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The map label for this gene is cobU [H]

Identifier: 17230666

GI number: 17230666

Start: 3842920

End: 3843465

Strand: Reverse

Name: cobU [H]

Synonym: all3174

Alternate gene names: 17230666

Gene position: 3843465-3842920 (Counterclockwise)

Preceding gene: 17230671

Following gene: 17230665

Centisome position: 59.93

GC content: 46.34

Gene sequence:

>546_bases
GTGATCTTAATTACGGGGCCGGCTAGGTCTGGAAAAAGTGAATGGGCAGAGATTTGGGCAAGAGAGTCAGGGAAGACGGT
GATTTACGTGGCTACAGCAACCAGTAACCCGGATGATGCAGAATGGCAAGAACGTATTCAACAACATCAAAACCGCCGTC
CTCAAGATTGGATAACCCTAGAAGTTCCAACTACATTATCTATGACTCTGGCAGATACCAAGGCTAACAGTTGTGTTTTG
GTAGATTCTCTGGGAACTTGGGTAGCGAATCTTTTAGAACAAGATGAAGTTAGTTGGGCAAGCACTGTAGCAGAATTTTT
GGTAACAGTACAGCTAGTTGCGGCTGATATGGTTTTTGTGGCGGAAGAAACTGGTTGGGGCATAGTGCCAGCATACCCTT
TAGGAAGGAAATTCCGCGATCGCCTTGGTGCTTTAGTCCGCCAATTAGGTGGGATGTGCGATAGCGTTTACTTAGTCACT
GGCGGTTATGCTCTCAATCTCACCGCTTTGGCAACACGATTACCAGACTCAACAGATTACGAATGA

Upstream 100 bases:

>100_bases
TTAATTTTGAATTTTGAATTTTGAATTTTGAATTGGTATTACACCCTTCCGAAAAGAAAATTAATCCGATAAATCAATTG
GGGAAACAACTTTGGGACAA

Downstream 100 bases:

>100_bases
TTAAGTATTAATTAATAAATATTAAGAGAACTTGATTATTATTTTGCTGTGCAAAGTCAGACACTTTCTTAATAGAAAAT
TAAGTAGTTAGTCTGCAAAA

Product: adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MILITGPARSGKSEWAEIWARESGKTVIYVATATSNPDDAEWQERIQQHQNRRPQDWITLEVPTTLSMTLADTKANSCVL
VDSLGTWVANLLEQDEVSWASTVAEFLVTVQLVAADMVFVAEETGWGIVPAYPLGRKFRDRLGALVRQLGGMCDSVYLVT
GGYALNLTALATRLPDSTDYE

Sequences:

>Translated_181_residues
MILITGPARSGKSEWAEIWARESGKTVIYVATATSNPDDAEWQERIQQHQNRRPQDWITLEVPTTLSMTLADTKANSCVL
VDSLGTWVANLLEQDEVSWASTVAEFLVTVQLVAADMVFVAEETGWGIVPAYPLGRKFRDRLGALVRQLGGMCDSVYLVT
GGYALNLTALATRLPDSTDYE
>Mature_181_residues
MILITGPARSGKSEWAEIWARESGKTVIYVATATSNPDDAEWQERIQQHQNRRPQDWITLEVPTTLSMTLADTKANSCVL
VDSLGTWVANLLEQDEVSWASTVAEFLVTVQLVAADMVFVAEETGWGIVPAYPLGRKFRDRLGALVRQLGGMCDSVYLVT
GGYALNLTALATRLPDSTDYE

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=182, Percent_Identity=35.1648351648352, Blast_Score=90, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 19952; Mature: 19952

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILITGPARSGKSEWAEIWARESGKTVIYVATATSNPDDAEWQERIQQHQNRRPQDWITL
CEEEECCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEE
EVPTTLSMTLADTKANSCVLVDSLGTWVANLLEQDEVSWASTVAEFLVTVQLVAADMVFV
EECCEEEEEEECCCCCCEEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEE
AEETGWGIVPAYPLGRKFRDRLGALVRQLGGMCDSVYLVTGGYALNLTALATRLPDSTDY
EECCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEHHHHHHHCCCCCCC
E
C
>Mature Secondary Structure
MILITGPARSGKSEWAEIWARESGKTVIYVATATSNPDDAEWQERIQQHQNRRPQDWITL
CEEEECCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEE
EVPTTLSMTLADTKANSCVLVDSLGTWVANLLEQDEVSWASTVAEFLVTVQLVAADMVFV
EECCEEEEEEECCCCCCEEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEE
AEETGWGIVPAYPLGRKFRDRLGALVRQLGGMCDSVYLVTGGYALNLTALATRLPDSTDY
EECCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEHHHHHHHCCCCCCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]