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The map label for this gene is yycF [H]

Identifier: 17230752

GI number: 17230752

Start: 3933567

End: 3934283

Strand: Direct

Name: yycF [H]

Synonym: alr3260

Alternate gene names: 17230752

Gene position: 3933567-3934283 (Clockwise)

Preceding gene: 17230750

Following gene: 161353744

Centisome position: 61.33

GC content: 46.16

Gene sequence:

>717_bases
ATGGCTCCTGCCAAGATTCTTGTAGTTGATGACGACCCTGCGGTTCGGAATTTAATCCAACGCTTTTTGATAAAGCAAAA
CTATCAGGTGGAGGCTGCCGAAGATGGTAAGACAGCCTTATCTCTATTTGAGCAATTTAACCCAGATTTGGTAATTTTGG
ATATCAACTTACCAGATGTCATTGGGTTTAACCTCTGCCAAGAGATGCAAAGTCGTAATGGTGTTTTTGTTCTGATGCTC
ACTAGCCGTGCGGACGAAGCTGACAAGATTCGCGGCTTTGCTAAGGGTGCTGATGACTACCTCACCAAACCCTTTGGTCT
AGGAGAACTAGAAGTCAGAGTCGGAGCTATTTTAAGAAGACAGCGCGTTGTCACCACCGCAGAACAGAAACGGTTAACAT
TTGAAAAACTGATGATTGACCCTGTACGGCGAGAGGTGACACTTAACAGCCAAGCTGTACCCTTAACTGCTCTAGAATTT
GATCTGTTACATTTCTTAGCCAGCCATCCTGGCCGAGTGTGGCGACGCGCCGAACTAATTCAAGAGGTCTGGGACTACGA
ATATGTAGGCGACCAGCGAGTTGTAGACGTACATATCGGTCAAATTCGCAAAAAGATCGAAGTGGACGCTAGCCAACCAG
CATTGATTCAGACTGTGCGCGGGGTAGGGTATAAATTTGAATGTCCCACTCACTCCCAAGTAGAAACCAATGCTTGA

Upstream 100 bases:

>100_bases
AATCCTGAGTTTTGTAGTTTCTTAAATATTCCCAAGTAGAAACTGCGTTTTTACGCCATACTGCTGTTAATCTTATTAAT
TTTTGTGCAAAGTGATGGTC

Downstream 100 bases:

>100_bases
ATGTGTGGTTCATAGTCTAGGTTTAAATAATTATTTTTACACTTAGACTAGATAATTTCTGCCTATAGTTAAAAACTAGA
TTAATCAAATCGCTCAAAGA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MAPAKILVVDDDPAVRNLIQRFLIKQNYQVEAAEDGKTALSLFEQFNPDLVILDINLPDVIGFNLCQEMQSRNGVFVLML
TSRADEADKIRGFAKGADDYLTKPFGLGELEVRVGAILRRQRVVTTAEQKRLTFEKLMIDPVRREVTLNSQAVPLTALEF
DLLHFLASHPGRVWRRAELIQEVWDYEYVGDQRVVDVHIGQIRKKIEVDASQPALIQTVRGVGYKFECPTHSQVETNA

Sequences:

>Translated_238_residues
MAPAKILVVDDDPAVRNLIQRFLIKQNYQVEAAEDGKTALSLFEQFNPDLVILDINLPDVIGFNLCQEMQSRNGVFVLML
TSRADEADKIRGFAKGADDYLTKPFGLGELEVRVGAILRRQRVVTTAEQKRLTFEKLMIDPVRREVTLNSQAVPLTALEF
DLLHFLASHPGRVWRRAELIQEVWDYEYVGDQRVVDVHIGQIRKKIEVDASQPALIQTVRGVGYKFECPTHSQVETNA
>Mature_237_residues
APAKILVVDDDPAVRNLIQRFLIKQNYQVEAAEDGKTALSLFEQFNPDLVILDINLPDVIGFNLCQEMQSRNGVFVLMLT
SRADEADKIRGFAKGADDYLTKPFGLGELEVRVGAILRRQRVVTTAEQKRLTFEKLMIDPVRREVTLNSQAVPLTALEFD
LLHFLASHPGRVWRRAELIQEVWDYEYVGDQRVVDVHIGQIRKKIEVDASQPALIQTVRGVGYKFECPTHSQVETNA

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=35.2422907488987, Blast_Score=150, Evalue=6e-38,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=38.0530973451327, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=36.1233480176211, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=34.2342342342342, Blast_Score=137, Evalue=4e-34,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=33.1838565022422, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=34.468085106383, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=34.2342342342342, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=32, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=32.4324324324324, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=34.3478260869565, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=36, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=30.3964757709251, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=33.6283185840708, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=33.0357142857143, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788550, Length=120, Percent_Identity=34.1666666666667, Blast_Score=77, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26989; Mature: 26858

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPAKILVVDDDPAVRNLIQRFLIKQNYQVEAAEDGKTALSLFEQFNPDLVILDINLPDV
CCCCEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCEEEEECCCCHH
IGFNLCQEMQSRNGVFVLMLTSRADEADKIRGFAKGADDYLTKPFGLGELEVRVGAILRR
HHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHH
QRVVTTAEQKRLTFEKLMIDPVRREVTLNSQAVPLTALEFDLLHFLASHPGRVWRRAELI
HHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHH
QEVWDYEYVGDQRVVDVHIGQIRKKIEVDASQPALIQTVRGVGYKFECPTHSQVETNA
HHHHCCCCCCCCEEEEEEHHHHHHHHCCCCCCCHHHHHHHCCCEEEECCCCCCCCCCC
>Mature Secondary Structure 
APAKILVVDDDPAVRNLIQRFLIKQNYQVEAAEDGKTALSLFEQFNPDLVILDINLPDV
CCCEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCEEEEECCCCHH
IGFNLCQEMQSRNGVFVLMLTSRADEADKIRGFAKGADDYLTKPFGLGELEVRVGAILRR
HHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHH
QRVVTTAEQKRLTFEKLMIDPVRREVTLNSQAVPLTALEFDLLHFLASHPGRVWRRAELI
HHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHH
QEVWDYEYVGDQRVVDVHIGQIRKKIEVDASQPALIQTVRGVGYKFECPTHSQVETNA
HHHHCCCCCCCCEEEEEEHHHHHHHHCCCCCCCHHHHHHHCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]