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The map label for this gene is tadA [H]

Identifier: 17230776

GI number: 17230776

Start: 3959686

End: 3960117

Strand: Reverse

Name: tadA [H]

Synonym: all3284

Alternate gene names: 17230776

Gene position: 3960117-3959686 (Counterclockwise)

Preceding gene: 17230778

Following gene: 17230774

Centisome position: 61.74

GC content: 42.13

Gene sequence:

>432_bases
ATGGATGAGTTTATGCAGGCCGCCATTCAAGAAGCAAAACAAGGTAGACAAGAAGGAGGTATTCCCATTGGTTCCGTGCT
TGTCAAAGATGGCAAAATTCTCGGCAGAGGACATAACAAACGTGTACAAGACCGTGACCCTGTTACTCATGCCGAAATCG
ATTGTCTCCGTAATGCCGGTAGAATTGGCAGTTACAGAGGTACCACATTATATTCAACCTTAATGCCGTGTTATTTATGC
GCTGGGGCTGTGGTGCAATTTGGTATTAAGAAAGTCATTGTCGGTGAATCTAGGACTTTTCCTGGTGCTAAAGATTTTAT
GGTGTCCCACGGTGTGGAAGTTATTGATTTAAATTTAGATGAATGCGAACAGATGATGAGTGAGTTTGTTCAAACCAATC
CTGAACTATGGAATGAGGATATAGGCAATTAG

Upstream 100 bases:

>100_bases
ATTATCCATCGTCAACAGCAGCATAGTTGCTAGATAATCATCTACACCACCATCATGATCCATTAACACTAGTTGTTTTG
TCATATAAGGAGGATAAAAA

Downstream 100 bases:

>100_bases
ATGTTTTTCATAACTACGAAACACAAAGCTTTCACCAAACCTCTGTGTCCCTCCGCATAAACTTTGAACCTCCTCTGTGT
TCAAAAATAGAAAAATGCCG

Product: cytosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MDEFMQAAIQEAKQGRQEGGIPIGSVLVKDGKILGRGHNKRVQDRDPVTHAEIDCLRNAGRIGSYRGTTLYSTLMPCYLC
AGAVVQFGIKKVIVGESRTFPGAKDFMVSHGVEVIDLNLDECEQMMSEFVQTNPELWNEDIGN

Sequences:

>Translated_143_residues
MDEFMQAAIQEAKQGRQEGGIPIGSVLVKDGKILGRGHNKRVQDRDPVTHAEIDCLRNAGRIGSYRGTTLYSTLMPCYLC
AGAVVQFGIKKVIVGESRTFPGAKDFMVSHGVEVIDLNLDECEQMMSEFVQTNPELWNEDIGN
>Mature_143_residues
MDEFMQAAIQEAKQGRQEGGIPIGSVLVKDGKILGRGHNKRVQDRDPVTHAEIDCLRNAGRIGSYRGTTLYSTLMPCYLC
AGAVVQFGIKKVIVGESRTFPGAKDFMVSHGVEVIDLNLDECEQMMSEFVQTNPELWNEDIGN

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Escherichia coli, GI145693172, Length=140, Percent_Identity=34.2857142857143, Blast_Score=84, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17554608, Length=99, Percent_Identity=39.3939393939394, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17541138, Length=108, Percent_Identity=32.4074074074074, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325319, Length=143, Percent_Identity=41.958041958042, Blast_Score=122, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 15789; Mature: 15789

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEFMQAAIQEAKQGRQEGGIPIGSVLVKDGKILGRGHNKRVQDRDPVTHAEIDCLRNAG
CCHHHHHHHHHHHHHHHHCCCCHHHEEEECCEEEECCCCCCCCCCCCCHHHHHHHHHCCC
RIGSYRGTTLYSTLMPCYLCAGAVVQFGIKKVIVGESRTFPGAKDFMVSHGVEVIDLNLD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEECCHH
ECEQMMSEFVQTNPELWNEDIGN
HHHHHHHHHHHCCHHHHHCCCCC
>Mature Secondary Structure
MDEFMQAAIQEAKQGRQEGGIPIGSVLVKDGKILGRGHNKRVQDRDPVTHAEIDCLRNAG
CCHHHHHHHHHHHHHHHHCCCCHHHEEEECCEEEECCCCCCCCCCCCCHHHHHHHHHCCC
RIGSYRGTTLYSTLMPCYLCAGAVVQFGIKKVIVGESRTFPGAKDFMVSHGVEVIDLNLD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEECCHH
ECEQMMSEFVQTNPELWNEDIGN
HHHHHHHHHHHCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]