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The map label for this gene is ubiA [H]

Identifier: 17231045

GI number: 17231045

Start: 4282783

End: 4283655

Strand: Direct

Name: ubiA [H]

Synonym: alr3553

Alternate gene names: 17231045

Gene position: 4282783-4283655 (Clockwise)

Preceding gene: 17231040

Following gene: 17231046

Centisome position: 66.77

GC content: 45.02

Gene sequence:

>873_bases
ATGCTAGAAACTCACCAAGAACCCATTTGGCTGACAATTTTCCGTCTTTTGCGGTGGCACAAACCAGAAGGACGATTAAT
TTTGATGATTCCGGCACTTTGGGCTGTGTTTTTGGCGGCGGCTGGTAAACCCCCTTTGCCTTTGGTGGGGGTAATTGTTT
TGGGTACTCTAGCTACCAGTGCGGCTGGATGCGTGGTTAATGATTTGTGGGATCGGGATATTGATCCAGAAGTGGAGAGA
ACGCGCGATCGCCCTTTAGCAGCTCGGACTCTTTCTATAAAAGTTGGTATTGCAGTTGGTATTATAGCGTTATTTTGTGC
GGCAATTCTCGCCTATTACCTGAACTCCTTGAGCTTTTGGTTATCTGTGGCTGCTGTGCCTGTAATTTTGCTTTATCCGG
GTGCAAAGCGAGTGTTTCCTGTCCCGCAGTTGGTTTTGTCCATTGCTTGGGGTTTTGCGGTGTTAATTAGCTGGAGTGCA
GTAACACAAAACATTTCTCAAGCAACTTGGTTACTGTGGGGGGCAACCTTACTCTGGACATTGGGATTTGATACAGTTTA
CGCCATGAGCGATCGCGAAGATGATCAACGAATTGGGGTTAATTCCAGTGCCTTATTTTTTGGTGATTATGCTCCTTTAG
CTATTGGCATTTTCTTTTTAGGCACAATTATTTGCCTAACTTGGTTGGGTGTTGCCATCCACCTACATCTAGCATTCTGG
ATTACCTTAGGAATCGCTTCAGTTGGTTGGATTTGGCAGGTTTTACGTTTAAGACAGCCACAATTGCCCAATCCTGCTTA
TGGTGAGATGTTCCGGCAAAATGTCTGGATTGGTTTTATTGTACTGGCTGGGATGATATTCGGTTCTTTGTAA

Upstream 100 bases:

>100_bases
GAAACAGGATAGTCATAGGTAATCTACATCGATCCCCAATACCCAATACCCAATACCCAATACCCAATCCCCGATCCCCA
GTACCCGATCCCCAATCCCC

Downstream 100 bases:

>100_bases
GGAAGGGTATAGGGGTGTAAGGGTGTAAGGGGTTTAAAAATTGACATCCTCACTTACACCTTATACCAATCTCTTATTGC
GAAAATAACAGGGTAAAAGG

Product: 4-hydroxybenzoate polyprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MLETHQEPIWLTIFRLLRWHKPEGRLILMIPALWAVFLAAAGKPPLPLVGVIVLGTLATSAAGCVVNDLWDRDIDPEVER
TRDRPLAARTLSIKVGIAVGIIALFCAAILAYYLNSLSFWLSVAAVPVILLYPGAKRVFPVPQLVLSIAWGFAVLISWSA
VTQNISQATWLLWGATLLWTLGFDTVYAMSDREDDQRIGVNSSALFFGDYAPLAIGIFFLGTIICLTWLGVAIHLHLAFW
ITLGIASVGWIWQVLRLRQPQLPNPAYGEMFRQNVWIGFIVLAGMIFGSL

Sequences:

>Translated_290_residues
MLETHQEPIWLTIFRLLRWHKPEGRLILMIPALWAVFLAAAGKPPLPLVGVIVLGTLATSAAGCVVNDLWDRDIDPEVER
TRDRPLAARTLSIKVGIAVGIIALFCAAILAYYLNSLSFWLSVAAVPVILLYPGAKRVFPVPQLVLSIAWGFAVLISWSA
VTQNISQATWLLWGATLLWTLGFDTVYAMSDREDDQRIGVNSSALFFGDYAPLAIGIFFLGTIICLTWLGVAIHLHLAFW
ITLGIASVGWIWQVLRLRQPQLPNPAYGEMFRQNVWIGFIVLAGMIFGSL
>Mature_290_residues
MLETHQEPIWLTIFRLLRWHKPEGRLILMIPALWAVFLAAAGKPPLPLVGVIVLGTLATSAAGCVVNDLWDRDIDPEVER
TRDRPLAARTLSIKVGIAVGIIALFCAAILAYYLNSLSFWLSVAAVPVILLYPGAKRVFPVPQLVLSIAWGFAVLISWSA
VTQNISQATWLLWGATLLWTLGFDTVYAMSDREDDQRIGVNSSALFFGDYAPLAIGIFFLGTIICLTWLGVAIHLHLAFW
ITLGIASVGWIWQVLRLRQPQLPNPAYGEMFRQNVWIGFIVLAGMIFGSL

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=289, Percent_Identity=30.1038062283737, Blast_Score=121, Evalue=7e-28,
Organism=Escherichia coli, GI1790473, Length=275, Percent_Identity=33.8181818181818, Blast_Score=155, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17553718, Length=281, Percent_Identity=32.3843416370107, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI32565247, Length=281, Percent_Identity=32.0284697508897, Blast_Score=130, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17553720, Length=338, Percent_Identity=27.5147928994083, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI32565245, Length=135, Percent_Identity=35.5555555555556, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32565243, Length=135, Percent_Identity=35.5555555555556, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324370, Length=205, Percent_Identity=28.780487804878, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21355567, Length=280, Percent_Identity=32.5, Blast_Score=139, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 32122; Mature: 32122

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLETHQEPIWLTIFRLLRWHKPEGRLILMIPALWAVFLAAAGKPPLPLVGVIVLGTLATS
CCCCCCCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AAGCVVNDLWDRDIDPEVERTRDRPLAARTLSIKVGIAVGIIALFCAAILAYYLNSLSFW
HHHHHHHHHHCCCCCCHHHHHCCCCCHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
LSVAAVPVILLYPGAKRVFPVPQLVLSIAWGFAVLISWSAVTQNISQATWLLWGATLLWT
HHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGFDTVYAMSDREDDQRIGVNSSALFFGDYAPLAIGIFFLGTIICLTWLGVAIHLHLAFW
HCCHHEEEECCCCCCHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITLGIASVGWIWQVLRLRQPQLPNPAYGEMFRQNVWIGFIVLAGMIFGSL
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLETHQEPIWLTIFRLLRWHKPEGRLILMIPALWAVFLAAAGKPPLPLVGVIVLGTLATS
CCCCCCCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AAGCVVNDLWDRDIDPEVERTRDRPLAARTLSIKVGIAVGIIALFCAAILAYYLNSLSFW
HHHHHHHHHHCCCCCCHHHHHCCCCCHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
LSVAAVPVILLYPGAKRVFPVPQLVLSIAWGFAVLISWSAVTQNISQATWLLWGATLLWT
HHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGFDTVYAMSDREDDQRIGVNSSALFFGDYAPLAIGIFFLGTIICLTWLGVAIHLHLAFW
HCCHHEEEECCCCCCHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITLGIASVGWIWQVLRLRQPQLPNPAYGEMFRQNVWIGFIVLAGMIFGSL
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA