Click here to switch to the map view.

The map label for this gene is mnmG [H]

Identifier: 17231053

GI number: 17231053

Start: 4298709

End: 4300631

Strand: Direct

Name: mnmG [H]

Synonym: alr3561

Alternate gene names: 17231053

Gene position: 4298709-4300631 (Clockwise)

Preceding gene: 17231046

Following gene: 17231054

Centisome position: 67.02

GC content: 47.89

Gene sequence:

>1923_bases
ATGACCATGCACAATTCAGTGGAATTTCAAGACGCTTTTGATGTCATTGTCGTCGGTGCAGGTCACTCCGGTTGCGAAGC
AGCACTTGCTACTGCCCGCCTCGGCTGTCGTACCTTGTTACTGACGCTCAATTTGGATAAAATTGCTTGGCAACCTTGTA
ACCCTGCTGTGGGTGGGCCTGCCAAATCCCAGTTGACCCATGAGGTAGATGCCTTGGGTGGGGAAATTGGCAAGATGGCG
GATCGCACATATCTGCAAAAGCGCATCCTCAACTCTTCACGAGGGCCTGCGGTGTGGGCATTACGCGCCCAAACTGACAA
GCGGGAATATGCGGCTATTATGAAAAATATTGTTGAGAATCAAGAGAACTTGAGCATCCGCGAGAGTATGGTGACGGACT
TGGTACTGGGTGCTAACGATGAAGTGATAGGTGTGGAAACTTACTTTGGCGTGGCTTTCCAGTGTAAAGCTGTAATTTTA
ACCACAGGTACATTTCTGGGTGGGAAAATTTGGGTAGGGAACAAATCAATGCCAGCCGGACGTGCTGGGGAGTTTGCGGC
TGAGGGATTAACCGAAACCCTAAATCGTTTGGGATTTGAAACTGGTAGGTTGAAAACTGGTACACCCGCGCGGGTAGATA
AGCGGTCAGTAGATTACAGTAAGATGCAACTCCAGCCAGGGGATGCGGAAGTGCGTTGGTTTAGTTTTGACCCAGATGTG
TGGGTGGAACGGGAACAGCTACCTTGTCACATGACCCGCACCACCCCCGAAACCCATCGCCTGATTCGAGAAAACTTGCA
CCTATCGCCTGTGTATGGTGGTTGGGTAGAAGCCAAAGGCCCCCGTTATTGCCCCAGTATAGAAGACAAAATTGTCCGCT
TTGTTGATAAAGAAAGCCATCAAATCTTTATTGAACCAGAGGGACGGGATATTCCTGAATTATATATCCAAGGGTTTTCT
ACAGGGTTACCAGAAAATTTGCAACTACAGATGCTACGTAGTCTCCCTGGGTTGGAAAATTGCGTAATGTTACGTCCAGC
TTATGCTGTGGAATATGACTACTTACCCGCAACTCAGTGTTACCCCACACTGATGACAAAGAAGATTGCTGGCTTGTTTT
GTGCGGGACAGGTGAATGGTACAACCGGTTATGAAGAAGCCGCAGCCCAAGGCATTGTGGCCGGAATTAATGCGGCGCGG
TTTGTTCGAGATGAGGAAATGATAGTTTTCCCCCGTGAACACAGTTACTTAGGAACTTTAGTTGATGACCTGTGTACAAA
AGACCTCCGCGAACCTTACCGGATGCTGACCAGTCGTTCCGAATATCGCTTGCTGCTGCGTTCTGATAACGCTGACCAGC
GCCTAACTCCTTTAGGAAGGGAAATTGGCTTAATAGATGACCGTCGTTGGCAAATGTTTACCCGCAAACAAGAGCAGATT
ACAGGTGAGAAAGAACGCCTGTATGCTACCAGGGTAAAAGAAAATGATGACGTAGGCAAGGCGATCGCCTCTAATACCCA
ACAAGCCATCAAAGGTTCAATCACCTTGGCTGACTTGCTGCGTCGCCCTGGGTTCCATTACGTAGACCTCGATAGATATG
GGTTAGGAAACCCCGAACTTACCCCAGCCGAAAAAGAAGGGGCGGAAATTGACATCAAATACTCTGGTTATCTCGCCAGG
CAACAAAGCCAAATCGAACAAATTGCCCGTCAAGCACAGCGCCAATTACCAGGAGATTTAGATTACACAACTGTTGACAC
CCTCTCCAAAGAAGCGCGGGAAAAACTTAATAAAGTCAAACCCTTGACTATTGGTCAAGCAGCCCGAATTGGTGGAGTCA
ATCCAGCCGATATCAACGCCTTATTAATTTATTTAGAATTGCGTCAAAGCAAGCACCAGAAAGGATTAGCCGTTTTACCT
TAA

Upstream 100 bases:

>100_bases
TAACTCGATTTAGTTTTTTGTCAAAGGTTAGCCTACATGAAATCACTGGCTAGATTAGGTTAGAATCAGGAATAAATCTC
AGCTTGTTAATCCTGTACGT

Downstream 100 bases:

>100_bases
CTTCATCTTCATCAAGGGTGAGTATAGTAGAGGGAGGGATGGGTATGATAGATGACAAGAATCCAGAACTGACATCATCA
ACTGATCCCCGCTTTCGCGT

Product: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A [H]

Number of amino acids: Translated: 640; Mature: 639

Protein sequence:

>640_residues
MTMHNSVEFQDAFDVIVVGAGHSGCEAALATARLGCRTLLLTLNLDKIAWQPCNPAVGGPAKSQLTHEVDALGGEIGKMA
DRTYLQKRILNSSRGPAVWALRAQTDKREYAAIMKNIVENQENLSIRESMVTDLVLGANDEVIGVETYFGVAFQCKAVIL
TTGTFLGGKIWVGNKSMPAGRAGEFAAEGLTETLNRLGFETGRLKTGTPARVDKRSVDYSKMQLQPGDAEVRWFSFDPDV
WVEREQLPCHMTRTTPETHRLIRENLHLSPVYGGWVEAKGPRYCPSIEDKIVRFVDKESHQIFIEPEGRDIPELYIQGFS
TGLPENLQLQMLRSLPGLENCVMLRPAYAVEYDYLPATQCYPTLMTKKIAGLFCAGQVNGTTGYEEAAAQGIVAGINAAR
FVRDEEMIVFPREHSYLGTLVDDLCTKDLREPYRMLTSRSEYRLLLRSDNADQRLTPLGREIGLIDDRRWQMFTRKQEQI
TGEKERLYATRVKENDDVGKAIASNTQQAIKGSITLADLLRRPGFHYVDLDRYGLGNPELTPAEKEGAEIDIKYSGYLAR
QQSQIEQIARQAQRQLPGDLDYTTVDTLSKEAREKLNKVKPLTIGQAARIGGVNPADINALLIYLELRQSKHQKGLAVLP

Sequences:

>Translated_640_residues
MTMHNSVEFQDAFDVIVVGAGHSGCEAALATARLGCRTLLLTLNLDKIAWQPCNPAVGGPAKSQLTHEVDALGGEIGKMA
DRTYLQKRILNSSRGPAVWALRAQTDKREYAAIMKNIVENQENLSIRESMVTDLVLGANDEVIGVETYFGVAFQCKAVIL
TTGTFLGGKIWVGNKSMPAGRAGEFAAEGLTETLNRLGFETGRLKTGTPARVDKRSVDYSKMQLQPGDAEVRWFSFDPDV
WVEREQLPCHMTRTTPETHRLIRENLHLSPVYGGWVEAKGPRYCPSIEDKIVRFVDKESHQIFIEPEGRDIPELYIQGFS
TGLPENLQLQMLRSLPGLENCVMLRPAYAVEYDYLPATQCYPTLMTKKIAGLFCAGQVNGTTGYEEAAAQGIVAGINAAR
FVRDEEMIVFPREHSYLGTLVDDLCTKDLREPYRMLTSRSEYRLLLRSDNADQRLTPLGREIGLIDDRRWQMFTRKQEQI
TGEKERLYATRVKENDDVGKAIASNTQQAIKGSITLADLLRRPGFHYVDLDRYGLGNPELTPAEKEGAEIDIKYSGYLAR
QQSQIEQIARQAQRQLPGDLDYTTVDTLSKEAREKLNKVKPLTIGQAARIGGVNPADINALLIYLELRQSKHQKGLAVLP
>Mature_639_residues
TMHNSVEFQDAFDVIVVGAGHSGCEAALATARLGCRTLLLTLNLDKIAWQPCNPAVGGPAKSQLTHEVDALGGEIGKMAD
RTYLQKRILNSSRGPAVWALRAQTDKREYAAIMKNIVENQENLSIRESMVTDLVLGANDEVIGVETYFGVAFQCKAVILT
TGTFLGGKIWVGNKSMPAGRAGEFAAEGLTETLNRLGFETGRLKTGTPARVDKRSVDYSKMQLQPGDAEVRWFSFDPDVW
VEREQLPCHMTRTTPETHRLIRENLHLSPVYGGWVEAKGPRYCPSIEDKIVRFVDKESHQIFIEPEGRDIPELYIQGFST
GLPENLQLQMLRSLPGLENCVMLRPAYAVEYDYLPATQCYPTLMTKKIAGLFCAGQVNGTTGYEEAAAQGIVAGINAARF
VRDEEMIVFPREHSYLGTLVDDLCTKDLREPYRMLTSRSEYRLLLRSDNADQRLTPLGREIGLIDDRRWQMFTRKQEQIT
GEKERLYATRVKENDDVGKAIASNTQQAIKGSITLADLLRRPGFHYVDLDRYGLGNPELTPAEKEGAEIDIKYSGYLARQ
QSQIEQIARQAQRQLPGDLDYTTVDTLSKEAREKLNKVKPLTIGQAARIGGVNPADINALLIYLELRQSKHQKGLAVLP

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 [H]

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family [H]

Homologues:

Organism=Homo sapiens, GI74024895, Length=644, Percent_Identity=41.1490683229814, Blast_Score=430, Evalue=1e-120,
Organism=Homo sapiens, GI19882217, Length=669, Percent_Identity=39.6113602391629, Blast_Score=416, Evalue=1e-116,
Organism=Homo sapiens, GI183227703, Length=684, Percent_Identity=38.7426900584795, Blast_Score=410, Evalue=1e-114,
Organism=Escherichia coli, GI2367273, Length=619, Percent_Identity=49.2730210016155, Blast_Score=587, Evalue=1e-169,
Organism=Caenorhabditis elegans, GI17534255, Length=630, Percent_Identity=39.8412698412698, Blast_Score=438, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6321202, Length=646, Percent_Identity=42.2600619195046, Blast_Score=464, Evalue=1e-131,
Organism=Drosophila melanogaster, GI24658174, Length=636, Percent_Identity=41.9811320754717, Blast_Score=439, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595 [H]

Pfam domain/function: PF01134 GIDA [H]

EC number: NA

Molecular weight: Translated: 71426; Mature: 71295

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS01280 GIDA_1 ; PS01281 GIDA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMHNSVEFQDAFDVIVVGAGHSGCEAALATARLGCRTLLLTLNLDKIAWQPCNPAVGGP
CCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEEEEEEHHHHCCCCCCCCCCCC
AKSQLTHEVDALGGEIGKMADRTYLQKRILNSSRGPAVWALRAQTDKREYAAIMKNIVEN
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCC
QENLSIRESMVTDLVLGANDEVIGVETYFGVAFQCKAVILTTGTFLGGKIWVGNKSMPAG
CCCCHHHHHHHHHHHCCCCCCEEEEEHHHCEEEEEEEEEEEECCEECCEEEECCCCCCCC
RAGEFAAEGLTETLNRLGFETGRLKTGTPARVDKRSVDYSKMQLQPGDAEVRWFSFDPDV
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHEEECCCCCEEEEEECCCCC
WVEREQLPCHMTRTTPETHRLIRENLHLSPVYGGWVEAKGPRYCPSIEDKIVRFVDKESH
EEECCCCCEEEECCCHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHCCCCC
QIFIEPEGRDIPELYIQGFSTGLPENLQLQMLRSLPGLENCVMLRPAYAVEYDYLPATQC
EEEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEECCCCEEEECCCCCHHH
YPTLMTKKIAGLFCAGQVNGTTGYEEAAAQGIVAGINAARFVRDEEMIVFPREHSYLGTL
HHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHCCCHHHHCCCCCEEEECCCCCHHHHH
VDDLCTKDLREPYRMLTSRSEYRLLLRSDNADQRLTPLGREIGLIDDRRWQMFTRKQEQI
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
TGEKERLYATRVKENDDVGKAIASNTQQAIKGSITLADLLRRPGFHYVDLDRYGLGNPEL
CCCHHHEEHHHCCCCCCHHHHHHHCHHHHHHCCCHHHHHHHCCCCCEEECCCCCCCCCCC
TPAEKEGAEIDIKYSGYLARQQSQIEQIARQAQRQLPGDLDYTTVDTLSKEAREKLNKVK
CCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCC
PLTIGQAARIGGVNPADINALLIYLELRQSKHQKGLAVLP
CCCCCCHHHCCCCCCCCCEEEEEEEEHHHHHHCCCCCCCC
>Mature Secondary Structure 
TMHNSVEFQDAFDVIVVGAGHSGCEAALATARLGCRTLLLTLNLDKIAWQPCNPAVGGP
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEEEEEEHHHHCCCCCCCCCCCC
AKSQLTHEVDALGGEIGKMADRTYLQKRILNSSRGPAVWALRAQTDKREYAAIMKNIVEN
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCC
QENLSIRESMVTDLVLGANDEVIGVETYFGVAFQCKAVILTTGTFLGGKIWVGNKSMPAG
CCCCHHHHHHHHHHHCCCCCCEEEEEHHHCEEEEEEEEEEEECCEECCEEEECCCCCCCC
RAGEFAAEGLTETLNRLGFETGRLKTGTPARVDKRSVDYSKMQLQPGDAEVRWFSFDPDV
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHEEECCCCCEEEEEECCCCC
WVEREQLPCHMTRTTPETHRLIRENLHLSPVYGGWVEAKGPRYCPSIEDKIVRFVDKESH
EEECCCCCEEEECCCHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHCCCCC
QIFIEPEGRDIPELYIQGFSTGLPENLQLQMLRSLPGLENCVMLRPAYAVEYDYLPATQC
EEEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEECCCCEEEECCCCCHHH
YPTLMTKKIAGLFCAGQVNGTTGYEEAAAQGIVAGINAARFVRDEEMIVFPREHSYLGTL
HHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHCCCHHHHCCCCCEEEECCCCCHHHHH
VDDLCTKDLREPYRMLTSRSEYRLLLRSDNADQRLTPLGREIGLIDDRRWQMFTRKQEQI
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
TGEKERLYATRVKENDDVGKAIASNTQQAIKGSITLADLLRRPGFHYVDLDRYGLGNPEL
CCCHHHEEHHHCCCCCCHHHHHHHCHHHHHHCCCHHHHHHHCCCCCEEECCCCCCCCCCC
TPAEKEGAEIDIKYSGYLARQQSQIEQIARQAQRQLPGDLDYTTVDTLSKEAREKLNKVK
CCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCC
PLTIGQAARIGGVNPADINALLIYLELRQSKHQKGLAVLP
CCCCCCHHHCCCCCCCCCEEEEEEEEHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA