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The map label for this gene is hpuB [H]

Identifier: 17230734

GI number: 17230734

Start: 3914423

End: 3917056

Strand: Direct

Name: hpuB [H]

Synonym: alr3242

Alternate gene names: 17230734

Gene position: 3914423-3917056 (Clockwise)

Preceding gene: 17230733

Following gene: 17230735

Centisome position: 61.03

GC content: 39.33

Gene sequence:

>2634_bases
ATGAAATATTATTTGTTCACAGCAGTTTTGGCGGTGACAATTCCTATAGCTGCACTGGGAAATGAAATACCAGTCAATAA
TAATCCAGTTAATCAGGTAGAAAATGCCAAGTTAACTGAAATCAAAGCCATTAATCTTGAGGAAGTTGACAAAGGAATCA
GCATCATCATAGAAACAGCTAGTGGAGAAATTCCTGAAGGGGAAATTATTGAAAATAGCACCGACGTAGTTATTAAATTA
AGCAATGTCAAACTAAATCTTCCTGACGGTAATAACTTCATCAAAGATAAACCCATTCCGGGAATCAATTCTCTCACCGT
TACTCAACAATCTGCAACAGAAGTAGAAATCAAAATCGTTGGAGATGGAACATTACCAAACGTTGAACAACGAGAAAGTC
AAAAGGGACTGGCGTTGAGTGTCATACCCACACCTAAAGCAGTAGCAGCAGAAAATACCATAGAACTCAACGTCGTGGGA
AACCGTGACGCAAATGAAACAGCACCGGCTAACGTCACCATTATCGATAGGGAACAAATAGAAAAACAACAAGCGCGAGA
TGTCAGAGACTTATTGCGTTATGAACCAGGGATTTCCGTACCCTATGACAGTCGCGGTGGTTTACAAGGAATCAACTTGC
GAGGGTTGAGTGGAAATCGCGTCAATCTGCAAGTAGATGGTATTCGTCTACCTTATGAATATAGCTATGGTGCTACTCGT
TTGGGTAGAGACTTTGTAGATATTGAAACCTTAAACGCTTTAGAAATTTTCCGAGGAAATAATTCCGCAGTATTAGGAAG
TGACGCGTTAGGTGGAACAGTTAATTTTGCAACCGCTAGAACTGGAAGTCTATTAGAGAATATTGGTAAAGACTCTTATA
CAAGTGTTCGCGCACAATATAGTAGTAAAGATAGCGGTTTTGTCGGAACATTTGTCCAAGCAAATCGGTTGGATAATATC
GACACTCTATTTATCTATACCCGACGTGATAGTGGGTCACTAAAAGTAGCTGGAGGAAACAGCATTTATCAAGATGACCA
AGATAGAACCCGCAATAACTTTCTAGGAAAATTAACTTATAACTTTAACCAGGAAAGTTTTCTGGAATTGACTGGAGAAT
ATTTCAACAACATTACTGATAGTCGATTCTCCACCGCCAACTTACCAGGAATGGTGTTTGAAGCTTCAACTCAAGATTTA
CAAGAAGAAGTCACAACAACTCGTAGCAGATTTAGTCTGGGATATCAATACGATAATCCCAACAGCAAATCATGGTTGCA
ATTTGTCCGTGCGAATCTTTATTACCAAAATGCAATTATCGAAGAAGATAGTAACAGGAGTGTCCGCAGTGCGGGAACTA
TCAGAACAGAAGCAGCAGATAAGGATTTAACCGACAGAATTTTTGGGGCAAATGTTCAACTCCGCAGTGATTTTAATATA
GGGGATATCAAAAATAGTCTCACCTCTGGGTTAGAAATTTCCCACAACTACAACGAACGCAATTACTTTAACTTTATTAC
CACCACAGGCACAAGAGTAAATGCAGCCGGATTCCCCCAGAAAGACTTTCCTGATAGCGATACTTTCCGCCTTGGTACTT
ACTTACAAAATGAAATTTCCTTTGGTGATGGTAAAGTAAAATTAATCCCTGGCTTGCGCTTTGATGTTTACAACTTAAGC
ACAGCAAATAATCCTGAATTTACACAAAAACAGCAAGGCGTTGACGCGGTAAATTATTCCACATCTGCACTTTCTCCCAG
CTTAGGAATTGTCTATGAACCATCTCCAGGATTAACATTATTTAGTAGATATTCCCGTGGGTTTCGTCCCCCACTATATA
GCGAACTAAATTTTGCTTTTCGCGCTGATATTCCATTACGCCCCCATAAAGGTATTTCTAACCCCAATTTACAAGCAGAA
ACCAGCAATAACTTTGAACTAGGATTACGTAGCCGTTCCCAACAATTTGATTTTGATATTACTGGCTTCTACAACCGTTA
TAGAAACTTCATTGAACCATCTGTATTTGTTGGTTTTGACACCAATGATTTCGGGACATTTAGAACGGCTGGAAGAGCGA
TTCCTTTCCAGATTTTTCAGGCGCAGAATATACCAGATGCAGAAATTTTTGGCTTAGAAATTAAAACAGCTTACCGATTT
AGTCCAGAACCTGGTGGTTTTAGCTTAAAAGGCGCTTTAGGTTGGCAAATTGGTAATGATTTAACCAAAGATATCCCCTT
AACTACGATTAATCCTTTACAAGCAGTTATTGGTTTAGGATATCAGTCCCCAAATGATACATGGGGTGCAGAATTAATCG
GTACTTTTGTCGCCCAAGCTAGAGAACAAGCATTAGTTGATGACCAAACTAGTGTACAGAATGGTGGACAAGCAACCAGA
AAAATCGATTTTTATGAACCTGATGCTTATACCTTAGTGGATCTTGTTGGTTACTACAATATCAATCCCCATCTCACATT
AACGGCTGGTGTTTATAACATCTTCAATACTGAATATTATCAGTATGCGGATGTGCGGACAATTAATAGTAATGCTACCG
CTTTTGCGGCGCAACGGGGGCGTTATGCTCAACCTGGGACAAATTTCGCTATTAGTTTGAATTGGAGATTTTGA

Upstream 100 bases:

>100_bases
TAAATAGATGAAGGTAAATATTATGACTTCATTTTGCCATTAATCATCATATTAATGGCGTAATTTTCATGCGTCTTAAT
TTTTTTGCTGAGGAGAATTC

Downstream 100 bases:

>100_bases
AGAGATTAGTCATGAATAAACATCTGATATTATGGGCGATGTCTTTTTTGGTGACTGTTAATTTATGGGGTTGTGCAAAT
AATCCAAATAACTCTACAGC

Product: heme transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 877; Mature: 877

Protein sequence:

>877_residues
MKYYLFTAVLAVTIPIAALGNEIPVNNNPVNQVENAKLTEIKAINLEEVDKGISIIIETASGEIPEGEIIENSTDVVIKL
SNVKLNLPDGNNFIKDKPIPGINSLTVTQQSATEVEIKIVGDGTLPNVEQRESQKGLALSVIPTPKAVAAENTIELNVVG
NRDANETAPANVTIIDREQIEKQQARDVRDLLRYEPGISVPYDSRGGLQGINLRGLSGNRVNLQVDGIRLPYEYSYGATR
LGRDFVDIETLNALEIFRGNNSAVLGSDALGGTVNFATARTGSLLENIGKDSYTSVRAQYSSKDSGFVGTFVQANRLDNI
DTLFIYTRRDSGSLKVAGGNSIYQDDQDRTRNNFLGKLTYNFNQESFLELTGEYFNNITDSRFSTANLPGMVFEASTQDL
QEEVTTTRSRFSLGYQYDNPNSKSWLQFVRANLYYQNAIIEEDSNRSVRSAGTIRTEAADKDLTDRIFGANVQLRSDFNI
GDIKNSLTSGLEISHNYNERNYFNFITTTGTRVNAAGFPQKDFPDSDTFRLGTYLQNEISFGDGKVKLIPGLRFDVYNLS
TANNPEFTQKQQGVDAVNYSTSALSPSLGIVYEPSPGLTLFSRYSRGFRPPLYSELNFAFRADIPLRPHKGISNPNLQAE
TSNNFELGLRSRSQQFDFDITGFYNRYRNFIEPSVFVGFDTNDFGTFRTAGRAIPFQIFQAQNIPDAEIFGLEIKTAYRF
SPEPGGFSLKGALGWQIGNDLTKDIPLTTINPLQAVIGLGYQSPNDTWGAELIGTFVAQAREQALVDDQTSVQNGGQATR
KIDFYEPDAYTLVDLVGYYNINPHLTLTAGVYNIFNTEYYQYADVRTINSNATAFAAQRGRYAQPGTNFAISLNWRF

Sequences:

>Translated_877_residues
MKYYLFTAVLAVTIPIAALGNEIPVNNNPVNQVENAKLTEIKAINLEEVDKGISIIIETASGEIPEGEIIENSTDVVIKL
SNVKLNLPDGNNFIKDKPIPGINSLTVTQQSATEVEIKIVGDGTLPNVEQRESQKGLALSVIPTPKAVAAENTIELNVVG
NRDANETAPANVTIIDREQIEKQQARDVRDLLRYEPGISVPYDSRGGLQGINLRGLSGNRVNLQVDGIRLPYEYSYGATR
LGRDFVDIETLNALEIFRGNNSAVLGSDALGGTVNFATARTGSLLENIGKDSYTSVRAQYSSKDSGFVGTFVQANRLDNI
DTLFIYTRRDSGSLKVAGGNSIYQDDQDRTRNNFLGKLTYNFNQESFLELTGEYFNNITDSRFSTANLPGMVFEASTQDL
QEEVTTTRSRFSLGYQYDNPNSKSWLQFVRANLYYQNAIIEEDSNRSVRSAGTIRTEAADKDLTDRIFGANVQLRSDFNI
GDIKNSLTSGLEISHNYNERNYFNFITTTGTRVNAAGFPQKDFPDSDTFRLGTYLQNEISFGDGKVKLIPGLRFDVYNLS
TANNPEFTQKQQGVDAVNYSTSALSPSLGIVYEPSPGLTLFSRYSRGFRPPLYSELNFAFRADIPLRPHKGISNPNLQAE
TSNNFELGLRSRSQQFDFDITGFYNRYRNFIEPSVFVGFDTNDFGTFRTAGRAIPFQIFQAQNIPDAEIFGLEIKTAYRF
SPEPGGFSLKGALGWQIGNDLTKDIPLTTINPLQAVIGLGYQSPNDTWGAELIGTFVAQAREQALVDDQTSVQNGGQATR
KIDFYEPDAYTLVDLVGYYNINPHLTLTAGVYNIFNTEYYQYADVRTINSNATAFAAQRGRYAQPGTNFAISLNWRF
>Mature_877_residues
MKYYLFTAVLAVTIPIAALGNEIPVNNNPVNQVENAKLTEIKAINLEEVDKGISIIIETASGEIPEGEIIENSTDVVIKL
SNVKLNLPDGNNFIKDKPIPGINSLTVTQQSATEVEIKIVGDGTLPNVEQRESQKGLALSVIPTPKAVAAENTIELNVVG
NRDANETAPANVTIIDREQIEKQQARDVRDLLRYEPGISVPYDSRGGLQGINLRGLSGNRVNLQVDGIRLPYEYSYGATR
LGRDFVDIETLNALEIFRGNNSAVLGSDALGGTVNFATARTGSLLENIGKDSYTSVRAQYSSKDSGFVGTFVQANRLDNI
DTLFIYTRRDSGSLKVAGGNSIYQDDQDRTRNNFLGKLTYNFNQESFLELTGEYFNNITDSRFSTANLPGMVFEASTQDL
QEEVTTTRSRFSLGYQYDNPNSKSWLQFVRANLYYQNAIIEEDSNRSVRSAGTIRTEAADKDLTDRIFGANVQLRSDFNI
GDIKNSLTSGLEISHNYNERNYFNFITTTGTRVNAAGFPQKDFPDSDTFRLGTYLQNEISFGDGKVKLIPGLRFDVYNLS
TANNPEFTQKQQGVDAVNYSTSALSPSLGIVYEPSPGLTLFSRYSRGFRPPLYSELNFAFRADIPLRPHKGISNPNLQAE
TSNNFELGLRSRSQQFDFDITGFYNRYRNFIEPSVFVGFDTNDFGTFRTAGRAIPFQIFQAQNIPDAEIFGLEIKTAYRF
SPEPGGFSLKGALGWQIGNDLTKDIPLTTINPLQAVIGLGYQSPNDTWGAELIGTFVAQAREQALVDDQTSVQNGGQATR
KIDFYEPDAYTLVDLVGYYNINPHLTLTAGVYNIFNTEYYQYADVRTINSNATAFAAQRGRYAQPGTNFAISLNWRF

Specific function: Acts as a receptor for hemoglobin or the hemoglobin/haptoglobin complex and is required for heme uptake [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786798, Length=449, Percent_Identity=24.4988864142539, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788478, Length=157, Percent_Identity=30.5732484076433, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI1790405, Length=128, Percent_Identity=35.15625, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010949
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 97262; Mature: 97262

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
0.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYYLFTAVLAVTIPIAALGNEIPVNNNPVNQVENAKLTEIKAINLEEVDKGISIIIETA
CEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHCCCEEEEEECC
SGEIPEGEIIENSTDVVIKLSNVKLNLPDGNNFIKDKPIPGINSLTVTQQSATEVEIKIV
CCCCCCCCEEECCCCEEEEEECEEEECCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEE
GDGTLPNVEQRESQKGLALSVIPTPKAVAAENTIELNVVGNRDANETAPANVTIIDREQI
ECCCCCCCHHHHCCCCCEEEEECCCCCEECCCEEEEEEEECCCCCCCCCCEEEEEEHHHH
EKQQARDVRDLLRYEPGISVPYDSRGGLQGINLRGLSGNRVNLQVDGIRLPYEYSYGATR
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCEECCEECCCCCHH
LGRDFVDIETLNALEIFRGNNSAVLGSDALGGTVNFATARTGSLLENIGKDSYTSVRAQY
HCCCEEEEEECCEEEEEECCCCEEEECCCCCCEEEEEECCCHHHHHHCCCCCHHHHEEEC
SSKDSGFVGTFVQANRLDNIDTLFIYTRRDSGSLKVAGGNSIYQDDQDRTRNNFLGKLTY
CCCCCCEEEEEEECCCCCCCEEEEEEEECCCCCEEEECCCCCCCCCCHHHHCCEEEEEEE
NFNQESFLELTGEYFNNITDSRFSTANLPGMVFEASTQDLQEEVTTTRSRFSLGYQYDNP
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHEEEEEEECCC
NSKSWLQFVRANLYYQNAIIEEDSNRSVRSAGTIRTEAADKDLTDRIFGANVQLRSDFNI
CHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCEEECCCCCCHHHHHHCCCEEEECCCCH
GDIKNSLTSGLEISHNYNERNYFNFITTTGTRVNAAGFPQKDFPDSDTFRLGTYLQNEIS
HHHHHHHHCCEEEECCCCCCEEEEEEEECCCEEECCCCCCCCCCCCCCEEEHHHHHCCCC
FGDGKVKLIPGLRFDVYNLSTANNPEFTQKQQGVDAVNYSTSALSPSLGIVYEPSPGLTL
CCCCEEEEECCCEEEEEECCCCCCCCHHHHHCCCCEECCCHHHCCCCCCEEECCCCCCHH
FSRYSRGFRPPLYSELNFAFRADIPLRPHKGISNPNLQAETSNNFELGLRSRSQQFDFDI
HHHHCCCCCCCCHHCCCEEEEECCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCEEE
TGFYNRYRNFIEPSVFVGFDTNDFGTFRTAGRAIPFQIFQAQNIPDAEIFGLEIKTAYRF
HHHHHHHHHHCCCEEEEEECCCCCCCHHHCCCCCCEEEEECCCCCCCEEEEEEEEEEEEE
SPEPGGFSLKGALGWQIGNDLTKDIPLTTINPLQAVIGLGYQSPNDTWGAELIGTFVAQA
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
REQALVDDQTSVQNGGQATRKIDFYEPDAYTLVDLVGYYNINPHLTLTAGVYNIFNTEYY
HHHHHCCCCHHHCCCCCCEEEEEEECCCCEEEEEEHEEECCCCCEEEEECEEEHHCCCEE
QYADVRTINSNATAFAAQRGRYAQPGTNFAISLNWRF
EEEEEEEECCCCEEEHHHCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MKYYLFTAVLAVTIPIAALGNEIPVNNNPVNQVENAKLTEIKAINLEEVDKGISIIIETA
CEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHCCCEEEEEECC
SGEIPEGEIIENSTDVVIKLSNVKLNLPDGNNFIKDKPIPGINSLTVTQQSATEVEIKIV
CCCCCCCCEEECCCCEEEEEECEEEECCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEE
GDGTLPNVEQRESQKGLALSVIPTPKAVAAENTIELNVVGNRDANETAPANVTIIDREQI
ECCCCCCCHHHHCCCCCEEEEECCCCCEECCCEEEEEEEECCCCCCCCCCEEEEEEHHHH
EKQQARDVRDLLRYEPGISVPYDSRGGLQGINLRGLSGNRVNLQVDGIRLPYEYSYGATR
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCEECCEECCCCCHH
LGRDFVDIETLNALEIFRGNNSAVLGSDALGGTVNFATARTGSLLENIGKDSYTSVRAQY
HCCCEEEEEECCEEEEEECCCCEEEECCCCCCEEEEEECCCHHHHHHCCCCCHHHHEEEC
SSKDSGFVGTFVQANRLDNIDTLFIYTRRDSGSLKVAGGNSIYQDDQDRTRNNFLGKLTY
CCCCCCEEEEEEECCCCCCCEEEEEEEECCCCCEEEECCCCCCCCCCHHHHCCEEEEEEE
NFNQESFLELTGEYFNNITDSRFSTANLPGMVFEASTQDLQEEVTTTRSRFSLGYQYDNP
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHEEEEEEECCC
NSKSWLQFVRANLYYQNAIIEEDSNRSVRSAGTIRTEAADKDLTDRIFGANVQLRSDFNI
CHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCEEECCCCCCHHHHHHCCCEEEECCCCH
GDIKNSLTSGLEISHNYNERNYFNFITTTGTRVNAAGFPQKDFPDSDTFRLGTYLQNEIS
HHHHHHHHCCEEEECCCCCCEEEEEEEECCCEEECCCCCCCCCCCCCCEEEHHHHHCCCC
FGDGKVKLIPGLRFDVYNLSTANNPEFTQKQQGVDAVNYSTSALSPSLGIVYEPSPGLTL
CCCCEEEEECCCEEEEEECCCCCCCCHHHHHCCCCEECCCHHHCCCCCCEEECCCCCCHH
FSRYSRGFRPPLYSELNFAFRADIPLRPHKGISNPNLQAETSNNFELGLRSRSQQFDFDI
HHHHCCCCCCCCHHCCCEEEEECCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCEEE
TGFYNRYRNFIEPSVFVGFDTNDFGTFRTAGRAIPFQIFQAQNIPDAEIFGLEIKTAYRF
HHHHHHHHHHCCCEEEEEECCCCCCCHHHCCCCCCEEEEECCCCCCCEEEEEEEEEEEEE
SPEPGGFSLKGALGWQIGNDLTKDIPLTTINPLQAVIGLGYQSPNDTWGAELIGTFVAQA
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
REQALVDDQTSVQNGGQATRKIDFYEPDAYTLVDLVGYYNINPHLTLTAGVYNIFNTEYY
HHHHHCCCCHHHCCCCCCEEEEEEECCCCEEEEEEHEEECCCCCEEEEECEEEHHCCCEE
QYADVRTINSNATAFAAQRGRYAQPGTNFAISLNWRF
EEEEEEEECCCCEEEHHHCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]