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The map label for this gene is recQ [H]

Identifier: 17230943

GI number: 17230943

Start: 4160341

End: 4162437

Strand: Direct

Name: recQ [H]

Synonym: alr3451

Alternate gene names: 17230943

Gene position: 4160341-4162437 (Clockwise)

Preceding gene: 17230942

Following gene: 17230944

Centisome position: 64.87

GC content: 38.48

Gene sequence:

>2097_bases
ATGGTAACTCCAAATAAAGAAAAAGCATTATTACTGTTACGTCAGGCATTAGATAACCCAACATCTAATTTTCGTCCAGG
ACAGTGGGAAGCAATAGAAGAATTAATTGAAAGGCGATCACGTTTACTCGTCGTCCAACGTACTGGCTGGGGTAAAAGCT
TAGTTTATTTTTTAGCAACAAAACTATTGAGAGATAAAGGTGCTGGCTGTACCCTTTTAATTTCACCCCTACTAGCCTTG
ATGCGAAATCAAATTGCAGCCGCACAACGCATTGGAATCAAAGCTGCAACAATTAACTCTAGTAATCAAGATGAATGGCG
AGCCGTCAAAACACAATTATTAGCAGGACAAGTAGATATTTTACTGATTTCCCCTGAAAGACTAGCTAATAATGATTTTA
GGGAGAATATTCTCTTACCAATATCTCAAAGTATAGGCTTATTTGTAGTTGATGAAGCCCATTGTATTTCTGATTGGGGG
CATGACTTTCGCCCTGATTATCGGCGAATTGTGAGAATTTTACAAGGACTACCAAAAAATATTCCTATCCTCGCTACAAC
GGCTACTGCTAATAACCGAGTTATTGATGATATTATCGCTCAATTAGGTGCTAATTTGCAGGTTGTGAGAGGTAATTTAA
CTAGAGAAAGTCTGCGGTTGCAAAATATTTCCCTTCCCAGTCCAGCAGCAAGAATGGCTTGGTTAGTCGAACAATTACCT
CAACTACCTGGAAGCGGAATCATCTATACATTAACAGTGAGAGATGCTAATCGGGTTGCTAACTGGTTACAAACTCAAGG
CATTAATGCTAAGTCATACCATAGCGATTTAGAAAGTGATATTCGTATAACATTAGAAGACGAACTATTAAATAATCAAA
TTAAAGCTTTAGTAGCGACTACGGCTTTAGGTATGGGTTTTGATAAACCAGATTTAGGTTTTGTGATTCATTATCAACGC
CCTGGTTCGGTTGTCCACTATTATCAACAAGTAGGCAGAGCAGGTAGAGCAGTAGACATTGCTTATGGCATTCTTCTGAG
TGGTGATGAAGATGAGGAAATTACTAACTACTTTATTAATACAGCTTTTCCCCCACAAATTCATACTCAACAGGTTCTGA
ACATACTCAACCAAGAAGAAGGTCTTTCAGTACCACAATTAGAACAAAAATTAAATCTTTCTAGAGGACAAATCGACAAA
GTTTTAAAACTGTTATCATTGGAATCTCCTAGCCCAGTCACTAAAATAGATTCTAAATGGTATGTGACTGCTATTAACTA
TCAATATGATGAACAAAAAATTGCCAACTTAACAGCAATTCGCCGCCAAGAACAAGCCACAATGTCAGCATATATGCAGA
GTCAACAATGCTTAATGGCTTTTCTGGCAACCGAATTAGATGACGCAAATCCGCAAAATTGTGGTAAATGTGCTGTTTGC
GTAGGTAGACCTTTGCTACCAGTAAATTGTTCAATAGAAATGCTAAATCAAGCTGTTTTATATTTACGTCGCAGTCAACA
AATCATTGAACCGCGTAAACAATGGCCCTCACAAGCATTACTCAGTTATAAATTTTCTGGAAATATTAGCAATAATTTAA
GGGCGCAGGAAGGAAGGGCATTATCATTGTGGGGTGATGCTGGTTGGGGTGAATTAGTAAAACAAGGTAAATATAGAGAT
AATTATTTTAATGATGTATTGGTGCAAGGTACTGTAGAGATGATTAAACGTTGGCAACCACAACCGTTTCCTAGTTGGGT
GACTTGTGTGCCTTCATTAAATCGTCCAGAACTTGTACCAAACTTTGCTCAAAGGTTAGCTGAGAAGCTAGGTATAACTT
TTGTGCCAATTGTGCGTAAGGTTAAGCAAACACAGCTACAGAAAGATATGAGCAACAGTTACCAACAAGCTCATAATTTG
GATGGCGCATTTAAAATTGATGCTTGGCCAGGAATTGGTGGTTCTGTATTCTTAGTGGATGATATGGTAGATTCCCGTTG
GACTTTTACTGTAATTGCGGCGCTTTTACGCGGTGCTGGTAGTGGACAGGTTTTTCCTGTGGCATTAGCCCTCAATACAT
TAGGTCAAGGGGATTAG

Upstream 100 bases:

>100_bases
GCGTTAAAAAAATTGCCTAATTTATACAAATTATCATTCATTATTACTAATACTAGTCATTTTTGATGCTAAAACAAGAA
TAACTAATCACAGTGTATAT

Downstream 100 bases:

>100_bases
AAGACGATGTTAAATCATGTTTTGCCACCGGATACTCAAGCAATTTTGCTCTTGTGTGCTAGCTTTGGGCAAAGTCGCCA
AGTTGAACCACAACCCTTAA

Product: ATP-dependent DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 698; Mature: 698

Protein sequence:

>698_residues
MVTPNKEKALLLLRQALDNPTSNFRPGQWEAIEELIERRSRLLVVQRTGWGKSLVYFLATKLLRDKGAGCTLLISPLLAL
MRNQIAAAQRIGIKAATINSSNQDEWRAVKTQLLAGQVDILLISPERLANNDFRENILLPISQSIGLFVVDEAHCISDWG
HDFRPDYRRIVRILQGLPKNIPILATTATANNRVIDDIIAQLGANLQVVRGNLTRESLRLQNISLPSPAARMAWLVEQLP
QLPGSGIIYTLTVRDANRVANWLQTQGINAKSYHSDLESDIRITLEDELLNNQIKALVATTALGMGFDKPDLGFVIHYQR
PGSVVHYYQQVGRAGRAVDIAYGILLSGDEDEEITNYFINTAFPPQIHTQQVLNILNQEEGLSVPQLEQKLNLSRGQIDK
VLKLLSLESPSPVTKIDSKWYVTAINYQYDEQKIANLTAIRRQEQATMSAYMQSQQCLMAFLATELDDANPQNCGKCAVC
VGRPLLPVNCSIEMLNQAVLYLRRSQQIIEPRKQWPSQALLSYKFSGNISNNLRAQEGRALSLWGDAGWGELVKQGKYRD
NYFNDVLVQGTVEMIKRWQPQPFPSWVTCVPSLNRPELVPNFAQRLAEKLGITFVPIVRKVKQTQLQKDMSNSYQQAHNL
DGAFKIDAWPGIGGSVFLVDDMVDSRWTFTVIAALLRGAGSGQVFPVALALNTLGQGD

Sequences:

>Translated_698_residues
MVTPNKEKALLLLRQALDNPTSNFRPGQWEAIEELIERRSRLLVVQRTGWGKSLVYFLATKLLRDKGAGCTLLISPLLAL
MRNQIAAAQRIGIKAATINSSNQDEWRAVKTQLLAGQVDILLISPERLANNDFRENILLPISQSIGLFVVDEAHCISDWG
HDFRPDYRRIVRILQGLPKNIPILATTATANNRVIDDIIAQLGANLQVVRGNLTRESLRLQNISLPSPAARMAWLVEQLP
QLPGSGIIYTLTVRDANRVANWLQTQGINAKSYHSDLESDIRITLEDELLNNQIKALVATTALGMGFDKPDLGFVIHYQR
PGSVVHYYQQVGRAGRAVDIAYGILLSGDEDEEITNYFINTAFPPQIHTQQVLNILNQEEGLSVPQLEQKLNLSRGQIDK
VLKLLSLESPSPVTKIDSKWYVTAINYQYDEQKIANLTAIRRQEQATMSAYMQSQQCLMAFLATELDDANPQNCGKCAVC
VGRPLLPVNCSIEMLNQAVLYLRRSQQIIEPRKQWPSQALLSYKFSGNISNNLRAQEGRALSLWGDAGWGELVKQGKYRD
NYFNDVLVQGTVEMIKRWQPQPFPSWVTCVPSLNRPELVPNFAQRLAEKLGITFVPIVRKVKQTQLQKDMSNSYQQAHNL
DGAFKIDAWPGIGGSVFLVDDMVDSRWTFTVIAALLRGAGSGQVFPVALALNTLGQGD
>Mature_698_residues
MVTPNKEKALLLLRQALDNPTSNFRPGQWEAIEELIERRSRLLVVQRTGWGKSLVYFLATKLLRDKGAGCTLLISPLLAL
MRNQIAAAQRIGIKAATINSSNQDEWRAVKTQLLAGQVDILLISPERLANNDFRENILLPISQSIGLFVVDEAHCISDWG
HDFRPDYRRIVRILQGLPKNIPILATTATANNRVIDDIIAQLGANLQVVRGNLTRESLRLQNISLPSPAARMAWLVEQLP
QLPGSGIIYTLTVRDANRVANWLQTQGINAKSYHSDLESDIRITLEDELLNNQIKALVATTALGMGFDKPDLGFVIHYQR
PGSVVHYYQQVGRAGRAVDIAYGILLSGDEDEEITNYFINTAFPPQIHTQQVLNILNQEEGLSVPQLEQKLNLSRGQIDK
VLKLLSLESPSPVTKIDSKWYVTAINYQYDEQKIANLTAIRRQEQATMSAYMQSQQCLMAFLATELDDANPQNCGKCAVC
VGRPLLPVNCSIEMLNQAVLYLRRSQQIIEPRKQWPSQALLSYKFSGNISNNLRAQEGRALSLWGDAGWGELVKQGKYRD
NYFNDVLVQGTVEMIKRWQPQPFPSWVTCVPSLNRPELVPNFAQRLAEKLGITFVPIVRKVKQTQLQKDMSNSYQQAHNL
DGAFKIDAWPGIGGSVFLVDDMVDSRWTFTVIAALLRGAGSGQVFPVALALNTLGQGD

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=338, Percent_Identity=34.6153846153846, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI14591902, Length=337, Percent_Identity=34.4213649851632, Blast_Score=174, Evalue=3e-43,
Organism=Homo sapiens, GI14591904, Length=337, Percent_Identity=34.4213649851632, Blast_Score=174, Evalue=3e-43,
Organism=Homo sapiens, GI51242943, Length=353, Percent_Identity=32.0113314447592, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI51242947, Length=353, Percent_Identity=32.0113314447592, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI148612816, Length=353, Percent_Identity=32.0113314447592, Blast_Score=163, Evalue=5e-40,
Organism=Homo sapiens, GI110735439, Length=346, Percent_Identity=31.7919075144509, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI169218196, Length=346, Percent_Identity=32.0809248554913, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI284005309, Length=351, Percent_Identity=32.1937321937322, Blast_Score=146, Evalue=8e-35,
Organism=Homo sapiens, GI45446747, Length=327, Percent_Identity=23.5474006116208, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI45446743, Length=327, Percent_Identity=23.5474006116208, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI55749865, Length=334, Percent_Identity=26.0479041916168, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI48994977, Length=317, Percent_Identity=37.8548895899054, Blast_Score=203, Evalue=3e-53,
Organism=Escherichia coli, GI1787016, Length=327, Percent_Identity=25.3822629969419, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71987997, Length=323, Percent_Identity=34.984520123839, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI71987993, Length=323, Percent_Identity=34.984520123839, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI25145561, Length=355, Percent_Identity=31.5492957746479, Blast_Score=179, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI32564293, Length=326, Percent_Identity=33.4355828220859, Blast_Score=171, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17552866, Length=355, Percent_Identity=32.112676056338, Blast_Score=168, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17510307, Length=368, Percent_Identity=25.5434782608696, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71995514, Length=368, Percent_Identity=25.5434782608696, Blast_Score=66, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17510309, Length=368, Percent_Identity=25.5434782608696, Blast_Score=66, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=329, Percent_Identity=33.434650455927, Blast_Score=181, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6321360, Length=334, Percent_Identity=25.748502994012, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24646066, Length=335, Percent_Identity=34.9253731343284, Blast_Score=182, Evalue=6e-46,
Organism=Drosophila melanogaster, GI24664230, Length=329, Percent_Identity=33.434650455927, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI62472181, Length=329, Percent_Identity=33.434650455927, Blast_Score=151, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24664226, Length=329, Percent_Identity=33.434650455927, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI21358123, Length=344, Percent_Identity=32.8488372093023, Blast_Score=145, Evalue=8e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 78027; Mature: 78027

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS00690 DEAH_ATP_HELICASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTPNKEKALLLLRQALDNPTSNFRPGQWEAIEELIERRSRLLVVQRTGWGKSLVYFLAT
CCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHH
KLLRDKGAGCTLLISPLLALMRNQIAAAQRIGIKAATINSSNQDEWRAVKTQLLAGQVDI
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCEEE
LLISPERLANNDFRENILLPISQSIGLFVVDEAHCISDWGHDFRPDYRRIVRILQGLPKN
EEECCHHHCCCCCCCCEEEEECCCCCEEEEECCHHHHHCCCCCCHHHHHHHHHHHCCCCC
IPILATTATANNRVIDDIIAQLGANLQVVRGNLTRESLRLQNISLPSPAARMAWLVEQLP
CCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHH
QLPGSGIIYTLTVRDANRVANWLQTQGINAKSYHSDLESDIRITLEDELLNNQIKALVAT
CCCCCCEEEEEEECCHHHHHHHHHHCCCCCHHHHHCCCCCEEEEEHHHHHHHHHHHHHHH
TALGMGFDKPDLGFVIHYQRPGSVVHYYQQVGRAGRAVDIAYGILLSGDEDEEITNYFIN
HHHHCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCEEEEEEEEEECCCCCHHHHHHHHC
TAFPPQIHTQQVLNILNQEEGLSVPQLEQKLNLSRGQIDKVLKLLSLESPSPVTKIDSKW
CCCCCCCCHHHHHHHHCHHCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCE
YVTAINYQYDEQKIANLTAIRRQEQATMSAYMQSQQCLMAFLATELDDANPQNCGKCAVC
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHH
VGRPLLPVNCSIEMLNQAVLYLRRSQQIIEPRKQWPSQALLSYKFSGNISNNLRAQEGRA
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCCCCCCCE
LSLWGDAGWGELVKQGKYRDNYFNDVLVQGTVEMIKRWQPQPFPSWVTCVPSLNRPELVP
EEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHEECCCCCCCCCCH
NFAQRLAEKLGITFVPIVRKVKQTQLQKDMSNSYQQAHNLDGAFKIDAWPGIGGSVFLVD
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEE
DMVDSRWTFTVIAALLRGAGSGQVFPVALALNTLGQGD
CCCCCCHHHHHHHHHHHCCCCCCEEEHEEEHHHCCCCC
>Mature Secondary Structure
MVTPNKEKALLLLRQALDNPTSNFRPGQWEAIEELIERRSRLLVVQRTGWGKSLVYFLAT
CCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHH
KLLRDKGAGCTLLISPLLALMRNQIAAAQRIGIKAATINSSNQDEWRAVKTQLLAGQVDI
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCEEE
LLISPERLANNDFRENILLPISQSIGLFVVDEAHCISDWGHDFRPDYRRIVRILQGLPKN
EEECCHHHCCCCCCCCEEEEECCCCCEEEEECCHHHHHCCCCCCHHHHHHHHHHHCCCCC
IPILATTATANNRVIDDIIAQLGANLQVVRGNLTRESLRLQNISLPSPAARMAWLVEQLP
CCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHH
QLPGSGIIYTLTVRDANRVANWLQTQGINAKSYHSDLESDIRITLEDELLNNQIKALVAT
CCCCCCEEEEEEECCHHHHHHHHHHCCCCCHHHHHCCCCCEEEEEHHHHHHHHHHHHHHH
TALGMGFDKPDLGFVIHYQRPGSVVHYYQQVGRAGRAVDIAYGILLSGDEDEEITNYFIN
HHHHCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCEEEEEEEEEECCCCCHHHHHHHHC
TAFPPQIHTQQVLNILNQEEGLSVPQLEQKLNLSRGQIDKVLKLLSLESPSPVTKIDSKW
CCCCCCCCHHHHHHHHCHHCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCE
YVTAINYQYDEQKIANLTAIRRQEQATMSAYMQSQQCLMAFLATELDDANPQNCGKCAVC
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHH
VGRPLLPVNCSIEMLNQAVLYLRRSQQIIEPRKQWPSQALLSYKFSGNISNNLRAQEGRA
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCCCCCCCE
LSLWGDAGWGELVKQGKYRDNYFNDVLVQGTVEMIKRWQPQPFPSWVTCVPSLNRPELVP
EEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHEECCCCCCCCCCH
NFAQRLAEKLGITFVPIVRKVKQTQLQKDMSNSYQQAHNLDGAFKIDAWPGIGGSVFLVD
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEE
DMVDSRWTFTVIAALLRGAGSGQVFPVALALNTLGQGD
CCCCCCHHHHHHHHHHHCCCCCCEEEHEEEHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]