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The map label for this gene is dagK [H]

Identifier: 17230373

GI number: 17230373

Start: 3515023

End: 3515970

Strand: Direct

Name: dagK [H]

Synonym: alr2881

Alternate gene names: 17230373

Gene position: 3515023-3515970 (Clockwise)

Preceding gene: 17230372

Following gene: 17230374

Centisome position: 54.8

GC content: 40.3

Gene sequence:

>948_bases
GTGCAGGCTACGCCAACACTAATCAAATCAGATTCCTATATCTTAACCACGAATTACAAATTACGAACTCTTATGAGCCT
CCGCGCACTGCTATTAGTAAATCGTCATGCCCGCCAAGGACAAGAACGTCTATTGGAAGCAATTGATCATCTGAAAAAAT
TCAATTTTCAGTTAATTGAAGAGACAACAGAACATCCTAAACACCTTTCGCAAGTTATACATAAATATAAAGATCAAGTT
GATTTAGTTATAGTTGGGGGTGGTGATGGTACATTAAATGCTGTCGTTGACGCTTTAGTAGAGACACAATTACCTTTAGG
AATTTTGCCACTAGGAACTGCTAATGACTTAGCCAGAACATTAGGAATTTCTAACTCATTGCCTGAAGCTTGTAAAACAA
TTGCCGAAGGAGAATTAAGACGTATTGATTTAGGTTGGGTAAATGGTAAACACTTTTTTAATGTTGCCAGTTTAGGGCTA
AGTGTAAAAATTACCCGCCGACTTACTAAAGAATTTAAACGTCGTTGGGGTGTATTTGCTTATGCTGTCACAGCAATACA
AGTTATTTGGGAATCTCGTCCTTTCAGTGCGGAAATTCGCTCTAAAGATAGAGTATTCCGTGTTAAAACTGTACAAATTG
CTGTTGGAAATGGTCGCTATTACGGCGGTGGTATGGCTATAGTTCCTGATGCCAGCATTGATGACCAAAGACTAGACCTT
TATAGTTTAGAAATTAGTCATTGGTGGGAAATTATTCCCTTATTACCTGCAATGCGAAATGGCAGACACATTCATCGACA
AAACGTCCGCGCCCTCAACGGACAGGAGTTTGAAGTTTATACACGTAAACCCCGTGCCATCAATACGGATGGTGAAATCA
CAACCTACACCCCCGCCACATTTCGCGTTCTTCCTAAAGCCGTAGCTGTTTTAGTTCCGCCAGTGTGA

Upstream 100 bases:

>100_bases
TATTTGATTTATGAAATATACATAGGATGGGCAATGCCCACCGTATCATGGTTTCGGTGGGTATTGCCCACCCTACACAT
ACTGAGATTTTTATACGCCA

Downstream 100 bases:

>100_bases
GGTAGAGACGAAGCAGAGGGAAATCATAACTACTGACAACTGACAACTGACAACTGACAACTGACTTGATATCGTAAGAA
ATAATGGTGGGTGCATTTGT

Product: putative lipid kinase

Products: NA

Alternate protein names: DAG kinase; DAGK [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MQATPTLIKSDSYILTTNYKLRTLMSLRALLLVNRHARQGQERLLEAIDHLKKFNFQLIEETTEHPKHLSQVIHKYKDQV
DLVIVGGGDGTLNAVVDALVETQLPLGILPLGTANDLARTLGISNSLPEACKTIAEGELRRIDLGWVNGKHFFNVASLGL
SVKITRRLTKEFKRRWGVFAYAVTAIQVIWESRPFSAEIRSKDRVFRVKTVQIAVGNGRYYGGGMAIVPDASIDDQRLDL
YSLEISHWWEIIPLLPAMRNGRHIHRQNVRALNGQEFEVYTRKPRAINTDGEITTYTPATFRVLPKAVAVLVPPV

Sequences:

>Translated_315_residues
MQATPTLIKSDSYILTTNYKLRTLMSLRALLLVNRHARQGQERLLEAIDHLKKFNFQLIEETTEHPKHLSQVIHKYKDQV
DLVIVGGGDGTLNAVVDALVETQLPLGILPLGTANDLARTLGISNSLPEACKTIAEGELRRIDLGWVNGKHFFNVASLGL
SVKITRRLTKEFKRRWGVFAYAVTAIQVIWESRPFSAEIRSKDRVFRVKTVQIAVGNGRYYGGGMAIVPDASIDDQRLDL
YSLEISHWWEIIPLLPAMRNGRHIHRQNVRALNGQEFEVYTRKPRAINTDGEITTYTPATFRVLPKAVAVLVPPV
>Mature_315_residues
MQATPTLIKSDSYILTTNYKLRTLMSLRALLLVNRHARQGQERLLEAIDHLKKFNFQLIEETTEHPKHLSQVIHKYKDQV
DLVIVGGGDGTLNAVVDALVETQLPLGILPLGTANDLARTLGISNSLPEACKTIAEGELRRIDLGWVNGKHFFNVASLGL
SVKITRRLTKEFKRRWGVFAYAVTAIQVIWESRPFSAEIRSKDRVFRVKTVQIAVGNGRYYGGGMAIVPDASIDDQRLDL
YSLEISHWWEIIPLLPAMRNGRHIHRQNVRALNGQEFEVYTRKPRAINTDGEITTYTPATFRVLPKAVAVLVPPV

Specific function: Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthet

COG id: COG1597

COG function: function code IR; Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DAGKc domain [H]

Homologues:

Organism=Escherichia coli, GI1788402, Length=242, Percent_Identity=33.4710743801653, Blast_Score=112, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017438
- InterPro:   IPR005218
- InterPro:   IPR001206 [H]

Pfam domain/function: PF00781 DAGK_cat [H]

EC number: =2.7.1.107 [H]

Molecular weight: Translated: 35496; Mature: 35496

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQATPTLIKSDSYILTTNYKLRTLMSLRALLLVNRHARQGQERLLEAIDHLKKFNFQLIE
CCCCCCEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ETTEHPKHLSQVIHKYKDQVDLVIVGGGDGTLNAVVDALVETQLPLGILPLGTANDLART
HHHCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEEECCCHHHHHHH
LGISNSLPEACKTIAEGELRRIDLGWVNGKHFFNVASLGLSVKITRRLTKEFKRRWGVFA
HCCCCCCHHHHHHHHCCCEEEEEEEEECCCCEEEHHHCCEEEEHHHHHHHHHHHHHHHHH
YAVTAIQVIWESRPFSAEIRSKDRVFRVKTVQIAVGNGRYYGGGMAIVPDASIDDQRLDL
HHHHHHHHHHCCCCCCHHHCCCCEEEEEEEEEEEECCCEEECCCEEEECCCCCCCCCEEE
YSLEISHWWEIIPLLPAMRNGRHIHRQNVRALNGQEFEVYTRKPRAINTDGEITTYTPAT
EEEEHHHHHHHHHHHHHHCCCCEEHHCCHHHCCCCEEEEEECCCCEECCCCCEEEECCHH
FRVLPKAVAVLVPPV
HHHHHHHHHEECCCC
>Mature Secondary Structure
MQATPTLIKSDSYILTTNYKLRTLMSLRALLLVNRHARQGQERLLEAIDHLKKFNFQLIE
CCCCCCEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ETTEHPKHLSQVIHKYKDQVDLVIVGGGDGTLNAVVDALVETQLPLGILPLGTANDLART
HHHCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEEECCCHHHHHHH
LGISNSLPEACKTIAEGELRRIDLGWVNGKHFFNVASLGLSVKITRRLTKEFKRRWGVFA
HCCCCCCHHHHHHHHCCCEEEEEEEEECCCCEEEHHHCCEEEEHHHHHHHHHHHHHHHHH
YAVTAIQVIWESRPFSAEIRSKDRVFRVKTVQIAVGNGRYYGGGMAIVPDASIDDQRLDL
HHHHHHHHHHCCCCCCHHHCCCCEEEEEEEEEEEECCCEEECCCEEEECCCCCCCCCEEE
YSLEISHWWEIIPLLPAMRNGRHIHRQNVRALNGQEFEVYTRKPRAINTDGEITTYTPAT
EEEEHHHHHHHHHHHHHHCCCCEEHHCCHHHCCCCEEEEEECCCCEECCCCCEEEECCHH
FRVLPKAVAVLVPPV
HHHHHHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]