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The map label for this gene is argC

Identifier: 17231029

GI number: 17231029

Start: 4261776

End: 4262834

Strand: Direct

Name: argC

Synonym: alr3537

Alternate gene names: 17231029

Gene position: 4261776-4262834 (Clockwise)

Preceding gene: 17231027

Following gene: 17231031

Centisome position: 66.45

GC content: 46.18

Gene sequence:

>1059_bases
ATGGGCAATTTTGGACGCGTACCCGTTGGGATTGTTGGCGCGTCAGGCTATGGTGGGGTACAGTTAGTCCGATTACTGAT
GGATCATCCAGAAATCGAACTAGTTTATTTAGGTGGTGAGAGTAGTGTAGGTAAATCTTTTGCATCTCTCTACCCCCATT
TAGCTCATGCAGTTAAATTATCAATTGAAGAAGTAGACCCAGAAGTGATTGCGCGTCGCTGTGAAGTGGTGTTTCTCTCG
ATGCCAAATGGTCTGGCTTGTCAAATTGTGCCAACATTGTTGGAAAAAGGCTGTAAAGTACTGGATTTGAGTGCAGACTA
TCGATTCCGTAACTTGACAACTTACACCACTTGGTATGGTGTGGAAAGGAGCGATCGCACTACAGCCGACACCGCCATAT
ATGGTTTACCTGAACTTTACCGCGATCGCATCTCCGAAGCCCAATTAGTCGGCTGTCCTGGTTCCTACCCCACCGCTAGC
CTCTTAGCATTATCGCCACTGTTAAAACAAGGTTTAATCGTCCCCGAAACTGCTATTGTTGACGCTAAATCTGGTACATC
TGGCGGCGGGAGGGAAGCTAAAACTTATCTATTACTAGCAGAAGCAGATAATTCTCTCGCCCCTTATAGTGTCGTCCGTC
ACCGTCACACCCCAGAAATCGAGCAAATTTGTAGCGATTTGGCGGGTCACGAAGTTACAGTCCAATTTACGCCACATCTT
GTCCCTATAGTACGGGGAATTTTGGCAACTGTATACGCTACCCTGCGCGATCCTGGTTTAGTTGGAGATGATTTAACTAC
TATTTATACAGCCTTCTACCGTAATTCTCCCTGGGTAAAAGTTTGTGAAAGCGGCATTTATCCGCAAACAAAATGGGCTG
CGGGCAGCAATCTTTGTTATATCGGTGTAGAAGTTGACCCGCGTACTGGCCGGGTAATTGTCATGTCAGTAATTGACAAC
CTGATCAAAGGCCAAGCGGGTCAAGCAATTCAGTGTCTCAACATCATGATGGGTTGGGATGAGACATTGGGTTTACCAAA
AATGGGGTTTTATCCGTGA

Upstream 100 bases:

>100_bases
ACCACTAACGGAACTCAGTATACATAACTCATCACTCACCATAAGTTCTATAGTTAATAGCTGATCACAGATTAACCAAA
AACGGATAAGGATTTGAAAA

Downstream 100 bases:

>100_bases
TTGGGGATCGGGTATTGGGTATTGGGTATTTAGTATTGAGTAATGAAAGAGGATTTAATTTGTCCCCAGTCCCCAGTCCC
CAGTCCCCAGTCCCTAATCC

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR 1; N-acetyl-glutamate semialdehyde dehydrogenase 1; NAGSA dehydrogenase 1

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MGNFGRVPVGIVGASGYGGVQLVRLLMDHPEIELVYLGGESSVGKSFASLYPHLAHAVKLSIEEVDPEVIARRCEVVFLS
MPNGLACQIVPTLLEKGCKVLDLSADYRFRNLTTYTTWYGVERSDRTTADTAIYGLPELYRDRISEAQLVGCPGSYPTAS
LLALSPLLKQGLIVPETAIVDAKSGTSGGGREAKTYLLLAEADNSLAPYSVVRHRHTPEIEQICSDLAGHEVTVQFTPHL
VPIVRGILATVYATLRDPGLVGDDLTTIYTAFYRNSPWVKVCESGIYPQTKWAAGSNLCYIGVEVDPRTGRVIVMSVIDN
LIKGQAGQAIQCLNIMMGWDETLGLPKMGFYP

Sequences:

>Translated_352_residues
MGNFGRVPVGIVGASGYGGVQLVRLLMDHPEIELVYLGGESSVGKSFASLYPHLAHAVKLSIEEVDPEVIARRCEVVFLS
MPNGLACQIVPTLLEKGCKVLDLSADYRFRNLTTYTTWYGVERSDRTTADTAIYGLPELYRDRISEAQLVGCPGSYPTAS
LLALSPLLKQGLIVPETAIVDAKSGTSGGGREAKTYLLLAEADNSLAPYSVVRHRHTPEIEQICSDLAGHEVTVQFTPHL
VPIVRGILATVYATLRDPGLVGDDLTTIYTAFYRNSPWVKVCESGIYPQTKWAAGSNLCYIGVEVDPRTGRVIVMSVIDN
LIKGQAGQAIQCLNIMMGWDETLGLPKMGFYP
>Mature_351_residues
GNFGRVPVGIVGASGYGGVQLVRLLMDHPEIELVYLGGESSVGKSFASLYPHLAHAVKLSIEEVDPEVIARRCEVVFLSM
PNGLACQIVPTLLEKGCKVLDLSADYRFRNLTTYTTWYGVERSDRTTADTAIYGLPELYRDRISEAQLVGCPGSYPTASL
LALSPLLKQGLIVPETAIVDAKSGTSGGGREAKTYLLLAEADNSLAPYSVVRHRHTPEIEQICSDLAGHEVTVQFTPHLV
PIVRGILATVYATLRDPGLVGDDLTTIYTAFYRNSPWVKVCESGIYPQTKWAAGSNLCYIGVEVDPRTGRVIVMSVIDNL
IKGQAGQAIQCLNIMMGWDETLGLPKMGFYP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=341, Percent_Identity=35.4838709677419, Blast_Score=184, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6320913, Length=349, Percent_Identity=30.945558739255, Blast_Score=120, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC1_NOSS1 (Q8YRB1)

Other databases:

- EMBL:   BA000019
- PIR:   AB2248
- RefSeq:   NP_487577.1
- ProteinModelPortal:   Q8YRB1
- SMR:   Q8YRB1
- STRING:   Q8YRB1
- GeneID:   1107135
- GenomeReviews:   BA000019_GR
- KEGG:   ana:alr3537
- NMPDR:   fig|103690.1.peg.3844
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- PhylomeDB:   Q8YRB1
- ProtClustDB:   PRK00436
- BioCyc:   NSP103690:ALR3537-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 38240; Mature: 38108

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS01224 ARGC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNFGRVPVGIVGASGYGGVQLVRLLMDHPEIELVYLGGESSVGKSFASLYPHLAHAVKL
CCCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
SIEEVDPEVIARRCEVVFLSMPNGLACQIVPTLLEKGCKVLDLSADYRFRNLTTYTTWYG
HHHHCCHHHHHHEEEEEEEECCCCCEEHHHHHHHHCCCEEEEECCCCEECCEEEEEEEEE
VERSDRTTADTAIYGLPELYRDRISEAQLVGCPGSYPTASLLALSPLLKQGLIVPETAIV
CCCCCCCCHHHHHHCCHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEE
DAKSGTSGGGREAKTYLLLAEADNSLAPYSVVRHRHTPEIEQICSDLAGHEVTVQFTPHL
ECCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHCCCCCCHHHHHHHHCCCEEEEEECCCH
VPIVRGILATVYATLRDPGLVGDDLTTIYTAFYRNSPWVKVCESGIYPQTKWAAGSNLCY
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCEEE
IGVEVDPRTGRVIVMSVIDNLIKGQAGQAIQCLNIMMGWDETLGLPKMGFYP
EEEEECCCCCCEEEHHHHHHHHCCCCCCHHHHHHHHHCCHHHCCCCCCCCCC
>Mature Secondary Structure 
GNFGRVPVGIVGASGYGGVQLVRLLMDHPEIELVYLGGESSVGKSFASLYPHLAHAVKL
CCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
SIEEVDPEVIARRCEVVFLSMPNGLACQIVPTLLEKGCKVLDLSADYRFRNLTTYTTWYG
HHHHCCHHHHHHEEEEEEEECCCCCEEHHHHHHHHCCCEEEEECCCCEECCEEEEEEEEE
VERSDRTTADTAIYGLPELYRDRISEAQLVGCPGSYPTASLLALSPLLKQGLIVPETAIV
CCCCCCCCHHHHHHCCHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEE
DAKSGTSGGGREAKTYLLLAEADNSLAPYSVVRHRHTPEIEQICSDLAGHEVTVQFTPHL
ECCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHCCCCCCHHHHHHHHCCCEEEEEECCCH
VPIVRGILATVYATLRDPGLVGDDLTTIYTAFYRNSPWVKVCESGIYPQTKWAAGSNLCY
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCEEE
IGVEVDPRTGRVIVMSVIDNLIKGQAGQAIQCLNIMMGWDETLGLPKMGFYP
EEEEECCCCCCEEEHHHHHHHHCCCCCCHHHHHHHHHCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840