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The map label for this gene is pab [H]

Identifier: 17230935

GI number: 17230935

Start: 4151646

End: 4153790

Strand: Direct

Name: pab [H]

Synonym: alr3443

Alternate gene names: 17230935

Gene position: 4151646-4153790 (Clockwise)

Preceding gene: 17230934

Following gene: 17230936

Centisome position: 64.73

GC content: 43.59

Gene sequence:

>2145_bases
ATGGCCGATATCAAAACATTAATTATTGACAACTACGACTCTTATACTTTTAATCTCTACCAGATGATTGCTGAAGTCAA
CGGAGAGTTGCCCCTTGTTATTCATAATGACAAATTAGATTGGTATGAATTAAAACAACTTGTTTTTGATAATATAGTCA
TTTCTCCTGGGCCTGGTCGTCCTGAAAACCCTAAAGATTTCGGTATTTGTCAACAGATACTACAAAACTATTTAGATGTT
CCCTTGCTTGGTGTTTGTCTTGGTCACCAAGGAATTGGTCATTATTATGGTGGTAAGGTCATCCACGCACCAGAACCTAA
ACATGGTCGATTGAGTCATGTTTATCATAATGGTGGTGATTTATTCCAAGAAATTCCTACACCTTTTCAAGTTGTCCGCT
ATCATTCTTTGCTGGTTGCGGAAGAATTGCCCAGTTGTTTAGAAAAAGTAGCCTGGACTGAAGACGGGTTGGTAATGGGG
TTGCGTCATCGTCATTTGCCATTGTGGGGGGTGCAGTTTCACCCAGAATCTATCTGTAGTGAGTATGGATATAAATTGCT
GGAAAACTTCCAAGCCATTACGGAAGGATTCATCCGCCAAAATGGTAGACATCGCCCCAAATTAGAAAGCAAAAGTTTCT
CTATTTCTCCTAACTCACCTATTCCAGCGCCATCCCAAGAATTTACTGTTTGTAGCCAAAAACTAGATTATTACCTTGAT
ACAGAACAGACATTTGTTCATCTTTTTGGTGAAGATCCTCATGCTTTTTGGCTTGATAGTAGCCTTGTAGAACCAGGATT
ATCCCGTTTCTCTTTTATGGGAGGAAGCGGGGGGATAAACAGTTTACTCGTTTCTTACTGCACCCAATCTCAAGAATTGA
CGATTACACAATCGGGTAAGGTGACACGCACTCAAGAGAGTATTTTTGACTATCTCAAACGCGAAATTAATCGTCGCCGT
TGCCCATCTGATGAGCTACCTTTTGATTTTAACTGTGGTTTTGTGGGCTACTTTGGTTATGAACTGAAGGCAAAATCCGG
GTCTGGGTTAGAGCATCCCTCATTATTTCCCGATGCTATCTTGATTTTAAGCGATCGCCTGATTGCTTTTGACCACCAAG
AGCAAACCACTTACTTAGTTTACCTCGCCCCTGTGGGTGAAACAGCACCAGCCCAAGCCTGGTTTGAACTAACTGAAAAA
CGTCTGCGGACACTCCCGCCTCTTCCTCCCCTCGTTCCTAGTACTACATCTCACCCCGTTACTTTCCGTTTAAGTCGGTC
ATACCAGACATATAAAGATGATATTTCTAGATGTCTCAAAGAAATTCGTGAGGGGGAAACTTACCAAGTTTGCCTGACTA
ATCGATTATGCACAGACACAATTGCTGATCCATTGGAATTTTATCGCCGATTACGCCAAGTTAATCCGGCTCCCTACTCT
GCTTTTCTACGGTTTGGTGAGATGGCGATCGCCTGTTCTTCCCCGGAGCGATTTCTGCAAATTGACCGTCAAGGCTGGGT
AGAAACCAAGCCGATCAAGGGAACTGTACGCCGGGGAGAGACTCCCGAAGAAGATTTTTTACTCCGGGAAAGTTTGCGTA
GCAGCGAAAAAGAGCGATCCGAAAACTTAATGATTGTTGATTTATTACGCAACGATTTAGGGCGAGTTTGCCAAGTCGGG
AGTATCCATGTTCCCAAATTAATGGATGTAGAAAGTTATGCAACGGTGCATCAACTTGTCAGCACTATCCGTGGTTTATT
ATCCCCCGACATGGACGCAACCGACTGCATTCGTCTGGCATTTCCGGGCGGCTCGATGACAGGTGCGCCTAAACTGAGAA
CGATGGAGATTATTGATCAACTTGAGCAAGAGGCGCGGGGAGTTTATTCAGGGGCGATCGGTTTTTTGGGTGTAAACGGT
ACAGCCGACTTGAATATTGTCATCCGTACCGCCGTACTGACACCAAATCAAACTTCTATTGGTATAGGGGGTGGGATTGT
CGCACTCTCTGATGTGGAAATGGAATTTCAAGAAACTATCCTCAAAGCTAATGCGCTAATTCAGGCGATGCTCTTGACTG
TTCACGGAGAATATCATCCTAGTCTTTACCGTATTTTAGGAATGCCCACAGAGGTTTTCTGTTGA

Upstream 100 bases:

>100_bases
ATCCAAGCCCGTAGATCCAGATGCTTTAATTGAGGCGATCGGTAATTTGGTCAATAATCAATAAGTGCATGAGTGCAACT
TCTGGTTATCTATTATTCCA

Downstream 100 bases:

>100_bases
GACTAGATATAAGGGTTTTCACTGATTTAAATTTCCAGACTTGCTGCTAAATTTCTTTGAGGTTTCCCTATGCCAATTTA
CGTTTACTGGGGCGAAGATG

Product: p-aminobenzoic acid synthase

Products: NA

Alternate protein names: P-aminobenzoic acid synthase; PABA synthase [H]

Number of amino acids: Translated: 714; Mature: 713

Protein sequence:

>714_residues
MADIKTLIIDNYDSYTFNLYQMIAEVNGELPLVIHNDKLDWYELKQLVFDNIVISPGPGRPENPKDFGICQQILQNYLDV
PLLGVCLGHQGIGHYYGGKVIHAPEPKHGRLSHVYHNGGDLFQEIPTPFQVVRYHSLLVAEELPSCLEKVAWTEDGLVMG
LRHRHLPLWGVQFHPESICSEYGYKLLENFQAITEGFIRQNGRHRPKLESKSFSISPNSPIPAPSQEFTVCSQKLDYYLD
TEQTFVHLFGEDPHAFWLDSSLVEPGLSRFSFMGGSGGINSLLVSYCTQSQELTITQSGKVTRTQESIFDYLKREINRRR
CPSDELPFDFNCGFVGYFGYELKAKSGSGLEHPSLFPDAILILSDRLIAFDHQEQTTYLVYLAPVGETAPAQAWFELTEK
RLRTLPPLPPLVPSTTSHPVTFRLSRSYQTYKDDISRCLKEIREGETYQVCLTNRLCTDTIADPLEFYRRLRQVNPAPYS
AFLRFGEMAIACSSPERFLQIDRQGWVETKPIKGTVRRGETPEEDFLLRESLRSSEKERSENLMIVDLLRNDLGRVCQVG
SIHVPKLMDVESYATVHQLVSTIRGLLSPDMDATDCIRLAFPGGSMTGAPKLRTMEIIDQLEQEARGVYSGAIGFLGVNG
TADLNIVIRTAVLTPNQTSIGIGGGIVALSDVEMEFQETILKANALIQAMLLTVHGEYHPSLYRILGMPTEVFC

Sequences:

