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The map label for this gene is glk [H]

Identifier: 17230465

GI number: 17230465

Start: 3616207

End: 3617235

Strand: Direct

Name: glk [H]

Synonym: alr2973

Alternate gene names: 17230465

Gene position: 3616207-3617235 (Clockwise)

Preceding gene: 17230464

Following gene: 17230466

Centisome position: 56.38

GC content: 44.22

Gene sequence:

>1029_bases
ATGACCTTATTGTTAGCAGGAGATATCGGCGGGACGAAAACGATTTTGCGATTGGTAGAAATATCAAATTCGTCGGAACT
GCACAATATTTATGAGGAAAGTTACCAGAGTGGGGATTTTCCAGATTTAGTGCCGATGGTGCAGCAATTCTTAGTCAAGG
CTAATATACCTAGTCACCCCGAAAAGGCTTGCTTTGCGATCGCTGGCCCTGTGGTGAATAATACTGCCAAACTGACCAAT
TTAGTCTGGTTTTTGGACACTGAACGGCTAGCACAAGAATTAAGTATTCCCTTCATTTCCTTAATTAATGATTTTGCTGC
TGTTGGCTATGGGATTTTTGGGTTAAATAAACAAGACTTGCTGACCTTACAAGCTGGTAAACATCAACCAGAAGCACCTA
TTGCTATTATTGGTGCTGGCACTGGATTAGGACAAGGATTTTTAATTAAACAGGGAAACCAGTATCAAGTTTTCCCCTCG
GAAGGTGGACACGCCGACTTTGCCCCCCGCAACGAGTTAGAGTTTCAGTTGTTGAAATATCTGCTGGATAAACATGATAT
CCAGCGCGTTTCTGTGGAAAGGGTGGTTTCTGGACAGGGGATTGTCGCCATTTATCAATTTTTACGCGATCGCAAACTCG
CTACAGAATCGCCAGAAATTGCTCAAGTTGTCCGCACTTGGGAACAACAAGCAGGACAGGCTGAAAAAACCGTTGATCCT
GGTGCGGCTATTGGTAAAGCCGCAGTCCAAGGAAGCGATCGCCTTTCGGAACAAGCCCTACAATTATTTATCGATGCTTA
CGGTGCAGAAGCGGGAAATCTTGCCCTCAAACTCCTACCATACGGCGGCTTGTACATTGCGGGTGGGATTGCGCCTAAAA
TCCTACCTTTGATTGAAAATAGCAATTTTTTGCTTAATTTCAGCCAAAAAGGCAGAATGCGTCCTCTGCTAGCAGAAATA
CCGGTGCATATTATTCTCAATCAACAAGTGGGACTCATAGGTGCTGCTTTGTGTGCTGCTAGGTTATAA

Upstream 100 bases:

>100_bases
CGGGAAACCCGCCCACGGGGGCGGCTCAGGAACGCACTATGTCACTGTTGACTATGGACTAATGATTCATGACCACTAAC
TAAATTTACTGATAAATGTT

Downstream 100 bases:

>100_bases
CAGCTAGCATCATCAGTGATATCAGCATCTGCGAATGCTAAAACCATGACACCAAAATTTGTCTTACCATTAATCGCTGC
TACCATAGTTTGTAGTGGTT

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTLLLAGDIGGTKTILRLVEISNSSELHNIYEESYQSGDFPDLVPMVQQFLVKANIPSHPEKACFAIAGPVVNNTAKLTN
LVWFLDTERLAQELSIPFISLINDFAAVGYGIFGLNKQDLLTLQAGKHQPEAPIAIIGAGTGLGQGFLIKQGNQYQVFPS
EGGHADFAPRNELEFQLLKYLLDKHDIQRVSVERVVSGQGIVAIYQFLRDRKLATESPEIAQVVRTWEQQAGQAEKTVDP
GAAIGKAAVQGSDRLSEQALQLFIDAYGAEAGNLALKLLPYGGLYIAGGIAPKILPLIENSNFLLNFSQKGRMRPLLAEI
PVHIILNQQVGLIGAALCAARL

Sequences:

>Translated_342_residues
MTLLLAGDIGGTKTILRLVEISNSSELHNIYEESYQSGDFPDLVPMVQQFLVKANIPSHPEKACFAIAGPVVNNTAKLTN
LVWFLDTERLAQELSIPFISLINDFAAVGYGIFGLNKQDLLTLQAGKHQPEAPIAIIGAGTGLGQGFLIKQGNQYQVFPS
EGGHADFAPRNELEFQLLKYLLDKHDIQRVSVERVVSGQGIVAIYQFLRDRKLATESPEIAQVVRTWEQQAGQAEKTVDP
GAAIGKAAVQGSDRLSEQALQLFIDAYGAEAGNLALKLLPYGGLYIAGGIAPKILPLIENSNFLLNFSQKGRMRPLLAEI
PVHIILNQQVGLIGAALCAARL
>Mature_341_residues
TLLLAGDIGGTKTILRLVEISNSSELHNIYEESYQSGDFPDLVPMVQQFLVKANIPSHPEKACFAIAGPVVNNTAKLTNL
VWFLDTERLAQELSIPFISLINDFAAVGYGIFGLNKQDLLTLQAGKHQPEAPIAIIGAGTGLGQGFLIKQGNQYQVFPSE
GGHADFAPRNELEFQLLKYLLDKHDIQRVSVERVVSGQGIVAIYQFLRDRKLATESPEIAQVVRTWEQQAGQAEKTVDPG
AAIGKAAVQGSDRLSEQALQLFIDAYGAEAGNLALKLLPYGGLYIAGGIAPKILPLIENSNFLLNFSQKGRMRPLLAEIP
VHIILNQQVGLIGAALCAARL

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788732, Length=331, Percent_Identity=33.2326283987915, Blast_Score=167, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003836 [H]

Pfam domain/function: PF02685 Glucokinase [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 37064; Mature: 36933

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLLAGDIGGTKTILRLVEISNSSELHNIYEESYQSGDFPDLVPMVQQFLVKANIPSHP
CEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCC
EKACFAIAGPVVNNTAKLTNLVWFLDTERLAQELSIPFISLINDFAAVGYGIFGLNKQDL
CHHHEEEECCHHCCCHHHHHEEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHE
LTLQAGKHQPEAPIAIIGAGTGLGQGFLIKQGNQYQVFPSEGGHADFAPRNELEFQLLKY
EEEECCCCCCCCCEEEEECCCCCCCCEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHH
LLDKHDIQRVSVERVVSGQGIVAIYQFLRDRKLATESPEIAQVVRTWEQQAGQAEKTVDP
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
GAAIGKAAVQGSDRLSEQALQLFIDAYGAEAGNLALKLLPYGGLYIAGGIAPKILPLIEN
CHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCHHHHHEECC
SNFLLNFSQKGRMRPLLAEIPVHIILNQQVGLIGAALCAARL
CCEEEEECCCCCCCCHHHHCCEEEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TLLLAGDIGGTKTILRLVEISNSSELHNIYEESYQSGDFPDLVPMVQQFLVKANIPSHP
EEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCC
EKACFAIAGPVVNNTAKLTNLVWFLDTERLAQELSIPFISLINDFAAVGYGIFGLNKQDL
CHHHEEEECCHHCCCHHHHHEEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHE
LTLQAGKHQPEAPIAIIGAGTGLGQGFLIKQGNQYQVFPSEGGHADFAPRNELEFQLLKY
EEEECCCCCCCCCEEEEECCCCCCCCEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHH
LLDKHDIQRVSVERVVSGQGIVAIYQFLRDRKLATESPEIAQVVRTWEQQAGQAEKTVDP
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
GAAIGKAAVQGSDRLSEQALQLFIDAYGAEAGNLALKLLPYGGLYIAGGIAPKILPLIEN
CHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCHHHHHEECC
SNFLLNFSQKGRMRPLLAEIPVHIILNQQVGLIGAALCAARL
CCEEEEECCCCCCCCHHHHCCEEEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA