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The map label for this gene is 17231035

Identifier: 17231035

GI number: 17231035

Start: 4268608

End: 4270455

Strand: Direct

Name: 17231035

Synonym: alr3543

Alternate gene names: NA

Gene position: 4268608-4270455 (Clockwise)

Preceding gene: 17231031

Following gene: 17231036

Centisome position: 66.55

GC content: 45.29

Gene sequence:

>1848_bases
ATGAGAAGACTTATATTATTGTGCTTGTTTGTCATCGGGCTGGTATCTGCTGTATTTGGTTTCCTGAGTTTTCAGGGACT
AGCAGCTAAAGGCGAATTCGAGACAATTTTGTTAGATTTTCGAGAAGATATTCCAGCCGAGGTGATCAAACAGGATTTAC
AAGCGATCGCTCAACAATACAACGTTACACCCCAATTAGATAATAAATTCTCAGAACAAGATCATGTTTATATTATCAAA
GGCGATCGCCAGCGACTCAAAGCGTTGCAAAAATCTTCCTTTGCTAAAGCCACAGAAATTATTGAGCCGAATTATATCTA
TAGGCTAACTCCACCAGCCAAACCGGTTTGGTTGGGAGAAATCTTAGGAAGCGAACAAGGCCAAGAGTTTAACCCCTCCT
TAATTGGCCCCAACGATGAATATTACAGCAAACAGTGGAACCTCCACAAAATTGGTGTAGAAGGTGCATGGACTCAAACC
AAAGGTAGCGGCATAACTGTAGCCGTCATCGACACTGGTGTTACCCAAGTACGTGACTTAAAAGAAACCAAATTTGTTCA
AGGTTACGATTTCGTCAACGATAGAGTAGAAGCCACAGATGACAACGGACACGGTACTCACGTCGCCGGTACAGTCGCCC
AAGCTACCAACAATAAATATGGGGTAGCTGGAGTAGCTTACGAAGCCAGCCTCATGCCCTTAAAAGTCCTGAGTGCTTAC
GGTGGCGGAACCGTTGCTGATATTGCCGAAGCCATTAAATTTGCTGCTGACAAAGGCGCAGATGTCATTAATATGAGCTT
GGGTGGCGGTGGTGAAAGCCAATTACTCAAAGATGCTATCAACTATGCCCATAACAAAGGCGTAGTCATTATTGCGGCTG
CTGGTAATGAAAATGATAGTTCCGCCTCCTACCCCGCCCGTTATCCCCATGTGATTGGTGTTTCCGCCTTTGGCCCCGAT
GGCGAAAAAGCCCCCTATTCTAACTTTGGTGCTGGCGTTGATATTTCTGCCCCTGGTGGGAGTGACGCAGGTGCAATTCT
GCAAGAAACCATCAACGAACAAGGCGAAGGCGTGTTCCTGGGACTCCAAGGAACAAGCATGGCTGCACCCCACGTTGCTG
GTGTCGCTGCTTTAATTAAAGCTAGTGGCGTCAAAGAACCAGACGCAATTTTAGAAGTACTCAAACAATCGGCGCGGGTG
ATTCAAGACGATGGCTTAAACTACTACGGTGCTGGACAACTCAACGCCGAAGCCGCAGTTAAATTAGCCGCCCAAGGACA
AATCAGCTTCCAAGATTTCTTCCGTTGGTTGCGAGATAACGGCTATCTCAACCCCCGTTTCTGGTTTGATGGCGGTGCTG
TAGCACTATTGCCAAAAATATTAATGGTGGTTGGTTCCTATCTATTAGCTTGGTTTTTACGGGTCTACTTACCCTTCCCT
TGGAGTTGGTCTTTATCCAGTGGCTTGATTTTTGGTAGTTCTGGTCTATTCTTCCTCAAAGGAATCTATATATTCGACCT
ACCCCAATGGCCATTCCGAGTTTTGGGTAGTTCCATTCCCGAATTAGGTAACACCTTACAGGGAAGCAGTGCTTTAAACC
CCGTGTTTGCCAGTGTATTGATTCCGATTTTGTTAATAGCATTGCTATTAGGTCATCCCAGTTGGAAATGGTTTGCCATC
GGTTCAACTTTAGGCGTAGCGGCTTGTTTAACAGTCAGTGCGGTTTTAGACCCAGTAGTTTGGGGACTAAATGATGTGAA
CTTAGCGCGTATATTCCTAATTATCAACGCCTTACTTTGTTATGCACTCGCTCGTTTAGCATTGAAAAACGAAGAGAAAA
CAGCATAG

Upstream 100 bases:

>100_bases
TTAACTACAAACATTTAAGTAGATTACAAAGTACACCAATCAGGGACGCAGATAGGTTATCGTAGTGAGCAATAACTGGC
AAAAAGCGTGATGAGTTGAT

Downstream 100 bases:

>100_bases
AAAGGAGTGGGGTAAGAAAGTAGATAAGTATTACGCCCTCTTACCCTCCTCATTTCCCCTATTCCCAAATCCCCAACTTT
TATGAGTATTACAGTCACAG

Product: protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MRRLILLCLFVIGLVSAVFGFLSFQGLAAKGEFETILLDFREDIPAEVIKQDLQAIAQQYNVTPQLDNKFSEQDHVYIIK
GDRQRLKALQKSSFAKATEIIEPNYIYRLTPPAKPVWLGEILGSEQGQEFNPSLIGPNDEYYSKQWNLHKIGVEGAWTQT
KGSGITVAVIDTGVTQVRDLKETKFVQGYDFVNDRVEATDDNGHGTHVAGTVAQATNNKYGVAGVAYEASLMPLKVLSAY
GGGTVADIAEAIKFAADKGADVINMSLGGGGESQLLKDAINYAHNKGVVIIAAAGNENDSSASYPARYPHVIGVSAFGPD
GEKAPYSNFGAGVDISAPGGSDAGAILQETINEQGEGVFLGLQGTSMAAPHVAGVAALIKASGVKEPDAILEVLKQSARV
IQDDGLNYYGAGQLNAEAAVKLAAQGQISFQDFFRWLRDNGYLNPRFWFDGGAVALLPKILMVVGSYLLAWFLRVYLPFP
WSWSLSSGLIFGSSGLFFLKGIYIFDLPQWPFRVLGSSIPELGNTLQGSSALNPVFASVLIPILLIALLLGHPSWKWFAI
GSTLGVAACLTVSAVLDPVVWGLNDVNLARIFLIINALLCYALARLALKNEEKTA

Sequences:

>Translated_615_residues
MRRLILLCLFVIGLVSAVFGFLSFQGLAAKGEFETILLDFREDIPAEVIKQDLQAIAQQYNVTPQLDNKFSEQDHVYIIK
GDRQRLKALQKSSFAKATEIIEPNYIYRLTPPAKPVWLGEILGSEQGQEFNPSLIGPNDEYYSKQWNLHKIGVEGAWTQT
KGSGITVAVIDTGVTQVRDLKETKFVQGYDFVNDRVEATDDNGHGTHVAGTVAQATNNKYGVAGVAYEASLMPLKVLSAY
GGGTVADIAEAIKFAADKGADVINMSLGGGGESQLLKDAINYAHNKGVVIIAAAGNENDSSASYPARYPHVIGVSAFGPD
GEKAPYSNFGAGVDISAPGGSDAGAILQETINEQGEGVFLGLQGTSMAAPHVAGVAALIKASGVKEPDAILEVLKQSARV
IQDDGLNYYGAGQLNAEAAVKLAAQGQISFQDFFRWLRDNGYLNPRFWFDGGAVALLPKILMVVGSYLLAWFLRVYLPFP
WSWSLSSGLIFGSSGLFFLKGIYIFDLPQWPFRVLGSSIPELGNTLQGSSALNPVFASVLIPILLIALLLGHPSWKWFAI
GSTLGVAACLTVSAVLDPVVWGLNDVNLARIFLIINALLCYALARLALKNEEKTA
>Mature_615_residues
MRRLILLCLFVIGLVSAVFGFLSFQGLAAKGEFETILLDFREDIPAEVIKQDLQAIAQQYNVTPQLDNKFSEQDHVYIIK
GDRQRLKALQKSSFAKATEIIEPNYIYRLTPPAKPVWLGEILGSEQGQEFNPSLIGPNDEYYSKQWNLHKIGVEGAWTQT
KGSGITVAVIDTGVTQVRDLKETKFVQGYDFVNDRVEATDDNGHGTHVAGTVAQATNNKYGVAGVAYEASLMPLKVLSAY
GGGTVADIAEAIKFAADKGADVINMSLGGGGESQLLKDAINYAHNKGVVIIAAAGNENDSSASYPARYPHVIGVSAFGPD
GEKAPYSNFGAGVDISAPGGSDAGAILQETINEQGEGVFLGLQGTSMAAPHVAGVAALIKASGVKEPDAILEVLKQSARV
IQDDGLNYYGAGQLNAEAAVKLAAQGQISFQDFFRWLRDNGYLNPRFWFDGGAVALLPKILMVVGSYLLAWFLRVYLPFP
WSWSLSSGLIFGSSGLFFLKGIYIFDLPQWPFRVLGSSIPELGNTLQGSSALNPVFASVLIPILLIALLLGHPSWKWFAI
GSTLGVAACLTVSAVLDPVVWGLNDVNLARIFLIINALLCYALARLALKNEEKTA

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI27894285, Length=317, Percent_Identity=26.813880126183, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI20336190, Length=317, Percent_Identity=26.813880126183, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI20336188, Length=317, Percent_Identity=26.813880126183, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI20336180, Length=317, Percent_Identity=26.813880126183, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI4505577, Length=317, Percent_Identity=26.813880126183, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI20336186, Length=317, Percent_Identity=26.813880126183, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI20336182, Length=317, Percent_Identity=26.813880126183, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI20336184, Length=317, Percent_Identity=26.813880126183, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI31317307, Length=253, Percent_Identity=32.0158102766798, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320775, Length=234, Percent_Identity=37.6068376068376, Blast_Score=103, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6319893, Length=246, Percent_Identity=32.1138211382114, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6324576, Length=254, Percent_Identity=32.6771653543307, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI45550681, Length=410, Percent_Identity=24.6341463414634, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007280
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8; PF04151 PPC [H]

EC number: NA

Molecular weight: Translated: 66126; Mature: 66126

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLILLCLFVIGLVSAVFGFLSFQGLAAKGEFETILLDFREDIPAEVIKQDLQAIAQQY
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHCCCHHHHHHHHHHHHHHC
NVTPQLDNKFSEQDHVYIIKGDRQRLKALQKSSFAKATEIIEPNYIYRLTPPAKPVWLGE
CCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHH
ILGSEQGQEFNPSLIGPNDEYYSKQWNLHKIGVEGAWTQTKGSGITVAVIDTGVTQVRDL
HHCCCCCCCCCCCCCCCCHHHHCCCCCEEEECCCCCEEECCCCCEEEEEECCCHHHHHHH
KETKFVQGYDFVNDRVEATDDNGHGTHVAGTVAQATNNKYGVAGVAYEASLMPLKVLSAY
HHHHHHCCCHHHCCCEECCCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHC
GGGTVADIAEAIKFAADKGADVINMSLGGGGESQLLKDAINYAHNKGVVIIAAAGNENDS
CCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCC
SASYPARYPHVIGVSAFGPDGEKAPYSNFGAGVDISAPGGSDAGAILQETINEQGEGVFL
CCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCEEEE
GLQGTSMAAPHVAGVAALIKASGVKEPDAILEVLKQSARVIQDDGLNYYGAGQLNAEAAV
EECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHE
KLAAQGQISFQDFFRWLRDNGYLNPRFWFDGGAVALLPKILMVVGSYLLAWFLRVYLPFP
EEECCCCCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
WSWSLSSGLIFGSSGLFFLKGIYIFDLPQWPFRVLGSSIPELGNTLQGSSALNPVFASVL
CCCCCCCCEEECCCCCEECCCEEEEECCCCHHHHHCCHHHHHCCCCCCCCCCHHHHHHHH
IPILLIALLLGHPSWKWFAIGSTLGVAACLTVSAVLDPVVWGLNDVNLARIFLIINALLC
HHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
YALARLALKNEEKTA
HHHHHHHHCCCCCCC
>Mature Secondary Structure
MRRLILLCLFVIGLVSAVFGFLSFQGLAAKGEFETILLDFREDIPAEVIKQDLQAIAQQY
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHCCCHHHHHHHHHHHHHHC
NVTPQLDNKFSEQDHVYIIKGDRQRLKALQKSSFAKATEIIEPNYIYRLTPPAKPVWLGE
CCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHH
ILGSEQGQEFNPSLIGPNDEYYSKQWNLHKIGVEGAWTQTKGSGITVAVIDTGVTQVRDL
HHCCCCCCCCCCCCCCCCHHHHCCCCCEEEECCCCCEEECCCCCEEEEEECCCHHHHHHH
KETKFVQGYDFVNDRVEATDDNGHGTHVAGTVAQATNNKYGVAGVAYEASLMPLKVLSAY
HHHHHHCCCHHHCCCEECCCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHC
GGGTVADIAEAIKFAADKGADVINMSLGGGGESQLLKDAINYAHNKGVVIIAAAGNENDS
CCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCC
SASYPARYPHVIGVSAFGPDGEKAPYSNFGAGVDISAPGGSDAGAILQETINEQGEGVFL
CCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCEEEE
GLQGTSMAAPHVAGVAALIKASGVKEPDAILEVLKQSARVIQDDGLNYYGAGQLNAEAAV
EECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHE
KLAAQGQISFQDFFRWLRDNGYLNPRFWFDGGAVALLPKILMVVGSYLLAWFLRVYLPFP
EEECCCCCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
WSWSLSSGLIFGSSGLFFLKGIYIFDLPQWPFRVLGSSIPELGNTLQGSSALNPVFASVL
CCCCCCCCEEECCCCCEECCCEEEEECCCCHHHHHCCHHHHHCCCCCCCCCCHHHHHHHH
IPILLIALLLGHPSWKWFAIGSTLGVAACLTVSAVLDPVVWGLNDVNLARIFLIINALLC
HHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
YALARLALKNEEKTA
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2187155; 12024217 [H]