Click here to switch to the map view.

The map label for this gene is argS [H]

Identifier: 17231209

GI number: 17231209

Start: 4488053

End: 4489819

Strand: Reverse

Name: argS [H]

Synonym: all3717

Alternate gene names: 17231209

Gene position: 4489819-4488053 (Counterclockwise)

Preceding gene: 17231211

Following gene: 17231205

Centisome position: 70.0

GC content: 41.94

Gene sequence:

>1767_bases
ATGAACGCTACACAAGAACAACTAAAGATAAAACTTGAGCAGGCTTTGGTTGCTGCTTTTGGCGATGAGTACGCCGGAGT
AGACCCGATTTTGGTTTCTGCTAGCAATCCTAAGTTTGGTGATTATCAAGCCAACGTTGCTTTATCGTTGAGTAAAAAGT
TAGGACAGCAACCGCGAGCGATCGCCTCTGCTATTGTAGAAAAACTAGATGTATCAGAAATTTGCGAAAAACCAGAAATT
GCTGGGCCTGGTTTTATTAACCTGAAGTTGAAAACCGCCTACCTAGAAGCGCAACTAAACACTATTCAAGCAGATACCAG
ACTAGGCGTTCCTACCGCCAAACACCCACAACGGGAAATCGTCGATTTTTCTAGTCCGAATATCGCCAAAGAGATGCACG
TTGGACACTTGCGTTCTACCATCATCGGTGATTCCATCGCCCGGATTCTTGAATTTCGCGGACATGATGTATTGCGGTTA
AATCATGTGGGTGATTGGGGTACCCAATTTGGGATGTTAATTACTTACCTGCGGGAAGTTTCCCCAGAAGCCTTAACTAC
TGCTAATGCTTTAGATATCGGTGATTTGGTGAGTTTTTATCGTCAAGCCAAGCAACGGTTTGATGCTGATGAAGCCTTCC
AAGAGACAGCGCGCCAAGAAGTTGTTAGATTACAAGCCGGCGCAGCAGATACCCTCCATGCTTGGAAGTTGTTGTGTGAA
CAATCACGCCAAGAGTTTCAGGTAATTTATGATTTGTTAGATGTCAAATTAACTGAACGAGGCGAATCTTTTTATAACCC
CTTACTACCAACTGTTGTAGAAAATTTAGAGAAATCTGGTTTATTGGTAGAAAACCAAGGTGCAAAATGCGTTTTCTTAG
ATGGCTTTACTAATAGAGAAGGTGAACCTCTACCCTTGATTGTGCAGAAATCTGATGGTGGTTATAACTACGCTACAACA
GATTTAGCTGCGTTACGTTACCGGATTCAAAAAGATGAAGCCAAACGCATTATTTATATCACCGATGCGGGACAAGCCAA
CCACTTTGCCCAATTCTTTCAAGTAGCACGTAAAGCCGGATGGATTCCTGATGATGTGGAATTGGTTCACGTCCCCTTTG
GTTTGGTGTTGGGTGAAGATGGGAAAAAATTTAAAACTCGTTCCGGTGATACTGTGCGGCTACGAGATTTATTAGATGAA
GCAATTTCTCGCGCCCATGCAGATGTAGAAGTAAGATTAAAAGCAGAAGAACGAGAAGAAACCGCAGAATTTATCGATAA
AGTTGCGGAAGTAGTTGGTATTAGTGCAGTAAAATACGCTGACTTAAGTCAAAATCGCACCAGTAACTACATTTTCAGCT
ACGACAAAATGCTGGATTTGAAAGGCAATACAGCACCATATATGTTGTATGCTTATGCTCGGATTCAAGGGATTAGCCGT
AAGGGAGAGATTAACTTTGCAGATTTGGGAGATAATGCCAAAGTCATCCTGCAACATGAAACAGAATTTGCTCTAGCTAA
ATACCTACTGCAACTAGGTGAAGTGATTAGTACTGTAGAAGAAGACTTATCACCTAACCGTTTATGTGAGTATTTGTATG
AATTGAGTAAACGCTTTAATGCGTTTTATGACCGCAATCAAGGGGTGCAGGTTTTAAGTGCAGAGGAACCATTGCGGACA
TCCCGTTTAGTTCTGTGTGATTTGACAGCTAGAACTTTAAAACTCGGCTTATCATTGTTGGGTATTCAGGTGCTTGAACG
GATGTAA

Upstream 100 bases:

>100_bases
TGAGATTAGCTGACTATATTTTAAGGTTAAAATAATCAAGCCCTTGAGAATATCCAACACTCAACAGCCGCATTCCGCCT
GTGACAGATAACATTTATAT

Downstream 100 bases:

>100_bases
TTAAAGGCTATTGATAAAGTAAATCTAGAAGCGAGAAGAAAAGAGTTAGCGTAAGTATAAGTTACATCATACACGGTCTA
TTTACATAGAGCGAAGCAGT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MNATQEQLKIKLEQALVAAFGDEYAGVDPILVSASNPKFGDYQANVALSLSKKLGQQPRAIASAIVEKLDVSEICEKPEI
AGPGFINLKLKTAYLEAQLNTIQADTRLGVPTAKHPQREIVDFSSPNIAKEMHVGHLRSTIIGDSIARILEFRGHDVLRL
NHVGDWGTQFGMLITYLREVSPEALTTANALDIGDLVSFYRQAKQRFDADEAFQETARQEVVRLQAGAADTLHAWKLLCE
QSRQEFQVIYDLLDVKLTERGESFYNPLLPTVVENLEKSGLLVENQGAKCVFLDGFTNREGEPLPLIVQKSDGGYNYATT
DLAALRYRIQKDEAKRIIYITDAGQANHFAQFFQVARKAGWIPDDVELVHVPFGLVLGEDGKKFKTRSGDTVRLRDLLDE
AISRAHADVEVRLKAEEREETAEFIDKVAEVVGISAVKYADLSQNRTSNYIFSYDKMLDLKGNTAPYMLYAYARIQGISR
KGEINFADLGDNAKVILQHETEFALAKYLLQLGEVISTVEEDLSPNRLCEYLYELSKRFNAFYDRNQGVQVLSAEEPLRT
SRLVLCDLTARTLKLGLSLLGIQVLERM

Sequences:

>Translated_588_residues
MNATQEQLKIKLEQALVAAFGDEYAGVDPILVSASNPKFGDYQANVALSLSKKLGQQPRAIASAIVEKLDVSEICEKPEI
AGPGFINLKLKTAYLEAQLNTIQADTRLGVPTAKHPQREIVDFSSPNIAKEMHVGHLRSTIIGDSIARILEFRGHDVLRL
NHVGDWGTQFGMLITYLREVSPEALTTANALDIGDLVSFYRQAKQRFDADEAFQETARQEVVRLQAGAADTLHAWKLLCE
QSRQEFQVIYDLLDVKLTERGESFYNPLLPTVVENLEKSGLLVENQGAKCVFLDGFTNREGEPLPLIVQKSDGGYNYATT
DLAALRYRIQKDEAKRIIYITDAGQANHFAQFFQVARKAGWIPDDVELVHVPFGLVLGEDGKKFKTRSGDTVRLRDLLDE
AISRAHADVEVRLKAEEREETAEFIDKVAEVVGISAVKYADLSQNRTSNYIFSYDKMLDLKGNTAPYMLYAYARIQGISR
KGEINFADLGDNAKVILQHETEFALAKYLLQLGEVISTVEEDLSPNRLCEYLYELSKRFNAFYDRNQGVQVLSAEEPLRT
SRLVLCDLTARTLKLGLSLLGIQVLERM
>Mature_588_residues
MNATQEQLKIKLEQALVAAFGDEYAGVDPILVSASNPKFGDYQANVALSLSKKLGQQPRAIASAIVEKLDVSEICEKPEI
AGPGFINLKLKTAYLEAQLNTIQADTRLGVPTAKHPQREIVDFSSPNIAKEMHVGHLRSTIIGDSIARILEFRGHDVLRL
NHVGDWGTQFGMLITYLREVSPEALTTANALDIGDLVSFYRQAKQRFDADEAFQETARQEVVRLQAGAADTLHAWKLLCE
QSRQEFQVIYDLLDVKLTERGESFYNPLLPTVVENLEKSGLLVENQGAKCVFLDGFTNREGEPLPLIVQKSDGGYNYATT
DLAALRYRIQKDEAKRIIYITDAGQANHFAQFFQVARKAGWIPDDVELVHVPFGLVLGEDGKKFKTRSGDTVRLRDLLDE
AISRAHADVEVRLKAEEREETAEFIDKVAEVVGISAVKYADLSQNRTSNYIFSYDKMLDLKGNTAPYMLYAYARIQGISR
KGEINFADLGDNAKVILQHETEFALAKYLLQLGEVISTVEEDLSPNRLCEYLYELSKRFNAFYDRNQGVQVLSAEEPLRT
SRLVLCDLTARTLKLGLSLLGIQVLERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=575, Percent_Identity=46.0869565217391, Blast_Score=487, Evalue=1e-137,
Organism=Homo sapiens, GI197100773, Length=478, Percent_Identity=34.1004184100418, Blast_Score=223, Evalue=6e-58,
Organism=Escherichia coli, GI1788184, Length=589, Percent_Identity=48.5568760611205, Blast_Score=535, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI71985061, Length=595, Percent_Identity=41.5126050420168, Blast_Score=442, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI71985068, Length=577, Percent_Identity=41.7677642980936, Blast_Score=423, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17532153, Length=494, Percent_Identity=25.9109311740891, Blast_Score=125, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6320548, Length=547, Percent_Identity=32.9067641681901, Blast_Score=231, Evalue=3e-61,
Organism=Saccharomyces cerevisiae, GI6321883, Length=595, Percent_Identity=26.7226890756303, Blast_Score=190, Evalue=6e-49,
Organism=Drosophila melanogaster, GI18859963, Length=605, Percent_Identity=42.4793388429752, Blast_Score=465, Evalue=1e-131,
Organism=Drosophila melanogaster, GI28571570, Length=483, Percent_Identity=30.6418219461698, Blast_Score=163, Evalue=4e-40,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 65816; Mature: 65816

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNATQEQLKIKLEQALVAAFGDEYAGVDPILVSASNPKFGDYQANVALSLSKKLGQQPRA
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCEECCEEEEEHHHCCCCHHH
IASAIVEKLDVSEICEKPEIAGPGFINLKLKTAYLEAQLNTIQADTRLGVPTAKHPQREI
HHHHHHHHCCHHHHHCCCCCCCCCEEEEEEEEEEEHHHHHHHCCCCCCCCCCCCCCHHHH
VDFSSPNIAKEMHVGHLRSTIIGDSIARILEFRGHDVLRLNHVGDWGTQFGMLITYLREV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHC
SPEALTTANALDIGDLVSFYRQAKQRFDADEAFQETARQEVVRLQAGAADTLHAWKLLCE
CCHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QSRQEFQVIYDLLDVKLTERGESFYNPLLPTVVENLEKSGLLVENQGAKCVFLDGFTNRE
HHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCC
GEPLPLIVQKSDGGYNYATTDLAALRYRIQKDEAKRIIYITDAGQANHFAQFFQVARKAG
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCC
WIPDDVELVHVPFGLVLGEDGKKFKTRSGDTVRLRDLLDEAISRAHADVEVRLKAEEREE
CCCCCCEEEEECEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCEEEEEECHHHHH
TAEFIDKVAEVVGISAVKYADLSQNRTSNYIFSYDKMLDLKGNTAPYMLYAYARIQGISR
HHHHHHHHHHHHCCHHHEECCCCCCCCCCEEEEECCEEECCCCCCCEEEEEEHHHHCCCC
KGEINFADLGDNAKVILQHETEFALAKYLLQLGEVISTVEEDLSPNRLCEYLYELSKRFN
CCCEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AFYDRNQGVQVLSAEEPLRTSRLVLCDLTARTLKLGLSLLGIQVLERM
HHHCCCCCCEEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNATQEQLKIKLEQALVAAFGDEYAGVDPILVSASNPKFGDYQANVALSLSKKLGQQPRA
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCEECCEEEEEHHHCCCCHHH
IASAIVEKLDVSEICEKPEIAGPGFINLKLKTAYLEAQLNTIQADTRLGVPTAKHPQREI
HHHHHHHHCCHHHHHCCCCCCCCCEEEEEEEEEEEHHHHHHHCCCCCCCCCCCCCCHHHH
VDFSSPNIAKEMHVGHLRSTIIGDSIARILEFRGHDVLRLNHVGDWGTQFGMLITYLREV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHC
SPEALTTANALDIGDLVSFYRQAKQRFDADEAFQETARQEVVRLQAGAADTLHAWKLLCE
CCHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QSRQEFQVIYDLLDVKLTERGESFYNPLLPTVVENLEKSGLLVENQGAKCVFLDGFTNRE
HHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCC
GEPLPLIVQKSDGGYNYATTDLAALRYRIQKDEAKRIIYITDAGQANHFAQFFQVARKAG
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCC
WIPDDVELVHVPFGLVLGEDGKKFKTRSGDTVRLRDLLDEAISRAHADVEVRLKAEEREE
CCCCCCEEEEECEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCEEEEEECHHHHH
TAEFIDKVAEVVGISAVKYADLSQNRTSNYIFSYDKMLDLKGNTAPYMLYAYARIQGISR
HHHHHHHHHHHHCCHHHEECCCCCCCCCCEEEEECCEEECCCCCCCEEEEEEHHHHCCCC
KGEINFADLGDNAKVILQHETEFALAKYLLQLGEVISTVEEDLSPNRLCEYLYELSKRFN
CCCEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AFYDRNQGVQVLSAEEPLRTSRLVLCDLTARTLKLGLSLLGIQVLERM
HHHCCCCCCEEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA