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The map label for this gene is lepB1 [H]

Identifier: 17230467

GI number: 17230467

Start: 3618030

End: 3618602

Strand: Direct

Name: lepB1 [H]

Synonym: alr2975

Alternate gene names: 17230467

Gene position: 3618030-3618602 (Clockwise)

Preceding gene: 17230466

Following gene: 17230470

Centisome position: 56.41

GC content: 43.63

Gene sequence:

>573_bases
ATGAATCCTCAGGAAAGTGATACGAAACAAGCCTCTACACCATCGAAAGCATGGCGAGGTTGGCAAGAAAATTTAACGCT
CATAGCGATCGCTTTATGTTTAGCCCTATTAATTCGGACATTCATAGCCGAACCCCGCTACATACCTTCAGAATCAATGG
TTCCTACTTTATATGAAGGCGATCGCTTAGTAGTGGAAAAAGTCTCTTACAATTTTCAACAACCAACAACTGGGGATATA
GTCGTTTTTCAGCCACCCGCAGAACTACAACGCCGGGGATACCCCAAAGACCAAGCCTTTATCAAACGAGTAATTGGTAC
ACCAGGAGAAATCATCAGCGTTAACAATGGCAAAGTCTACTTAAACGGGAAAGCATTACCAGAAGACTACATTGCAGAAC
CACCCAATCAACCATTTCCACCAGTCAAAGTCCCAGAGAACCAATTCTTCGTCATGGGAGACAACCGCAACAATAGCAAT
GACTCCCGCTACTGGGGCTTTTTACCCAAGGAGAATATCATTGGTAGGGCAGTATTTCGCTTTTGGCCTCTGGATCGTTT
AGGAATAATTTAA

Upstream 100 bases:

>100_bases
ACACCCTTAAACACTCGTAAAATATAGAATTTGGCTGCATAAGTCCTAATAGAATAATCAAAGTATTTGTTTTACATAAT
TCAACTGGCCAAAAACTTCT

Downstream 100 bases:

>100_bases
ATAGGACTTACGCATGAAAACAAAAAATCAAGGTTTGGAAAGGGGTGTAGGGGTATAGGGGTGTAAATGTTTAACATCCT
TACACCCAGTCTCAACAGAC

Product: hypothetical protein

Products: NA

Alternate protein names: SPase I-1; Leader peptidase I-1 [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MNPQESDTKQASTPSKAWRGWQENLTLIAIALCLALLIRTFIAEPRYIPSESMVPTLYEGDRLVVEKVSYNFQQPTTGDI
VVFQPPAELQRRGYPKDQAFIKRVIGTPGEIISVNNGKVYLNGKALPEDYIAEPPNQPFPPVKVPENQFFVMGDNRNNSN
DSRYWGFLPKENIIGRAVFRFWPLDRLGII

Sequences:

>Translated_190_residues
MNPQESDTKQASTPSKAWRGWQENLTLIAIALCLALLIRTFIAEPRYIPSESMVPTLYEGDRLVVEKVSYNFQQPTTGDI
VVFQPPAELQRRGYPKDQAFIKRVIGTPGEIISVNNGKVYLNGKALPEDYIAEPPNQPFPPVKVPENQFFVMGDNRNNSN
DSRYWGFLPKENIIGRAVFRFWPLDRLGII
>Mature_190_residues
MNPQESDTKQASTPSKAWRGWQENLTLIAIALCLALLIRTFIAEPRYIPSESMVPTLYEGDRLVVEKVSYNFQQPTTGDI
VVFQPPAELQRRGYPKDQAFIKRVIGTPGEIISVNNGKVYLNGKALPEDYIAEPPNQPFPPVKVPENQFFVMGDNRNNSN
DSRYWGFLPKENIIGRAVFRFWPLDRLGII

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=110, Percent_Identity=36.3636363636364, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 21611; Mature: 21611

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPQESDTKQASTPSKAWRGWQENLTLIAIALCLALLIRTFIAEPRYIPSESMVPTLYEG
CCCCCCCCCCCCCCHHHHCCHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECC
DRLVVEKVSYNFQQPTTGDIVVFQPPAELQRRGYPKDQAFIKRVIGTPGEIISVNNGKVY
CEEEEEECCCCCCCCCCCCEEEECCCHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCEEE
LNGKALPEDYIAEPPNQPFPPVKVPENQFFVMGDNRNNSNDSRYWGFLPKENIIGRAVFR
ECCCCCCHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEECCCCCCHHHHHHHHH
FWPLDRLGII
HCCCHHHCCC
>Mature Secondary Structure
MNPQESDTKQASTPSKAWRGWQENLTLIAIALCLALLIRTFIAEPRYIPSESMVPTLYEG
CCCCCCCCCCCCCCHHHHCCHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECC
DRLVVEKVSYNFQQPTTGDIVVFQPPAELQRRGYPKDQAFIKRVIGTPGEIISVNNGKVY
CEEEEEECCCCCCCCCCCCEEEECCCHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCEEE
LNGKALPEDYIAEPPNQPFPPVKVPENQFFVMGDNRNNSNDSRYWGFLPKENIIGRAVFR
ECCCCCCHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEECCCCCCHHHHHHHHH
FWPLDRLGII
HCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]