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The map label for this gene is pkn1 [H]

Identifier: 17230987

GI number: 17230987

Start: 4209923

End: 4210762

Strand: Direct

Name: pkn1 [H]

Synonym: alr3495

Alternate gene names: 17230987

Gene position: 4209923-4210762 (Clockwise)

Preceding gene: 17230986

Following gene: 17230988

Centisome position: 65.64

GC content: 47.62

Gene sequence:

>840_bases
ATGGCACAAACTATAATTGAACATCATCGACGGACAGGGCTGCATTTTGTTGAAGACTTGGGGAATGGAGTTCAACTAGA
GATGATGCTGATTAAAGGTGATATTTTTACGATGGGCGCACCAAAAACAGAGGAAGCCAGCAGAGATAGTGAACGACCTC
AACATGAAGTGACTATTCAAACTTTTTTTATGGGTAAGTATCAAGTCACTCAAGAGCAGTGGAAAGCAGTAGCAGTACTA
CCGCAGGTCAACAGAAAACTCAACCCAGACCCATCTAACTTTAAAGGTGCAAATCGACCTGTTGAGCAAGTATCTTGGTA
TGATGCGGTGGAGTTTTGCGATCGCCTGACTGCCCATACAAAAAGACCCTACCGCCTACCAACTGAAGCAGAATGGGAGT
ATGCGTGTAGAGCCGGAACAACAACCCCGTTTCATTTTGGCGAAACAATTACATCAGAGTTAGCTAACTATGATGCTACT
AAAACTTATGGTGCTGGGGTAAAAGGAACGTATCGACAAGAAACGACAGACGTAGGGAGCTTTGGCGTAGCGAATCATTT
TGGGCTATACGATATGCACGGAAACGTATGGGAATGGTGTCTAGACGATTGGCATAGTAGCTATGAAGGTGCGCCGACAG
ATGGTAGTGCGTGGTTTGATAATAATGATAACCTTTCTCAAAAGCAAGGACAAGCCGTGCTGCGGGGCGGCTCCTGGAGC
TCCTCTCCTGTAGTCTGCCGTTCCGCGTCCCGCGGCAACAACGATAGGGCGGGGCGCGTCTACCGCTACTACGCTGTTGG
TTTTCGTGTTGTCTGCGCGTTCGGGAGGACTTTTCAGTAG

Upstream 100 bases:

>100_bases
AGCCCTTTATACTTTTGTCCTTTTACCCTTTGTACTTGTTCTTTTTTACTTTTCTGTCGCCTTATGGCGACTCGAATTTT
TCACCAAAATATGAAGATTA

Downstream 100 bases:

>100_bases
CCCTTTATACTTTAGCTCTTTTCCACTTTGTACTTGTTCTTTTTTACTTTTTCTTAGCGTAACGGAGTGGAGCGTTGAAA
ATTTTTTTCAAATCAATCCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MAQTIIEHHRRTGLHFVEDLGNGVQLEMMLIKGDIFTMGAPKTEEASRDSERPQHEVTIQTFFMGKYQVTQEQWKAVAVL
PQVNRKLNPDPSNFKGANRPVEQVSWYDAVEFCDRLTAHTKRPYRLPTEAEWEYACRAGTTTPFHFGETITSELANYDAT
KTYGAGVKGTYRQETTDVGSFGVANHFGLYDMHGNVWEWCLDDWHSSYEGAPTDGSAWFDNNDNLSQKQGQAVLRGGSWS
SSPVVCRSASRGNNDRAGRVYRYYAVGFRVVCAFGRTFQ

Sequences:

>Translated_279_residues
MAQTIIEHHRRTGLHFVEDLGNGVQLEMMLIKGDIFTMGAPKTEEASRDSERPQHEVTIQTFFMGKYQVTQEQWKAVAVL
PQVNRKLNPDPSNFKGANRPVEQVSWYDAVEFCDRLTAHTKRPYRLPTEAEWEYACRAGTTTPFHFGETITSELANYDAT
KTYGAGVKGTYRQETTDVGSFGVANHFGLYDMHGNVWEWCLDDWHSSYEGAPTDGSAWFDNNDNLSQKQGQAVLRGGSWS
SSPVVCRSASRGNNDRAGRVYRYYAVGFRVVCAFGRTFQ
>Mature_278_residues
AQTIIEHHRRTGLHFVEDLGNGVQLEMMLIKGDIFTMGAPKTEEASRDSERPQHEVTIQTFFMGKYQVTQEQWKAVAVLP
QVNRKLNPDPSNFKGANRPVEQVSWYDAVEFCDRLTAHTKRPYRLPTEAEWEYACRAGTTTPFHFGETITSELANYDATK
TYGAGVKGTYRQETTDVGSFGVANHFGLYDMHGNVWEWCLDDWHSSYEGAPTDGSAWFDNNDNLSQKQGQAVLRGGSWSS
SPVVCRSASRGNNDRAGRVYRYYAVGFRVVCAFGRTFQ

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=212, Percent_Identity=32.0754716981132, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI194248087, Length=253, Percent_Identity=26.8774703557312, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI38202250, Length=237, Percent_Identity=29.1139240506329, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI257470977, Length=237, Percent_Identity=29.1139240506329, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI194248088, Length=268, Percent_Identity=26.1194029850746, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 31548; Mature: 31417

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQTIIEHHRRTGLHFVEDLGNGVQLEMMLIKGDIFTMGAPKTEEASRDSERPQHEVTIQ
CCCHHHHHHHHCCHHHHHHCCCCEEEEEEEEECCEEECCCCCCHHHCCCCCCCCCEEEEE
TFFMGKYQVTQEQWKAVAVLPQVNRKLNPDPSNFKGANRPVEQVSWYDAVEFCDRLTAHT
EEECCCEEECHHHHHEEEECHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
KRPYRLPTEAEWEYACRAGTTTPFHFGETITSELANYDATKTYGAGVKGTYRQETTDVGS
CCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
FGVANHFGLYDMHGNVWEWCLDDWHSSYEGAPTDGSAWFDNNDNLSQKQGQAVLRGGSWS
CCCHHCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCHHCCCEEEECCCCC
SSPVVCRSASRGNNDRAGRVYRYYAVGFRVVCAFGRTFQ
CCCEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AQTIIEHHRRTGLHFVEDLGNGVQLEMMLIKGDIFTMGAPKTEEASRDSERPQHEVTIQ
CCHHHHHHHHCCHHHHHHCCCCEEEEEEEEECCEEECCCCCCHHHCCCCCCCCCEEEEE
TFFMGKYQVTQEQWKAVAVLPQVNRKLNPDPSNFKGANRPVEQVSWYDAVEFCDRLTAHT
EEECCCEEECHHHHHEEEECHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
KRPYRLPTEAEWEYACRAGTTTPFHFGETITSELANYDATKTYGAGVKGTYRQETTDVGS
CCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
FGVANHFGLYDMHGNVWEWCLDDWHSSYEGAPTDGSAWFDNNDNLSQKQGQAVLRGGSWS
CCCHHCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCHHCCCEEEECCCCC
SSPVVCRSASRGNNDRAGRVYRYYAVGFRVVCAFGRTFQ
CCCEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]