>Translated_714_residues
MADIKTLIIDNYDSYTFNLYQMIAEVNGELPLVIHNDKLDWYELKQLVFDNIVISPGPGRPENPKDFGICQQILQNYLDV
PLLGVCLGHQGIGHYYGGKVIHAPEPKHGRLSHVYHNGGDLFQEIPTPFQVVRYHSLLVAEELPSCLEKVAWTEDGLVMG
LRHRHLPLWGVQFHPESICSEYGYKLLENFQAITEGFIRQNGRHRPKLESKSFSISPNSPIPAPSQEFTVCSQKLDYYLD
TEQTFVHLFGEDPHAFWLDSSLVEPGLSRFSFMGGSGGINSLLVSYCTQSQELTITQSGKVTRTQESIFDYLKREINRRR
CPSDELPFDFNCGFVGYFGYELKAKSGSGLEHPSLFPDAILILSDRLIAFDHQEQTTYLVYLAPVGETAPAQAWFELTEK
RLRTLPPLPPLVPSTTSHPVTFRLSRSYQTYKDDISRCLKEIREGETYQVCLTNRLCTDTIADPLEFYRRLRQVNPAPYS
AFLRFGEMAIACSSPERFLQIDRQGWVETKPIKGTVRRGETPEEDFLLRESLRSSEKERSENLMIVDLLRNDLGRVCQVG
SIHVPKLMDVESYATVHQLVSTIRGLLSPDMDATDCIRLAFPGGSMTGAPKLRTMEIIDQLEQEARGVYSGAIGFLGVNG
TADLNIVIRTAVLTPNQTSIGIGGGIVALSDVEMEFQETILKANALIQAMLLTVHGEYHPSLYRILGMPTEVFC
>Mature_713_residues
ADIKTLIIDNYDSYTFNLYQMIAEVNGELPLVIHNDKLDWYELKQLVFDNIVISPGPGRPENPKDFGICQQILQNYLDVP
LLGVCLGHQGIGHYYGGKVIHAPEPKHGRLSHVYHNGGDLFQEIPTPFQVVRYHSLLVAEELPSCLEKVAWTEDGLVMGL
RHRHLPLWGVQFHPESICSEYGYKLLENFQAITEGFIRQNGRHRPKLESKSFSISPNSPIPAPSQEFTVCSQKLDYYLDT
EQTFVHLFGEDPHAFWLDSSLVEPGLSRFSFMGGSGGINSLLVSYCTQSQELTITQSGKVTRTQESIFDYLKREINRRRC
PSDELPFDFNCGFVGYFGYELKAKSGSGLEHPSLFPDAILILSDRLIAFDHQEQTTYLVYLAPVGETAPAQAWFELTEKR
LRTLPPLPPLVPSTTSHPVTFRLSRSYQTYKDDISRCLKEIREGETYQVCLTNRLCTDTIADPLEFYRRLRQVNPAPYSA
FLRFGEMAIACSSPERFLQIDRQGWVETKPIKGTVRRGETPEEDFLLRESLRSSEKERSENLMIVDLLRNDLGRVCQVGS
IHVPKLMDVESYATVHQLVSTIRGLLSPDMDATDCIRLAFPGGSMTGAPKLRTMEIIDQLEQEARGVYSGAIGFLGVNGT
ADLNIVIRTAVLTPNQTSIGIGGGIVALSDVEMEFQETILKANALIQAMLLTVHGEYHPSLYRILGMPTEVFC

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=444, Percent_Identity=35.8108108108108, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI1787518, Length=401, Percent_Identity=31.9201995012469, Blast_Score=175, Evalue=1e-44,
Organism=Escherichia coli, GI1789760, Length=186, Percent_Identity=46.7741935483871, Blast_Score=168, Evalue=1e-42,
Organism=Escherichia coli, GI1787517, Length=213, Percent_Identity=35.6807511737089, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1786809, Length=264, Percent_Identity=25, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082077, Length=257, Percent_Identity=26.4591439688716, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6324361, Length=791, Percent_Identity=29.0771175726928, Blast_Score=246, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6320935, Length=446, Percent_Identity=33.1838565022422, Blast_Score=211, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6322638, Length=198, Percent_Identity=37.8787878787879, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR006805
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR015890
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR005802
- InterPro:   IPR006221 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind; PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 80401; Mature: 80270

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADIKTLIIDNYDSYTFNLYQMIAEVNGELPLVIHNDKLDWYELKQLVFDNIVISPGPGR
CCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCEEECCCCCC
PENPKDFGICQQILQNYLDVPLLGVCLGHQGIGHYYGGKVIHAPEPKHGRLSHVYHNGGD
CCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHCCCEEEECCCCCCCCEEEEEECCCH
LFQEIPTPFQVVRYHSLLVAEELPSCLEKVAWTEDGLVMGLRHRHLPLWGVQFHPESICS
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCCCCEEEEEECHHHHHH
EYGYKLLENFQAITEGFIRQNGRHRPKLESKSFSISPNSPIPAPSQEFTVCSQKLDYYLD
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHCEEEC
TEQTFVHLFGEDPHAFWLDSSLVEPGLSRFSFMGGSGGINSLLVSYCTQSQELTITQSGK
CCCEEEEEECCCCCEEEECCHHHHCCHHHHEECCCCCCHHHHHHHHHCCCCCEEEECCCC
VTRTQESIFDYLKREINRRRCPSDELPFDFNCGFVGYFGYELKAKSGSGLEHPSLFPDAI
CCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEEECEEEEECCCCCCCCCCCCHHHH
LILSDRLIAFDHQEQTTYLVYLAPVGETAPAQAWFELTEKRLRTLPPLPPLVPSTTSHPV
HHHHCCEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCE
TFRLSRSYQTYKDDISRCLKEIREGETYQVCLTNRLCTDTIADPLEFYRRLRQVNPAPYS
EEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHH
AFLRFGEMAIACSSPERFLQIDRQGWVETKPIKGTVRRGETPEEDFLLRESLRSSEKERS
HHHHHCCEEEEECCCHHHHHHHCCCCEECCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHH
ENLMIVDLLRNDLGRVCQVGSIHVPKLMDVESYATVHQLVSTIRGLLSPDMDATDCIRLA
CCEEEHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
FPGGSMTGAPKLRTMEIIDQLEQEARGVYSGAIGFLGVNGTADLNIVIRTAVLTPNQTSI
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEEEEEECCCCCCC
GIGGGIVALSDVEMEFQETILKANALIQAMLLTVHGEYHPSLYRILGMPTEVFC
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHCC
>Mature Secondary Structure 
ADIKTLIIDNYDSYTFNLYQMIAEVNGELPLVIHNDKLDWYELKQLVFDNIVISPGPGR
CCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCEEECCCCCC
PENPKDFGICQQILQNYLDVPLLGVCLGHQGIGHYYGGKVIHAPEPKHGRLSHVYHNGGD
CCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHCCCEEEECCCCCCCCEEEEEECCCH
LFQEIPTPFQVVRYHSLLVAEELPSCLEKVAWTEDGLVMGLRHRHLPLWGVQFHPESICS
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCCCCEEEEEECHHHHHH
EYGYKLLENFQAITEGFIRQNGRHRPKLESKSFSISPNSPIPAPSQEFTVCSQKLDYYLD
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHCEEEC
TEQTFVHLFGEDPHAFWLDSSLVEPGLSRFSFMGGSGGINSLLVSYCTQSQELTITQSGK
CCCEEEEEECCCCCEEEECCHHHHCCHHHHEECCCCCCHHHHHHHHHCCCCCEEEECCCC
VTRTQESIFDYLKREINRRRCPSDELPFDFNCGFVGYFGYELKAKSGSGLEHPSLFPDAI
CCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEEECEEEEECCCCCCCCCCCCHHHH
LILSDRLIAFDHQEQTTYLVYLAPVGETAPAQAWFELTEKRLRTLPPLPPLVPSTTSHPV
HHHHCCEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCE
TFRLSRSYQTYKDDISRCLKEIREGETYQVCLTNRLCTDTIADPLEFYRRLRQVNPAPYS
EEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHH
AFLRFGEMAIACSSPERFLQIDRQGWVETKPIKGTVRRGETPEEDFLLRESLRSSEKERS
HHHHHCCEEEEECCCHHHHHHHCCCCEECCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHH
ENLMIVDLLRNDLGRVCQVGSIHVPKLMDVESYATVHQLVSTIRGLLSPDMDATDCIRLA
CCEEEHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
FPGGSMTGAPKLRTMEIIDQLEQEARGVYSGAIGFLGVNGTADLNIVIRTAVLTPNQTSI
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEEEEEECCCCCCC
GIGGGIVALSDVEMEFQETILKANALIQAMLLTVHGEYHPSLYRILGMPTEVFC
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8472954 [H]