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The map label for this gene is obgE [H]

Identifier: 17231231

GI number: 17231231

Start: 4515106

End: 4516134

Strand: Direct

Name: obgE [H]

Synonym: alr3739

Alternate gene names: 17231231

Gene position: 4515106-4516134 (Clockwise)

Preceding gene: 17231230

Following gene: 17231234

Centisome position: 70.4

GC content: 44.9

Gene sequence:

>1029_bases
ATGCAATTTATCGACCAAGCACAAATCGAAGTAGAAGCTGGTAAAGGTGGCGATGGTATCGTCGCTTTCCGGCGTGAAAA
ATATGTACCCGCCGGTGGGCCTTCTGGTGGGAATGGCGGACGAGGTGGTTCAGTCATTTTCGTTGCGGTGGAAAATCTAC
AAACCCTGTTAGACTTCCGATATAAGCATATATTTAAAGCAGACGATGGCGGTCGTGGCGGCCCCAATAACTGTACAGGC
GCTTCCGGGAAAGATTTAATCGTCCAGGTTCCCTGTGGAACCACTATTTATGATGCAGAAACGGGTGATTTACTTGGTGA
TTTAACTCAACCTAACCAAGAACTAATCATTGCAGCAGGTGGTAAAGGTGGTTTGGGAAATCAATACTTCTTGAGTAACC
GTAACCGCGCCCCAGAATACTCGCTCCCAGGATTACCAGGGGAAAGAAAGCTGCTCCGTTTAGAGTTGAAATTATTGGCA
GAAGTAGGAATTATCGGTTTACCTAATGCAGGTAAATCAACTTTAATATCATCTTTATCGGCGGCGCGTCCGAAAATTGC
TGATTATCCCTTTACAACCCTCATCCCCAACTTGGGTGTAGTGCGGAAACCTACAGGTGATGGTACAGTCTTTGCCGATA
TCCCTGGCTTAATTGAAGGTGCAGCCGACGGTGCAGGGTTGGGACATGACTTTTTGCGTCACATTGAAAGGACACGGGTA
CTTCTGCACTTAATTGATGCTACTAGTGATGATGTTATCAGAGACTACAACACAATTGAGCAGGAATTGCAAGCTTACGG
ACGAGGTTTAAATGAGCGAATGCAGATTTTAGCGCTGAATAAAATTGATGCAGTTGATCGGGAAACTGTAGACTTAGAAG
CACTAGCCATCCAATTAAATCATCTTTCTCACGCCCCTGTGTTCTTAATTTCTGCGGTAACTCGCACTGGGTTAGAACCA
ATGTTACAAGAAGTTTGGGGAATTCTTGACCAAGTAAATGCTCTGGAAGAAGCAGAAGTTTTTAGTTAG

Upstream 100 bases:

>100_bases
CGTTGTGAAGAAGACATCATGATCAATGGAAAGCATTCCAACGAACGAATAACCAATAAGCATTGACGACTGACAACTGA
CTACTGACAATTGACGAATT

Downstream 100 bases:

>100_bases
CAGCAAAATAGCGAGTGGTTCGTAAAAAACTCTGCGTACCTCCGCGCTACCCAGCCTGCGGCTTGCCGCAAAAGCGTCTA
CCGCCTTCCTCTGCGTTTAA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MQFIDQAQIEVEAGKGGDGIVAFRREKYVPAGGPSGGNGGRGGSVIFVAVENLQTLLDFRYKHIFKADDGGRGGPNNCTG
ASGKDLIVQVPCGTTIYDAETGDLLGDLTQPNQELIIAAGGKGGLGNQYFLSNRNRAPEYSLPGLPGERKLLRLELKLLA
EVGIIGLPNAGKSTLISSLSAARPKIADYPFTTLIPNLGVVRKPTGDGTVFADIPGLIEGAADGAGLGHDFLRHIERTRV
LLHLIDATSDDVIRDYNTIEQELQAYGRGLNERMQILALNKIDAVDRETVDLEALAIQLNHLSHAPVFLISAVTRTGLEP
MLQEVWGILDQVNALEEAEVFS

Sequences:

>Translated_342_residues
MQFIDQAQIEVEAGKGGDGIVAFRREKYVPAGGPSGGNGGRGGSVIFVAVENLQTLLDFRYKHIFKADDGGRGGPNNCTG
ASGKDLIVQVPCGTTIYDAETGDLLGDLTQPNQELIIAAGGKGGLGNQYFLSNRNRAPEYSLPGLPGERKLLRLELKLLA
EVGIIGLPNAGKSTLISSLSAARPKIADYPFTTLIPNLGVVRKPTGDGTVFADIPGLIEGAADGAGLGHDFLRHIERTRV
LLHLIDATSDDVIRDYNTIEQELQAYGRGLNERMQILALNKIDAVDRETVDLEALAIQLNHLSHAPVFLISAVTRTGLEP
MLQEVWGILDQVNALEEAEVFS
>Mature_342_residues
MQFIDQAQIEVEAGKGGDGIVAFRREKYVPAGGPSGGNGGRGGSVIFVAVENLQTLLDFRYKHIFKADDGGRGGPNNCTG
ASGKDLIVQVPCGTTIYDAETGDLLGDLTQPNQELIIAAGGKGGLGNQYFLSNRNRAPEYSLPGLPGERKLLRLELKLLA
EVGIIGLPNAGKSTLISSLSAARPKIADYPFTTLIPNLGVVRKPTGDGTVFADIPGLIEGAADGAGLGHDFLRHIERTRV
LLHLIDATSDDVIRDYNTIEQELQAYGRGLNERMQILALNKIDAVDRETVDLEALAIQLNHLSHAPVFLISAVTRTGLEP
MLQEVWGILDQVNALEEAEVFS

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=338, Percent_Identity=39.9408284023669, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI111955139, Length=298, Percent_Identity=36.9127516778523, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI111955063, Length=129, Percent_Identity=44.1860465116279, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI58761500, Length=130, Percent_Identity=35.3846153846154, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI4557537, Length=161, Percent_Identity=32.2981366459627, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4758796, Length=124, Percent_Identity=34.6774193548387, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1789574, Length=328, Percent_Identity=49.390243902439, Blast_Score=279, Evalue=2e-76,
Organism=Escherichia coli, GI1787454, Length=109, Percent_Identity=39.4495412844037, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17508313, Length=333, Percent_Identity=38.4384384384384, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17552324, Length=320, Percent_Identity=29.0625, Blast_Score=120, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17509631, Length=191, Percent_Identity=29.8429319371728, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71981008, Length=162, Percent_Identity=31.4814814814815, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17555344, Length=114, Percent_Identity=34.2105263157895, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=201, Percent_Identity=38.3084577114428, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6319281, Length=114, Percent_Identity=35.9649122807018, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321612, Length=162, Percent_Identity=31.4814814814815, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129375, Length=326, Percent_Identity=37.7300613496933, Blast_Score=167, Evalue=9e-42,
Organism=Drosophila melanogaster, GI24585318, Length=296, Percent_Identity=36.8243243243243, Blast_Score=144, Evalue=9e-35,
Organism=Drosophila melanogaster, GI21356473, Length=161, Percent_Identity=33.5403726708075, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17981711, Length=114, Percent_Identity=34.2105263157895, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 36589; Mature: 36589

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFIDQAQIEVEAGKGGDGIVAFRREKYVPAGGPSGGNGGRGGSVIFVAVENLQTLLDFR
CCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHH
YKHIFKADDGGRGGPNNCTGASGKDLIVQVPCGTTIYDAETGDLLGDLTQPNQELIIAAG
HHHHEECCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCHHHHCCCCCCCEEEEEEC
GKGGLGNQYFLSNRNRAPEYSLPGLPGERKLLRLELKLLAEVGIIGLPNAGKSTLISSLS
CCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHH
AARPKIADYPFTTLIPNLGVVRKPTGDGTVFADIPGLIEGAADGAGLGHDFLRHIERTRV
HCCCCCCCCCHHHHCCCCCEEECCCCCCEEEECCCHHHHCCCCCCCCCHHHHHHHHHHHH
LLHLIDATSDDVIRDYNTIEQELQAYGRGLNERMQILALNKIDAVDRETVDLEALAIQLN
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHEEEEEECCCCCCCCCCCCHHHEEEEHH
HLSHAPVFLISAVTRTGLEPMLQEVWGILDQVNALEEAEVFS
CCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQFIDQAQIEVEAGKGGDGIVAFRREKYVPAGGPSGGNGGRGGSVIFVAVENLQTLLDFR
CCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHH
YKHIFKADDGGRGGPNNCTGASGKDLIVQVPCGTTIYDAETGDLLGDLTQPNQELIIAAG
HHHHEECCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCHHHHCCCCCCCEEEEEEC
GKGGLGNQYFLSNRNRAPEYSLPGLPGERKLLRLELKLLAEVGIIGLPNAGKSTLISSLS
CCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHH
AARPKIADYPFTTLIPNLGVVRKPTGDGTVFADIPGLIEGAADGAGLGHDFLRHIERTRV
HCCCCCCCCCHHHHCCCCCEEECCCCCCEEEECCCHHHHCCCCCCCCCHHHHHHHHHHHH
LLHLIDATSDDVIRDYNTIEQELQAYGRGLNERMQILALNKIDAVDRETVDLEALAIQLN
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHEEEEEECCCCCCCCCCCCHHHEEEEHH
HLSHAPVFLISAVTRTGLEPMLQEVWGILDQVNALEEAEVFS
CCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA