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The map label for this gene is sasA [H]

Identifier: 17231092

GI number: 17231092

Start: 4349314

End: 4350519

Strand: Reverse

Name: sasA [H]

Synonym: all3600

Alternate gene names: 17231092

Gene position: 4350519-4349314 (Counterclockwise)

Preceding gene: 17231096

Following gene: 17231089

Centisome position: 67.83

GC content: 44.86

Gene sequence:

>1206_bases
GTGCTGAAACACGATTCCATGCAAGTTTCCCAGGATCAGCCTATTTATTCTGAGGCTCCACTCCAGCTGTTATTGTTCGT
CGATGGACGACCCAAGTCCAAACAGCAGGTGCAGCGTATCCGTGCTTACTTAAAAGACTTGCAGGCTGAGTATAACTTTG
AACTTCAAATCATTGATGTCGGGCAACAACCATACTTGGCAGAACATTTTAAGTTAGTAGCAACACCAGCTCTAATTAAA
ATTCATCCAGAACCCAGGCAGATTTTAGCCGGTAGTAACATCATCACCCAACTGAAAAATTTGTGGCCGCGCTGGCAAGC
AGCAGCAGATACCTATGCAAAGTTGCAAGAGGACTTGCAAGAACGTGTAGATGATAATGGCCGGGTGGCACAACCTCAAT
CAACTATCAATTCTGTCGCTGTTTCGGCAGAGCTGTTACGGCTTTCAGACGAAATATTCAATCTCAAACAAGAGAAAGAA
AAACTACTAGAGCAGTTACAGTTTAAAGACCGCGTAATTGCCATGTTAGTTCATGACCTCCGCAATCCCCTCACAGCAGC
AGCGATCGCTATCGAAACCCTACAATCTAACTACAACCCAGATATCGGCCAATTTCAACGCTTAAAACCCGCCTTAGTAG
TCAACCTATTAAGACAAGCCCGCACTCAAGCTAAAACAATTGATAAAATGATTGCGGATCTTTTACAAGTGGGTCGCGGT
ACTGATACCGAGCTAATTATTATACCACAAAAAACGGAAATAGGGTTACTCTGTTTAGAAGTACTAGGAGAATTGCGCGA
TCGCTATACCACCAAAGCGCAAAAAGTAGAAACAGACATTCCCCAAGATTTGCCCTGTGTCTATGCCGACCCCGAACGCA
TCCGCCAAGTACTGATAAATCTGCTAGATAATGCTATAAAATATACTCCAGAAGGCGGCACAATTAGTATTGCTGGACTA
CACCGTACTACCCAAAAAGTCCAATTTAGCATTGGCGATACCGGCCCCGGTATTCCCAGCGACAATCGAGAGCGTATATT
TGAAAACCACTATCGCTTAGAACGAGATGAAGCCAAAGAAGGCTACGGTATCGGTCTTTCTTTATGCCAACGCATAATAC
GCGCCCACTATGGTCAAATTTGGGTAGACTCCAACCCCCACGGTGGAGCGTGGTTCCACTTCACGTTACCCGTTTATCCA
TCTTAG

Upstream 100 bases:

>100_bases
GTAGTAAAAACCTAAAATAGATATTAAATTGAAAAAAGAACGACCATCGACACCTGTCAGTCTATTCTAATTTCCGCAAA
GCGTCGCCGGGTTGTTACCA

Downstream 100 bases:

>100_bases
AGATTGGGGATTGGCGACTGGGGACTGGTAGGGCGCAAGGGGAAAAGAAAACTATTGACTATCTTCCCATTGACAAATAC
GGTTCCGTCCTGATTCCTTA

Product: adaptive-response sensory kinase

Products: NA

Alternate protein names: Synechococcus adaptive sensor protein A [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MLKHDSMQVSQDQPIYSEAPLQLLLFVDGRPKSKQQVQRIRAYLKDLQAEYNFELQIIDVGQQPYLAEHFKLVATPALIK
IHPEPRQILAGSNIITQLKNLWPRWQAAADTYAKLQEDLQERVDDNGRVAQPQSTINSVAVSAELLRLSDEIFNLKQEKE
KLLEQLQFKDRVIAMLVHDLRNPLTAAAIAIETLQSNYNPDIGQFQRLKPALVVNLLRQARTQAKTIDKMIADLLQVGRG
TDTELIIIPQKTEIGLLCLEVLGELRDRYTTKAQKVETDIPQDLPCVYADPERIRQVLINLLDNAIKYTPEGGTISIAGL
HRTTQKVQFSIGDTGPGIPSDNRERIFENHYRLERDEAKEGYGIGLSLCQRIIRAHYGQIWVDSNPHGGAWFHFTLPVYP
S

Sequences:

>Translated_401_residues
MLKHDSMQVSQDQPIYSEAPLQLLLFVDGRPKSKQQVQRIRAYLKDLQAEYNFELQIIDVGQQPYLAEHFKLVATPALIK
IHPEPRQILAGSNIITQLKNLWPRWQAAADTYAKLQEDLQERVDDNGRVAQPQSTINSVAVSAELLRLSDEIFNLKQEKE
KLLEQLQFKDRVIAMLVHDLRNPLTAAAIAIETLQSNYNPDIGQFQRLKPALVVNLLRQARTQAKTIDKMIADLLQVGRG
TDTELIIIPQKTEIGLLCLEVLGELRDRYTTKAQKVETDIPQDLPCVYADPERIRQVLINLLDNAIKYTPEGGTISIAGL
HRTTQKVQFSIGDTGPGIPSDNRERIFENHYRLERDEAKEGYGIGLSLCQRIIRAHYGQIWVDSNPHGGAWFHFTLPVYP
S
>Mature_401_residues
MLKHDSMQVSQDQPIYSEAPLQLLLFVDGRPKSKQQVQRIRAYLKDLQAEYNFELQIIDVGQQPYLAEHFKLVATPALIK
IHPEPRQILAGSNIITQLKNLWPRWQAAADTYAKLQEDLQERVDDNGRVAQPQSTINSVAVSAELLRLSDEIFNLKQEKE
KLLEQLQFKDRVIAMLVHDLRNPLTAAAIAIETLQSNYNPDIGQFQRLKPALVVNLLRQARTQAKTIDKMIADLLQVGRG
TDTELIIIPQKTEIGLLCLEVLGELRDRYTTKAQKVETDIPQDLPCVYADPERIRQVLINLLDNAIKYTPEGGTISIAGL
HRTTQKVQFSIGDTGPGIPSDNRERIFENHYRLERDEAKEGYGIGLSLCQRIIRAHYGQIWVDSNPHGGAWFHFTLPVYP
S

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=257, Percent_Identity=29.5719844357977, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1786912, Length=262, Percent_Identity=29.3893129770992, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1788713, Length=254, Percent_Identity=24.8031496062992, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790861, Length=258, Percent_Identity=27.5193798449612, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788549, Length=237, Percent_Identity=28.6919831223629, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1786783, Length=229, Percent_Identity=31.0043668122271, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI145693157, Length=256, Percent_Identity=28.515625, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1789149, Length=257, Percent_Identity=27.6264591439689, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1790436, Length=244, Percent_Identity=26.2295081967213, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=25.1082251082251, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786600, Length=238, Percent_Identity=24.7899159663866, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87081816, Length=127, Percent_Identity=33.8582677165354, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI48994928, Length=113, Percent_Identity=31.858407079646, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787894, Length=112, Percent_Identity=35.7142857142857, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082128, Length=275, Percent_Identity=25.4545454545455, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 45566; Mature: 45566

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKHDSMQVSQDQPIYSEAPLQLLLFVDGRPKSKQQVQRIRAYLKDLQAEYNFELQIIDV
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEC
GQQPYLAEHFKLVATPALIKIHPEPRQILAGSNIITQLKNLWPRWQAAADTYAKLQEDLQ
CCCCHHHHHHHHHCCCEEEEECCCHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHH
ERVDDNGRVAQPQSTINSVAVSAELLRLSDEIFNLKQEKEKLLEQLQFKDRVIAMLVHDL
HHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNPLTAAAIAIETLQSNYNPDIGQFQRLKPALVVNLLRQARTQAKTIDKMIADLLQVGRG
HCHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TDTELIIIPQKTEIGLLCLEVLGELRDRYTTKAQKVETDIPQDLPCVYADPERIRQVLIN
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHH
LLDNAIKYTPEGGTISIAGLHRTTQKVQFSIGDTGPGIPSDNRERIFENHYRLERDEAKE
HHHHHHEECCCCCEEEEEECHHCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHCCC
GYGIGLSLCQRIIRAHYGQIWVDSNPHGGAWFHFTLPVYPS
CCCCCHHHHHHHHHHHCCEEEECCCCCCCEEEEEEECCCCC
>Mature Secondary Structure
MLKHDSMQVSQDQPIYSEAPLQLLLFVDGRPKSKQQVQRIRAYLKDLQAEYNFELQIIDV
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEC
GQQPYLAEHFKLVATPALIKIHPEPRQILAGSNIITQLKNLWPRWQAAADTYAKLQEDLQ
CCCCHHHHHHHHHCCCEEEEECCCHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHH
ERVDDNGRVAQPQSTINSVAVSAELLRLSDEIFNLKQEKEKLLEQLQFKDRVIAMLVHDL
HHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNPLTAAAIAIETLQSNYNPDIGQFQRLKPALVVNLLRQARTQAKTIDKMIADLLQVGRG
HCHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TDTELIIIPQKTEIGLLCLEVLGELRDRYTTKAQKVETDIPQDLPCVYADPERIRQVLIN
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHH
LLDNAIKYTPEGGTISIAGLHRTTQKVQFSIGDTGPGIPSDNRERIFENHYRLERDEAKE
HHHHHHEECCCCCEEEEEECHHCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHCCC
GYGIGLSLCQRIIRAHYGQIWVDSNPHGGAWFHFTLPVYPS
CCCCCHHHHHHHHHHHCCEEEECCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA