Click here to switch to the map view.

The map label for this gene is phoB [C]

Identifier: 17231280

GI number: 17231280

Start: 4578406

End: 4579122

Strand: Reverse

Name: phoB [C]

Synonym: all3788

Alternate gene names: 17231280

Gene position: 4579122-4578406 (Counterclockwise)

Preceding gene: 17231283

Following gene: 17231279

Centisome position: 71.4

GC content: 41.0

Gene sequence:

>717_bases
ATGGTGATGCTTTCCGCTACAAACCCCAAAATTCTTGTTGTAGATGACGATTTTGGAGTCCGTAACCTCATATATCGCTT
TTTAAGCCGCAAATATCAAATAGAGTCTGCGGCAGATGGTAAAACAGCTTTGTCATTGTTTGAGCAATTTAACCCAGCCT
TGGTGATTCTTGATTGGAATCTTCCAGACACCAGTGGCTACAGTCTTTGCCAAGAAATGCAGAGCCGTAATAACGTCTTG
GTGATGATCTTGACTGGAAGAACAGAGGAAGCTGACAAAATTAGAATCCTGGCTGCTGGTGCTGATGACTTCATTACGAA
GCCATTTAGTTTGGCTGAAATTGAAGTTCGCGTCCAAGCTCTTTTAAGACGTATCCGCTCTATTAAACCTTCTCCTTCAC
AACGCTTGATATTTAAGCAGTTAGCAATTAACCCAGAAGGAAGAGAGGTAACTCTTAACGATAAACCTCTGAATCTCACC
GCTTTGGAGTTTAATATTCTCCATTTCTTAGCTAGTCATCCTGGTCAAGCTTGGAGCCGTCCTCAATTAATTCAAAAAAT
TTGGGGTTGTGACTATGTAGGAGATGGACGGGTGGTTGACGTACACATCGGACAACTACGTAAGAAGTTAGAATCTGATA
CCAGTATACCGGAGTTTATTAAAACTGTTCGCGGTTACGGTTATAAGTTTGAAATACCAGAATCTACAGCAATTTAA

Upstream 100 bases:

>100_bases
GCTCATAACACAATCACCTTAACGGCTGTCTCTTGTGTAGGAGCATAACAAACAGCAAAACGCTAGATAAACAATAGGCC
ATAACAATCGCTGAAACAAT

Downstream 100 bases:

>100_bases
GCTGGGAAAGCAAGAGTTTACCTGATCAAAAAGTTAACTCACACACTTCTATCAGGGTGTGGCTATTTAAAATTTGACTG
TTTATTTACATCTTCTTTTT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MVMLSATNPKILVVDDDFGVRNLIYRFLSRKYQIESAADGKTALSLFEQFNPALVILDWNLPDTSGYSLCQEMQSRNNVL
VMILTGRTEEADKIRILAAGADDFITKPFSLAEIEVRVQALLRRIRSIKPSPSQRLIFKQLAINPEGREVTLNDKPLNLT
ALEFNILHFLASHPGQAWSRPQLIQKIWGCDYVGDGRVVDVHIGQLRKKLESDTSIPEFIKTVRGYGYKFEIPESTAI

Sequences:

>Translated_238_residues
MVMLSATNPKILVVDDDFGVRNLIYRFLSRKYQIESAADGKTALSLFEQFNPALVILDWNLPDTSGYSLCQEMQSRNNVL
VMILTGRTEEADKIRILAAGADDFITKPFSLAEIEVRVQALLRRIRSIKPSPSQRLIFKQLAINPEGREVTLNDKPLNLT
ALEFNILHFLASHPGQAWSRPQLIQKIWGCDYVGDGRVVDVHIGQLRKKLESDTSIPEFIKTVRGYGYKFEIPESTAI
>Mature_238_residues
MVMLSATNPKILVVDDDFGVRNLIYRFLSRKYQIESAADGKTALSLFEQFNPALVILDWNLPDTSGYSLCQEMQSRNNVL
VMILTGRTEEADKIRILAAGADDFITKPFSLAEIEVRVQALLRRIRSIKPSPSQRLIFKQLAINPEGREVTLNDKPLNLT
ALEFNILHFLASHPGQAWSRPQLIQKIWGCDYVGDGRVVDVHIGQLRKKLESDTSIPEFIKTVRGYGYKFEIPESTAI

Specific function: This Protein Is A Positive Regulator For The Phosphate Regulon. Transcription Of This Operon Is Positively Regulated By Phob And Phor When Phosphate Is Limited. [C]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=37.1681415929204, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=37.4468085106383, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=35.0649350649351, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1788394, Length=234, Percent_Identity=34.6153846153846, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=35.8744394618834, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=33.7777777777778, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=31.4159292035398, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=33.6322869955157, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=29.3859649122807, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=32.1739130434783, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=32.8888888888889, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=31.8385650224215, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=34.3891402714932, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787229, Length=207, Percent_Identity=31.8840579710145, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1788550, Length=128, Percent_Identity=32.8125, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26920; Mature: 26920

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMLSATNPKILVVDDDFGVRNLIYRFLSRKYQIESAADGKTALSLFEQFNPALVILDWN
CEEEECCCCEEEEEECCCCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHCCCEEEEEECC
LPDTSGYSLCQEMQSRNNVLVMILTGRTEEADKIRILAAGADDFITKPFSLAEIEVRVQA
CCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEEECCHHHHCCCCCHHHHHHHHHH
LLRRIRSIKPSPSQRLIFKQLAINPEGREVTLNDKPLNLTALEFNILHFLASHPGQAWSR
HHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCEEEEHHHHHHHHHHCCCCCCCCC
PQLIQKIWGCDYVGDGRVVDVHIGQLRKKLESDTSIPEFIKTVRGYGYKFEIPESTAI
HHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCCCCC
>Mature Secondary Structure
MVMLSATNPKILVVDDDFGVRNLIYRFLSRKYQIESAADGKTALSLFEQFNPALVILDWN
CEEEECCCCEEEEEECCCCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHCCCEEEEEECC
LPDTSGYSLCQEMQSRNNVLVMILTGRTEEADKIRILAAGADDFITKPFSLAEIEVRVQA
CCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEEECCHHHHCCCCCHHHHHHHHHH
LLRRIRSIKPSPSQRLIFKQLAINPEGREVTLNDKPLNLTALEFNILHFLASHPGQAWSR
HHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCEEEEHHHHHHHHHHCCCCCCCCC
PQLIQKIWGCDYVGDGRVVDVHIGQLRKKLESDTSIPEFIKTVRGYGYKFEIPESTAI
HHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1554697 [H]