Click here to switch to the map view.

The map label for this gene is aphB

Identifier: 17230391

GI number: 17230391

Start: 3537722

End: 3539977

Strand: Reverse

Name: aphB

Synonym: all2899

Alternate gene names: 17230391

Gene position: 3539977-3537722 (Counterclockwise)

Preceding gene: 17230392

Following gene: 17230390

Centisome position: 55.19

GC content: 38.83

Gene sequence:

>2256_bases
GTGAACATCAACGATATCACTATTCCCTTTCAGGTAGACCTCAGTAACTGTAGCAAAGAGCCAATTCATATTCCTGGGTT
AATTCAACCTCATGGAGTACTTTTAGTATTACAAGAAGTAGACTTAACGATTCTGCAAGTTAGTAATAATACATTCAATA
TTTTGGGAAGACATCCCGAACAGTTACTCAATCAACATTTAAGCTGTTTACTAGAAGCGGAACAACTTAGTTTATTAAAG
GATTGTTTGGCACAGGAAGATTTACAAATTATTAATCCCCTGGAATTTATTATAAAATCCCATAACGAAAGCATTAGTTT
TGATGTTATTGCCCATCGTTCTAATAATTTGTTAATTTTAGAATTAGAAGCTAATTTATCAGACAAAACCCATTCGTTTT
TCCGATTTTATCACCTTGTAAAACTAGCGATGCTAAAACTACAAGGTACAGCAACCACAACAGAAATCAGCCAGATATTA
GCTCAAGAAGTCCGGAAAATTACTGGCTTTGATAGAGTGATGGTTTATCGTTTTGATGAACAGTGGAATGGTAAAGTTAT
TGCCGAAGTAAAACCAGAATATCTTACATCTTATTTAGGGTTAAATTATCCAGCATCTGATATTCCACAACAAGCTAGAA
AACTCTATAGCCAAAACTGGCTGAGGTTAATCCCAGATGCTAAATATCAACCAGTACCAATTGTTCCCATTAATAATCCC
CTCAATGACCAGCCTTTAGATTTAAGTCGCTCAGTTCTTCGCAGCGTCTCCCCATTACACATTGAATATATGCAGAATAT
GGGCGTGACAGCTTCTATGTCGATTTCAATCATGAAAAATCAGAAGTTATGGGGACTCATTGCCTGCCATCATCAATCAC
CAAAATATATACCCTATGAAATACGGAGCGCCTGTGAATTTTTAGGACAAATGACTTCTGTAGAAATGAGTGCCAAAGAA
GATAGTGAGGATACAGAAGATAAAATTCAAGTGAAATCGGTGCATAGCAAATTAGTACAATATATGTCGGCTGAAAATGA
CTTTATTAATGCCTTAATTGACCATCAGCCGAATATACTTGACCTGGTAAAAGCACAAGGAGCAGCAGTTTGTTTTAACG
GTAATTCTTGTACAGTTGGTCAAGTTCCTCCCATGCCAGATATTCAAGTTCTTGTGGAATGGATGAGTCAAAATATACAT
GAGGAGATTTTTGCCACAGATTCACTCGCAACAGTTTACCCAGATGCCGAAAAATTACGGGATGTGGCTAGCGGCTTGAT
AGCGCTTTCTATTTCTAGAAGTCAGAAAAACTATATTTTATGGTTTCGGCCAGAGGTGGTAAGAACTGTAGATTGGGGAG
GAAATCCTCATAAACCTGTAGAAGTTATAGCAAATGGTGAAATACGCCTATCACCTCGCAAGTCTTTTGATTTATGGAAA
GAAACTGTACTTTTAAAATCACAACCGTGGAAATCTCATGAAGTGAATGCAGCACTAGAGTTAAGAAGCGCAATTATTGG
TATAGTGTTGCAAAAAGCGGATGAACTAGCACAGCTCAATATTGAACTGGAACGCAGCAATCAGGAACTAGATGCTTTTG
CTTATATCGCTTCTCACGATTTGAAAGAACCACTAAGGGGAATTCATAATTATTCTAATTTTTTGATGGAAGATTATGGC
GAAATTATCGATGCACCAGGAAAGGAAAAGTTACTCACCCTGATTCGTCTCACCCAACGGATGGAAGATTTGATTGATTC
GCTGCTGCATTTTTCCCGTTTGGGACGGGTTGATTTATCCATGCAGGACACCGACCTCAATGAAATTGTGCATCGCATTC
TAGATATGTTAAGTGGGCGAATTGAGGAGACAGGGGTGGAAATTAGGATTTTACAATTACTGCCTGTAGTGTACTGCGAT
CGCATCCAAATCGGCGAAGTCTTCAGTAATCTGATTGCCAACTCCATCAAATACAATGACAAAGCCAACAAATGGATTGA
AATTGGCTACATCGACAATCCACCGCTACCACCCACATTTTACGTGCGAGATAATGGCATTGGTATTCGAGAAAAACACT
TTGAAACTATTTTCCGCATCTTCAAACGACTACACAGCCCTAGCAAATATGGCGGTGGTACAGGTGCAGGACTCACCATA
GCCAAAAAAATTGTCGAACGACACGGCGGTAAAATTTGGGTGGAGTCAACCTACGGCGAAGGTAGTACGTTTTATTTCAC
GCTGCAAGATGTGTAG

Upstream 100 bases:

>100_bases
TGGCTCCCCTATACCCTGATACCCGGTCTCAACAGATAACCTGTTCGCGTAAGTCCTAATCAAAAGTCTTGGTAATGGTT
GTAATTTTAAGGACTGAGAA

Downstream 100 bases:

>100_bases
CAACATGACCAATTCAAAATTTAGAGAACTTTTAAGCACTCCCCAGATGATTGGTAACAACACCCAACCTTTATTAGTAA
TTGAAGATAGCGACGAAGAC

Product: phytochrome-like protein, two-component sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 751; Mature: 751

Protein sequence:

>751_residues
MNINDITIPFQVDLSNCSKEPIHIPGLIQPHGVLLVLQEVDLTILQVSNNTFNILGRHPEQLLNQHLSCLLEAEQLSLLK
DCLAQEDLQIINPLEFIIKSHNESISFDVIAHRSNNLLILELEANLSDKTHSFFRFYHLVKLAMLKLQGTATTTEISQIL
AQEVRKITGFDRVMVYRFDEQWNGKVIAEVKPEYLTSYLGLNYPASDIPQQARKLYSQNWLRLIPDAKYQPVPIVPINNP
LNDQPLDLSRSVLRSVSPLHIEYMQNMGVTASMSISIMKNQKLWGLIACHHQSPKYIPYEIRSACEFLGQMTSVEMSAKE
DSEDTEDKIQVKSVHSKLVQYMSAENDFINALIDHQPNILDLVKAQGAAVCFNGNSCTVGQVPPMPDIQVLVEWMSQNIH
EEIFATDSLATVYPDAEKLRDVASGLIALSISRSQKNYILWFRPEVVRTVDWGGNPHKPVEVIANGEIRLSPRKSFDLWK
ETVLLKSQPWKSHEVNAALELRSAIIGIVLQKADELAQLNIELERSNQELDAFAYIASHDLKEPLRGIHNYSNFLMEDYG
EIIDAPGKEKLLTLIRLTQRMEDLIDSLLHFSRLGRVDLSMQDTDLNEIVHRILDMLSGRIEETGVEIRILQLLPVVYCD
RIQIGEVFSNLIANSIKYNDKANKWIEIGYIDNPPLPPTFYVRDNGIGIREKHFETIFRIFKRLHSPSKYGGGTGAGLTI
AKKIVERHGGKIWVESTYGEGSTFYFTLQDV

Sequences:

>Translated_751_residues
MNINDITIPFQVDLSNCSKEPIHIPGLIQPHGVLLVLQEVDLTILQVSNNTFNILGRHPEQLLNQHLSCLLEAEQLSLLK
DCLAQEDLQIINPLEFIIKSHNESISFDVIAHRSNNLLILELEANLSDKTHSFFRFYHLVKLAMLKLQGTATTTEISQIL
AQEVRKITGFDRVMVYRFDEQWNGKVIAEVKPEYLTSYLGLNYPASDIPQQARKLYSQNWLRLIPDAKYQPVPIVPINNP
LNDQPLDLSRSVLRSVSPLHIEYMQNMGVTASMSISIMKNQKLWGLIACHHQSPKYIPYEIRSACEFLGQMTSVEMSAKE
DSEDTEDKIQVKSVHSKLVQYMSAENDFINALIDHQPNILDLVKAQGAAVCFNGNSCTVGQVPPMPDIQVLVEWMSQNIH
EEIFATDSLATVYPDAEKLRDVASGLIALSISRSQKNYILWFRPEVVRTVDWGGNPHKPVEVIANGEIRLSPRKSFDLWK
ETVLLKSQPWKSHEVNAALELRSAIIGIVLQKADELAQLNIELERSNQELDAFAYIASHDLKEPLRGIHNYSNFLMEDYG
EIIDAPGKEKLLTLIRLTQRMEDLIDSLLHFSRLGRVDLSMQDTDLNEIVHRILDMLSGRIEETGVEIRILQLLPVVYCD
RIQIGEVFSNLIANSIKYNDKANKWIEIGYIDNPPLPPTFYVRDNGIGIREKHFETIFRIFKRLHSPSKYGGGTGAGLTI
AKKIVERHGGKIWVESTYGEGSTFYFTLQDV
>Mature_751_residues
MNINDITIPFQVDLSNCSKEPIHIPGLIQPHGVLLVLQEVDLTILQVSNNTFNILGRHPEQLLNQHLSCLLEAEQLSLLK
DCLAQEDLQIINPLEFIIKSHNESISFDVIAHRSNNLLILELEANLSDKTHSFFRFYHLVKLAMLKLQGTATTTEISQIL
AQEVRKITGFDRVMVYRFDEQWNGKVIAEVKPEYLTSYLGLNYPASDIPQQARKLYSQNWLRLIPDAKYQPVPIVPINNP
LNDQPLDLSRSVLRSVSPLHIEYMQNMGVTASMSISIMKNQKLWGLIACHHQSPKYIPYEIRSACEFLGQMTSVEMSAKE
DSEDTEDKIQVKSVHSKLVQYMSAENDFINALIDHQPNILDLVKAQGAAVCFNGNSCTVGQVPPMPDIQVLVEWMSQNIH
EEIFATDSLATVYPDAEKLRDVASGLIALSISRSQKNYILWFRPEVVRTVDWGGNPHKPVEVIANGEIRLSPRKSFDLWK
ETVLLKSQPWKSHEVNAALELRSAIIGIVLQKADELAQLNIELERSNQELDAFAYIASHDLKEPLRGIHNYSNFLMEDYG
EIIDAPGKEKLLTLIRLTQRMEDLIDSLLHFSRLGRVDLSMQDTDLNEIVHRILDMLSGRIEETGVEIRILQLLPVVYCD
RIQIGEVFSNLIANSIKYNDKANKWIEIGYIDNPPLPPTFYVRDNGIGIREKHFETIFRIFKRLHSPSKYGGGTGAGLTI
AKKIVERHGGKIWVESTYGEGSTFYFTLQDV

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region

COG id: COG4251

COG function: function code T; Bacteriophytochrome (light-regulated signal transduction histidine kinase)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain

Homologues:

Organism=Escherichia coli, GI48994928, Length=234, Percent_Identity=26.0683760683761, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1789149, Length=256, Percent_Identity=26.171875, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786600, Length=259, Percent_Identity=27.7992277992278, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI87081816, Length=251, Percent_Identity=26.6932270916335, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHYB_NOSS1 (Q9R6X3)

Other databases:

- EMBL:   AB034952
- EMBL:   BA000019
- PIR:   AD2168
- RefSeq:   NP_486939.1
- ProteinModelPortal:   Q9R6X3
- SMR:   Q9R6X3
- STRING:   Q9R6X3
- GeneID:   1106497
- GenomeReviews:   BA000019_GR
- KEGG:   ana:all2899
- NMPDR:   fig|103690.1.peg.3206
- eggNOG:   COG4251
- HOGENOM:   HBG639461
- OMA:   ASHDIKE
- ProtClustDB:   CLSK2461615
- BioCyc:   NSP103690:ALL2899-MONOMER
- BRENDA:   2.7.13.3
- GO:   GO:0016020
- GO:   GO:0006350
- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- Gene3D:   G3DSA:3.30.565.10
- PRINTS:   PR01033
- SMART:   SM00065
- SMART:   SM00387
- SMART:   SM00388

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome; SSF55874 ATP_bd_ATPase; SSF47384 His_kin_homodim

EC number: =2.7.13.3

Molecular weight: Translated: 85308; Mature: 85308

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS50109 HIS_KIN; PS00245 PHYTOCHROME_1; PS50046 PHYTOCHROME_2; PS00227 TUBULIN

Important sites: BINDING 17-17

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNINDITIPFQVDLSNCSKEPIHIPGLIQPHGVLLVLQEVDLTILQVSNNTFNILGRHPE
CCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCEEEEEECCCEEEEECCCHH
QLLNQHLSCLLEAEQLSLLKDCLAQEDLQIINPLEFIIKSHNESISFDVIAHRSNNLLIL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEE
ELEANLSDKTHSFFRFYHLVKLAMLKLQGTATTTEISQILAQEVRKITGFDRVMVYRFDE
EEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECC
QWNGKVIAEVKPEYLTSYLGLNYPASDIPQQARKLYSQNWLRLIPDAKYQPVPIVPINNP
CCCCEEEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEECCCC
LNDQPLDLSRSVLRSVSPLHIEYMQNMGVTASMSISIMKNQKLWGLIACHHQSPKYIPYE
CCCCCCHHHHHHHHCCCCHHHHHHHCCCCEEEEEEEEEECCCEEEEEEEECCCCCCCCHH
IRSACEFLGQMTSVEMSAKEDSEDTEDKIQVKSVHSKLVQYMSAENDFINALIDHQPNIL
HHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHH
DLVKAQGAAVCFNGNSCTVGQVPPMPDIQVLVEWMSQNIHEEIFATDSLATVYPDAEKLR
HHHHCCCCEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHH
DVASGLIALSISRSQKNYILWFRPEVVRTVDWGGNPHKPVEVIANGEIRLSPRKSFDLWK
HHHCCEEEEEEECCCCCEEEEECCCEEEEEECCCCCCCCEEEEECCEEEECCCCCHHHHH
ETVLLKSQPWKSHEVNAALELRSAIIGIVLQKADELAQLNIELERSNQELDAFAYIASHD
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHH
LKEPLRGIHNYSNFLMEDYGEIIDAPGKEKLLTLIRLTQRMEDLIDSLLHFSRLGRVDLS
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECE
MQDTDLNEIVHRILDMLSGRIEETGVEIRILQLLPVVYCDRIQIGEVFSNLIANSIKYND
ECCCCHHHHHHHHHHHHCCCHHHCCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
KANKWIEIGYIDNPPLPPTFYVRDNGIGIREKHFETIFRIFKRLHSPSKYGGGTGAGLTI
CCCCEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
AKKIVERHGGKIWVESTYGEGSTFYFTLQDV
HHHHHHHCCCEEEEEEECCCCCEEEEEEECC
>Mature Secondary Structure
MNINDITIPFQVDLSNCSKEPIHIPGLIQPHGVLLVLQEVDLTILQVSNNTFNILGRHPE
CCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCEEEEEECCCEEEEECCCHH
QLLNQHLSCLLEAEQLSLLKDCLAQEDLQIINPLEFIIKSHNESISFDVIAHRSNNLLIL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEE
ELEANLSDKTHSFFRFYHLVKLAMLKLQGTATTTEISQILAQEVRKITGFDRVMVYRFDE
EEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECC
QWNGKVIAEVKPEYLTSYLGLNYPASDIPQQARKLYSQNWLRLIPDAKYQPVPIVPINNP
CCCCEEEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEECCCC
LNDQPLDLSRSVLRSVSPLHIEYMQNMGVTASMSISIMKNQKLWGLIACHHQSPKYIPYE
CCCCCCHHHHHHHHCCCCHHHHHHHCCCCEEEEEEEEEECCCEEEEEEEECCCCCCCCHH
IRSACEFLGQMTSVEMSAKEDSEDTEDKIQVKSVHSKLVQYMSAENDFINALIDHQPNIL
HHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHH
DLVKAQGAAVCFNGNSCTVGQVPPMPDIQVLVEWMSQNIHEEIFATDSLATVYPDAEKLR
HHHHCCCCEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHH
DVASGLIALSISRSQKNYILWFRPEVVRTVDWGGNPHKPVEVIANGEIRLSPRKSFDLWK
HHHCCEEEEEEECCCCCEEEEECCCEEEEEECCCCCCCCEEEEECCEEEECCCCCHHHHH
ETVLLKSQPWKSHEVNAALELRSAIIGIVLQKADELAQLNIELERSNQELDAFAYIASHD
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHH
LKEPLRGIHNYSNFLMEDYGEIIDAPGKEKLLTLIRLTQRMEDLIDSLLHFSRLGRVDLS
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECE
MQDTDLNEIVHRILDMLSGRIEETGVEIRILQLLPVVYCDRIQIGEVFSNLIANSIKYND
ECCCCHHHHHHHHHHHHCCCHHHCCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
KANKWIEIGYIDNPPLPPTFYVRDNGIGIREKHFETIFRIFKRLHSPSKYGGGTGAGLTI
CCCCEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
AKKIVERHGGKIWVESTYGEGSTFYFTLQDV
HHHHHHHCCCEEEEEEECCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840