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The map label for this gene is xisA [H]

Identifier: 17230716

GI number: 17230716

Start: 3891088

End: 3892542

Strand: Direct

Name: xisA [H]

Synonym: alr3224

Alternate gene names: 17230716

Gene position: 3891088-3892542 (Clockwise)

Preceding gene: 17230714

Following gene: 17230717

Centisome position: 60.67

GC content: 38.01

Gene sequence:

>1455_bases
ATGCCTGCAATTACTTTTGATCTACGTACATCTGAGTGGGATGGTACACCAATTGACAAGTGGGAACCGTCTAAATGGAA
GCAATGGAAAGCTAAACAAACTGATGAATTGGCCAAGGTAGAACGGGAATACCTGCGAATTAAACACTCCGTACAGCAGG
CAAATGCAGCTTTAAGTCTAGATAGAATCAAGATTAAATTGAAACTTAGCAGCCCTAAAAGTATTGCTTTACAAGGTACT
TTTCCTTGTAGACCTGGGGATGTAGGTAAACAAGGTAGTCCTAATAAGCAATATACCATTTCTTGCGGATTTCCTGCTAA
TGATGCCGGGGTAAAAATGGCTGTTTTGAAAGCACGAGAATTGGATTTATCGTTAATTACAAAACAATTCCAATGGACAC
CGGAGTTACTGGGTAAACAGGCACAAAAGATAGAATTACCAACTCAGAAGAATTCTGGAAAACTCATTGGTGAACTAATT
CAAGAATATGAGCGTGAATTTTGGAAAACTCACGAGCAAAATAGACGAGGGATTCGGACTTGGGAAACTCATTATATGAG
GCATTTAAAAAAACTGCCTCAAGATTTACCAATGTCTGCTCAAGCATTAGAAATAGCCTTAGAGAAAACTAAGCCGAATA
CATCAGCGAGGTTTTTTATGGTATGGCAACTAAAGAAGTTTTGTGAGTTTTGTGGAATTGATGATTTTAAAACAATTTAT
GCCTATGCGACTCCTAAACCTCATCCGGCTATTCGCAAAGTTCCATCGGATGAAGAAGTTATCCAAGGATTTAACAAAAT
TGGTCTGCCTCTATCAGTCTACACGAGTAGAGAGAACACTACACAGCCGGAACAATGGCAATGGGCATACGGGATGCTGG
CTACCTATGGCTTAAGACCCCATGAATTATTTGCTGTGGATATAGAAGCTTTTCTGGAGCCAAAAAATACTTTTCATTTA
GTAAGTTTAAATCCTAGTTTGACAGAAGGGACTAAAACCGGGGAACGGAGTTGTGGAATTCCCCCATTACATCCTCATTG
GGTGGATTTATTCAAGTTAAAGAATATTAGATTTCCCTATAACGAAGGTAAATTGAATAATAAAACTGCCAAACTGTATA
TCAAATTTAGAAATGCAGATATCGGTTTTAGACCTTATGATTTACGTCATGCTTATGCCATACGAGGCCATCGTTTACGA
GTGCCAATAAAGACTATGGCAGATTATATGGGACATACAGTACAAGAACATACTAAAAGTTATCAAAGATGGATGAATGA
AGATACTAATTTAGAGATTTATAAGGAGGTGGTGATTCACAGACAAGGTACTAGTAAAGAAGCAATGAAAGAAAGAATCA
AGGAATTGGAAGCTGAGAACTTGGCTCTCAAAGCTGAAAATGCTACACTTAGGGGTTTATTAGTTCAGCATCAATTGGGT
GAATTGCTAAGTTAA

Upstream 100 bases:

>100_bases
ACACCACAGGCAATTATCACATCACTAGAAAGCACATTAAACTTTACTTCTTGGCTGTTATTAGCTATCTTCAAACCAAG
ACGGTGTTTGAGACTAGCTT

Downstream 100 bases:

>100_bases
GAATAAGTCATTATTTCCAAATCATAACTACTGAGTTTGAATTGATATTGCTGGATGGAGATTGGGCAACATAGATACTA
TAGATGCTGAAGTTAACTTC

Product: hypothetical protein

Products: NA

Alternate protein names: NifD element site-specific recombinase [H]

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MPAITFDLRTSEWDGTPIDKWEPSKWKQWKAKQTDELAKVEREYLRIKHSVQQANAALSLDRIKIKLKLSSPKSIALQGT
FPCRPGDVGKQGSPNKQYTISCGFPANDAGVKMAVLKARELDLSLITKQFQWTPELLGKQAQKIELPTQKNSGKLIGELI
QEYEREFWKTHEQNRRGIRTWETHYMRHLKKLPQDLPMSAQALEIALEKTKPNTSARFFMVWQLKKFCEFCGIDDFKTIY
AYATPKPHPAIRKVPSDEEVIQGFNKIGLPLSVYTSRENTTQPEQWQWAYGMLATYGLRPHELFAVDIEAFLEPKNTFHL
VSLNPSLTEGTKTGERSCGIPPLHPHWVDLFKLKNIRFPYNEGKLNNKTAKLYIKFRNADIGFRPYDLRHAYAIRGHRLR
VPIKTMADYMGHTVQEHTKSYQRWMNEDTNLEIYKEVVIHRQGTSKEAMKERIKELEAENLALKAENATLRGLLVQHQLG
ELLS

Sequences:

>Translated_484_residues
MPAITFDLRTSEWDGTPIDKWEPSKWKQWKAKQTDELAKVEREYLRIKHSVQQANAALSLDRIKIKLKLSSPKSIALQGT
FPCRPGDVGKQGSPNKQYTISCGFPANDAGVKMAVLKARELDLSLITKQFQWTPELLGKQAQKIELPTQKNSGKLIGELI
QEYEREFWKTHEQNRRGIRTWETHYMRHLKKLPQDLPMSAQALEIALEKTKPNTSARFFMVWQLKKFCEFCGIDDFKTIY
AYATPKPHPAIRKVPSDEEVIQGFNKIGLPLSVYTSRENTTQPEQWQWAYGMLATYGLRPHELFAVDIEAFLEPKNTFHL
VSLNPSLTEGTKTGERSCGIPPLHPHWVDLFKLKNIRFPYNEGKLNNKTAKLYIKFRNADIGFRPYDLRHAYAIRGHRLR
VPIKTMADYMGHTVQEHTKSYQRWMNEDTNLEIYKEVVIHRQGTSKEAMKERIKELEAENLALKAENATLRGLLVQHQLG
ELLS
>Mature_483_residues
PAITFDLRTSEWDGTPIDKWEPSKWKQWKAKQTDELAKVEREYLRIKHSVQQANAALSLDRIKIKLKLSSPKSIALQGTF
PCRPGDVGKQGSPNKQYTISCGFPANDAGVKMAVLKARELDLSLITKQFQWTPELLGKQAQKIELPTQKNSGKLIGELIQ
EYEREFWKTHEQNRRGIRTWETHYMRHLKKLPQDLPMSAQALEIALEKTKPNTSARFFMVWQLKKFCEFCGIDDFKTIYA
YATPKPHPAIRKVPSDEEVIQGFNKIGLPLSVYTSRENTTQPEQWQWAYGMLATYGLRPHELFAVDIEAFLEPKNTFHLV
SLNPSLTEGTKTGERSCGIPPLHPHWVDLFKLKNIRFPYNEGKLNNKTAKLYIKFRNADIGFRPYDLRHAYAIRGHRLRV
PIKTMADYMGHTVQEHTKSYQRWMNEDTNLEIYKEVVIHRQGTSKEAMKERIKELEAENLALKAENATLRGLLVQHQLGE
LLS

Specific function: Essential for DNA excision. Site specific recombinase necessary for the excision of the 11 kb nifD element during heterocyst differentiation [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xisA/xisC recombinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 55985; Mature: 55854

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAITFDLRTSEWDGTPIDKWEPSKWKQWKAKQTDELAKVEREYLRIKHSVQQANAALSL
CCCEEEEEECCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEE
DRIKIKLKLSSPKSIALQGTFPCRPGDVGKQGSPNKQYTISCGFPANDAGVKMAVLKARE
EEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEHHHH
LDLSLITKQFQWTPELLGKQAQKIELPTQKNSGKLIGELIQEYEREFWKTHEQNRRGIRT
CCHHHHHHHHCCCHHHHCCCHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHH
WETHYMRHLKKLPQDLPMSAQALEIALEKTKPNTSARFFMVWQLKKFCEFCGIDDFKTIY
HHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHCCCCCEEEE
AYATPKPHPAIRKVPSDEEVIQGFNKIGLPLSVYTSRENTTQPEQWQWAYGMLATYGLRP
EEECCCCCHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCC
HELFAVDIEAFLEPKNTFHLVSLNPSLTEGTKTGERSCGIPPLHPHWVDLFKLKNIRFPY
CCEEEEEHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
NEGKLNNKTAKLYIKFRNADIGFRPYDLRHAYAIRGHRLRVPIKTMADYMGHTVQEHTKS
CCCCCCCCEEEEEEEEECCCCCCCCCCCCHHEEECCCEEECCHHHHHHHHCCHHHHHHHH
YQRWMNEDTNLEIYKEVVIHRQGTSKEAMKERIKELEAENLALKAENATLRGLLVQHQLG
HHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHH
ELLS
HHCC
>Mature Secondary Structure 
PAITFDLRTSEWDGTPIDKWEPSKWKQWKAKQTDELAKVEREYLRIKHSVQQANAALSL
CCEEEEEECCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEE
DRIKIKLKLSSPKSIALQGTFPCRPGDVGKQGSPNKQYTISCGFPANDAGVKMAVLKARE
EEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEHHHH
LDLSLITKQFQWTPELLGKQAQKIELPTQKNSGKLIGELIQEYEREFWKTHEQNRRGIRT
CCHHHHHHHHCCCHHHHCCCHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHH
WETHYMRHLKKLPQDLPMSAQALEIALEKTKPNTSARFFMVWQLKKFCEFCGIDDFKTIY
HHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHCCCCCEEEE
AYATPKPHPAIRKVPSDEEVIQGFNKIGLPLSVYTSRENTTQPEQWQWAYGMLATYGLRP
EEECCCCCHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCC
HELFAVDIEAFLEPKNTFHLVSLNPSLTEGTKTGERSCGIPPLHPHWVDLFKLKNIRFPY
CCEEEEEHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
NEGKLNNKTAKLYIKFRNADIGFRPYDLRHAYAIRGHRLRVPIKTMADYMGHTVQEHTKS
CCCCCCCCEEEEEEEEECCCCCCCCCCCCHHEEECCCEEECCHHHHHHHHCCHHHHHHHH
YQRWMNEDTNLEIYKEVVIHRQGTSKEAMKERIKELEAENLALKAENATLRGLLVQHQLG
HHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHH
ELLS
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3006922; 11759840; 3144039 [H]