLRVTLTVHHC
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECEEEEEECCCEEEEEEEEEHHHH
RLLKGIPQPLECDEVRWVTVDELEDFTFPEANSEIIAALKGVGEMRTVDG
HHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCEECCCC
>Mature Secondary Structure
MMGGLWEFPGGKIEPGETVEECIQREIYEELGIFIEVGECLITIDHTYTHLRVTLTVHHC
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECEEEEEECCCEEEEEEEEEHHHH
RLLKGIPQPLECDEVRWVTVDELEDFTFPEANSEIIAALKGVGEMRTVDG
HHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA