Click here to switch to the map view.

The map label for this gene is ureC [H]

Identifier: 17231162

GI number: 17231162

Start: 4424795

End: 4426501

Strand: Direct

Name: ureC [H]

Synonym: alr3670

Alternate gene names: 17231162

Gene position: 4424795-4426501 (Clockwise)

Preceding gene: 17231160

Following gene: 17231163

Centisome position: 68.99

GC content: 46.87

Gene sequence:

>1707_bases
ATGCCCTACAGAATGTCCCGCCAAGCCTACGCTGAAACCTACGGCCCCACAGTAGGCGATCGCATCCGACTTGCTGATAC
AGAATTATTTATACAAGTAGAGCAAGACTTCACAACCTACGGCGATGAGGTGAAATTCGGCGGTGGTAAAGTCATTAGAG
ATGGGATGGGACAATCTCCCATTGCTAACGCCGATGGTGCAGTAGATTTAGTCATTACGAATGCTTTAATCCTCGATTGG
TGGGGGATTGTCAAAGCAGATATCGGCATTAAAGATGGCAAAATATTTAAAATTGGGAAAGCCGGGAATCCCTATATTCA
AGATCATGTAGATATTATTATCGGCCCTGGAACCGAAGCCTTAGCGGGGGAAGGAATGATTCTCACGGCTGGCGGTATTG
ATACCCATATTCATTTTATTTGTCCCCAACAAATTGAAGTAGCGATCGCCTCCGGTATCACTACTATGATTGGCGGCGGT
ACAGGCCCAGCCACAGGAACCAACGCCACCACCTGCACCCCCGGCCCTTGGAATATGTACCGGATGCTGCAAGCGGCTGA
TGCGTTTCCTATGAACTTAGGATTTTTAGGTAAAGGTAACGCCAGTCAACCTCAAGGCTTAGTAGAACAAATTTTTGCGG
GTGCAATTGGTTTAAAGCTGCACGAAGATTGGGGAACCACACCCGCCACCATTGATACTTGCTTGACTGTAGCCGACGAA
TACGACGTACAAGTGGCCATTCACACCGACACCCTCAACGAAGCCGGATTTGTCGAAGATACCATCGCCGCTTTTAAAAA
TCGCGCCATCCATACTTACCACACCGAAGGCGCAGGCGGTGGACACGCACCAGATATTATCAAAGTCTGTGGACAAGCCA
ACGTTCTTCCATCTTCCACCAACCCTACCCGCCCTTACACCGTCAACACCTTAGACGAACACCTCGATATGTTGATGGTA
TGTCATCACCTTGATCCAGCGATCGCTGAAGATGTGGCTTTTGCTGAATCCCGCATCCGCCGCGAAACCATCGCCGCCGA
AGATATTCTCCATGATTTAGGCGCGTTTAGTATGATTGCTTCCGATTCCCAAGCTATGGGCAGAGTAGGGGAAGTAATAA
TTCGCACTTGGCAGACATCCCACAAAATGAAGGTGCAACGGGGAAGCCTTACCGGAGATGCTGAAGCAGACAATTTAAGA
GCTAAAAGATATGTTGCTAAATACACAATCAATCCGGCAATTACGCATGGAATCGCTCAGTATGTAGGTTCTGTAGAAGC
AGGTAAACTTGCAGATTTATGTTTGTGGCGACCAGCGTTTTTTGGTGTCAAACCAGAGATAGTCATTAAAGGCGGGATGA
TTGCTTGGTCACAAATGGGTGATGCTAACGCCAGCATTCCCACACCGCAACCTGTGCATATGCGTCCCATGTTTGGTAGT
TTTGCAGGTGCGAGAAATGCCACATCTTTAACCTTTGTTTCCCAAGCCGCTTTAGAAAGAGAAATTCCTCAGCAATTGGG
TTTACGAAAATCAGCAGTCGCAGTTTCTGGAACTCGCCAATTAACTAAACAGGATATGAAACTGAATGATGCCTTACCTC
ATATAGAAGTAGATTCAGAATCCTATGAAGTTAGAGCCGATGGGGAATTGTTGACTTGTGAACCTGCAACAGTGTTACCA
ATGGCGCAGAGGTATTTTTTATTTTAA

Upstream 100 bases:

>100_bases
ATTATCATCCCACTCAAATCATTCTCCTCCATTCTCCTCTATCCTTCGCGCTAACCTCCGCGCCCCTCCGCGTTTCAATC
TTAACCTCAAGGAATACACC

Downstream 100 bases:

>100_bases
CATTCGGATTAATTCCATCAAATTTTCAATTGCCAGATTGTTTATAGGGAGCTATCCTACTCTACGGAAGAGTCAAGCCT
GATATTTAGCTCAGTGCTTG

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha [H]

Number of amino acids: Translated: 568; Mature: 567

Protein sequence:

>568_residues
MPYRMSRQAYAETYGPTVGDRIRLADTELFIQVEQDFTTYGDEVKFGGGKVIRDGMGQSPIANADGAVDLVITNALILDW
WGIVKADIGIKDGKIFKIGKAGNPYIQDHVDIIIGPGTEALAGEGMILTAGGIDTHIHFICPQQIEVAIASGITTMIGGG
TGPATGTNATTCTPGPWNMYRMLQAADAFPMNLGFLGKGNASQPQGLVEQIFAGAIGLKLHEDWGTTPATIDTCLTVADE
YDVQVAIHTDTLNEAGFVEDTIAAFKNRAIHTYHTEGAGGGHAPDIIKVCGQANVLPSSTNPTRPYTVNTLDEHLDMLMV
CHHLDPAIAEDVAFAESRIRRETIAAEDILHDLGAFSMIASDSQAMGRVGEVIIRTWQTSHKMKVQRGSLTGDAEADNLR
AKRYVAKYTINPAITHGIAQYVGSVEAGKLADLCLWRPAFFGVKPEIVIKGGMIAWSQMGDANASIPTPQPVHMRPMFGS
FAGARNATSLTFVSQAALEREIPQQLGLRKSAVAVSGTRQLTKQDMKLNDALPHIEVDSESYEVRADGELLTCEPATVLP
MAQRYFLF

Sequences:

>Translated_568_residues
MPYRMSRQAYAETYGPTVGDRIRLADTELFIQVEQDFTTYGDEVKFGGGKVIRDGMGQSPIANADGAVDLVITNALILDW
WGIVKADIGIKDGKIFKIGKAGNPYIQDHVDIIIGPGTEALAGEGMILTAGGIDTHIHFICPQQIEVAIASGITTMIGGG
TGPATGTNATTCTPGPWNMYRMLQAADAFPMNLGFLGKGNASQPQGLVEQIFAGAIGLKLHEDWGTTPATIDTCLTVADE
YDVQVAIHTDTLNEAGFVEDTIAAFKNRAIHTYHTEGAGGGHAPDIIKVCGQANVLPSSTNPTRPYTVNTLDEHLDMLMV
CHHLDPAIAEDVAFAESRIRRETIAAEDILHDLGAFSMIASDSQAMGRVGEVIIRTWQTSHKMKVQRGSLTGDAEADNLR
AKRYVAKYTINPAITHGIAQYVGSVEAGKLADLCLWRPAFFGVKPEIVIKGGMIAWSQMGDANASIPTPQPVHMRPMFGS
FAGARNATSLTFVSQAALEREIPQQLGLRKSAVAVSGTRQLTKQDMKLNDALPHIEVDSESYEVRADGELLTCEPATVLP
MAQRYFLF
>Mature_567_residues
PYRMSRQAYAETYGPTVGDRIRLADTELFIQVEQDFTTYGDEVKFGGGKVIRDGMGQSPIANADGAVDLVITNALILDWW
GIVKADIGIKDGKIFKIGKAGNPYIQDHVDIIIGPGTEALAGEGMILTAGGIDTHIHFICPQQIEVAIASGITTMIGGGT
GPATGTNATTCTPGPWNMYRMLQAADAFPMNLGFLGKGNASQPQGLVEQIFAGAIGLKLHEDWGTTPATIDTCLTVADEY
DVQVAIHTDTLNEAGFVEDTIAAFKNRAIHTYHTEGAGGGHAPDIIKVCGQANVLPSSTNPTRPYTVNTLDEHLDMLMVC
HHLDPAIAEDVAFAESRIRRETIAAEDILHDLGAFSMIASDSQAMGRVGEVIIRTWQTSHKMKVQRGSLTGDAEADNLRA
KRYVAKYTINPAITHGIAQYVGSVEAGKLADLCLWRPAFFGVKPEIVIKGGMIAWSQMGDANASIPTPQPVHMRPMFGSF
AGARNATSLTFVSQAALEREIPQQLGLRKSAVAVSGTRQLTKQDMKLNDALPHIEVDSESYEVRADGELLTCEPATVLPM
AQRYFLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950 [H]

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha [H]

EC number: =3.5.1.5 [H]

Molecular weight: Translated: 61156; Mature: 61025

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS01120 UREASE_1 ; PS00145 UREASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYRMSRQAYAETYGPTVGDRIRLADTELFIQVEQDFTTYGDEVKFGGGKVIRDGMGQSP
CCCCCCHHHHHHHCCCCCCCEEEEECEEEEEEECCCCCCCCCEEEECCCEEEECCCCCCC
IANADGAVDLVITNALILDWWGIVKADIGIKDGKIFKIGKAGNPYIQDHVDIIIGPGTEA
CCCCCCCEEEEEHHHHHHHHHHHEEECCCCCCCCEEEECCCCCCCCCCCEEEEECCCCHH
LAGEGMILTAGGIDTHIHFICPQQIEVAIASGITTMIGGGTGPATGTNATTCTPGPWNMY
HCCCCEEEEECCCCEEEEEECCCHHHHHHHCCCHHEECCCCCCCCCCCCCCCCCCCHHHH
RMLQAADAFPMNLGFLGKGNASQPQGLVEQIFAGAIGLKLHEDWGTTPATIDTCLTVADE
HHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCEEEECCCCCCCHHHHHHHEECCC
YDVQVAIHTDTLNEAGFVEDTIAAFKNRAIHTYHTEGAGGGHAPDIIKVCGQANVLPSST
CEEEEEEEECCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHCCCCCCCCCCC
NPTRPYTVNTLDEHLDMLMVCHHLDPAIAEDVAFAESRIRRETIAAEDILHDLGAFSMIA
CCCCCEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDSQAMGRVGEVIIRTWQTSHKMKVQRGSLTGDAEADNLRAKRYVAKYTINPAITHGIAQ
CCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHEEEEEEECCHHHHHHHHH
YVGSVEAGKLADLCLWRPAFFGVKPEIVIKGGMIAWSQMGDANASIPTPQPVHMRPMFGS
HHCCCCCCCHHHHHHCCHHHCCCCCEEEEECCEEEEECCCCCCCCCCCCCCEEECCCHHH
FAGARNATSLTFVSQAALEREIPQQLGLRKSAVAVSGTRQLTKQDMKLNDALPHIEVDSE
HCCCCCCCEEHHHHHHHHHHHHHHHHCCCHHHEEECCHHHHHHHHHHHHCCCCCEEECCC
SYEVRADGELLTCEPATVLPMAQRYFLF
CEEEEECCCEEEECCCHHHHHHHHHHCC
>Mature Secondary Structure 
PYRMSRQAYAETYGPTVGDRIRLADTELFIQVEQDFTTYGDEVKFGGGKVIRDGMGQSP
CCCCCHHHHHHHCCCCCCCEEEEECEEEEEEECCCCCCCCCEEEECCCEEEECCCCCCC
IANADGAVDLVITNALILDWWGIVKADIGIKDGKIFKIGKAGNPYIQDHVDIIIGPGTEA
CCCCCCCEEEEEHHHHHHHHHHHEEECCCCCCCCEEEECCCCCCCCCCCEEEEECCCCHH
LAGEGMILTAGGIDTHIHFICPQQIEVAIASGITTMIGGGTGPATGTNATTCTPGPWNMY
HCCCCEEEEECCCCEEEEEECCCHHHHHHHCCCHHEECCCCCCCCCCCCCCCCCCCHHHH
RMLQAADAFPMNLGFLGKGNASQPQGLVEQIFAGAIGLKLHEDWGTTPATIDTCLTVADE
HHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCEEEECCCCCCCHHHHHHHEECCC
YDVQVAIHTDTLNEAGFVEDTIAAFKNRAIHTYHTEGAGGGHAPDIIKVCGQANVLPSST
CEEEEEEEECCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHCCCCCCCCCCC
NPTRPYTVNTLDEHLDMLMVCHHLDPAIAEDVAFAESRIRRETIAAEDILHDLGAFSMIA
CCCCCEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDSQAMGRVGEVIIRTWQTSHKMKVQRGSLTGDAEADNLRAKRYVAKYTINPAITHGIAQ
CCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHEEEEEEECCHHHHHHHHH
YVGSVEAGKLADLCLWRPAFFGVKPEIVIKGGMIAWSQMGDANASIPTPQPVHMRPMFGS
HHCCCCCCCHHHHHHCCHHHCCCCCEEEEECCEEEEECCCCCCCCCCCCCCEEECCCHHH
FAGARNATSLTFVSQAALEREIPQQLGLRKSAVAVSGTRQLTKQDMKLNDALPHIEVDSE
HCCCCCCCEEHHHHHHHHHHHHHHHHCCCHHHEEECCHHHHHHHHHHHHCCCCCEEECCC
SYEVRADGELLTCEPATVLPMAQRYFLF
CEEEEECCCEEEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA