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The map label for this gene is pbpG [H]

Identifier: 17230473

GI number: 17230473

Start: 3621686

End: 3623608

Strand: Reverse

Name: pbpG [H]

Synonym: all2981

Alternate gene names: 17230473

Gene position: 3623608-3621686 (Counterclockwise)

Preceding gene: 17230481

Following gene: 17230469

Centisome position: 56.5

GC content: 46.13

Gene sequence:

>1923_bases
GTGTCGTCTAGGACTTTTGAACAAAAGCAACCGCAACGTCGTACTTCGTCGGGATTTGAGTTTTTTAAAGGAGTAGGCCA
GATAGCTGGCGGCACTCTGTTATCACTGACGATGTTGACAAGCTCCATTGTAGCCGGAGGGCTTGTTGGTTTAGCGATCA
GTTTCCGGAATTTACCAGATGTCAGACAGCTACGTAATTTCTTCCCATCGGAAACAACTTACATCTACGATATTAAGGGC
AAACTACTAGCTAGTGTCCACGGGGAAGCCAACCGCGAAGTCGTACCTTTAGATAGAATTTCCCCCAATCTGAAACGGGC
TGTACTCGCCAGTGAAGATAGTCATTTCTATTATCACCACGGTATTAACCCCACTGGTGTAGGGCGTGCTGTTGTCACTA
ACTTAGCGGCGGGTGGTGTAAAAGAAGGTGGTTCTACCATCACCATGCAGTTGGTGAAAAACCTATTTTTGACTCGGAGG
CGTGCCTTTACTCGGAAGCTAGCCGAGGGAGTACTGGCAATTCGGTTAGAACAAATTCTCACAAAAGACCAAATTTTAGA
AATGTACCTCAATCAAGTGTATTGGGGTCACAATAATTATGGGGTGCAAACAGCAGCACGGAGTTACTTTAATAAGTCAT
CTGAGAACTTAACTATCGCTGAATCAGCGATGATGGCGGGTTTAATCCAAGCACCAGAAGAATTTAGCCCATTTGCCAGC
AAAAAGTTAGCCCAGCAGAAACAAAAAGAAGTACTGGGGCGGATGCTGGAATTGGACTGGATTACCCAGAAAGAATATGA
TGATGCTCTCAAGGAAGAACTTACATTCGGTAGAATTAAGTCTTTTCAAGGTAGTGCGCTGCCATATATAACCAACACTG
TGTCCCAGGAACTAGCGAAAAAGTTTGGTCGTGAAACCCTGCTGAAGGGTGGTATGCGGGTACAAACTACAGTCGATGCT
AATTTCCAAACAATGGCGGAAGACACTGTGAAGAAATGGCATAAAACTCTACTTGGTGAAGGATTAAGTAGAAATCAAAT
TGCACTGGTAGCTATTGACCCCAGGACTCATTTTGTCAAAGCCCTAGTCGGTGGTGTAGACTCTAGAGCTAGTGAGTTTA
ACCGCGCTACACAAGCTCTACGTCAACCGGGATCTTCCTTTAAACCGTTTGTTTACTATGCTGCTTTTGCTACTGGGAAA
TTTGCACCTGATAGCACGGTGATAGATGCCCCAGTGAGGTATCGAGATGGTAATAATTGGTATAGTCCTAGAAACTATGA
TGGTGGCTTTAGCGGTGCCATGTCCATCCGCACTGCCCTAGCGCAATCACGTAACATTCCTGTGATTAAACTGGGTAAAA
CCATTGGCATGAATAAAGTAGTGGAAACTTGCCGCATTTTGGGTATCATGAGTCCGATGGAACCTGTGACCTCCCTGCCA
CTAGGGGCGATTGGTGTCACGCCACTAGAAATGGCTAGTGCTTATGCGACTTTTGCCAATTATGGTTGGCAATCACCGCC
GACCGTTATTGCCCGGATTACTGATAGCAGTGGTAATGTGTTATTAGATAATACTCCCAAACCCCAGCTAGTGTTAGATC
CTTGGGCATCGGCAGCGATTATAGATGTGATGCGATCGGTTGTTACTAATGGTACTGGTAAAGGTGCTGCGATAGATCGC
CCATCTGCGGGGAAAACAGGTACAACCTCATCTGAAAAAGATATTTGGTACGTGGGTACTGTACCGCAGTTAACAACTGC
GGTCTGGATAGGTAGAGATGACAACCGACAACTAGCCAGTGGTGCAACTGGTGGTGGGAAGGTTGCTCCCATCTGGCGTG
ATTTTATGACTAAGGCACTCAAGGGCGTGCCGGTGCAAAACTTCAAGCCGCCTTCCCAATTTCCGCGTCCTAAGGCGAAT
TAA

Upstream 100 bases:

>100_bases
GTTATTTCATCTGCCAAACTAATATAATTGCAAAAAATTAACCGCCCTGCTTCAAAGAATGAATTACAGTAATATTTACA
AGTGAGGAAGTGAAATCGCC

Downstream 100 bases:

>100_bases
GGGACTGGGTATCGGGGATGGGAGAATTGGTCACTTTCTCTTCCCTGCCGCCTCCTGCGCTGTACGCCCTGCTGCTGTGC
TTGCTTCCTAGTACCTAATC

Product: penicillin-binding protein

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 640; Mature: 639

Protein sequence:

>640_residues
MSSRTFEQKQPQRRTSSGFEFFKGVGQIAGGTLLSLTMLTSSIVAGGLVGLAISFRNLPDVRQLRNFFPSETTYIYDIKG
KLLASVHGEANREVVPLDRISPNLKRAVLASEDSHFYYHHGINPTGVGRAVVTNLAAGGVKEGGSTITMQLVKNLFLTRR
RAFTRKLAEGVLAIRLEQILTKDQILEMYLNQVYWGHNNYGVQTAARSYFNKSSENLTIAESAMMAGLIQAPEEFSPFAS
KKLAQQKQKEVLGRMLELDWITQKEYDDALKEELTFGRIKSFQGSALPYITNTVSQELAKKFGRETLLKGGMRVQTTVDA
NFQTMAEDTVKKWHKTLLGEGLSRNQIALVAIDPRTHFVKALVGGVDSRASEFNRATQALRQPGSSFKPFVYYAAFATGK
FAPDSTVIDAPVRYRDGNNWYSPRNYDGGFSGAMSIRTALAQSRNIPVIKLGKTIGMNKVVETCRILGIMSPMEPVTSLP
LGAIGVTPLEMASAYATFANYGWQSPPTVIARITDSSGNVLLDNTPKPQLVLDPWASAAIIDVMRSVVTNGTGKGAAIDR
PSAGKTGTTSSEKDIWYVGTVPQLTTAVWIGRDDNRQLASGATGGGKVAPIWRDFMTKALKGVPVQNFKPPSQFPRPKAN

Sequences:

>Translated_640_residues
MSSRTFEQKQPQRRTSSGFEFFKGVGQIAGGTLLSLTMLTSSIVAGGLVGLAISFRNLPDVRQLRNFFPSETTYIYDIKG
KLLASVHGEANREVVPLDRISPNLKRAVLASEDSHFYYHHGINPTGVGRAVVTNLAAGGVKEGGSTITMQLVKNLFLTRR
RAFTRKLAEGVLAIRLEQILTKDQILEMYLNQVYWGHNNYGVQTAARSYFNKSSENLTIAESAMMAGLIQAPEEFSPFAS
KKLAQQKQKEVLGRMLELDWITQKEYDDALKEELTFGRIKSFQGSALPYITNTVSQELAKKFGRETLLKGGMRVQTTVDA
NFQTMAEDTVKKWHKTLLGEGLSRNQIALVAIDPRTHFVKALVGGVDSRASEFNRATQALRQPGSSFKPFVYYAAFATGK
FAPDSTVIDAPVRYRDGNNWYSPRNYDGGFSGAMSIRTALAQSRNIPVIKLGKTIGMNKVVETCRILGIMSPMEPVTSLP
LGAIGVTPLEMASAYATFANYGWQSPPTVIARITDSSGNVLLDNTPKPQLVLDPWASAAIIDVMRSVVTNGTGKGAAIDR
PSAGKTGTTSSEKDIWYVGTVPQLTTAVWIGRDDNRQLASGATGGGKVAPIWRDFMTKALKGVPVQNFKPPSQFPRPKAN
>Mature_639_residues
SSRTFEQKQPQRRTSSGFEFFKGVGQIAGGTLLSLTMLTSSIVAGGLVGLAISFRNLPDVRQLRNFFPSETTYIYDIKGK
LLASVHGEANREVVPLDRISPNLKRAVLASEDSHFYYHHGINPTGVGRAVVTNLAAGGVKEGGSTITMQLVKNLFLTRRR
AFTRKLAEGVLAIRLEQILTKDQILEMYLNQVYWGHNNYGVQTAARSYFNKSSENLTIAESAMMAGLIQAPEEFSPFASK
KLAQQKQKEVLGRMLELDWITQKEYDDALKEELTFGRIKSFQGSALPYITNTVSQELAKKFGRETLLKGGMRVQTTVDAN
FQTMAEDTVKKWHKTLLGEGLSRNQIALVAIDPRTHFVKALVGGVDSRASEFNRATQALRQPGSSFKPFVYYAAFATGKF
APDSTVIDAPVRYRDGNNWYSPRNYDGGFSGAMSIRTALAQSRNIPVIKLGKTIGMNKVVETCRILGIMSPMEPVTSLPL
GAIGVTPLEMASAYATFANYGWQSPPTVIARITDSSGNVLLDNTPKPQLVLDPWASAAIIDVMRSVVTNGTGKGAAIDRP
SAGKTGTTSSEKDIWYVGTVPQLTTAVWIGRDDNRQLASGATGGGKVAPIWRDFMTKALKGVPVQNFKPPSQFPRPKAN

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=531, Percent_Identity=33.5216572504708, Blast_Score=256, Evalue=4e-69,
Organism=Escherichia coli, GI87082258, Length=300, Percent_Identity=39, Blast_Score=212, Evalue=8e-56,
Organism=Escherichia coli, GI1788867, Length=517, Percent_Identity=29.9806576402321, Blast_Score=199, Evalue=5e-52,
Organism=Escherichia coli, GI1789601, Length=185, Percent_Identity=32.4324324324324, Blast_Score=101, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.1.129; 3.4.-.- [C]

Molecular weight: Translated: 70025; Mature: 69894

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRTFEQKQPQRRTSSGFEFFKGVGQIAGGTLLSLTMLTSSIVAGGLVGLAISFRNLPD
CCCCCCCHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
VRQLRNFFPSETTYIYDIKGKLLASVHGEANREVVPLDRISPNLKRAVLASEDSHFYYHH
HHHHHHHCCCCCEEEEEECCHHHEECCCCCCCEEEEHHHCCCCHHHHHEECCCCCEEEEC
GINPTGVGRAVVTNLAAGGVKEGGSTITMQLVKNLFLTRRRAFTRKLAEGVLAIRLEQIL
CCCCCCCHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKDQILEMYLNQVYWGHNNYGVQTAARSYFNKSSENLTIAESAMMAGLIQAPEEFSPFAS
HHHHHHHHHHHHHEECCCCCCHHHHHHHHHCCCCCCEEHHHHHHHHHHHHCCHHCCHHHH
KKLAQQKQKEVLGRMLELDWITQKEYDDALKEELTFGRIKSFQGSALPYITNTVSQELAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
KFGRETLLKGGMRVQTTVDANFQTMAEDTVKKWHKTLLGEGLSRNQIALVAIDPRTHFVK
HHCHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHH
ALVGGVDSRASEFNRATQALRQPGSSFKPFVYYAAFATGKFAPDSTVIDAPVRYRDGNNW
HHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCEEECCEEEECCCCC
YSPRNYDGGFSGAMSIRTALAQSRNIPVIKLGKTIGMNKVVETCRILGIMSPMEPVTSLP
CCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHCC
LGAIGVTPLEMASAYATFANYGWQSPPTVIARITDSSGNVLLDNTPKPQLVLDPWASAAI
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEECCCCCCCEEECCCHHHHH
IDVMRSVVTNGTGKGAAIDRPSAGKTGTTSSEKDIWYVGTVPQLTTAVWIGRDDNRQLAS
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHEEEEECCCCCCHHHC
GATGGGKVAPIWRDFMTKALKGVPVQNFKPPSQFPRPKAN
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSRTFEQKQPQRRTSSGFEFFKGVGQIAGGTLLSLTMLTSSIVAGGLVGLAISFRNLPD
CCCCCCHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
VRQLRNFFPSETTYIYDIKGKLLASVHGEANREVVPLDRISPNLKRAVLASEDSHFYYHH
HHHHHHHCCCCCEEEEEECCHHHEECCCCCCCEEEEHHHCCCCHHHHHEECCCCCEEEEC
GINPTGVGRAVVTNLAAGGVKEGGSTITMQLVKNLFLTRRRAFTRKLAEGVLAIRLEQIL
CCCCCCCHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKDQILEMYLNQVYWGHNNYGVQTAARSYFNKSSENLTIAESAMMAGLIQAPEEFSPFAS
HHHHHHHHHHHHHEECCCCCCHHHHHHHHHCCCCCCEEHHHHHHHHHHHHCCHHCCHHHH
KKLAQQKQKEVLGRMLELDWITQKEYDDALKEELTFGRIKSFQGSALPYITNTVSQELAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
KFGRETLLKGGMRVQTTVDANFQTMAEDTVKKWHKTLLGEGLSRNQIALVAIDPRTHFVK
HHCHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHH
ALVGGVDSRASEFNRATQALRQPGSSFKPFVYYAAFATGKFAPDSTVIDAPVRYRDGNNW
HHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCEEECCEEEECCCCC
YSPRNYDGGFSGAMSIRTALAQSRNIPVIKLGKTIGMNKVVETCRILGIMSPMEPVTSLP
CCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHCC
LGAIGVTPLEMASAYATFANYGWQSPPTVIARITDSSGNVLLDNTPKPQLVLDPWASAAI
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEECCCCCCCEEECCCHHHHH
IDVMRSVVTNGTGKGAAIDRPSAGKTGTTSSEKDIWYVGTVPQLTTAVWIGRDDNRQLAS
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHEEEEECCCCCCHHHC
GATGGGKVAPIWRDFMTKALKGVPVQNFKPPSQFPRPKAN
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]