Click here to switch to the map view.

The map label for this gene is thrC [H]

Identifier: 17230785

GI number: 17230785

Start: 3975897

End: 3977201

Strand: Direct

Name: thrC [H]

Synonym: alr3293

Alternate gene names: 17230785

Gene position: 3975897-3977201 (Clockwise)

Preceding gene: 17230779

Following gene: 17230786

Centisome position: 61.99

GC content: 46.36

Gene sequence:

>1305_bases
ATGACGCAGGCAACATCTACACCCACCCAAACGACCAATGCCACCCTTTCAGCGTTGAAGTGTAAGGAATGTGGCGCAGA
ATATGAACTGAAAGCTACTCATGTGTGTGAGTATTGTTTTGGCCCGTTGGAAGTGAAGTATGACTACAATGCCTTACGTC
TCTCTGTTACCCGCGAAAAAATTCAAGCTGGGCCAAACTCAATTTGGCGTTATCGCCCTTTTCTGCCTGTCACAACTGAC
AATGTAATTGATGTGGGAACAGGTATGACTCCCCTGGTGCGTTCCCATCGTCTTGCCCGTCGCCTGGGTCTAAACAAGCT
TTACATTAAAAATGATGCAGTGAATATGCCCACCCTCAGCTTTAAGGATCGGGTGGTATCCGTCGCCCTGTCTCGCGCTA
GAGAGTTGGGATTCACCACAGTTTCTTGCGCTAGCACTGGTAACTTAGCAAATTCTACAGCAGCGATCGCCGCCCATGCC
GGTTTAGATTGCTGTGTGTTCATCCCCGCAGATTTAGAAGCTGGCAAAATTCTGGGTAGCTTAATCTACAGTCCTACCCT
CATGGCGGTGAAAGGCAACTATGATCAAGTCAATCGCCTTTGTTCGGAAGTAGCTAATACACACGGTTGGGGCTTTGTCA
ATATTAACTTACGCCCCTACTATTCCGAAGGTTCCAAGACTTTGGGCTTTGAAGTTGCCGAACAACTAGGCTGGGAACTA
CCAGATCATATAGTTGCACCTTTGGCTTCTGGTTCACTGTTCACCAAAATCTATAAAGGCTTCCAGGAATTCGTGGAAGT
TGGTTTGGTGGAAGGGAAGAAAGTCCGTTTCAGTGGCGCACAGGCGGAAGGTTGTTCACCCATCGCCCAAGCCTTTAAAG
AAGACAGAGACTTTATTAAACCAGTGAAACCGAATACAATTGCCAAATCAATTGCGATCGGTAATCCAGCAGATGGTGTT
TATGCTGTTGATATTGCCAAGAAAACTGGCGGTAATATTGAATCAGTGAATGATGCAGAAATTATCGAAGGTATCAAGCT
ACTGGCAGAAACCGAAGGCATCTTTACAGAAACAGCTGGTGGTACAACTGTTGCTGTGCTGAAAAAATTGGTAGAAGCTG
GCAAAATTGATCCAGACGAAACCACCGTGGTTTACATCACTGGCAATGGTTTGAAAACCCAAGAAGCCGTACAAGGCTAC
GTTGGCGAACCTTTGACAATTGATGCCAAATTAGATAGTTTTGAGCGTGCTTTAGAGCGTTCACGTACCCTCGACCGCTT
GGAATGGCAACAAGTCCTCGTTTAG

Upstream 100 bases:

>100_bases
AGGAAATACCCGACAAAAATTATCGGGTATGTTTGACTAGTGTTTTTACCCGTGTTACTATCAACGACAGTTGACGGACA
AACAGGGAAAGCTAGTTATT

Downstream 100 bases:

>100_bases
TAATTAGTCAGTGGTCATTAGAAACTAACAACCGACCACTGTCAACTGTCAACTGACCAATAATTAATTAACTATGGCTG
TAAAAGTTTTAGTCCCTACC

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MTQATSTPTQTTNATLSALKCKECGAEYELKATHVCEYCFGPLEVKYDYNALRLSVTREKIQAGPNSIWRYRPFLPVTTD
NVIDVGTGMTPLVRSHRLARRLGLNKLYIKNDAVNMPTLSFKDRVVSVALSRARELGFTTVSCASTGNLANSTAAIAAHA
GLDCCVFIPADLEAGKILGSLIYSPTLMAVKGNYDQVNRLCSEVANTHGWGFVNINLRPYYSEGSKTLGFEVAEQLGWEL
PDHIVAPLASGSLFTKIYKGFQEFVEVGLVEGKKVRFSGAQAEGCSPIAQAFKEDRDFIKPVKPNTIAKSIAIGNPADGV
YAVDIAKKTGGNIESVNDAEIIEGIKLLAETEGIFTETAGGTTVAVLKKLVEAGKIDPDETTVVYITGNGLKTQEAVQGY
VGEPLTIDAKLDSFERALERSRTLDRLEWQQVLV

Sequences:

>Translated_434_residues
MTQATSTPTQTTNATLSALKCKECGAEYELKATHVCEYCFGPLEVKYDYNALRLSVTREKIQAGPNSIWRYRPFLPVTTD
NVIDVGTGMTPLVRSHRLARRLGLNKLYIKNDAVNMPTLSFKDRVVSVALSRARELGFTTVSCASTGNLANSTAAIAAHA
GLDCCVFIPADLEAGKILGSLIYSPTLMAVKGNYDQVNRLCSEVANTHGWGFVNINLRPYYSEGSKTLGFEVAEQLGWEL
PDHIVAPLASGSLFTKIYKGFQEFVEVGLVEGKKVRFSGAQAEGCSPIAQAFKEDRDFIKPVKPNTIAKSIAIGNPADGV
YAVDIAKKTGGNIESVNDAEIIEGIKLLAETEGIFTETAGGTTVAVLKKLVEAGKIDPDETTVVYITGNGLKTQEAVQGY
VGEPLTIDAKLDSFERALERSRTLDRLEWQQVLV
>Mature_433_residues
TQATSTPTQTTNATLSALKCKECGAEYELKATHVCEYCFGPLEVKYDYNALRLSVTREKIQAGPNSIWRYRPFLPVTTDN
VIDVGTGMTPLVRSHRLARRLGLNKLYIKNDAVNMPTLSFKDRVVSVALSRARELGFTTVSCASTGNLANSTAAIAAHAG
LDCCVFIPADLEAGKILGSLIYSPTLMAVKGNYDQVNRLCSEVANTHGWGFVNINLRPYYSEGSKTLGFEVAEQLGWELP
DHIVAPLASGSLFTKIYKGFQEFVEVGLVEGKKVRFSGAQAEGCSPIAQAFKEDRDFIKPVKPNTIAKSIAIGNPADGVY
AVDIAKKTGGNIESVNDAEIIEGIKLLAETEGIFTETAGGTTVAVLKKLVEAGKIDPDETTVVYITGNGLKTQEAVQGYV
GEPLTIDAKLDSFERALERSRTLDRLEWQQVLV

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 47057; Mature: 46926

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00063 ALDOKETO_REDUCTASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQATSTPTQTTNATLSALKCKECGAEYELKATHVCEYCFGPLEVKYDYNALRLSVTREK
CCCCCCCCCCCCCHHHHHHHHHHCCCCCEEHHHHHHHHCCCCEEEEECCCEEEEEEEHHH
IQAGPNSIWRYRPFLPVTTDNVIDVGTGMTPLVRSHRLARRLGLNKLYIKNDAVNMPTLS
HHCCCCCCEEECCCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCC
FKDRVVSVALSRARELGFTTVSCASTGNLANSTAAIAAHAGLDCCVFIPADLEAGKILGS
HHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHCCCCEEEEECCCCCHHHHHHH
LIYSPTLMAVKGNYDQVNRLCSEVANTHGWGFVNINLRPYYSEGSKTLGFEVAEQLGWEL
HHCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCHHHHHHHHCCCCC
PDHIVAPLASGSLFTKIYKGFQEFVEVGLVEGKKVRFSGAQAEGCSPIAQAFKEDRDFIK
CHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCC
PVKPNTIAKSIAIGNPADGVYAVDIAKKTGGNIESVNDAEIIEGIKLLAETEGIFTETAG
CCCCCHHHHHEECCCCCCCEEEEEEEHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCC
GTTVAVLKKLVEAGKIDPDETTVVYITGNGLKTQEAVQGYVGEPLTIDAKLDSFERALER
CHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHCCCCEEEECCHHHHHHHHHH
SRTLDRLEWQQVLV
HHHHHHHHHHHHCC
>Mature Secondary Structure 
TQATSTPTQTTNATLSALKCKECGAEYELKATHVCEYCFGPLEVKYDYNALRLSVTREK
CCCCCCCCCCCCHHHHHHHHHHCCCCCEEHHHHHHHHCCCCEEEEECCCEEEEEEEHHH
IQAGPNSIWRYRPFLPVTTDNVIDVGTGMTPLVRSHRLARRLGLNKLYIKNDAVNMPTLS
HHCCCCCCEEECCCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCC
FKDRVVSVALSRARELGFTTVSCASTGNLANSTAAIAAHAGLDCCVFIPADLEAGKILGS
HHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHCCCCEEEEECCCCCHHHHHHH
LIYSPTLMAVKGNYDQVNRLCSEVANTHGWGFVNINLRPYYSEGSKTLGFEVAEQLGWEL
HHCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCHHHHHHHHCCCCC
PDHIVAPLASGSLFTKIYKGFQEFVEVGLVEGKKVRFSGAQAEGCSPIAQAFKEDRDFIK
CHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCC
PVKPNTIAKSIAIGNPADGVYAVDIAKKTGGNIESVNDAEIIEGIKLLAETEGIFTETAG
CCCCCHHHHHEECCCCCCCEEEEEEEHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCC
GTTVAVLKKLVEAGKIDPDETTVVYITGNGLKTQEAVQGYVGEPLTIDAKLDSFERALER
CHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHCCCCEEEECCHHHHHHHHHH
SRTLDRLEWQQVLV
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]