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The map label for this gene is cobL [H]

Identifier: 17231214

GI number: 17231214

Start: 4492537

End: 4493748

Strand: Reverse

Name: cobL [H]

Synonym: all3722

Alternate gene names: 17231214

Gene position: 4493748-4492537 (Counterclockwise)

Preceding gene: 17231218

Following gene: 17231213

Centisome position: 70.06

GC content: 46.12

Gene sequence:

>1212_bases
ATGACGCAGAAATGGCTATCTATTATCGGTATTGGTGAAGATGGATTATTGGGGTTAAGTGCGATCGCTATTTCTCTACT
CAATCAAGCGGAAATCGTTGTAGGAGGCGATCGCCATTTAGCAATGTTACCTCCAAACGACCCACGGGAAAAAATCCTCT
GGACTTCTCCTATTACTACCGCAGTGGCAGAAATTATCCAGCGTCGGGGTAAATCTGTATGTGTGTTAGCCAGTGGTGAT
CCCATGTATTACGGTATTGGTGTCACCTTGGCGCGACAAATTTCCATATCCGAAATGACAATTATCCCCGCACCTTCATC
TTTTAGCCTGGCCTGCGCCCGATTAGGATGGTCTTTAACGGAGGTAGAAACCTTGAGTTTATGCGGTCGTCCCTCGGCTT
TGCTGCAATCTTACATATATCCTGGTGCGCGGTTATTAATTTTGAGTGAGGGGAAAAATACACCGAGTATTGTTGCTGAA
ACCCTCACACAGCGAGGTTTTGGGAATAGCCAACTCACAGTTTTGGAACGGATGGGCGGTATTCATGAAAGGATATTAAC
AGGGATAGCTGCAACTTGGCAGGAAACAGAACTGGCAGATTTAAATGCGATCGCTGTACACTGTATCGTCGATACTGGTG
TTGTCGCCTTACCCAGATTACCAGGATTACCAGATAGCGTTTATCACCACGACGGACAACTTACCAAACGGGAAGTTAGA
GCAGTTACCCTATCAACTTTAGCACCCACACCAGGACAGTTACTTTGGGATGTGGGGGCGGGTTGTGGTTCCATATCAAT
AGAATGGATGCGGACTAATCCCAGATGTCAGGCGATCGCCATTGAACAAAACTCATCTAGACTACAATACATTGCAGATA
ATGCGGCTGCTTTAGGTACTCCCAACCTGAAAATTGTTGCAGGAAAAGCACCTCACATCCTCCAAGACTTACCCACACCC
GATGCCATTTTTATCGGTGGTGGAGTTACAGCCACAGGATTGTTTGATATTTGTTGGCAAGCACTACGCCCAGGCGGTAG
GTTAATTGCTAATGTAGTCACCATAGAAGGTGAGCAGACTTTATTTCAATGGTACGAAAAAGTGGGTGGCAGTTTCACCC
GTATTGCCATTCAACGAGCCGAACCAATTGGTAAATTTTTGGGTTGGCGAGCAATGGCTACTGTCACACAATGGGTAGCG
GTGAAAGATTGA

Upstream 100 bases:

>100_bases
GTGATGGAAAAGTGATAGTAAATTAAGAAGGGTCAAGGGTTTTGCTTTCAAATTAAAATTTTTTATGACAAGTGCTAACA
GATTCAATTTTGGGTAGCTT

Downstream 100 bases:

>100_bases
AGAAGACAAGGACTAAGGCAACTTTAGACCGGGTGTAAGGGTTTAGGGGTGTAAGGATGTAAGGGAAGAATTTAGTTTTA
CTCTTTCCCCTGAACCCCTA

Product: precorrin-6y-dependent methyltransferase

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MTQKWLSIIGIGEDGLLGLSAIAISLLNQAEIVVGGDRHLAMLPPNDPREKILWTSPITTAVAEIIQRRGKSVCVLASGD
PMYYGIGVTLARQISISEMTIIPAPSSFSLACARLGWSLTEVETLSLCGRPSALLQSYIYPGARLLILSEGKNTPSIVAE
TLTQRGFGNSQLTVLERMGGIHERILTGIAATWQETELADLNAIAVHCIVDTGVVALPRLPGLPDSVYHHDGQLTKREVR
AVTLSTLAPTPGQLLWDVGAGCGSISIEWMRTNPRCQAIAIEQNSSRLQYIADNAAALGTPNLKIVAGKAPHILQDLPTP
DAIFIGGGVTATGLFDICWQALRPGGRLIANVVTIEGEQTLFQWYEKVGGSFTRIAIQRAEPIGKFLGWRAMATVTQWVA
VKD

Sequences:

>Translated_403_residues
MTQKWLSIIGIGEDGLLGLSAIAISLLNQAEIVVGGDRHLAMLPPNDPREKILWTSPITTAVAEIIQRRGKSVCVLASGD
PMYYGIGVTLARQISISEMTIIPAPSSFSLACARLGWSLTEVETLSLCGRPSALLQSYIYPGARLLILSEGKNTPSIVAE
TLTQRGFGNSQLTVLERMGGIHERILTGIAATWQETELADLNAIAVHCIVDTGVVALPRLPGLPDSVYHHDGQLTKREVR
AVTLSTLAPTPGQLLWDVGAGCGSISIEWMRTNPRCQAIAIEQNSSRLQYIADNAAALGTPNLKIVAGKAPHILQDLPTP
DAIFIGGGVTATGLFDICWQALRPGGRLIANVVTIEGEQTLFQWYEKVGGSFTRIAIQRAEPIGKFLGWRAMATVTQWVA
VKD
>Mature_402_residues
TQKWLSIIGIGEDGLLGLSAIAISLLNQAEIVVGGDRHLAMLPPNDPREKILWTSPITTAVAEIIQRRGKSVCVLASGDP
MYYGIGVTLARQISISEMTIIPAPSSFSLACARLGWSLTEVETLSLCGRPSALLQSYIYPGARLLILSEGKNTPSIVAET
LTQRGFGNSQLTVLERMGGIHERILTGIAATWQETELADLNAIAVHCIVDTGVVALPRLPGLPDSVYHHDGQLTKREVRA
VTLSTLAPTPGQLLWDVGAGCGSISIEWMRTNPRCQAIAIEQNSSRLQYIADNAAALGTPNLKIVAGKAPHILQDLPTPD
AIFIGGGVTATGLFDICWQALRPGGRLIANVVTIEGEQTLFQWYEKVGGSFTRIAIQRAEPIGKFLGWRAMATVTQWVAV
KD

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 43289; Mature: 43157

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKWLSIIGIGEDGLLGLSAIAISLLNQAEIVVGGDRHLAMLPPNDPREKILWTSPITT
CCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCCEEEECCCCCCHHCEEEECCHHH
AVAEIIQRRGKSVCVLASGDPMYYGIGVTLARQISISEMTIIPAPSSFSLACARLGWSLT
HHHHHHHHCCCEEEEEECCCCEEEEECEEEEEEEEEEEEEEEECCCCHHHHHHHHCCCHH
EVETLSLCGRPSALLQSYIYPGARLLILSEGKNTPSIVAETLTQRGFGNSQLTVLERMGG
HHHHHHHCCCCHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHCC
IHERILTGIAATWQETELADLNAIAVHCIVDTGVVALPRLPGLPDSVYHHDGQLTKREVR
HHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCEEEECCCCCCCCHHHCCCCCCCHHHHE
AVTLSTLAPTPGQLLWDVGAGCGSISIEWMRTNPRCQAIAIEQNSSRLQYIADNAAALGT
EEEEECCCCCCCCEEEECCCCCCCEEEEEEECCCCEEEEEEECCCCEEEEEECCCCCCCC
PNLKIVAGKAPHILQDLPTPDAIFIGGGVTATGLFDICWQALRPGGRLIANVVTIEGEQT
CCEEEEECCCCHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCHH
LFQWYEKVGGSFTRIAIQRAEPIGKFLGWRAMATVTQWVAVKD
HHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHEEECC
>Mature Secondary Structure 
TQKWLSIIGIGEDGLLGLSAIAISLLNQAEIVVGGDRHLAMLPPNDPREKILWTSPITT
CCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCCEEEECCCCCCHHCEEEECCHHH
AVAEIIQRRGKSVCVLASGDPMYYGIGVTLARQISISEMTIIPAPSSFSLACARLGWSLT
HHHHHHHHCCCEEEEEECCCCEEEEECEEEEEEEEEEEEEEEECCCCHHHHHHHHCCCHH
EVETLSLCGRPSALLQSYIYPGARLLILSEGKNTPSIVAETLTQRGFGNSQLTVLERMGG
HHHHHHHCCCCHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHCC
IHERILTGIAATWQETELADLNAIAVHCIVDTGVVALPRLPGLPDSVYHHDGQLTKREVR
HHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCEEEECCCCCCCCHHHCCCCCCCHHHHE
AVTLSTLAPTPGQLLWDVGAGCGSISIEWMRTNPRCQAIAIEQNSSRLQYIADNAAALGT
EEEEECCCCCCCCEEEECCCCCCCEEEEEEECCCCEEEEEEECCCCEEEEEECCCCCCCC
PNLKIVAGKAPHILQDLPTPDAIFIGGGVTATGLFDICWQALRPGGRLIANVVTIEGEQT
CCEEEEECCCCHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCHH
LFQWYEKVGGSFTRIAIQRAEPIGKFLGWRAMATVTQWVAVKD
HHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]